HK1223624A1 - 替諾福韋的固體形式 - Google Patents
替諾福韋的固體形式Info
- Publication number
- HK1223624A1 HK1223624A1 HK16111943.7A HK16111943A HK1223624A1 HK 1223624 A1 HK1223624 A1 HK 1223624A1 HK 16111943 A HK16111943 A HK 16111943A HK 1223624 A1 HK1223624 A1 HK 1223624A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- tenofovir
- solid forms
- solid
- forms
- Prior art date
Links
- 239000007787 solid Substances 0.000 title 1
- 229960004556 tenofovir Drugs 0.000 title 1
- VCMJCVGFSROFHV-WZGZYPNHSA-N tenofovir disoproxil fumarate Chemical compound OC(=O)\C=C\C(O)=O.N1=CN=C2N(C[C@@H](C)OCP(=O)(OCOC(=O)OC(C)C)OCOC(=O)OC(C)C)C=NC2=C1N VCMJCVGFSROFHV-WZGZYPNHSA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
- C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Polyesters Or Polycarbonates (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461927617P | 2014-01-15 | 2014-01-15 | |
| PCT/US2015/010831 WO2015108780A1 (en) | 2014-01-15 | 2015-01-09 | Solid forms of tenofovir |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1223624A1 true HK1223624A1 (zh) | 2017-08-04 |
Family
ID=52434978
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK16111943.7A HK1223624A1 (zh) | 2014-01-15 | 2016-10-17 | 替諾福韋的固體形式 |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US9487546B2 (zh) |
| EP (1) | EP3094637B1 (zh) |
| JP (2) | JP2017507914A (zh) |
| KR (1) | KR20160099655A (zh) |
| CN (1) | CN105960409A (zh) |
| AR (1) | AR099082A1 (zh) |
| AU (1) | AU2015206758B2 (zh) |
| CA (1) | CA2935965A1 (zh) |
| EA (1) | EA031174B1 (zh) |
| ES (1) | ES2762783T3 (zh) |
| HK (1) | HK1223624A1 (zh) |
| IL (1) | IL246569A0 (zh) |
| MX (1) | MX2016008884A (zh) |
| NZ (1) | NZ721832A (zh) |
| PL (1) | PL3094637T3 (zh) |
| PT (1) | PT3094637T (zh) |
| SG (1) | SG11201605415RA (zh) |
| SI (1) | SI3094637T1 (zh) |
| TW (1) | TWI660965B (zh) |
| WO (1) | WO2015108780A1 (zh) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7381190B2 (ja) | 2014-12-26 | 2023-11-15 | エモリー・ユニバーシテイ | Ｎ４－ヒドロキシシチジン及び誘導体並びにそれに関連する抗ウイルス用途 |
| CN106380484A (zh) * | 2016-08-29 | 2017-02-08 | 杭州百诚医药科技股份有限公司 | 一种替诺福韦艾拉酚胺的新晶型及其制备方法 |
| CN118477088A (zh) | 2017-12-07 | 2024-08-13 | 埃默里大学 | N4-羟基胞苷及衍生物和与其相关的抗病毒用途 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6057305A (en) | 1992-08-05 | 2000-05-02 | Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic | Antiretroviral enantiomeric nucleotide analogs |
| JP4033494B2 (ja) * | 1996-07-26 | 2008-01-16 | ギリヤド サイエンシーズ， インコーポレイテッド | ヌクレオチドアナログ |
| US5922695A (en) | 1996-07-26 | 1999-07-13 | Gilead Sciences, Inc. | Antiviral phosphonomethyoxy nucleotide analogs having increased oral bioavarilability |
| US5935946A (en) | 1997-07-25 | 1999-08-10 | Gilead Sciences, Inc. | Nucleotide analog composition and synthesis method |
| EP2682397B1 (en) * | 2000-07-21 | 2017-04-19 | Gilead Sciences, Inc. | Prodrugs of phosphonate nucleotide analogues and methods for selecting and making same |
| AP2089A (en) | 2003-01-14 | 2010-01-11 | Gilead Sciences Inc | Compositions and methods for combination antiviraltherapy |
| WO2008007392A2 (en) * | 2006-07-12 | 2008-01-17 | Matrix Laboratories Limited | Process for the preparation of tenofovir |
| JP5562337B2 (ja) * | 2008-12-17 | 2014-07-30 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ドネペジルの多形結晶及びその製造方法 |
