Nothing Special   »   [go: up one dir, main page]

HRP20030993B1 - Inhalation capsules - Google Patents

Inhalation capsules

Info

Publication number
HRP20030993B1
HRP20030993B1 HR20030993A HRP20030993A HRP20030993B1 HR P20030993 B1 HRP20030993 B1 HR P20030993B1 HR 20030993 A HR20030993 A HR 20030993A HR P20030993 A HRP20030993 A HR P20030993A HR P20030993 B1 HRP20030993 B1 HR P20030993B1
Authority
HR
Croatia
Prior art keywords
inhalation capsules
moisture
inhalation
admixture
physiologically acceptable
Prior art date
Application number
HR20030993A
Other languages
Croatian (hr)
Inventor
Bechtold-Peters Karoline
Hochrainer Dieter
Trunk Michael
Walz Michael
Original Assignee
Boehringer Ingelheim Pharma Gmbh & Co.Kg.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7687020&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP20030993(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Pharma Gmbh & Co.Kg. filed Critical Boehringer Ingelheim Pharma Gmbh & Co.Kg.
Publication of HRP20030993A2 publication Critical patent/HRP20030993A2/en
Publication of HRP20030993B1 publication Critical patent/HRP20030993B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001—Particle size control
    • A61M11/003—Particle size control by passing the aerosol trough sieves or filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Otolaryngology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Inhalacijske kapsule, koje kao inhalacijski prah sadrže tiotropij u smjesi s fiziološki prihvatljivom pomoćnom tvari, naznačene time, da materijal kapsula ima smanjeni sadržaj vlage TEWS vlagu ili vlagu po halogenom sušilu ispod 15%.Patent sadrži još 15 patentnih zahtjeva.Inhalation capsules containing tiotropium as a inhaled powder in admixture with a physiologically acceptable excipient, characterized in that the capsule material has a reduced moisture content of TEWS moisture or moisture per halogen dryer below 15%. The patent contains 15 more claims.

HR20030993A 2001-06-01 2003-11-28 Inhalation capsules HRP20030993B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10126924A DE10126924A1 (en) 2001-06-01 2001-06-01 Inhalation capsule contains powdered mixture of tiotropium and auxiliary, for treating asthma or chronic obstructive pulmonary disease, having capsule material of low moisture content to improve stability
PCT/EP2002/005600 WO2002098874A2 (en) 2001-06-01 2002-05-27 Inhalation capsules

Publications (2)

Publication Number Publication Date
HRP20030993A2 HRP20030993A2 (en) 2005-08-31
HRP20030993B1 true HRP20030993B1 (en) 2011-10-31

Family

ID=7687020

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20030993A HRP20030993B1 (en) 2001-06-01 2003-11-28 Inhalation capsules

Country Status (37)

