HK1222207A1 - 通過甲基化標記物來診斷癌症 - Google Patents
通過甲基化標記物來診斷癌症Info
- Publication number
- HK1222207A1 HK1222207A1 HK16110261.3A HK16110261A HK1222207A1 HK 1222207 A1 HK1222207 A1 HK 1222207A1 HK 16110261 A HK16110261 A HK 16110261A HK 1222207 A1 HK1222207 A1 HK 1222207A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- diagnosis
- cancer
- methylation marker
- methylation
- marker
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/154—Methylation markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Pathology (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2010904116A AU2010904116A0 (en) | 2010-09-13 | Diagnostic method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1222207A1 true HK1222207A1 (zh) | 2017-06-23 |
Family
ID=45830862
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK16110262.2A HK1222208A1 (zh) | 2010-09-13 | 2016-08-29 | 通過甲基化標記物來診斷癌症 |
| HK16110261.3A HK1222207A1 (zh) | 2010-09-13 | 2016-08-29 | 通過甲基化標記物來診斷癌症 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK16110262.2A HK1222208A1 (zh) | 2010-09-13 | 2016-08-29 | 通過甲基化標記物來診斷癌症 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20130338020A1 (zh) |
| EP (4) | EP3034629B1 (zh) |
| JP (6) | JP2013545437A (zh) |
| CN (2) | CN103314114B (zh) |
| AU (2) | AU2011301770B2 (zh) |
| BR (2) | BR112013005929B1 (zh) |
| CA (3) | CA2812115C (zh) |
| DK (4) | DK2616556T3 (zh) |
| ES (3) | ES2715226T3 (zh) |
| HK (2) | HK1222208A1 (zh) |
| NZ (1) | NZ608153A (zh) |
| WO (1) | WO2012034170A1 (zh) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012054975A1 (en) | 2010-10-28 | 2012-05-03 | Clinical Genomics Pty. Ltd. | Method of microvesicle enrichment |
| DK3594366T3 (da) * | 2012-05-11 | 2021-09-13 | Clinical Genomics Pty Ltd | Diagnostisk genmarkørpanel |
| EP4116437A1 (en) * | 2012-05-18 | 2023-01-11 | Clinical Genomics Pty. Ltd. | A method of screening for colorectal cancer |
| EP2698436A1 (en) * | 2012-08-14 | 2014-02-19 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Colorectal cancer markers |
| AU2013350330B2 (en) * | 2012-11-26 | 2019-06-06 | Clinical Genomics Pty Ltd | A method of detecting methylation |
| JP2016201999A (ja) * | 2013-08-26 | 2016-12-08 | 北海道公立大学法人 札幌医科大学 | 大腸癌を検出する方法 |
| US10301680B2 (en) * | 2014-03-31 | 2019-05-28 | Mayo Foundation For Medical Education And Research | Detecting colorectal neoplasm |
| KR102461235B1 (ko) * | 2014-06-04 | 2022-10-28 | 퀘스트 다이어그노스틱스 인베스트먼츠 인코포레이티드 | 결장직장암에 대한 메틸화된 마커 |
| WO2017040491A1 (en) | 2015-08-31 | 2017-03-09 | The United States Of America As Represented By The Secretary Of The Army | Methods for molecularly characterizing cervical cell samples |
| EP3845668A1 (en) * | 2015-10-30 | 2021-07-07 | New England Biolabs, Inc. | Compositions and methods for determining modified cytosines by sequencing |
| CN105543354B (zh) | 2015-12-31 | 2019-07-26 | 广州市康立明生物科技有限责任公司 | 一种肿瘤分子检测/诊断试剂 |
| CN106048091A (zh) * | 2016-07-28 | 2016-10-26 | 海南国际旅行卫生保健中心 | 检测登革病毒成熟miRNA的成套引物与方法 |
| EP3612627A4 (en) * | 2017-04-19 | 2020-12-30 | Singlera Genomics, Inc. | COMPOSITIONS AND METHODS FOR DETECTION OF GENOMIC VARIANCE AND OF DNA METHYLATION STATUS |
