HK1246372A1 - 檢測遺傳變異的系統和方法 - Google Patents
檢測遺傳變異的系統和方法Info
- Publication number
- HK1246372A1 HK1246372A1 HK18105718.0A HK18105718A HK1246372A1 HK 1246372 A1 HK1246372 A1 HK 1246372A1 HK 18105718 A HK18105718 A HK 18105718A HK 1246372 A1 HK1246372 A1 HK 1246372A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- methods
- genetic variation
- detecting genetic
- detecting
- variation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13/551,587 US20140024541A1 (en) | 2012-07-17 | 2012-07-17 | Methods and compositions for high-throughput sequencing |
| US13/551,584 US20140024536A1 (en) | 2012-07-17 | 2012-07-17 | Apparatus and methods for high-throughput sequencing |
| US13/551,590 US20140024542A1 (en) | 2012-07-17 | 2012-07-17 | Methods and compositions for enrichment of target polynucleotides |
| US13/665,671 US9092401B2 (en) | 2012-10-31 | 2012-10-31 | System and methods for detecting genetic variation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1246372A1 true HK1246372A1 (zh) | 2018-09-07 |
Family
ID=49949370
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK18105718.0A HK1246372A1 (zh) | 2012-07-17 | 2018-05-03 | 檢測遺傳變異的系統和方法 |
Country Status (9)
| Country | Link |
|---|---|
| EP (2) | EP3243937A1 (zh) |
| JP (3) | JP6285929B2 (zh) |
| CN (2) | CN104812947B (zh) |
| AU (2) | AU2013292610B2 (zh) |
| CA (1) | CA2876505A1 (zh) |
| ES (1) | ES2637538T3 (zh) |
| HK (1) | HK1246372A1 (zh) |
| IL (1) | IL236269A0 (zh) |
| WO (1) | WO2014015084A2 (zh) |
Families Citing this family (85)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8835358B2 (en) | 2009-12-15 | 2014-09-16 | Cellular Research, Inc. | Digital counting of individual molecules by stochastic attachment of diverse labels |
| JP6375230B2 (ja) | 2012-02-27 | 2018-08-15 | セルラー リサーチ， インコーポレイテッド | 分子計数のための組成物およびキット |
| KR102536833B1 (ko) | 2013-08-28 | 2023-05-26 | 벡톤 디킨슨 앤드 컴퍼니 | 대량의 동시 단일 세포 분석 |
| JP2017504307A (ja) | 2013-10-07 | 2017-02-09 | セルラー リサーチ， インコーポレイテッド | アレイ上のフィーチャーをデジタルカウントするための方法およびシステム |
| US11859246B2 (en) | 2013-12-11 | 2024-01-02 | Accuragen Holdings Limited | Methods and compositions for enrichment of amplification products |
| US11286519B2 (en) | 2013-12-11 | 2022-03-29 | Accuragen Holdings Limited | Methods and compositions for enrichment of amplification products |
| US10767222B2 (en) | 2013-12-11 | 2020-09-08 | Accuragen Holdings Limited | Compositions and methods for detecting rare sequence variants |
| US10006910B2 (en) | 2014-12-18 | 2018-06-26 | Agilome, Inc. | Chemically-sensitive field effect transistors, systems, and methods for manufacturing and using the same |
| US10020300B2 (en) | 2014-12-18 | 2018-07-10 | Agilome, Inc. | Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids |
| EP3235010A4 (en) | 2014-12-18 | 2018-08-29 | Agilome, Inc. | Chemically-sensitive field effect transistor |
| US9859394B2 (en) | 2014-12-18 | 2018-01-02 | Agilome, Inc. | Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids |
| US9618474B2 (en) | 2014-12-18 | 2017-04-11 | Edico Genome, Inc. | Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids |
