Nothing Special   »   [go: up one dir, main page]

HK1231521A1 - 癌症復發的可能性預測 - Google Patents

癌症復發的可能性預測

Info

Publication number
HK1231521A1
HK1231521A1 HK17105303.2A HK17105303A HK1231521A1 HK 1231521 A1 HK1231521 A1 HK 1231521A1 HK 17105303 A HK17105303 A HK 17105303A HK 1231521 A1 HK1231521 A1 HK 1231521A1
Authority
HK
Hong Kong
Prior art keywords
likelihood
prediction
cancer recurrence
recurrence
cancer
Prior art date
Application number
HK17105303.2A
Other languages
English (en)
Inventor
Joffre Baker
Steve Shak
John Bryant
Soonmyung Paik
Original Assignee
Genomic Health Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34519967&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1231521(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genomic Health Inc filed Critical Genomic Health Inc
Publication of HK1231521A1 publication Critical patent/HK1231521A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
HK17105303.2A 2003-06-24 2015-03-03 癌症復發的可能性預測 HK1231521A1 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US48233903P 2003-06-24 2003-06-24

Publications (1)

Publication Number Publication Date
HK1231521A1 true HK1231521A1 (zh) 2017-12-22

Family

ID=34519967

Family Applications (2)

Application Number Title Priority Date Filing Date
HK15102130.0A HK1201569A1 (zh) 2003-06-24 2015-03-03 癌症復發的可能性預測
HK17105303.2A HK1231521A1 (zh) 2003-06-24 2015-03-03 癌症復發的可能性預測

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK15102130.0A HK1201569A1 (zh) 2003-06-24 2015-03-03 癌症復發的可能性預測

Country Status (11)

Country Link
US (5) US7056674B2 (zh)
EP (4) EP3170906B1 (zh)
JP (1) JP4680898B2 (zh)
AU (2) AU2004283068B2 (zh)
CA (2) CA3061769C (zh)
DK (4) DK1641810T4 (zh)
ES (4) ES2787475T3 (zh)
HK (2) HK1201569A1 (zh)
HU (1) HUE050365T2 (zh)
PL (1) PL3470535T3 (zh)
WO (1) WO2005039382A2 (zh)