| ZA201103820B (en) * | 2010-12-13 | 2012-01-25 | Laurus Labs Private Ltd | Process for the preparation of tenofovir |
| BR112014003420B1 (pt) * | 2011-08-16 | 2021-07-20 | Gilead Sciences, Inc | Hemifumarato de tenofovir alafenamida. composição, seus métodos de preparação e uso |
| CN117343101A (zh) | 2011-10-07 | 2024-01-05 | 吉利德科学公司 | 制备抗病毒核苷酸类似物的方法 |
| ES2627348T3 (es) * | 2011-11-16 | 2017-07-27 | Laurus Labs Private Limited | Proceso para la preparación de Tenofovir |
| CN103374038B (zh) * | 2012-04-11 | 2016-04-13 | 广州白云山医药集团股份有限公司白云山制药总厂 | 一种抗病毒药物的制备方法 |
| CN102899367B (zh) * | 2012-09-24 | 2014-04-30 | 常州大学 | 一种生物法和化学法结合合成泰诺福韦的方法 |
| CN103641758B (zh) * | 2013-11-19 | 2016-03-30 | 重庆紫光化工股份有限公司 | 廉价的高纯度的d,l-蛋氨酸的制备方法 |
-
2014
- 2014-12-12 TW TW103143442A patent/TWI660965B/zh active
-
2015
- 2015-01-09 EP EP15701877.1A patent/EP3094637B1/en active Active
- 2015-01-09 CA CA2935965A patent/CA2935965A1/en not_active Abandoned
- 2015-01-09 KR KR1020167019027A patent/KR20160099655A/ko active Search and Examination
- 2015-01-09 EA EA201691203A patent/EA031174B1/ru not_active IP Right Cessation
- 2015-01-09 ES ES15701877T patent/ES2762783T3/es active Active
- 2015-01-09 NZ NZ721832A patent/NZ721832A/en unknown
- 2015-01-09 AU AU2015206758A patent/AU2015206758B2/en active Active
- 2015-01-09 CN CN201580004462.3A patent/CN105960409A/zh active Pending
- 2015-01-09 PL PL15701877T patent/PL3094637T3/pl unknown
- 2015-01-09 SG SG11201605415RA patent/SG11201605415RA/en unknown
- 2015-01-09 US US14/593,556 patent/US9487546B2/en active Active
- 2015-01-09 MX MX2016008884A patent/MX2016008884A/es unknown
- 2015-01-09 PT PT157018771T patent/PT3094637T/pt unknown
- 2015-01-09 WO PCT/US2015/010831 patent/WO2015108780A1/en active Application Filing
- 2015-01-09 JP JP2016545902A patent/JP2017507914A/ja not_active Withdrawn
- 2015-01-09 SI SI201530958T patent/SI3094637T1/sl unknown
- 2015-01-13 AR ARP150100078A patent/AR099082A1/es unknown
-
2016
- 2016-07-03 IL IL246569A patent/IL246569A0/en unknown
- 2016-10-05 US US15/285,924 patent/US20170056424A1/en not_active Abandoned
- 2016-10-17 HK HK16111943.7A patent/HK1223624A1/zh unknown
-
2017
- 2017-11-29 JP JP2017228998A patent/JP2018030884A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AR099082A1 (es) | 2016-06-29 |
| WO2015108780A1 (en) | 2015-07-23 |
| US20170056424A1 (en) | 2017-03-02 |
| AU2015206758A1 (en) | 2016-07-21 |
| JP2018030884A (ja) | 2018-03-01 |
| PT3094637T (pt) | 2019-12-12 |
| CN105960409A (zh) | 2016-09-21 |
| JP2017507914A (ja) | 2017-03-23 |
| KR20160099655A (ko) | 2016-08-22 |
| EA201691203A1 (ru) | 2016-12-30 |
| ES2762783T3 (es) | 2020-05-25 |
| CA2935965A1 (en) | 2015-07-23 |
| US9487546B2 (en) | 2016-11-08 |
| PL3094637T3 (pl) | 2020-04-30 |
| MX2016008884A (es) | 2016-09-16 |
| TW201609780A (zh) | 2016-03-16 |
| SI3094637T1 (sl) | 2019-12-31 |
| US20150197535A1 (en) | 2015-07-16 |
| EP3094637A1 (en) | 2016-11-23 |
| SG11201605415RA (en) | 2016-07-28 |
| NZ721832A (en) | 2017-09-29 |
| EP3094637B1 (en) | 2019-10-16 |
| IL246569A0 (en) | 2016-08-31 |
| AU2015206758B2 (en) | 2017-11-30 |
| EA031174B1 (ru) | 2018-11-30 |
| TWI660965B (zh) | 2019-06-01 |
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