| US9857328B2 (en) | 2014-12-18 | 2018-01-02 | Agilome, Inc. | Chemically-sensitive field effect transistors, systems and methods for manufacturing and using the same |
| US10697010B2 (en) | 2015-02-19 | 2020-06-30 | Becton, Dickinson And Company | High-throughput single-cell analysis combining proteomic and genomic information |
| CN107208158B (zh) | 2015-02-27 | 2022-01-28 | 贝克顿迪金森公司 | 空间上可寻址的分子条形编码 |
| EP3262189B1 (en) * | 2015-02-27 | 2021-12-08 | Becton, Dickinson and Company | Methods for barcoding nucleic acids for sequencing |
| WO2016160844A2 (en) | 2015-03-30 | 2016-10-06 | Cellular Research, Inc. | Methods and compositions for combinatorial barcoding |
| EP3286326B1 (en) | 2015-04-23 | 2025-01-22 | Becton, Dickinson and Company | Method for whole transcriptome amplification |
| WO2016172643A2 (en) | 2015-04-24 | 2016-10-27 | University Of Utah Research Foundation | Methods and systems for multiple taxonomic classification |
| WO2016196229A1 (en) | 2015-06-01 | 2016-12-08 | Cellular Research, Inc. | Methods for rna quantification |
| EP3347465B1 (en) | 2015-09-11 | 2019-06-26 | Cellular Research, Inc. | Methods and compositions for nucleic acid library normalization |
| SG11201802864RA (en) | 2015-10-09 | 2018-05-30 | Accuragen Holdings Ltd | Methods and compositions for enrichment of amplification products |
| CN105177160B (zh) * | 2015-10-16 | 2018-10-16 | 浙江大学 | 检测多种新生儿遗传代谢病致病基因的引物及试剂盒 |
| US12163184B2 (en) | 2015-12-03 | 2024-12-10 | Accuragen Holdings Limited | Methods and compositions for forming ligation products |
| WO2017165463A1 (en) | 2016-03-22 | 2017-09-28 | Counsyl, Inc. | Combinatorial dna screening |
| EP3437001A1 (en) * | 2016-03-29 | 2019-02-06 | Regeneron Pharmaceuticals, Inc. | Genetic variant-phenotype analysis system and methods of use |
| ES2956757T3 (es) | 2016-05-02 | 2023-12-27 | Becton Dickinson Co | Codificación con códigos de barras moleculares precisa |
| EP3459115A4 (en) | 2016-05-16 | 2020-04-08 | Agilome, Inc. | GRAPHENE FETING DEVICES, SYSTEMS, AND METHODS OF USE THEREOF FOR NUCLEIC ACID SEQUENCING |
| WO2017201102A1 (en) | 2016-05-16 | 2017-11-23 | Accuragen Holdings Limited | Method of improved sequencing by strand identification |
| US10301677B2 (en) | 2016-05-25 | 2019-05-28 | Cellular Research, Inc. | Normalization of nucleic acid libraries |
| EP3465502B1 (en) | 2016-05-26 | 2024-04-10 | Becton, Dickinson and Company | Molecular label counting adjustment methods |
| US10640763B2 (en) | 2016-05-31 | 2020-05-05 | Cellular Research, Inc. | Molecular indexing of internal sequences |
| US10202641B2 (en) | 2016-05-31 | 2019-02-12 | Cellular Research, Inc. | Error correction in amplification of samples |
| CN109997192A (zh) * | 2016-06-15 | 2019-07-09 | 哈佛学院董事及会员团体 | 用于基于规则的基因组设计的方法 |
| JP6966052B2 (ja) | 2016-08-15 | 2021-11-10 | アキュラーゲン ホールディングス リミテッド | 稀な配列変異体を検出するための組成物および方法 |
| KR102522023B1 (ko) | 2016-09-26 | 2023-04-17 | 셀룰러 리서치, 인크. | 바코딩된 올리고뉴클레오티드 서열을 갖는 시약을 이용한 단백질 발현의 측정 |