Families Citing this family (105)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030198972A1 (en) 2001-12-21 2003-10-23 Erlander Mark G. Grading of breast cancer
US7081340B2 (en) * 2002-03-13 2006-07-25 Genomic Health, Inc. Gene expression profiling in biopsied tumor tissues
US7537891B2 (en) * 2002-08-27 2009-05-26 Bristol-Myers Squibb Company Identification of polynucleotides for predicting activity of compounds that interact with and/or modulate protein tyrosine kinases and/or protein tyrosine kinase pathways in breast cells
US7504211B2 (en) * 2002-08-27 2009-03-17 Bristol-Myers Squibb Company Methods of using EPHA2 for predicting activity of compounds that interact with and/or modulate protein tyrosine kinases and/or protein tyrosine kinase pathways in breast cells
US20040231909A1 (en) * 2003-01-15 2004-11-25 Tai-Yang Luh Motorized vehicle having forward and backward differential structure
GB0307428D0 (en) 2003-03-31 2003-05-07 Medical Res Council Compartmentalised combinatorial chemistry
US20060078893A1 (en) 2004-10-12 2006-04-13 Medical Research Council Compartmentalised combinatorial chemistry by microfluidic control
GB0307403D0 (en) 2003-03-31 2003-05-07 Medical Res Council Selection by compartmentalised screening
WO2005039382A2 (en) 2003-06-24 2005-05-06 Genomic Health Prediction of likelihood of cancer recurrence
US9856533B2 (en) 2003-09-19 2018-01-02 Biotheranostics, Inc. Predicting breast cancer treatment outcome
US20050221339A1 (en) 2004-03-31 2005-10-06 Medical Research Council Harvard University Compartmentalised screening by microfluidic control
WO2005100606A2 (en) 2004-04-09 2005-10-27 Genomic Health, Inc. Gene expression markers for predicting response to chemotherapy
CA2575557A1 (en) * 2004-07-30 2006-02-09 Rosetta Inpharmatics Llc Prognosis of breast cancer patients
JP5028601B2 (ja) * 2004-08-10 2012-09-19 オンコセラピー・サイエンス株式会社 乳癌に関連する遺伝子およびポリペプチド
US7968287B2 (en) 2004-10-08 2011-06-28 Medical Research Council Harvard University In vitro evolution in microfluidic systems
US20060134663A1 (en) * 2004-11-03 2006-06-22 Paul Harkin Transcriptome microarray technology and methods of using the same
EP1836629B1 (en) * 2004-11-05 2020-03-04 Genomic Health, Inc. Predicting response to chemotherapy using gene expression markers
AU2005314127A1 (en) * 2004-12-07 2006-06-15 Genentech, Inc. Selecting patients for therapy with a HER inhibitor
US7595380B2 (en) * 2005-04-27 2009-09-29 Tripath Imaging, Inc. Monoclonal antibodies and methods for their use in the detection of cervical disease
US20080275652A1 (en) * 2005-05-13 2008-11-06 Universite Libre De Bruxelles Gene-based algorithmic cancer prognosis
EP1750131B1 (en) * 2005-08-01 2008-07-09 Sysmex Corporation Method for judging feature of malignant tumor
WO2007070621A2 (en) * 2005-12-13 2007-06-21 Children's Medical Center Corporation Prognosis indicators for solid human tumors
EP2363205A3 (en) 2006-01-11 2014-06-04 Raindance Technologies, Inc. Microfluidic Devices And Methods Of Use In The Formation And Control Of Nanoreactors
US9562837B2 (en) 2006-05-11 2017-02-07 Raindance Technologies, Inc. Systems for handling microfludic droplets
US9074242B2 (en) 2010-02-12 2015-07-07 Raindance Technologies, Inc. Digital analyte analysis
EP3031918B1 (en) 2006-05-11 2018-03-14 Raindance Technologies Inc. Microfluidic devices
MX2008014608A (es) 2006-05-18 2009-03-31 Molecular Profiling Inst Inc Sistema y metodo para determinar la intervencion medica individualizada para un estado de enfermedad.
US8768629B2 (en) 2009-02-11 2014-07-01 Caris Mpi, Inc. Molecular profiling of tumors
EP2077912B1 (en) 2006-08-07 2019-03-27 The President and Fellows of Harvard College Fluorocarbon emulsion stabilizing surfactants
US7615349B2 (en) * 2006-09-07 2009-11-10 H. Lee Moffitt Cancer Center And Research Institute, Inc. Melanoma gene signature
EP2081950B1 (en) * 2006-09-21 2013-03-20 Nuclea Biomarkers LLC Expression profiles associated with irinotecan treatment
SG142186A1 (en) * 2006-10-20 2008-05-28 Agency Science Tech & Res Breast tumour grading
US8772046B2 (en) 2007-02-06 2014-07-08 Brandeis University Manipulation of fluids and reactions in microfluidic systems
