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HK1213777A1 - Inhibitors of cxcr1/2 as adjuvants in the transplant of pancreatic islets cxcr1/2 - Google Patents

Inhibitors of cxcr1/2 as adjuvants in the transplant of pancreatic islets cxcr1/2

Info

Publication number
HK1213777A1
HK1213777A1 HK16101720.7A HK16101720A HK1213777A1 HK 1213777 A1 HK1213777 A1 HK 1213777A1 HK 16101720 A HK16101720 A HK 16101720A HK 1213777 A1 HK1213777 A1 HK 1213777A1
Authority
HK
Hong Kong
Prior art keywords
cxcr1
transplant
adjuvants
inhibitors
pancreatic islets
Prior art date
Application number
HK16101720.7A
Other languages
Chinese (zh)
Inventor
洛倫佐．皮耶蒙蒂
路易莎．達豐希奧
馬爾塞洛．阿萊格雷蒂
Original Assignee
Dompe Farm Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dompe Farm Spa filed Critical Dompe Farm Spa
Publication of HK1213777A1 publication Critical patent/HK1213777A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
    • C07C311/51—Y being a hydrogen or a carbon atom

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Transplantation (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
HK16101720.7A 2009-10-06 2016-02-18 Inhibitors of cxcr1/2 as adjuvants in the transplant of pancreatic islets cxcr1/2 HK1213777A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP09172364A EP2308484A1 (en) 2009-10-06 2009-10-06 Inhibitors of cxcr1/2 as adjuvants in the transplant of pancreatic islets

Publications (1)

Publication Number Publication Date
HK1213777A1 true HK1213777A1 (en) 2016-07-15

Family

ID=41818891

Family Applications (2)

Application Number Title Priority Date Filing Date
HK13103030.1A HK1175993A1 (en) 2009-10-06 2013-03-12 Inhibitors of cxcr1/2 as adjuvants in the transplant of pancreatic islets cxcr1/2
HK16101720.7A HK1213777A1 (en) 2009-10-06 2016-02-18 Inhibitors of cxcr1/2 as adjuvants in the transplant of pancreatic islets cxcr1/2

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK13103030.1A HK1175993A1 (en) 2009-10-06 2013-03-12 Inhibitors of cxcr1/2 as adjuvants in the transplant of pancreatic islets cxcr1/2

Country Status (24)

Country Link
US (1) US20120202884A1 (en)
EP (2) EP2308484A1 (en)
JP (2) JP5834010B2 (en)
KR (2) KR101759362B1 (en)
CN (2) CN102665703B (en)
AU (1) AU2010305385B2 (en)
BR (1) BR112012007991B8 (en)
CA (1) CA2775902C (en)
CY (1) CY1115018T1 (en)
DK (1) DK2485723T3 (en)
EA (1) EA021298B1 (en)
ES (1) ES2451349T3 (en)
HK (2) HK1175993A1 (en)
HR (1) HRP20140202T1 (en)
IL (1) IL219037A (en)
ME (1) ME01719B (en)
MX (1) MX2012004082A (en)
NZ (1) NZ599172A (en)
PL (1) PL2485723T3 (en)
PT (1) PT2485723E (en)
RS (1) RS53249B (en)
SI (1) SI2485723T1 (en)
SM (1) SMT201400033B (en)
WO (1) WO2011042466A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2308485A1 (en) * 2009-10-06 2011-04-13 Dompé S.p.a. Sulfonamides for the prevention of diabetes
EP2308484A1 (en) * 2009-10-06 2011-04-13 Dompé S.p.a. Inhibitors of cxcr1/2 as adjuvants in the transplant of pancreatic islets
CN103159652B (en) * 2011-12-19 2016-06-08 天津市国际生物医药联合研究院 The preparation of sulfinyl amine compounds and application thereof
CN110420316A (en) 2013-06-18 2019-11-08 纽约大学 Participate in the cellular factor of the cytotoxicity of staphylococcus aureus leukocidin: novel therapeutic target spot
JP2019501766A (en) 2015-12-29 2019-01-24 ユーオーピー エルエルシー Binderless zeolite adsorbent and method for producing binderless zeolite adsorbent
CN109890364B (en) 2016-10-03 2023-10-17 儿童医疗中心公司 Prevention and treatment of diabetic nephropathy