| WO2018081113A1 (en) * | 2016-10-24 | 2018-05-03 | Sawaya Sterling | Concealing information present within nucleic acids |
| WO2018089377A1 (en) | 2016-11-08 | 2018-05-17 | Cellular Research, Inc. | Methods for cell label classification |
| WO2018089378A1 (en) | 2016-11-08 | 2018-05-17 | Cellular Research, Inc. | Methods for expression profile classification |
| CN106611106B (zh) * | 2016-12-06 | 2019-05-03 | 北京荣之联科技股份有限公司 | 基因变异检测方法及装置 |
| JP7104048B2 (ja) | 2017-01-13 | 2022-07-20 | セルラー リサーチ， インコーポレイテッド | 流体チャネルの親水性コーティング |
| CN110382708A (zh) | 2017-02-01 | 2019-10-25 | 赛卢拉研究公司 | 使用阻断性寡核苷酸进行选择性扩增 |
| KR20220124280A (ko) | 2017-06-05 | 2022-09-13 | 백톤 디킨슨 앤드 컴퍼니 | 단일 세포를 위한 샘플 인덱싱 |
| CN108004301B (zh) * | 2017-12-15 | 2022-02-22 | 格诺思博生物科技南通有限公司 | 基因目标区域富集方法及建库试剂盒 |
| WO2019126209A1 (en) | 2017-12-19 | 2019-06-27 | Cellular Research, Inc. | Particles associated with oligonucleotides |
| CN108251502B (zh) * | 2017-12-27 | 2021-12-24 | 深圳华大基因股份有限公司 | 一种外周血游离肿瘤dna的富集方法、试剂盒及其应用 |
| CN108197433A (zh) * | 2017-12-29 | 2018-06-22 | 厦门极元科技有限公司 | 快速dna测序数据分析平台的数据内存和硬盘分流存储方法 |
| US11203782B2 (en) | 2018-03-29 | 2021-12-21 | Accuragen Holdings Limited | Compositions and methods comprising asymmetric barcoding |
| CN113383083B (zh) | 2018-04-27 | 2024-12-10 | 赛纳生物科技(北京)有限公司 | 用于制备多核苷酸的方法和组合物 |
| AU2019262048A1 (en) | 2018-05-03 | 2020-11-12 | Becton, Dickinson And Company | High throughput multiomics sample analysis |
| CN112243461B (zh) | 2018-05-03 | 2024-07-12 | 贝克顿迪金森公司 | 在相对的转录物末端进行分子条形码化 |
| WO2019241290A1 (en) | 2018-06-12 | 2019-12-19 | Accuragen Holdings Limited | Methods and compositions for forming ligation products |
| EP3815091A4 (en) * | 2018-06-29 | 2022-03-23 | Rady Children's Hospital Research Center | Method and system for sample identity assurance |
| GB201810901D0 (en) * | 2018-07-03 | 2018-08-15 | Ucb Biopharma Sprl | Method |
| CN109182483A (zh) * | 2018-09-04 | 2019-01-11 | 天津诺禾致源生物信息科技有限公司 | 基因变异解读的方法及装置 |
| JP2022511398A (ja) | 2018-10-01 | 2022-01-31 | ベクトン・ディキンソン・アンド・カンパニー | ５’転写物配列の決定 |
| EP3867400A4 (en) * | 2018-10-17 | 2022-07-27 | Quest Diagnostics Investments LLC | GENOME SEQUENCE SELECTION SYSTEM |
| JP7618548B2 (ja) | 2018-11-08 | 2025-01-21 | ベクトン・ディキンソン・アンド・カンパニー | ランダムプライミングを使用した単一細胞の全トランスクリプトーム解析 |
| CN109686439B (zh) * | 2018-12-04 | 2020-08-28 | 东莞博奥木华基因科技有限公司 | 遗传病基因检测的数据分析方法、系统及存储介质 |
| CN113195717A (zh) | 2018-12-13 | 2021-07-30 | 贝克顿迪金森公司 | 单细胞全转录组分析中的选择性延伸 |
| US11371076B2 (en) | 2019-01-16 | 2022-06-28 | Becton, Dickinson And Company | Polymerase chain reaction normalization through primer titration |
| EP3914728B1 (en) | 2019-01-23 | 2023-04-05 | Becton, Dickinson and Company | Oligonucleotides associated with antibodies |
| EP3924506A1 (en) | 2019-02-14 | 2021-12-22 | Becton Dickinson and Company | Hybrid targeted and whole transcriptome amplification |
| US11965208B2 (en) | 2019-04-19 | 2024-04-23 | Becton, Dickinson And Company | Methods of associating phenotypical data and single cell sequencing data |