US8030060B2 (en) * 2007-03-22 2011-10-04 West Virginia University Gene signature for diagnosis and prognosis of breast cancer and ovarian cancer
US20090062144A1 (en) * 2007-04-03 2009-03-05 Nancy Lan Guo Gene signature for prognosis and diagnosis of lung cancer
US8592221B2 (en) 2007-04-19 2013-11-26 Brandeis University Manipulation of fluids, fluid components and reactions in microfluidic systems
JP2008278798A (ja) * 2007-05-10 2008-11-20 Tokyo Medical & Dental Univ 膀胱癌の検出方法
CA2694703A1 (en) 2007-08-16 2009-02-26 Aventis Inc. Gene expression markers of recurrence risk in cancer patients after chemotherapy
ES2618353T3 (es) * 2007-09-06 2017-06-21 Biotheranostics, Inc. Clasificación de tumores y pronóstico del cáncer de mama
WO2009048901A1 (en) * 2007-10-09 2009-04-16 University Of Washington Quantitative/semi-quantitative measurement of epor on cancer cells
EP2201138B1 (en) * 2007-10-16 2015-03-18 Ventana Medical Systems, Inc. Grading, staging, and prognosing cancer using osteopontin-c
KR100980004B1 (ko) 2008-04-21 2010-09-03 한국생명공학연구원 위암 진단 마커로서의 엠이엘케이
WO2009131365A2 (ko) * 2008-04-21 2009-10-29 한국생명공학연구원 위암 진단 마커로서의 ｃst1, ｄcc1, ifitm1 또는 ｍelk
US20090311702A1 (en) 2008-05-12 2009-12-17 Steve Shak Tests to predict responsiveness of cancer patients to chemotherapy treatment options
EP2315629B1 (en) 2008-07-18 2021-12-15 Bio-Rad Laboratories, Inc. Droplet libraries
US12038438B2 (en) 2008-07-18 2024-07-16 Bio-Rad Laboratories, Inc. Enzyme quantification
TWI466680B (zh) 2008-08-01 2015-01-01 Oncotherapy Science Inc Ｍｅｌｋ抗原決定位胜肽及含此胜肽的疫苗
US10359425B2 (en) * 2008-09-09 2019-07-23 Somalogic, Inc. Lung cancer biomarkers and uses thereof
US20100221752A2 (en) * 2008-10-06 2010-09-02 Somalogic, Inc. Ovarian Cancer Biomarkers and Uses Thereof
WO2010045463A2 (en) 2008-10-15 2010-04-22 Government Of The United States As Represented By The Secretary Of The Army Clinical decision model
GB2463401B (en) 2008-11-12 2014-01-29 Caris Life Sciences Luxembourg Holdings S A R L Characterizing prostate disorders by analysis of microvesicles
JP2012514474A (ja) * 2009-01-07 2012-06-28 ミリアド・ジェネティックス・インコーポレイテッド がんバイオマーカー
US20120041274A1 (en) 2010-01-07 2012-02-16 Myriad Genetics, Incorporated Cancer biomarkers
CA2753971C (en) * 2009-01-28 2018-10-02 Steven Buechler Accelerated progression relapse test
EP2411148B1 (en) 2009-03-23 2018-02-21 Raindance Technologies, Inc. Manipulation of microfluidic droplets
EP2486154B1 (en) * 2009-10-08 2017-03-01 Wake Forest University Health Sciences Diagnostic and prognostic markers for cancer
US10520500B2 (en) 2009-10-09 2019-12-31 Abdeslam El Harrak Labelled silica-based nanomaterial with enhanced properties and uses thereof
DE102010043541B4 (de) 2009-12-16 2012-01-26 Technische Universität Dresden Verfahren und Mittel zur Vorhersage der Überlebensdauer beim Pankreaskarzinom durch Analyse von Biomarkern
US10837883B2 (en) 2009-12-23 2020-11-17 Bio-Rad Laboratories, Inc. Microfluidic systems and methods for reducing the exchange of molecules between droplets
EP3178944B1 (en) 2010-01-11 2019-05-15 Genomic Health, Inc. Method to use gene expression to determine likelihood of clinical outcome of renal cancer
TWI485245B (zh) 2010-01-25 2015-05-21 Oncotherapy Science Inc 經修飾之ｍｅｌｋ胜肽及含此胜肽之疫苗
US10351905B2 (en) 2010-02-12 2019-07-16 Bio-Rad Laboratories, Inc. Digital analyte analysis
US9366632B2 (en) 2010-02-12 2016-06-14 Raindance Technologies, Inc. Digital analyte analysis
US9399797B2 (en) 2010-02-12 2016-07-26 Raindance Technologies, Inc. Digital analyte analysis
JP5808349B2 (ja) 2010-03-01 2015-11-10 カリス ライフ サイエンシズ スウィッツァーランド ホールディングスゲーエムベーハー セラノーシスのためのバイオマーカー
KR20130043104A (ko) 2010-04-06 2013-04-29 카리스 라이프 사이언스 룩셈부르크 홀딩스 질병용 순환 생물학적 지표들
EP2591126B1 (en) 2010-07-07 2020-12-30 Myriad Genetics, Inc. Gene signatures for cancer prognosis
CN104777313B (zh) 2010-07-09 2017-09-26 私募蛋白质体公司 肺癌生物标记及其用途
CA3081061C (en) 2010-07-27 2023-01-03 Genomic Health, Inc. Method for using expression of klk2 to determine prognosis of prostate cancer
US20120040861A1 (en) 2010-08-13 2012-02-16 Somalogic, Inc. Pancreatic Cancer Biomarkers and Uses Thereof
US9605319B2 (en) 2010-08-30 2017-03-28 Myriad Genetics, Inc. Gene signatures for cancer diagnosis and prognosis