Country Link
EP (2) EP1379220B1 (en)
JP (3) JP4447311B2 (en)
KR (2) KR100952321B1 (en)
CN (3) CN1512875A (en)
AR (2) AR034346A1 (en)
AT (1) ATE285752T1 (en)
AU (2) AU2002344354B2 (en)
BG (1) BG65655B1 (en)
BR (1) BR0209366A (en)
CA (1) CA2448425C (en)
CH (1) CH1379220H1 (en)
CO (1) CO5540379A2 (en)
CZ (1) CZ300284B6 (en)
DE (2) DE10126924A1 (en)
EA (1) EA005188B1 (en)
EC (2) ECSP034868A (en)
EE (1) EE05416B1 (en)
EG (1) EG24227A (en)
ES (1) ES2236590B5 (en)
HR (1) HRP20030993B1 (en)
HU (3) HU231082B1 (en)
IL (2) IL158917A0 (en)
ME (1) ME00301B (en)
MX (1) MXPA03010990A (en)
MY (1) MY126253A (en)
NO (1) NO332857B3 (en)
NZ (1) NZ530356A (en)
PE (1) PE20030071A1 (en)
PL (2) PL205714B1 (en)
PT (1) PT1379220E (en)
RS (1) RS50353B (en)
SI (1) SI1379220T1 (en)
SK (2) SK287379B6 (en)
TW (1) TWI327921B (en)
UA (1) UA75659C2 (en)
WO (1) WO2002098874A2 (en)
ZA (1) ZA200308340B (en)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MEP40108A (en) 2000-10-12 2011-02-10 Boehringer Ingelheim Pharma Novel tiotropium-containing inhalation powder
DE10126924A1 (en) * 2001-06-01 2002-12-05 Boehringer Ingelheim Pharma Inhalation capsule contains powdered mixture of tiotropium and auxiliary, for treating asthma or chronic obstructive pulmonary disease, having capsule material of low moisture content to improve stability
DE10212264A1 (en) 2002-03-20 2003-10-02 Boehringer Ingelheim Pharma Crystalline micronisate, process for its preparation and its use for the manufacture of a medicament
US20040025876A1 (en) * 2002-05-07 2004-02-12 Danforth Miller Capsules for dry powder inhalers and methods of making and using same
US7763280B2 (en) 2002-11-28 2010-07-27 Boehringer Ingelheim Pharma Gmbh & Co. Kg Tiotropium containing powder formulation for inhalation
DE10255387A1 (en) * 2002-11-28 2004-06-09 Boehringer Ingelheim Pharma Gmbh & Co. Kg New tiotropium-containing powder formulation for inhalation
DE10258360A1 (en) * 2002-12-12 2004-06-24 Boehringer Ingelheim Pharma Gmbh & Co. Kg Chamber for accommodation of disposable capsules for powder inhalers has an inner surface with protruding elements serving as distance pieces between the capsules
DE10352277A1 (en) * 2003-11-08 2005-06-02 Boehringer Ingelheim Pharma Gmbh & Co. Kg powder inhaler
SE0303269L (en) * 2003-12-03 2005-06-04 Microdrug Ag Medical product
SE0303570L (en) 2003-12-03 2005-06-04 Microdrug Ag Moisture-sensitive medical product
GB0503738D0 (en) * 2005-02-23 2005-03-30 Optinose As Powder delivery devices
US7694676B2 (en) 2005-04-22 2010-04-13 Boehringer Ingelheim Gmbh Dry powder inhaler
JP4825455B2 (en) * 2005-05-02 2011-11-30 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Powder inhaler
DE102006016901A1 (en) 2006-04-11 2007-10-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Mouthpiece for an inhaler
DE102006016904A1 (en) 2006-04-11 2007-10-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg inhaler
GB0716026D0 (en) * 2007-08-16 2007-09-26 Norton Healthcare Ltd An inhalable medicament
DE102007036411A1 (en) 2007-07-20 2009-02-12 Boehringer Ingelheim Pharma Gmbh & Co. Kg powder inhaler
DE102007052871A1 (en) * 2007-11-02 2009-05-07 Boehringer Ingelheim Pharma Gmbh & Co. Kg Capsule for receiving pharmaceutical drug formulations
WO2009098083A1 (en) * 2008-02-08 2009-08-13 Boehringer Ingelheim International Gmbh Method and device for filling capsules
EP2172190A1 (en) * 2008-10-02 2010-04-07 Laboratorios Liconsa, S.A. Inhalable particles comprising tiotropium
PL3578169T3 (en) 2009-02-26 2024-09-02 Glaxo Group Limited Pharmaceutical formulations comprising 4-{(1 r)-2-[(6-{2-[(2,6-dichlorobenzyl)oxy]ethoxy}hexyl)amino]-1-hydroxyethyl}-2-(hydroxymethyl)phenol
WO2010110760A1 (en) * 2009-03-27 2010-09-30 Mahmut Bilgic Compositions comprising water with deuterium for the prevention or treatment of allergic diseases and a process for the preparation thereof
GB0921075D0 (en) 2009-12-01 2010-01-13 Glaxo Group Ltd Novel combination of the therapeutic agents
WO2011152804A2 (en) 2010-06-03 2011-12-08 Mahmut Bilgic Process for dry powder formulations
DE202011102694U1 (en) 2011-06-29 2011-12-19 Zisser Gmbh Inhaler for home users
GB201200525D0 (en) 2011-12-19 2012-02-29 Teva Branded Pharmaceutical Prod R & D Inc An inhalable medicament
GEP201706672B (en) 2012-07-05 2017-05-25 Arven Ilac Sanayi Ve Ticaret As Dry powder inhaler compositions comprising long acting muscorinic antagonists
DE202013000774U1 (en) 2013-01-21 2013-04-15 Rhinofilt GmbH Miniaturized inhalation device for home use
US10034866B2 (en) 2014-06-19 2018-07-31 Teva Branded Pharmaceutical Products R&D, Inc. Inhalable medicament comprising tiotropium
CN108295042A (en) * 2018-03-05 2018-07-20 上海祺宇生物科技有限公司 A kind of plant hollow capsule and its capsule for sucking medicament
CN108451920A (en) * 2018-03-14 2018-08-28 绍兴康可胶囊有限公司 A kind of suction mist formula capsule and preparation method thereof
CN114848605B (en) * 2022-03-25 2023-08-11 上海方予健康医药科技有限公司 Gelatin capsule for inhalation of powder fog agent