| CN110349624B (zh) * | 2019-05-30 | 2021-09-21 | 山东省农业科学院玉米研究所 | sam文件flag标签定位T-DNA插入位点的方法 |
| JP6953586B2 (ja) | 2019-06-19 | 2021-10-27 | シスメックス株式会社 | 患者検体の核酸配列の解析方法、解析結果の提示方法、提示装置、提示プログラム、及び患者検体の核酸配列の解析システム |
| US11939622B2 (en) | 2019-07-22 | 2024-03-26 | Becton, Dickinson And Company | Single cell chromatin immunoprecipitation sequencing assay |
| BE1027463B1 (fr) | 2019-07-26 | 2021-02-23 | Safran Aero Boosters Sa | Outil de marquage par micro percussion, machine outil comprenant un outil de marquage et méthode de marquage par micro percussion |
| US11773436B2 (en) | 2019-11-08 | 2023-10-03 | Becton, Dickinson And Company | Using random priming to obtain full-length V(D)J information for immune repertoire sequencing |
| EP4090763B1 (en) | 2020-01-13 | 2024-12-04 | Becton Dickinson and Company | Methods and compositions for quantitation of proteins and rna |
| EP4471155A3 (en) | 2020-01-29 | 2024-12-18 | Becton, Dickinson and Company | Barcoded wells for spatial mapping of single cells through sequencing |
| EP4111168A1 (en) | 2020-02-25 | 2023-01-04 | Becton Dickinson and Company | Bi-specific probes to enable the use of single-cell samples as single color compensation control |
| US11574738B2 (en) | 2020-04-30 | 2023-02-07 | Optum Services (Ireland) Limited | Cross-variant polygenic predictive data analysis |
| US11967430B2 (en) | 2020-04-30 | 2024-04-23 | Optum Services (Ireland) Limited | Cross-variant polygenic predictive data analysis |
| US11610645B2 (en) * | 2020-04-30 | 2023-03-21 | Optum Services (Ireland) Limited | Cross-variant polygenic predictive data analysis |
| US11482302B2 (en) | 2020-04-30 | 2022-10-25 | Optum Services (Ireland) Limited | Cross-variant polygenic predictive data analysis |
| US11978532B2 (en) | 2020-04-30 | 2024-05-07 | Optum Services (Ireland) Limited | Cross-variant polygenic predictive data analysis |
| EP4150118A1 (en) | 2020-05-14 | 2023-03-22 | Becton Dickinson and Company | Primers for immune repertoire profiling |
| EP4407030A3 (en) | 2020-06-02 | 2024-09-11 | Becton, Dickinson and Company | Oligonucleotides and beads for 5 prime gene expression assay |
| US11932901B2 (en) | 2020-07-13 | 2024-03-19 | Becton, Dickinson And Company | Target enrichment using nucleic acid probes for scRNAseq |
| WO2022071952A1 (en) * | 2020-10-01 | 2022-04-07 | Google Llc | Linked dual barcode insertion constructs |
| CN112397144B (zh) * | 2020-10-29 | 2021-06-15 | 无锡臻和生物科技股份有限公司 | 检测基因突变及表达量的方法及装置 |
| WO2022109343A1 (en) | 2020-11-20 | 2022-05-27 | Becton, Dickinson And Company | Profiling of highly expressed and lowly expressed proteins |
| AU2024212457A1 (en) | 2023-01-23 | 2024-12-12 | Illumina, Inc. | Inferring microorganism of origin for antimicrobial resistance markers in targeted metagenomics |
| WO2025014806A1 (en) * | 2023-07-07 | 2025-01-16 | Myriad Genetics, Inc. | Multiple-ancestry polygenic risk assessment for breast cancer |
Family Cites Families (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5171534A (en) | 1984-01-16 | 1992-12-15 | California Institute Of Technology | Automated DNA sequencing technique |