EP3447155A1 (en) 2010-09-30 2019-02-27 Raindance Technologies, Inc. Sandwich assays in droplets
CN103998064A (zh) 2010-12-09 2014-08-20 生物诊断治疗公司 治疗后的乳腺癌预后
EP3412778A1 (en) 2011-02-11 2018-12-12 Raindance Technologies, Inc. Methods for forming mixed droplets
EP2675819B1 (en) 2011-02-18 2020-04-08 Bio-Rad Laboratories, Inc. Compositions and methods for molecular labeling
US8841071B2 (en) 2011-06-02 2014-09-23 Raindance Technologies, Inc. Sample multiplexing
EP2714970B1 (en) 2011-06-02 2017-04-19 Raindance Technologies, Inc. Enzyme quantification
CA2840946A1 (en) * 2011-06-22 2012-12-27 Oncocyte Corporation Methods and compositions for the treatment and diagnosis of cancer
US8658430B2 (en) 2011-07-20 2014-02-25 Raindance Technologies, Inc. Manipulating droplet size
WO2013023132A1 (en) 2011-08-10 2013-02-14 Wake Forest University Health Sciences Diagnostic and prognostic markers for cancer
AU2012301664A1 (en) * 2011-08-31 2014-02-27 Oncocyte Corporation Methods and compositions for the treatment and diagnosis of cancer
WO2013120089A1 (en) 2012-02-10 2013-08-15 Raindance Technologies, Inc. Molecular diagnostic screening assay
EP3524693A1 (en) 2012-04-30 2019-08-14 Raindance Technologies, Inc. Digital analyte analysis
US20130337444A1 (en) 2012-05-22 2013-12-19 Nanostring Technologies, Inc. NANO46 Genes and Methods to Predict Breast Cancer Outcome
EP4190918A1 (en) 2012-11-16 2023-06-07 Myriad Genetics, Inc. Gene signatures for cancer prognosis
WO2014113641A1 (en) 2013-01-18 2014-07-24 Kline Ellis Selective glycosidase regimen for immune programming and treatment of cancer
JP6576249B2 (ja) 2013-02-11 2019-09-18 インクロン， インコーポレイテッド 癌におけるクロマチン転写促進因子（ｆａｃｔ）の使用
WO2014172288A2 (en) 2013-04-19 2014-10-23 Raindance Technologies, Inc. Digital analyte analysis
ES2829415T3 (es) 2013-05-30 2021-05-31 Genomic Health Inc Algoritmo de perfil de expresión génica para calcular una puntuación de recurrencia para un paciente con cáncer de riñón
US11901041B2 (en) 2013-10-04 2024-02-13 Bio-Rad Laboratories, Inc. Digital analysis of nucleic acid modification
US9944977B2 (en) 2013-12-12 2018-04-17 Raindance Technologies, Inc. Distinguishing rare variations in a nucleic acid sequence from a sample
EP3090063B1 (en) 2013-12-31 2019-11-06 Bio-Rad Laboratories, Inc. Method for detection of latent retrovirus
EP3143160B1 (en) 2014-05-13 2019-11-06 Myriad Genetics, Inc. Gene signatures for cancer prognosis
US10557175B2 (en) 2014-09-19 2020-02-11 The Provost, Fellows, Scholars And Other Members Of Board Of Trinity College Dublin Method of predicting risk of recurrence of cancer
WO2016062892A1 (en) 2014-10-24 2016-04-28 Koninklijke Philips N.V. Medical prognosis and prediction of treatment response using multiple cellular signaling pathway activities
ES2838923T3 (es) 2014-10-24 2021-07-02 Koninklijke Philips Nv Pronóstico médico y predicción de la respuesta a tratamiento usando múltiples actividades de la ruta de señalización celular
EP3210142B1 (en) 2014-10-24 2020-09-16 Koninklijke Philips N.V. Assessment of tgf-cellular signaling pathway activity using mathematical modelling of target gene expression
CN108138237B (zh) 2015-08-14 2022-04-05 皇家飞利浦有限公司 使用靶基因表达的数学建模评估NFkB细胞信号传导途径活性
US10647981B1 (en) 2015-09-08 2020-05-12 Bio-Rad Laboratories, Inc. Nucleic acid library generation methods and compositions
IL259241B2 (en) 2015-11-13 2024-04-01 Biotheranostics Inc Combination of tumor characteristics with breast cancer index
US10998178B2 (en) 2017-08-28 2021-05-04 Purdue Research Foundation Systems and methods for sample analysis using swabs
EP3461916A1 (en) 2017-10-02 2019-04-03 Koninklijke Philips N.V. Assessment of jak-stat3 cellular signaling pathway activity using mathematical modelling of target gene expression
EP3461915A1 (en) 2017-10-02 2019-04-03 Koninklijke Philips N.V. Assessment of jak-stat1/2 cellular signaling pathway activity using mathematical modelling of target gene expression
US12027276B1 (en) 2017-10-27 2024-07-02 DecisionQ Corporation Methods, systems and devices for assessing wound healing
EP3502279A1 (en) 2017-12-20 2019-06-26 Koninklijke Philips N.V. Assessment of mapk-ap 1 cellular signaling pathway activity using mathematical modelling of target gene expression