| IT201700072650A1 (it) * | 2017-06-28 | 2018-12-28 | Univ Degli Studi Cagliari | Metodo per rilevare e/o per la prognosi di neoplasie del colon-retto |
| JP2020527340A (ja) * | 2017-06-30 | 2020-09-10 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | セルフリーｄｎａ中のｄｎａメチル化を評価するための方法およびシステム |
| CN107858430B (zh) * | 2017-11-20 | 2019-01-04 | 武汉迈特维尔生物科技有限公司 | 一种用于诊断预示Her-2过表达型乳腺癌骨转移的基因诊断试剂盒 |
| CN110511998A (zh) * | 2018-05-22 | 2019-11-29 | 广州市康立明生物科技有限责任公司 | 肿瘤标志物、甲基化试剂、试剂盒及其应用 |
| CN110511997A (zh) * | 2018-05-22 | 2019-11-29 | 广州市康立明生物科技有限责任公司 | 肿瘤标志物、甲基化试剂、试剂盒及其应用 |
| CN110512001A (zh) * | 2018-05-22 | 2019-11-29 | 广州市康立明生物科技有限责任公司 | 肿瘤标志物、甲基化试剂、试剂盒及其应用 |
| CN110511999A (zh) * | 2018-05-22 | 2019-11-29 | 广州市康立明生物科技有限责任公司 | 肿瘤标志物、甲基化试剂、试剂盒及其应用 |
| CN108753963A (zh) * | 2018-06-01 | 2018-11-06 | 安徽达健医学科技有限公司 | 一种检测粪便脱落细胞dna甲基化状态用于分析大肠癌的试剂盒 |
| CN111363814B (zh) * | 2018-12-25 | 2023-12-19 | 广州康立明生物科技股份有限公司 | 基于dmrta2和foxd3基因的肺癌诊断试剂及试剂盒 |
| CN111363812B (zh) * | 2018-12-25 | 2023-12-19 | 广州康立明生物科技股份有限公司 | 基于dmrta2基因的肺癌诊断剂及试剂盒 |
| CN111363811B (zh) * | 2018-12-25 | 2024-02-02 | 广州康立明生物科技股份有限公司 | 基于foxd3基因的肺癌诊断剂及试剂盒 |
| CN109371138B (zh) * | 2018-12-29 | 2022-10-25 | 上海奕谱生物科技有限公司 | 基于甲基化修饰的肿瘤标记物stamp-ep4 |
| CN111662978B (zh) * | 2019-03-08 | 2021-11-16 | 北京大学 | 结直肠癌的dna甲基化标志物以及利用其检测结直肠癌的方法和试剂盒 |
| CN109971860B (zh) * | 2019-04-30 | 2022-10-11 | 上海奕谱生物科技有限公司 | 基于甲基化修饰的肿瘤标记物stamp-ep8及其应用 |
| CN110055330B (zh) * | 2019-04-30 | 2022-10-11 | 上海奕谱生物科技有限公司 | 基于甲基化修饰的肿瘤标记物stamp-ep9及其应用 |
| US11396679B2 (en) * | 2019-05-31 | 2022-07-26 | Universal Diagnostics, S.L. | Detection of colorectal cancer |
| US11001898B2 (en) | 2019-05-31 | 2021-05-11 | Universal Diagnostics, S.L. | Detection of colorectal cancer |
| CN110317871B (zh) * | 2019-07-11 | 2022-06-07 | 广州康立明生物科技股份有限公司 | 一种基因标志物组合及其应用 |
| CN110343764B (zh) * | 2019-07-22 | 2020-05-26 | 武汉艾米森生命科技有限公司 | 检测结直肠癌相关基因甲基化的检测试剂的应用和试剂盒 |
| US11427874B1 (en) | 2019-08-26 | 2022-08-30 | Epi One Inc. | Methods and systems for detection of prostate cancer by DNA methylation analysis |
| CN110699437B (zh) * | 2019-11-11 | 2023-06-20 | 益善生物技术股份有限公司 | 人sdc2基因甲基化检测试剂盒 |
| US11898199B2 (en) | 2019-11-11 | 2024-02-13 | Universal Diagnostics, S.A. | Detection of colorectal cancer and/or advanced adenomas |
| AU2021238717A1 (en) * | 2020-03-20 | 2022-08-25 | Singlera Health Technologies (Shanghai) Ltd. | Methods and kits for screening colorectal neoplasm |
| CN113930499B (zh) * | 2020-06-29 | 2023-09-22 | 武汉艾米森生命科技有限公司 | 检测基因甲基化的试剂的应用以及结直肠癌诊断或辅助诊断试剂盒 |
| EP4150121A1 (en) * | 2020-06-30 | 2023-03-22 | Universal Diagnostics, S.A. | Systems and methods for detection of multiple cancer types |
| US20220208337A1 (en) * | 2020-12-29 | 2022-06-30 | Kpn Innovations, Llc. | Systems and methods for generating a cancer alleviation nourishment plan |
| IT202100029210A1 (it) | 2021-11-18 | 2023-05-18 | Univ Degli Studi Di Teramo | MARCATORE PER LA DETERMINAZIONE DEL RISCHIO INFETTIVO DA SARS-CoV-2 |
| CN114561465B (zh) * | 2021-12-20 | 2024-01-26 | 上海锐翌生物科技有限公司 | 一种用于检测结直肠腺瘤的标志组合物及其早期诊断试剂 |