| US5234809A (en) | 1989-03-23 | 1993-08-10 | Akzo N.V. | Process for isolating nucleic acid |
| WO1994024143A1 (en) | 1993-04-12 | 1994-10-27 | Northwestern University | Method of forming oligonucleotides |
| US5705628A (en) | 1994-09-20 | 1998-01-06 | Whitehead Institute For Biomedical Research | DNA purification and isolation using magnetic particles |
| US5750341A (en) | 1995-04-17 | 1998-05-12 | Lynx Therapeutics, Inc. | DNA sequencing by parallel oligonucleotide extensions |
| US5780613A (en) | 1995-08-01 | 1998-07-14 | Northwestern University | Covalent lock for self-assembled oligonucleotide constructs |
| GB9620209D0 (en) | 1996-09-27 | 1996-11-13 | Cemu Bioteknik Ab | Method of sequencing DNA |
| ES2563643T3 (es) | 1997-04-01 | 2016-03-15 | Illumina Cambridge Limited | Método de secuenciación de ácido nucleico |
| US20020076735A1 (en) * | 1998-09-25 | 2002-06-20 | Williams Lewis T. | Diagnostic and therapeutic methods using molecules differentially expressed in cancer cells |
| AR021833A1 (es) | 1998-09-30 | 2002-08-07 | Applied Research Systems | Metodos de amplificacion y secuenciacion de acido nucleico |
| US7056661B2 (en) | 1999-05-19 | 2006-06-06 | Cornell Research Foundation, Inc. | Method for sequencing nucleic acid molecules |
| US6056661A (en) | 1999-06-14 | 2000-05-02 | General Motors Corporation | Multi-range transmission with input split planetary gear set and continuously variable transmission unit |
| WO2001023610A2 (en) | 1999-09-29 | 2001-04-05 | Solexa Ltd. | Polynucleotide sequencing |
| US7582420B2 (en) * | 2001-07-12 | 2009-09-01 | Illumina, Inc. | Multiplex nucleic acid reactions |
| EP1990428B1 (en) * | 2000-02-07 | 2010-12-22 | Illumina, Inc. | Nucleic acid detection methods using universal priming |
| US6917726B2 (en) | 2001-09-27 | 2005-07-12 | Cornell Research Foundation, Inc. | Zero-mode clad waveguides for performing spectroscopy with confined effective observation volumes |
| US7001724B1 (en) | 2000-11-28 | 2006-02-21 | Applera Corporation | Compositions, methods, and kits for isolating nucleic acids using surfactants and proteases |
| US6558907B2 (en) * | 2001-05-16 | 2003-05-06 | Corning Incorporated | Methods and compositions for arraying nucleic acids onto a solid support |
| US7057026B2 (en) | 2001-12-04 | 2006-06-06 | Solexa Limited | Labelled nucleotides |
| US20030175828A1 (en) * | 2002-03-15 | 2003-09-18 | Lazar James G. | Signal amplification by Hybrid Capture |
| US20070037182A1 (en) | 2002-05-28 | 2007-02-15 | Gaskin James Z | Multiplex assays for inferring ancestry |
| DK3363809T3 (da) | 2002-08-23 | 2020-05-04 | Illumina Cambridge Ltd | Modificerede nukleotider til polynukleotidsekvensering |
| US20090124514A1 (en) * | 2003-02-26 | 2009-05-14 | Perlegen Sciences, Inc. | Selection probe amplification |
| EP3673986A1 (en) | 2004-01-07 | 2020-07-01 | Illumina Cambridge Limited | Improvements in or relating to molecular arrays |