Family Cites Families (95)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE56509B1 (en) 1982-11-04 1991-08-28 Univ California Methods for oncogenic detection
USRE35491E (en) 1982-11-04 1997-04-08 The Regents Of The University Of California Methods and compositions for detecting human tumors
US4699877A (en) 1982-11-04 1987-10-13 The Regents Of The University Of California Methods and compositions for detecting human tumors
US7838216B1 (en) 1986-03-05 2010-11-23 The United States Of America, As Represented By The Department Of Health And Human Services Human gene related to but distinct from EGF receptor gene
US5015568A (en) 1986-07-09 1991-05-14 The Wistar Institute Diagnostic methods for detecting lymphomas in humans
US5202429A (en) 1986-07-09 1993-04-13 The Wistar Institute DNA molecules having human BCL-2 gene sequences
US4968603A (en) 1986-12-31 1990-11-06 The Regents Of The University Of California Determination of status in neoplastic disease
US5831066A (en) 1988-12-22 1998-11-03 The Trustees Of The University Of Pennsylvania Regulation of bcl-2 gene expression
US5858678A (en) 1994-08-02 1999-01-12 St. Louis University Apoptosis-regulating proteins
US5830753A (en) 1994-09-30 1998-11-03 Ludwig Institute For Cancer Research Isolated nucleic acid molecules coding for tumor rejection antigen precursor dage and uses thereof.
US6716575B2 (en) 1995-12-18 2004-04-06 Sugen, Inc. Diagnosis and treatment of AUR1 and/or AUR2 related disorders
WO1997022702A1 (en) 1995-12-18 1997-06-26 Sugen, Inc. Diagnosis and treatment of aur-1 and/or aur-2 related disorders
US5670325A (en) 1996-08-14 1997-09-23 Exact Laboratories, Inc. Method for the detection of clonal populations of transformed cells in a genomically heterogeneous cellular sample
US5962313A (en) 1996-01-18 1999-10-05 Avigen, Inc. Adeno-associated virus vectors comprising a gene encoding a lyosomal enzyme
US5741650A (en) 1996-01-30 1998-04-21 Exact Laboratories, Inc. Methods for detecting colon cancer from stool samples
US5821082A (en) 1996-05-23 1998-10-13 St. Louis University Health Sciences Center Anti-proliferation domain of a human Bcl-2 and DNA encoding the same
US6143529A (en) 1996-08-14 2000-11-07 Exact Laboratories, Inc. Methods for improving sensitivity and specificity of screening assays
US6100029A (en) 1996-08-14 2000-08-08 Exact Laboratories, Inc. Methods for the detection of chromosomal aberrations
US5928870A (en) 1997-06-16 1999-07-27 Exact Laboratories, Inc. Methods for the detection of loss of heterozygosity
US5952178A (en) 1996-08-14 1999-09-14 Exact Laboratories Methods for disease diagnosis from stool samples
US6203993B1 (en) 1996-08-14 2001-03-20 Exact Science Corp. Methods for the detection of nucleic acids
US6020137A (en) 1996-08-14 2000-02-01 Exact Laboratories, Inc. Methods for the detection of loss of heterozygosity
US6146828A (en) 1996-08-14 2000-11-14 Exact Laboratories, Inc. Methods for detecting differences in RNA expression levels and uses therefor
US5861278A (en) 1996-11-01 1999-01-19 Genetics Institute, Inc. HNF3δ compositions
DE69739105D1 (de) 1996-11-20 2008-12-24 Univ Yale Survivin, ein protein das zelluläre apoptosis hemmt, und dessen modulation
US5846723A (en) * 1996-12-20 1998-12-08 Geron Corporation Methods for detecting the RNA component of telomerase
US5830665A (en) 1997-03-03 1998-11-03 Exact Laboratories, Inc. Contiguous genomic sequence scanning
US6033893A (en) 1997-06-26 2000-03-07 Incyte Pharmaceuticals, Inc. Human cathepsin
WO1999002714A1 (en) 1997-07-07 1999-01-21 Abbott Laboratories Reagents and methods useful for detecting diseases of the breast
AUPO938897A0 (en) * 1997-09-23 1997-10-16 Garvan Institute Of Medical Research A potential effector for the grb7 family of signalling proteins
US6358682B1 (en) 1998-01-26 2002-03-19 Ventana Medical Systems, Inc. Method and kit for the prognostication of breast cancer
US6020135A (en) 1998-03-27 2000-02-01 Affymetrix, Inc. P53-regulated genes
EP1084273A1 (en) 1998-06-06 2001-03-21 Genostic Pharma Limited Probes used for genetic profiling