| WO2024056008A1 (zh) * | 2022-09-16 | 2024-03-21 | 江苏鹍远生物科技股份有限公司 | 鉴别癌症的甲基化标志物及应用 |
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| US4883750A (en) | 1984-12-13 | 1989-11-28 | Applied Biosystems, Inc. | Detection of specific sequences in nucleic acids |
| AU622426B2 (en) | 1987-12-11 | 1992-04-09 | Abbott Laboratories | Assay using template-dependent nucleic acid probe reorganization |
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| US6033854A (en) | 1991-12-16 | 2000-03-07 | Biotronics Corporation | Quantitative PCR using blocking oligonucleotides |
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| US5786146A (en) | 1996-06-03 | 1998-07-28 | The Johns Hopkins University School Of Medicine | Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids |
| CA2658290C (en) | 1996-06-04 | 2012-04-10 | University Of Utah Research Foundation | Monitoring hybridization during pcr using fluorescent dye specific to double-stranded dna |
| AU7164998A (en) | 1997-04-28 | 1998-11-24 | B-E Safe, Inc. | Taxonomic identification of microorganisms, proteins and peptides involved in vertebrate disease states |
| JP2002531066A (ja) * | 1998-11-05 | 2002-09-24 | パーカー ヒューズ インスティテュート | イカロス（ｉｋａｒｏｓ）アイソフォームおよび突然変異体 |
| US6331393B1 (en) | 1999-05-14 | 2001-12-18 | University Of Southern California | Process for high-throughput DNA methylation analysis |
| US6180349B1 (en) | 1999-05-18 | 2001-01-30 | The Regents Of The University Of California | Quantitative PCR method to enumerate DNA copy number |
| DE10019058A1 (de) | 2000-04-06 | 2001-12-20 | Epigenomics Ag | Detektion von Variationen des DNA-Methylierungsprofils |
| DE10130800B4 (de) | 2001-06-22 | 2005-06-23 | Epigenomics Ag | Verfahren zum Nachweis von Cytosin-Methylierung mit hoher Sensitivität |
| US7348142B2 (en) * | 2002-03-29 | 2008-03-25 | Veridex, Lcc | Cancer diagnostic panel |
| US20060199179A1 (en) * | 2002-06-19 | 2006-09-07 | Oncotherapy Science, Inc. | Method for diagnosis of colorectal tumors |
| ES2431944T3 (es) | 2002-06-26 | 2013-11-28 | Cold Spring Harbor Laboratory | Métodos para determinar los perfiles de metilación |
| JP3711984B2 (ja) | 2003-02-14 | 2005-11-02 | 日産自動車株式会社 | ハイブリッド車両の制御装置 |
| JP4453297B2 (ja) | 2003-05-27 | 2010-04-21 | トヨタ自動車株式会社 | 車両用遊星歯車式多段変速機 |
| CA2531451A1 (en) * | 2003-06-23 | 2005-01-06 | Epigenomics Ag | Methods and nucleic acids for analyses of colorectal cell proliferative disorders |
| AU2007237444B2 (en) * | 2006-04-17 | 2013-05-23 | Epigenomics Ag | Methods and nucleic acids for the detection of colorectal cell proliferative disorders |
| CA2676227A1 (en) * | 2007-02-12 | 2008-08-21 | The Johns Hopkins University | Early detection and prognosis of colon cancers |
| WO2008103761A2 (en) * | 2007-02-20 | 2008-08-28 | Sequenom, Inc. | Methods and compositions for cancer diagnosis and treatment based on nucleic acid methylation |
| EP2474629B1 (en) * | 2007-02-21 | 2015-04-22 | Oslo Universitetssykehus HF | New markers for cancer |
