HK1216009A1 - 前列環素組合物及其使用方法 - Google Patents
前列環素組合物及其使用方法Info
- Publication number
- HK1216009A1 HK1216009A1 HK16103948.9A HK16103948A HK1216009A1 HK 1216009 A1 HK1216009 A1 HK 1216009A1 HK 16103948 A HK16103948 A HK 16103948A HK 1216009 A1 HK1216009 A1 HK 1216009A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- prostacylin
- compositions
- methods
- same
- prostacylin compositions
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/28—Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/5123—Organic compounds, e.g. fats, sugars
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Otolaryngology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Nanotechnology (AREA)
- Optics & Photonics (AREA)
- Dispersion Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261732223P | 2012-11-30 | 2012-11-30 | |
PCT/US2013/072647 WO2014085813A1 (en) | 2012-11-30 | 2013-12-02 | Prostacylin compositions and methods for using the same |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1216009A1 true HK1216009A1 (zh) | 2016-10-07 |
Family
ID=50828539
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK16103948.9A HK1216009A1 (zh) | 2012-11-30 | 2016-04-07 | 前列環素組合物及其使用方法 |
Country Status (12)
Country | Link |
---|---|
US (1) | US20150328232A1 (zh) |
EP (1) | EP2925303A4 (zh) |
JP (1) | JP6357481B2 (zh) |
KR (1) | KR20150089087A (zh) |
CN (1) | CN104822372A (zh) |
AU (1) | AU2013351934B2 (zh) |
BR (1) | BR112015012547A2 (zh) |
CA (1) | CA2890219A1 (zh) |
HK (1) | HK1216009A1 (zh) |
IL (1) | IL238984A0 (zh) |
NZ (1) | NZ707551A (zh) |
WO (1) | WO2014085813A1 (zh) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20190090092A (ko) | 2009-06-12 | 2019-07-31 | 맨카인드 코포레이션 | 한정된 비표면적을 갖는 디케토피페라진 마이크로입자 |
ES2754388T3 (es) | 2013-03-15 | 2020-04-17 | Mannkind Corp | Composiciones y métodos de dicetopiperazina microcristalina |
CN114848614A (zh) | 2013-07-18 | 2022-08-05 | 曼金德公司 | 热稳定性干粉药物组合物和方法 |
KR102427785B1 (ko) | 2013-10-25 | 2022-07-29 | 인스메드 인코포레이티드 | 프로스타사이클린 화합물, 조성물 및 이의 사용 방법 |
GB201400412D0 (en) * | 2014-01-10 | 2014-02-26 | Heart Biotech Ltd | Pharmaceutical formulations for the treatment of pulmonary arterial hypertension |
AU2015349969B2 (en) | 2014-11-18 | 2020-02-06 | Insmed Incorporated | Methods of manufacturing treprostinil and treprostinil derivative prodrugs |
US20180110774A1 (en) * | 2015-04-28 | 2018-04-26 | Stc. Unm | Compositions and methods for treatment of pulmonary hypertension |
WO2017019892A1 (en) * | 2015-07-28 | 2017-02-02 | Insmed Incorporated | Compositions comprising copper chelators and methods of use thereof for treating vasculopathies |
AU2017261317A1 (en) | 2016-05-05 | 2018-12-13 | Liquidia Technologies, Inc. | Dry powder treprostinil for the treatment of pulmonary hypertension |
CN107811970B (zh) * | 2016-09-12 | 2021-02-02 | 江苏艾立康药业股份有限公司 | 西里帕格多囊脂质体及其制备方法 |
SI3512495T1 (sl) * | 2016-09-15 | 2023-01-31 | Camurus Ab | Formulacije prostaciklinskih analogov |
CA3038276A1 (en) | 2016-09-26 | 2018-03-29 | United Therapeutics Corporation | Treprostinil prodrugs |
JP7186385B2 (ja) * | 2016-10-27 | 2022-12-09 | 国立大学法人大阪大学 | 疾患部位特異的リポソーム製剤 |
KR20230021186A (ko) * | 2016-11-10 | 2023-02-13 | 아레나 파마슈티칼스, 인크. | 라리네팍 및 다른 제제의 조합에 의한 pah의 치료 방법 |
EP3658134A4 (en) | 2017-07-24 | 2021-05-05 | Pharmosa Biopharm Inc. | LIPOSOME COMPOSITIONS CONTAINING LOW ACID MEDICINAL PRODUCTS AND USES THEREOF |
US20210113464A1 (en) * | 2017-11-27 | 2021-04-22 | Osaka University | Disease-site-specific liposomal formulation |
CA3099411A1 (en) * | 2018-05-07 | 2019-11-14 | Pharmosa Biopharm Inc. | Pharmaceutical composition for controlled release of treprostinil |
BR112021021775A2 (pt) * | 2019-04-29 | 2022-01-04 | Insmed Inc | Composições de pó seco de pró-fármacos de treprostinil e métodos de uso destas |
CA3139136A1 (en) * | 2019-05-14 | 2020-11-19 | Pharmosa Biopharm Inc. | Pharmaceutical composition of a weak acid drug and methods of administration |
US20210022994A1 (en) * | 2019-07-22 | 2021-01-28 | Lupin Holdings, B.V. | Sustained release trepostinil-compound microparticle compositions |