US6696558B2 (en) 1998-09-09 2004-02-24 The Burnham Institute Bag proteins and nucleic acid molecules encoding them
WO2000050595A2 (en) 1999-02-25 2000-08-31 Ivan Gout Nucleic acid molecules associated with melanoma and thyroid tumors
US20020039764A1 (en) 1999-03-12 2002-04-04 Rosen Craig A. Nucleic, acids, proteins, and antibodies
AU3395900A (en) 1999-03-12 2000-10-04 Human Genome Sciences, Inc. Human lung cancer associated gene sequences and polypeptides
US6692916B2 (en) 1999-06-28 2004-02-17 Source Precision Medicine, Inc. Systems and methods for characterizing a biological condition or agent using precision gene expression profiles
US6960439B2 (en) 1999-06-28 2005-11-01 Source Precision Medicine, Inc. Identification, monitoring and treatment of disease and characterization of biological condition using gene expression profiles
AU5789500A (en) * 1999-07-09 2001-01-30 Burnham Institute, The A method for determining the prognosis of cancer patients by measuring levels ofbag expression
US6326148B1 (en) 1999-07-12 2001-12-04 The Regents Of The University Of California Detection of copy number changes in colon cancer
US6710170B2 (en) 1999-09-10 2004-03-23 Corixa Corporation Compositions and methods for the therapy and diagnosis of ovarian cancer
US6271002B1 (en) 1999-10-04 2001-08-07 Rosetta Inpharmatics, Inc. RNA amplification method
AU777096B2 (en) 1999-10-06 2004-09-30 Regents Of The University Of California, The Differentially expressed genes associated with Her-2/neu overexpression
EP1661996A1 (en) 1999-12-01 2006-05-31 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US6750013B2 (en) 1999-12-02 2004-06-15 Protein Design Labs, Inc. Methods for detection and diagnosing of breast cancer
US6248535B1 (en) * 1999-12-20 2001-06-19 University Of Southern California Method for isolation of RNA from formalin-fixed paraffin-embedded tissue specimens
WO2001051661A2 (en) 2000-01-13 2001-07-19 Amsterdam Support Diagnostics B.V. A universal nucleic acid amplification system for nucleic acids in a sample
US6322986B1 (en) 2000-01-18 2001-11-27 Albany Medical College Method for colorectal cancer prognosis and treatment selection
EP1257664A4 (en) 2000-01-28 2006-04-05 Althea Technologies Inc METHOD FOR THE ANALYSIS OF GENE EXPRESSION
WO2001054733A1 (en) 2000-01-31 2001-08-02 Human Genome Sciences, Inc. Nucleic acids, proteins and antibodies
WO2001070979A2 (en) 2000-03-21 2001-09-27 Millennium Pharmaceuticals, Inc. Genes, compositions, kits, and method for identification, assessment, prevention and therapy of ovarian cancer
WO2001075159A2 (en) 2000-03-31 2001-10-11 Sir Mortimer B. Davis Jewish General Hospital Microchip arrays of regulatory genes
AU2001266787A1 (en) 2000-06-07 2002-01-08 Human Genome Sciences, Inc. Nucleic acids, proteins, and antibodies
US6974667B2 (en) 2000-06-14 2005-12-13 Gene Logic, Inc. Gene expression profiles in liver cancer
WO2001098359A2 (en) * 2000-06-21 2001-12-27 Wyeth Cyr61 as a target for treatment and diagnosis of breast cancer
EP1167975B1 (en) * 2000-06-22 2009-10-07 Universite Paris Descartes Compositions and methods for detecting, treating or predicting the response of breast tumor cells to endocrine therapy
MXPA03000575A (es) 2000-07-21 2004-12-13 Global Genomics Ab Metodos para analisis e identificacion de genes transcritos e impresion dactilar.
AU2001277202A1 (en) 2000-07-26 2002-02-05 Applied Genomics, Inc. Bstp-ras/rerg protein and related reagents and methods of use thereof
WO2002008261A2 (en) 2000-07-26 2002-01-31 Stanford University Bstp-trans protein and related reagents and methods of use thereof
AU2001278011A1 (en) 2000-07-26 2002-02-05 Applied Genomics, Inc. Bstp-ecg1 protein and related reagents and methods of use thereof
WO2002010436A2 (en) * 2000-07-28 2002-02-07 The Brigham And Women's Hospital, Inc. Prognostic classification of breast cancer
US7795232B1 (en) 2000-08-25 2010-09-14 Genta Incorporated Methods of treatment of a bcl-2 disorder using bcl-2 antisense oligomers
US20020156263A1 (en) * 2000-10-05 2002-10-24 Huei-Mei Chen Genes expressed in breast cancer