| US7170050B2 (en) | 2004-09-17 | 2007-01-30 | Pacific Biosciences Of California, Inc. | Apparatus and methods for optical analysis of molecules |
| WO2006054722A1 (ja) * | 2004-11-19 | 2006-05-26 | Otsuka Pharmaceutical Co., Ltd. | 遺伝子を用いた熱不安定性フェノタイプ症のリスク診断法 |
| NZ562928A (en) * | 2005-04-18 | 2011-01-28 | Mitomics Inc | Mitochondrial mutations and rearrangements as a diagnostic tool for the detection of sun exposure, prostate cancer and other cancers |
| GB0514910D0 (en) | 2005-07-20 | 2005-08-24 | Solexa Ltd | Method for sequencing a polynucleotide template |
| GB0514936D0 (en) | 2005-07-20 | 2005-08-24 | Solexa Ltd | Preparation of templates for nucleic acid sequencing |
| GB0514909D0 (en) * | 2005-07-20 | 2005-08-24 | Solexa Ltd | Methods of nucleic acid amplification and sequencing |
| GB0522310D0 (en) | 2005-11-01 | 2005-12-07 | Solexa Ltd | Methods of preparing libraries of template polynucleotides |
| EP1969153A2 (en) | 2005-11-28 | 2008-09-17 | Pacific Biosciences of California, Inc. | Uniform surfaces for hybrid material substrates and methods for making and using same |
| CN100540680C (zh) * | 2006-01-24 | 2009-09-16 | 中国药品生物制品检定所 | 乙型肝炎病毒“a”决定簇的突变检测基因芯片 |
| CA2647786A1 (en) * | 2006-03-14 | 2007-09-20 | Genizon Biosciences Inc. | Methods and means for nucleic acid sequencing |
| EP2018622B1 (en) | 2006-03-31 | 2018-04-25 | Illumina, Inc. | Systems for sequence by synthesis analysis |
| US8178360B2 (en) | 2006-05-18 | 2012-05-15 | Illumina Cambridge Limited | Dye compounds and the use of their labelled conjugates |
| WO2008002502A2 (en) | 2006-06-23 | 2008-01-03 | Illumina, Inc. | Devices and systems for creation of dna cluster arrays |
| AU2007277125B2 (en) * | 2006-07-26 | 2013-08-01 | Yale University | Diagnosis and treatment of age related macular degeneration |
| US7754429B2 (en) | 2006-10-06 | 2010-07-13 | Illumina Cambridge Limited | Method for pair-wise sequencing a plurity of target polynucleotides |
| EP2121983A2 (en) | 2007-02-02 | 2009-11-25 | Illumina Cambridge Limited | Methods for indexing samples and sequencing multiple nucleotide templates |
| TWI460602B (zh) | 2008-05-16 | 2014-11-11 | Counsyl Inc | 廣用的懷孕前篩檢裝置 |
| US20120165215A1 (en) | 2009-06-26 | 2012-06-28 | The Regents Of The University Of California | Methods and systems for phylogenetic analysis |
| US9023769B2 (en) * | 2009-11-30 | 2015-05-05 | Complete Genomics, Inc. | cDNA library for nucleic acid sequencing |
| WO2011156529A2 (en) | 2010-06-08 | 2011-12-15 | Nugen Technologies, Inc. | Methods and composition for multiplex sequencing |
| KR20130101031A (ko) * | 2010-08-27 | 2013-09-12 | 제넨테크, 인크. | 핵산 포획 및 서열분석을 위한 방법 |
| EP3572528A1 (en) * | 2010-09-24 | 2019-11-27 | The Board of Trustees of the Leland Stanford Junior University | Direct capture, amplification and sequencing of target dna using immobilized primers |
-
2013
- 2013-07-17 AU AU2013292610A patent/AU2013292610B2/en not_active Ceased
- 2013-07-17 CN CN201380045879.5A patent/CN104812947B/zh not_active Expired - Fee Related
- 2013-07-17 CN CN201810260746.4A patent/CN108456717A/zh active Pending