EP4017588A1 (en) | 2019-08-23 | 2022-06-29 | United Therapeutics Corporation | Treprostinil prodrugs |
IL296567A (en) | 2020-04-17 | 2022-11-01 | United Therapeutics Corp | Terfostinil for use in the treatment of interstitial lung disease |
JP2023529828A (ja) | 2020-06-09 | 2023-07-12 | ユナイテッド セラピューティクス コーポレイション | トレプロスチニルのフマリルジケトピペリジンプロドラッグ |
CN117062605A (zh) | 2020-12-14 | 2023-11-14 | 联合治疗公司 | 使用曲前列环素前药治疗疾病的方法 |
TW202320802A (zh) * | 2021-07-16 | 2023-06-01 | 美商塞萊托藥品股份有限公司 | Bcl抑制劑之脂質體調配物 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS61289034A (ja) * | 1985-06-17 | 1986-12-19 | Teijin Ltd | イソカルバサイクリン類脂肪乳剤 |
CA2091152C (en) * | 1993-03-05 | 2005-05-03 | Kirsten Westesen | Solid lipid particles, particles of bioactive agents and methods for the manfuacture and use thereof |
CN1173742C (zh) * | 1997-12-26 | 2004-11-03 | 山之内制药株式会社 | 缓释药物组合物 |
AU5068999A (en) * | 1998-07-31 | 2000-02-21 | Korea Institute Of Science And Technology | Lipid emulsion and solid lipid nanoparticle as a gene or drug carrier |
US6521212B1 (en) * | 1999-03-18 | 2003-02-18 | United Therapeutics Corporation | Method for treating peripheral vascular disease by administering benzindene prostaglandins by inhalation |
CN1791386A (zh) * | 2003-05-19 | 2006-06-21 | 巴克斯特国际公司 | 抗癫痫和抗痴呆药物以及免疫抑制剂的小-颗粒药物制剂 |
EP1479383B1 (en) * | 2003-05-20 | 2006-10-04 | Ethypharm | Oral sustained release pharmaceutical composition |
CA2959852A1 (en) * | 2003-05-22 | 2005-01-27 | United Therapeutics Corporation | Compounds and methods for delivery of prostacyclin analogs |
CN101090714A (zh) * | 2004-07-26 | 2007-12-19 | 康泽里克斯公司 | 通过吸入伊洛前列素和微粒制剂治疗肺动脉高血压症 |
US20070178166A1 (en) * | 2005-12-15 | 2007-08-02 | Acusphere, Inc. | Processes for making particle-based pharmaceutical formulations for pulmonary or nasal administration |
KR101390579B1 (ko) * | 2006-05-15 | 2014-05-19 | 유나이티드 세러퓨틱스 코오포레이션 | 정량 흡입기를 사용한 트레프로스티닐 투여 |
EP2144600A4 (en) * | 2007-04-04 | 2011-03-16 | Massachusetts Inst Technology | POLY (AMINIC ACID) TARGET MOLECULES |
RU2482851C2 (ru) * | 2009-02-20 | 2013-05-27 | Микро Лабс Лимитед | Хранение стабильного продукта простагландина |
CN101669904B (zh) * | 2009-09-29 | 2011-06-22 | 北京中海康医药科技发展有限公司 | 一种依前列醇脂质纳米粒及制备方法 |
WO2012107364A1 (en) * | 2011-02-07 | 2012-08-16 | Scipharm Sàrl | Novel composition for the treatment of cystic fibrosis |
JP5780775B2 (ja) * | 2011-02-18 | 2015-09-16 | 株式会社Lttバイオファーマ | プロスタグランジンi2誘導体を含有するナノ粒子 |
CN103561725B (zh) * | 2011-03-14 | 2018-08-31 | 国立大学法人北海道大学 | 用于肺递送的载体、导入剂及用途 |
-
2013
- 2013-12-02 AU AU2013351934A patent/AU2013351934B2/en not_active Ceased
- 2013-12-02 JP JP2015545499A patent/JP6357481B2/ja not_active Expired - Fee Related
- 2013-12-02 CN CN201380062668.2A patent/CN104822372A/zh active Pending
- 2013-12-02 US US14/648,632 patent/US20150328232A1/en not_active Abandoned
- 2013-12-02 NZ NZ70755113A patent/NZ707551A/en not_active IP Right Cessation
- 2013-12-02 WO PCT/US2013/072647 patent/WO2014085813A1/en active Application Filing
- 2013-12-02 EP EP13859435.3A patent/EP2925303A4/en not_active Withdrawn
- 2013-12-02 CA CA2890219A patent/CA2890219A1/en not_active Abandoned
- 2013-12-02 BR BR112015012547A patent/BR112015012547A2/pt not_active IP Right Cessation
- 2013-12-02 KR KR1020157017536A patent/KR20150089087A/ko unknown
-
2015
- 2015-05-25 IL IL238984A patent/IL238984A0/en unknown
-
2016
- 2016-04-07 HK HK16103948.9A patent/HK1216009A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
AU2013351934B2 (en) | 2018-03-29 |
JP2016501233A (ja) | 2016-01-18 |
EP2925303A4 (en) | 2016-04-27 |
NZ707551A (en) | 2019-10-25 |
EP2925303A1 (en) | 2015-10-07 |
US20150328232A1 (en) | 2015-11-19 |
KR20150089087A (ko) | 2015-08-04 |
AU2013351934A1 (en) | 2015-05-21 |
WO2014085813A1 (en) | 2014-06-05 |
CN104822372A (zh) | 2015-08-05 |
JP6357481B2 (ja) | 2018-07-11 |
IL238984A0 (en) | 2015-07-30 |
CA2890219A1 (en) | 2014-06-05 |
BR112015012547A2 (pt) | 2017-07-11 |
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