FR2815025B1 (fr) 2000-10-06 2003-08-29 Eurodim Sa Systeme de transfert d'un produit fluide, notamment du gaz naturel liquefie a temperature cryogenique, entre un navire de transport et une installation terrestre de traitement et de stockage de ce produit
WO2002036142A2 (en) * 2000-11-03 2002-05-10 University Of Vermont And State Agricultural College Compositions for inhibiting grb7
US6602670B2 (en) 2000-12-01 2003-08-05 Response Genetics, Inc. Method of determining a chemotherapeutic regimen based on ERCC1 expression
US6582919B2 (en) 2001-06-11 2003-06-24 Response Genetics, Inc. Method of determining epidermal growth factor receptor and HER2-neu gene expression and correlation of levels thereof with survival rates
JP2004537261A (ja) * 2000-12-08 2004-12-16 イプソゲン 候補遺伝子のアレイを用いた原発性乳がんの遺伝子発現プロファイリング
AU2002255478A1 (en) 2001-01-10 2002-09-12 Pe Corporation (Ny) Kits, such as nucleic acid arrays, comprising a majority of human exons or transcripts, for detecting expression and other uses thereof
EP1350114A2 (en) 2001-01-12 2003-10-08 Yale University Detection of survivin in the biological fluids of cancer patients
US7776518B2 (en) 2001-01-12 2010-08-17 Yale University Detection of survivin in the biological fluids of cancer patients
WO2002059377A2 (en) 2001-01-24 2002-08-01 Protein Design Labs Methods of diagnosis of breast cancer, compositions and methods of screening for modulators of breast cancer
US20070015148A1 (en) 2001-01-25 2007-01-18 Orr Michael S Gene expression profiles in breast tissue
CA2440753A1 (en) 2001-03-12 2002-09-19 Monogen, Inc Cell-based detection and differentiation of disease states
WO2002072828A1 (fr) * 2001-03-14 2002-09-19 Dna Chip Research Inc. Procede permettant de prevoir un cancer
WO2002084560A1 (en) * 2001-04-06 2002-10-24 Florence Comite System and method for delivering integrated health care
AU2002316251A1 (en) 2001-06-18 2003-01-02 Rosetta Inpharmatics, Inc. Diagnosis and prognosis of breast cancer patients
WO2003011897A1 (en) 2001-07-27 2003-02-13 The Regents Of The University Of California Modulation of heregulin and her3 interaction
EP1444361A4 (en) 2001-09-28 2006-12-27 Whitehead Biomedical Inst CLASSIFICATION OF LUNG CARCINOMAS BY GENE EXPRESSION ANALYSIS
CN1612936A (zh) 2001-11-09 2005-05-04 苏尔斯精细医药公司 利用基因表达分布图识别、监控和治疗疾病以及鉴定生物学状态
US20030198972A1 (en) 2001-12-21 2003-10-23 Erlander Mark G. Grading of breast cancer
US20050216961A1 (en) 2002-03-28 2005-09-29 Delaney Allen D Cancer associated protein kinases and their uses
EP1900827A3 (en) 2002-05-21 2008-04-16 Bayer HealthCare AG Methods and compositions for the prediction, diagnosis, prognosis, prevention and treatment of malignant neoplasia
US20040231909A1 (en) * 2003-01-15 2004-11-25 Tai-Yang Luh Motorized vehicle having forward and backward differential structure
PT1597391E (pt) 2003-02-20 2008-12-19 Genomic Health Inc Utilização de arn intrónico para medir a expressão genética
US20050064455A1 (en) * 2003-05-28 2005-03-24 Baker Joffre B. Gene expression markers for predicting response to chemotherapy
WO2005039382A2 (en) * 2003-06-24 2005-05-06 Genomic Health Prediction of likelihood of cancer recurrence
CA2531967C (en) * 2003-07-10 2013-07-16 Genomic Health, Inc. Expression profile algorithm and test for cancer prognosis
WO2005100606A2 (en) 2004-04-09 2005-10-27 Genomic Health, Inc. Gene expression markers for predicting response to chemotherapy
US7622251B2 (en) * 2004-11-05 2009-11-24 Genomic Health, Inc. Molecular indicators of breast cancer prognosis and prediction of treatment response
EP1836629B1 (en) * 2004-11-05 2020-03-04 Genomic Health, Inc. Predicting response to chemotherapy using gene expression markers
US20070105133A1 (en) * 2005-06-13 2007-05-10 The Regents Of The University Of Michigan Compositions and methods for treating and diagnosing cancer
CA2694703A1 (en) 2007-08-16 2009-02-26 Aventis Inc. Gene expression markers of recurrence risk in cancer patients after chemotherapy
US20090311702A1 (en) * 2008-05-12 2009-12-17 Steve Shak Tests to predict responsiveness of cancer patients to chemotherapy treatment options