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0418716A1 (en) * 1989-09-16 1991-03-27 Boehringer Ingelheim Kg Thienylcarboxylic acid ester of aminoalcohols, their quaternary products, their preparation and use of the compounds
EP1072258A1 (en) * 1999-07-28 2001-01-31 Greither, Peter Capsule for the release of bacteria, containing lyophilised bacteria and a method for the production thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2159524T3 (en) * 1992-06-12 2001-10-16 Teijin Ltd PHARMACEUTICAL PREPARATION TO BE ADMINISTERED INSIDE THE RESPIRATORY ROADS.
US6228394B1 (en) * 1997-10-14 2001-05-08 Boehringer Ingelheim Pharmaceuticals, Inc. Supercritical fluid extraction of mould lubricant from hard shell capsules
DE19835346A1 (en) * 1998-08-05 2000-02-10 Boehringer Ingelheim Pharma Two-part capsule for pharmaceutical preparations for powder inhalers
JP2000143502A (en) * 1998-11-11 2000-05-23 Shionogi Qualicaps Kk Inhalant preparation
ATE382386T1 (en) * 1998-11-13 2008-01-15 Jagotec Ag MULTIDOSIS DRY POWDER INHALER WITH POWDER RESERVOIR
DE19921693A1 (en) * 1999-05-12 2000-11-16 Boehringer Ingelheim Pharma Pharmaceutical composition for treating respiratory disorders, e.g. asthma, comprises combination of anticholinergic and beta-mimetic agents having synergistic bronchospasmolytic activity and reduced side-effects
EP1238661A1 (en) * 1999-10-12 2002-09-11 Kaken Pharmaceutical Co., Ltd. Powdery inhalational preparations and process for producing the same
DE10126924A1 (en) * 2001-06-01 2002-12-05 Boehringer Ingelheim Pharma Inhalation capsule contains powdered mixture of tiotropium and auxiliary, for treating asthma or chronic obstructive pulmonary disease, having capsule material of low moisture content to improve stability

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0418716A1 (en) * 1989-09-16 1991-03-27 Boehringer Ingelheim Kg Thienylcarboxylic acid ester of aminoalcohols, their quaternary products, their preparation and use of the compounds
EP1072258A1 (en) * 1999-07-28 2001-01-31 Greither, Peter Capsule for the release of bacteria, containing lyophilised bacteria and a method for the production thereof