| US20100240057A1 (en) * | 2007-11-08 | 2010-09-23 | St. Jude Children's Research Hospital | Methods and compositions for the diagnosis and treatment of chronic myeloid leukemia and acute lymphoblastic leukemia |
| WO2009078931A2 (en) * | 2007-12-10 | 2009-06-25 | Brandeis University | Irf as a tumor suppressor and uses thereof |
| US10927415B2 (en) * | 2008-11-26 | 2021-02-23 | The Johns Hopkins University | Methods for identifying cancer risk |
| US8048634B2 (en) * | 2009-08-18 | 2011-11-01 | National Defense Medical Center | Cancer screening method |
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2011
- 2011-09-13 ES ES11824349T patent/ES2715226T3/es active Active
- 2011-09-13 CA CA2812115A patent/CA2812115C/en active Active
- 2011-09-13 US US13/822,592 patent/US20130338020A1/en not_active Abandoned
- 2011-09-13 DK DK11824349.2T patent/DK2616556T3/en active
- 2011-09-13 EP EP16153960.6A patent/EP3034629B1/en active Active
- 2011-09-13 BR BR112013005929-0A patent/BR112013005929B1/pt active IP Right Grant
- 2011-09-13 JP JP2013527424A patent/JP2013545437A/ja active Pending
- 2011-09-13 CN CN201180054458.XA patent/CN103314114B/zh active Active
- 2011-09-13 EP EP11824349.2A patent/EP2616556B1/en active Active
- 2011-09-13 WO PCT/AU2011/001176 patent/WO2012034170A1/en active Application Filing
- 2011-09-13 BR BR122020021163-6A patent/BR122020021163B1/pt active IP Right Grant
- 2011-09-13 NZ NZ608153A patent/NZ608153A/en not_active IP Right Cessation
- 2011-09-13 ES ES16153960T patent/ES2760919T3/es active Active
- 2011-09-13 EP EP16153959.8A patent/EP3034628B1/en active Active
- 2011-09-13 AU AU2011301770A patent/AU2011301770B2/en active Active
- 2011-09-13 CA CA3102758A patent/CA3102758C/en active Active
- 2011-09-13 DK DK18215882.4T patent/DK3508589T3/da active
- 2011-09-13 CN CN201610483760.1A patent/CN105886657B/zh active Active
- 2011-09-13 EP EP18215882.4A patent/EP3508589B1/en active Active
- 2011-09-13 DK DK16153960T patent/DK3034629T3/da active
- 2011-09-13 DK DK16153959.8T patent/DK3034628T5/en active
- 2011-09-13 ES ES16153959T patent/ES2707341T3/es active Active
- 2011-09-13 CA CA3154149A patent/CA3154149A1/en active Pending
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2016
- 2016-08-29 HK HK16110262.2A patent/HK1222208A1/zh unknown
- 2016-08-29 HK HK16110261.3A patent/HK1222207A1/zh unknown
- 2016-09-29 JP JP2016191583A patent/JP2017060474A/ja active Pending
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2018
- 2018-08-03 JP JP2018147091A patent/JP6673562B2/ja active Active
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2019
- 2019-10-02 JP JP2019182336A patent/JP6813242B2/ja active Active
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2020
- 2020-04-24 AU AU2020202747A patent/AU2020202747B2/en active Active
- 2020-12-14 JP JP2020206662A patent/JP7035156B2/ja active Active
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2022
- 2022-03-02 JP JP2022031776A patent/JP7547406B2/ja active Active
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2023
- 2023-05-04 US US18/312,471 patent/US20240052426A1/en active Pending
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