Also Published As

Publication number Publication date
EP3170906A1 (en) 2017-05-24
CA2530738C (en) 2020-01-21
US10619215B2 (en) 2020-04-14
ES2787475T3 (es) 2020-10-16
EP3170906B1 (en) 2018-08-22
AU2010202424A1 (en) 2010-07-01
EP2775000A1 (en) 2014-09-10
EP1641810A2 (en) 2006-04-05
WO2005039382A3 (en) 2006-01-12
EP1641810B1 (en) 2014-05-14
DK3170906T3 (en) 2018-11-05
AU2010202424B2 (en) 2012-12-06
ES2609234T3 (es) 2017-04-19
HUE050365T2 (hu) 2022-09-28
JP2007521005A (ja) 2007-08-02
EP2775000B1 (en) 2016-11-09
ES2488845T5 (es) 2017-07-11
DK3470535T3 (da) 2020-06-29
JP4680898B2 (ja) 2011-05-11
ES2690168T3 (es) 2018-11-19
US20050079518A1 (en) 2005-04-14
US20180051348A1 (en) 2018-02-22
ES2488845T3 (es) 2014-08-29
PL3470535T3 (pl) 2020-08-24
US20060286565A1 (en) 2006-12-21
US7056674B2 (en) 2006-06-06
HK1201569A1 (zh) 2015-09-04
EP1641810A4 (en) 2009-03-25
US20200299781A1 (en) 2020-09-24
EP3470535B1 (en) 2020-04-01
WO2005039382A2 (en) 2005-05-06
CA2530738A1 (en) 2005-05-06
DK1641810T3 (da) 2014-08-04
EP1641810B2 (en) 2017-04-19
CA3061769C (en) 2021-10-26
CA3061769A1 (en) 2005-05-06
AU2004283068A1 (en) 2005-05-06
AU2004283068B2 (en) 2010-03-18
EP3470535A1 (en) 2019-04-17
US7723033B2 (en) 2010-05-25
DK1641810T4 (en) 2017-07-03
DK2775000T3 (en) 2017-02-13
US20100267032A1 (en) 2010-10-21

Similar Documents

Publication Publication Date Title
HK1201569A1 (zh) 癌症復發的可能性預測
EP1697497A4 (en) LIVER CANCER BIOMARKERS
EP1667680A4 (en) COMBINED METHODS OF TREATING CANCER
AU2003294205A8 (en) Prostate cancer biomarkers
EP1613308A4 (en) CANCER TREATMENT METHODS
AU2003253860A8 (en) Expression profile of lung cancer
TWI317753B (en) Cmp of noble metals
GB0228900D0 (en) Cancer Immunotherapy
EP1496923A4 (en) IMMUNOTHERAPY AGAINST CANCER
AU2003279101A8 (en) Methylation profile of cancer
EP1625853A4 (en) APOPTOSIS INDUCER FOR CANCER CELL
EP1685423A4 (en) INDIVIDUAL RADIOBALISE OF REPERAGE
AU2003278211A8 (en) Methods for detection of genetic alterations associated with cancer
GB0226595D0 (en) Cancer therapy determination
GB0329416D0 (en) Treatment of cancer
EP1693069A4 (en) MEANS FOR THE TREATMENT OF SOLID TUMORS
AU2003903274A0 (en) Method of assessing cancer risk
GB0200110D0 (en) Cancer detection
EP1616190A4 (en) DIAGNOSIS OF CANCER AT AN ADVANCED STAGE
GB0328690D0 (en) Tumour suppressor protein
EP1595546A4 (en) REMEDIES AGAINST CANCER
GB0329820D0 (en) Anti cancer compounds
GB0410379D0 (en) Treatment of cancer
GB0302825D0 (en) Age determination of death
GB0423273D0 (en) Treatment of cancer

Legal Events

Date Code Title Description
PE Patent expired

Effective date: 20240616