- 2013-07-17 EP EP17170936.3A patent/EP3243937A1/en not_active Withdrawn
- 2013-07-17 CA CA2876505A patent/CA2876505A1/en not_active Abandoned
- 2013-07-17 ES ES13820115.7T patent/ES2637538T3/es active Active
- 2013-07-17 EP EP13820115.7A patent/EP2875173B1/en not_active Not-in-force
- 2013-07-17 WO PCT/US2013/050965 patent/WO2014015084A2/en active Application Filing
- 2013-07-17 JP JP2015523238A patent/JP6285929B2/ja not_active Expired - Fee Related
-
2014
- 2014-12-15 IL IL236269A patent/IL236269A0/en unknown
-
2017
- 2017-08-18 JP JP2017157845A patent/JP6234629B1/ja not_active Expired - Fee Related
- 2017-10-24 JP JP2017204976A patent/JP2018038417A/ja active Pending
-
2018
- 2018-05-03 HK HK18105718.0A patent/HK1246372A1/zh unknown
- 2018-08-17 AU AU2018217306A patent/AU2018217306A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2875173A4 (en) | 2015-12-30 |
| AU2013292610B2 (en) | 2018-05-17 |
| JP6285929B2 (ja) | 2018-02-28 |
| CN104812947B (zh) | 2018-04-27 |
| ES2637538T3 (es) | 2017-10-13 |
| JP6234629B1 (ja) | 2017-11-22 |
| IL236269A0 (en) | 2015-02-26 |
| JP2018038417A (ja) | 2018-03-15 |
| CN104812947A (zh) | 2015-07-29 |
| CN108456717A (zh) | 2018-08-28 |
| JP2018019701A (ja) | 2018-02-08 |
| JP2015531588A (ja) | 2015-11-05 |
| AU2013292610A1 (en) | 2015-01-22 |
| CA2876505A1 (en) | 2014-01-23 |
| EP2875173B1 (en) | 2017-06-28 |
| EP3243937A1 (en) | 2017-11-15 |
| WO2014015084A2 (en) | 2014-01-23 |
| AU2018217306A1 (en) | 2018-09-20 |
| EP2875173A2 (en) | 2015-05-27 |
| WO2014015084A3 (en) | 2014-03-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HK1246372A1 (zh) | 檢測遺傳變異的系統和方法 | |
| IL237480B (en) | Methods for identifying genetic changes | |
| SG11201604923XA (en) | Methods and systems for detecting genetic variants | |
| GB201616219D0 (en) | Methods and systems for detecting biological components | |
| EP2867659A4 (en) | SYSTEM AND METHOD FOR FLUID DETECTION | |
| EP2932268A4 (en) | SYSTEMS AND METHOD FOR RECOGNIZING A BIOLOGICAL CONDITION | |
| EP2923324A4 (en) | SYSTEM AND METHOD FOR SIMPLIFIED PAYMENT | |
| SG11201406250SA (en) | Method and system for detecting copy number variation | |
| HK1209834A1 (zh) | 物品檢測系統的方法 | |
| EP2828615A4 (en) | LASER GRAMMING SYSTEM AND METHOD | |
| SG11201404605TA (en) | Centrifugation system and related method | |
| GB201219800D0 (en) | System and method | |
| HK1197224A1 (zh) | 電梯的乘坐檢測系統 | |
| HUE042608T2 (hu) | Érzékelõ rendszer | |
| SG11201500746YA (en) | System and method for geothentication | |
| HK1209514A1 (zh) | 小額資源共享系統及其相應的方法 | |
| ZA201407686B (en) | Maize event dp-004114-3 and methods for detection thereof | |
| GB2510479B (en) | Touch system and method | |
| HK1212375A1 (zh) | 用於酶檢測的系統和方法 | |
| ZA201407867B (en) | Ore analysis system | |
| EP2936260A4 (en) | SYSTEM AND METHOD FOR CROSS CONTAMINATION PREVENTION | |
| HK1210307A1 (zh) | 以處方者為中心的指定系統和方法 | |
| GB201218836D0 (en) | Sensing systems, associated methods and apparatus | |
| GB201214511D0 (en) | Method and system | |
| GB201117142D0 (en) | Detection system |