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HK1037368A1 - Process for the synthesis of (1h)-benzo[c]quinolizin-3-ones derivatives - Google Patents

Process for the synthesis of (1h)-benzo[c]quinolizin-3-ones derivatives

Info

Publication number
HK1037368A1
HK1037368A1 HK01108153A HK01108153A HK1037368A1 HK 1037368 A1 HK1037368 A1 HK 1037368A1 HK 01108153 A HK01108153 A HK 01108153A HK 01108153 A HK01108153 A HK 01108153A HK 1037368 A1 HK1037368 A1 HK 1037368A1
Authority
HK
Hong Kong
Prior art keywords
benzo
quinolizin
alkyl
compound
tetrahydro
Prior art date
Application number
HK01108153A
Other languages
English (en)
Chinese (zh)
Other versions
HK1037368B (en
Inventor
A‧瓜尔内雅
M‧塞里奥
E‧G‧奥基阿托
Original Assignee
Laboratoires Serono S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Serono S.A. filed Critical Laboratoires Serono S.A.
Publication of HK1037368A1 publication Critical patent/HK1037368A1/xx
Publication of HK1037368B publication Critical patent/HK1037368B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D455/00Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/03Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/04Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/14Drugs for dermatological disorders for baldness or alopecia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Carbon And Carbon Compounds (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK01108153.5A 1998-08-03 1999-07-23 Process for the synthesis of (1h)-benzo[c]quinolizin-3-ones derivatives HK1037368B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP98114524 1998-08-03
EP98114524.6 1998-08-03
PCT/EP1999/005277 WO2000008019A1 (en) 1998-08-03 1999-07-23 Process for the synthesis of (1h)-benzo[c]quinolizin-3-ones derivatives

Publications (2)

Publication Number Publication Date
HK1037368A1 true HK1037368A1 (en) 2002-02-08
HK1037368B HK1037368B (en) 2004-06-18

Family

ID=

Also Published As

Publication number Publication date
ES2203169T3 (es) 2004-04-01
CA2338498A1 (en) 2000-02-17
PL198963B1 (pl) 2008-08-29
UA67787C2 (uk) 2004-07-15
NO20010559D0 (no) 2001-02-01
ATE250057T1 (de) 2003-10-15
PL345802A1 (en) 2002-01-02
US6723850B1 (en) 2004-04-20
CN1311788A (zh) 2001-09-05
NZ509243A (en) 2002-11-26
HUP0103241A3 (en) 2002-10-28
HUP0103241A2 (hu) 2002-01-28
SK1672001A3 (en) 2001-08-06
WO2000008019A1 (en) 2000-02-17
BR9912870A (pt) 2001-10-16
IL141212A0 (en) 2002-03-10
NO20010559L (no) 2001-02-01
DE69911430T2 (de) 2004-07-22
KR100624239B1 (ko) 2006-09-13
EA003997B1 (ru) 2003-12-25
CZ2001434A3 (cs) 2001-08-15
CA2338498C (en) 2009-05-19
ZA200100365B (en) 2001-07-26
EP1102765B1 (en) 2003-09-17
CZ291648B6 (cs) 2003-04-16
KR20010074684A (ko) 2001-08-09
DE69911430D1 (de) 2003-10-23
EA200100213A1 (ru) 2001-08-27
AU6312399A (en) 2000-02-28
BG65062B1 (bg) 2007-01-31
DK1102765T3 (da) 2004-02-02
AU751873B2 (en) 2002-08-29
TR200100286T2 (tr) 2001-07-23
EE200100060A (et) 2002-06-17
PT1102765E (pt) 2003-12-31
SK285438B6 (sk) 2007-01-04
BG105198A (en) 2001-12-29
SI1102765T1 (en) 2003-12-31
CN1128148C (zh) 2003-11-19
EP1102765A1 (en) 2001-05-30
EE04642B1 (et) 2006-06-15
IL141212A (en) 2006-12-31
JP2002522435A (ja) 2002-07-23

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20100723