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1303249B1 (en) 1998-10-23 2000-11-06 Dompe Spa SOME N- (2-ARYL-PROPIONYL) -SULPHONAMIDS AND PHARMACEUTICAL PREPARATIONS THAT CONTAIN THEM.
WO2001078653A2 (en) * 2000-04-14 2001-10-25 Millennium Pharmaceuticals, Inc. Graft rejection inhibition with ccr2 inhibitors
US20020018776A1 (en) * 2000-04-14 2002-02-14 Millennium Pharmaceuticals, Inc. Method of treating graft rejection using inhibitors of CXCR3 function
ITMI20010206A1 (en) * 2001-02-02 2002-08-02 Dompe Spa USE OF (R) -IBUPROFENE METHANE SULPHONAMIDE AND ITS NON-TOXIC SALTS FOR THE PREPARATION OF MEDICATIONS FOR TREATMENT AND PREVENTION
ME01763B (en) * 2004-03-23 2010-10-31 Dompe Farm Spa 2-phenylpropionic acid derivatives and pharmaceutical compositions containing them
ES2279248T3 (en) 2004-03-25 2007-08-16 Dompe' Pha.R.Ma S.P.A. USE OF N- (2-ARIL-PROPIONIL) -SULFONAMIDS FOR THE TREATMENT OF INJURIES OF THE SPINAL MEDULA.
US20050261762A1 (en) * 2004-05-21 2005-11-24 Medtronic Vascular, Inc. Medical devices to prevent or inhibit restenosis
JP4894518B2 (en) * 2004-09-13 2012-03-14 小野薬品工業株式会社 Nitrogen-containing heterocyclic derivatives and drugs containing them as active ingredients
WO2008000407A1 (en) * 2006-06-28 2008-01-03 Sanofi-Aventis Inhibitors of cxcr2
CA2664359A1 (en) * 2006-09-26 2008-04-03 Case Western Reserve University Cytokine signaling
US20110044988A1 (en) 2008-03-20 2011-02-24 Carolus Therpeutics, Inc. Methods of treatment using anti-mif antibodies
EP2308484A1 (en) * 2009-10-06 2011-04-13 Dompé S.p.a. Inhibitors of cxcr1/2 as adjuvants in the transplant of pancreatic islets

Also Published As

Publication number Publication date
CN102665703A (en) 2012-09-12
EA201270513A1 (en) 2012-11-30
EP2485723B1 (en) 2013-12-11
CA2775902C (en) 2016-11-29
CN104906572A (en) 2015-09-16
KR101817912B1 (en) 2018-02-21
WO2011042466A1 (en) 2011-04-14
DK2485723T3 (en) 2014-03-17
IL219037A0 (en) 2012-06-28
US20120202884A1 (en) 2012-08-09
EP2485723A1 (en) 2012-08-15
KR101759362B1 (en) 2017-07-18
RS53249B (en) 2014-08-29
JP2015145404A (en) 2015-08-13
JP6097328B2 (en) 2017-03-15
EP2308484A1 (en) 2011-04-13
BR112012007991B1 (en) 2020-12-15
EA021298B1 (en) 2015-05-29
BR112012007991B8 (en) 2021-05-25
ME01719B (en) 2014-09-20
HK1175993A1 (en) 2013-07-19
CN102665703B (en) 2016-04-20
PL2485723T3 (en) 2014-07-31
MX2012004082A (en) 2012-07-25
AU2010305385A1 (en) 2012-04-26
SMT201400033B (en) 2014-07-07
NZ599172A (en) 2014-03-28
JP2013506704A (en) 2013-02-28
SI2485723T1 (en) 2014-06-30
HRP20140202T1 (en) 2014-05-23
KR20120083440A (en) 2012-07-25
JP5834010B2 (en) 2015-12-16
PT2485723E (en) 2014-03-13
AU2010305385B2 (en) 2016-04-21
BR112012007991A2 (en) 2017-07-25
CY1115018T1 (en) 2017-01-25
ES2451349T3 (en) 2014-03-26
KR20170068625A (en) 2017-06-19
CA2775902A1 (en) 2011-04-14
IL219037A (en) 2015-01-29

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