Also Published As

Publication number Publication date
BG65655B1 (en) 2009-05-29
KR100921904B1 (en) 2009-10-16
RS50353B (en) 2009-11-10
KR20040007638A (en) 2004-01-24
PL364108A1 (en) 2004-12-13
AR084804A2 (en) 2013-06-26
WO2002098874A2 (en) 2002-12-12
ATE285752T1 (en) 2005-01-15
IL158917A0 (en) 2004-05-12
HUP0400666A2 (en) 2005-03-29
PT1379220E (en) 2005-03-31
AU2008203057C8 (en) 2017-04-06
IL158917A (en) 2008-11-03
CA2448425A1 (en) 2002-12-12
JP4787034B2 (en) 2011-10-05
EE200300595A (en) 2004-02-16
JP2008050364A (en) 2008-03-06
SI1379220T1 (en) 2005-04-30
MXPA03010990A (en) 2004-02-27
WO2002098874A3 (en) 2003-09-12
PE20030071A1 (en) 2003-03-04
PL205714B1 (en) 2010-05-31
JP2006143747A (en) 2006-06-08
JP4447311B2 (en) 2010-04-07
NZ530356A (en) 2005-05-27
EG24227A (en) 2008-11-10
CO5540379A2 (en) 2005-07-29
DE50201898D1 (en) 2005-02-03
TWI327921B (en) 2010-08-01
KR20090010140A (en) 2009-01-28
ES2236590B5 (en) 2018-03-05
HU231082B1 (en) 2020-06-29
ME00301B (en) 2011-05-10
NO332857B3 (en) 2016-01-25
PL387118A1 (en) 2004-12-13
HU230058B1 (en) 2015-06-29
CZ300284B6 (en) 2009-04-08
ECSP11004868A (en) 2011-02-28
EP1379220B1 (en) 2004-12-29
CN101697965A (en) 2010-04-28
JP2005500279A (en) 2005-01-06
HU230827B1 (en) 2018-07-30
YU93503A (en) 2006-05-25
EA200301275A1 (en) 2004-06-24
MY126253A (en) 2006-09-29
DE10126924A1 (en) 2002-12-05
AR034346A1 (en) 2004-02-18
AU2008203057A1 (en) 2008-07-31
AU2008203057C1 (en) 2017-05-18
EP1379220A2 (en) 2004-01-14
NO20035265D0 (en) 2003-11-27
CN101829072A (en) 2010-09-15
BR0209366A (en) 2004-06-08
CN1512875A (en) 2004-07-14
SK287379B6 (en) 2010-08-09
HUP0400666A3 (en) 2009-06-29
PL203801B1 (en) 2009-11-30
EA005188B1 (en) 2004-12-30
BG108380A (en) 2004-11-30
CZ20033579A3 (en) 2004-05-12
NO20035265L (en) 2003-11-27
EE05416B1 (en) 2011-06-15
CH1379220H1 (en) 2018-10-31
ECSP034868A (en) 2004-03-23
NO332857B1 (en) 2013-01-21
SK287346B6 (en) 2010-07-07
KR100952321B1 (en) 2010-04-09
SK16202003A3 (en) 2004-05-04
CA2448425C (en) 2010-12-21
EP1508330A1 (en) 2005-02-23
AU2008203057B2 (en) 2011-12-08
AU2002344354B2 (en) 2008-08-07
HUP1500188A2 (en) 2005-03-29
ZA200308340B (en) 2004-05-21
MEP42508A (en) 2011-02-10
HRP20030993A2 (en) 2005-08-31
ES2236590T3 (en) 2005-07-16
UA75659C2 (en) 2006-05-15

Similar Documents

Publication Publication Date Title
HRP20030993B1 (en) Inhalation capsules
HUP0300593A3 (en) Pharmaceutical formulations for dry powder inhalers in the form of hard-pellets
AU8464301A (en) De-agglomerator for breath-actuated dry powder inhaler
IL187278A0 (en) Inhalator capsules
MY137181A (en) Pulmonary administration of chemically modified insulin
HRP20041152B1 (en) Pharmaceutical formulations
JPS6471472A (en) Oral implement
SG167657A1 (en) Novel medicament compositions based on tiotropium salts and on salmeterol salts
EE04451B1 (en) Powder inhaler capsule for pharmaceutical formulations
WO2001049274A3 (en) Methods for pulmonary delivery of interleukin-2
EP1487417A4 (en) Dry powder medicament formulations
WO2002047668A3 (en) Novel medicament compositions based on anticholinesterase drugs and on ciclesonides
SE0103211D0 (en) New formulations and use thereof
HK1047019A1 (en) Ventilated filter cigarette.
ATE271852T1 (en) IMPROVED INHALATION PREPARATIONS
SE0200657D0 (en) Novel Formulation
IL177354A0 (en) Alpha-emitting hydroxyapatite particles
MD1473G2 (en) Antiherpetic remedy
CA2436537A1 (en) Pharmaceutical compositions comprising tiotropium salts and antihistamines

Legal Events

Date Code Title Description
A1OB Publication of a patent application
ARAI Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application
B1PR Patent granted
PPPN Proposal for the declaration of nullity of a patent
PPND Declaration of nullification in part
ZALP Appeal filed
ODRP Renewal fee for the maintenance of a patent

Payment date: 20190506

Year of fee payment: 18

ODRP Renewal fee for the maintenance of a patent

Payment date: 20200520

Year of fee payment: 19

ZALO Appeal rejected/withdrawn /refused
ODRP Renewal fee for the maintenance of a patent

Payment date: 20210517

Year of fee payment: 20

USP1 Administrative dispute
PB20 Patent expired after termination of 20 years

Effective date: 20220527

USP2 Decision of an administrative court