HK1099286A1 - 5,7-diaminopyrazolo [4,3-d] pyrimidines with pde-5 inhibiting activity - Google Patents

5,7-diaminopyrazolo [4,3-d] pyrimidines with pde-5 inhibiting activity

Info

Publication number: HK1099286A1
Authority: HK; Hong Kong
Prior art keywords: diaminopyrazolo; pde; pyrimidines; inhibiting activity; inhibiting
Prior art date: 2003-11-24

Application number

HK07105414.0A

Other languages

English (en)

Inventor

Andrew Simon Bell

David Graham Brown

Kevin Neil Dack

David Nathan Abraham Fox

Ian Roger Marsh

Andrew Ian Morrell

Michael John Palmer

Carol Ann Winslow

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-11-24

Filing date

2007-05-22

Publication date

2007-08-10

2007-05-22 Application filed by Pfizer filed Critical Pfizer

2007-08-10 Publication of HK1099286A1 publication Critical patent/HK1099286A1/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pulmonology (AREA)
Diabetes (AREA)
Neurosurgery (AREA)
Reproductive Health (AREA)
Endocrinology (AREA)
Urology & Nephrology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Obesity (AREA)
Dermatology (AREA)
Hematology (AREA)
Vascular Medicine (AREA)
Hospice & Palliative Care (AREA)
Emergency Medicine (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Child & Adolescent Psychology (AREA)
Gynecology & Obstetrics (AREA)
Pregnancy & Childbirth (AREA)
Immunology (AREA)
Otolaryngology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

HK07105414.0A 2003-11-24 2007-05-22 5,7-diaminopyrazolo [4,3-d] pyrimidines with pde-5 inhibiting activity HK1099286A1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB0327319.0A GB0327319D0 (en)	2003-11-24	2003-11-24	Novel pharmaceuticals
PCT/IB2004/003747 WO2005049616A1 (en)	2003-11-24	2004-11-12	5,7-DIAMINOPYRAZOLO [4,3-d] PYRIMIDINES WITH PDE-5 INHIBITING ACTIVITY

Publications (1)

Publication Number	Publication Date
HK1099286A1 true HK1099286A1 (en)	2007-08-10

Family

ID=29764364

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
HK07105414.0A HK1099286A1 (en)	2003-11-24	2007-05-22	5,7-diaminopyrazolo [4,3-d] pyrimidines with pde-5 inhibiting activity
HK09107080.7A HK1128917A1 (en)	2003-11-24	2009-08-03	5,7-diaminopyrazolo [4,3-d] pyrimidines with pde-5 inhibiting activity

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
HK09107080.7A HK1128917A1 (en)	2003-11-24	2009-08-03	5,7-diaminopyrazolo [4,3-d] pyrimidines with pde-5 inhibiting activity

Country Status (44)

Country	Link
EP (1)	EP1689751B1 (xx)
JP (1)	JP4056015B2 (xx)
KR (2)	KR100893999B1 (xx)
CN (4)	CN101362764B (xx)
AP (1)	AP2227A (xx)
AR (1)	AR046711A1 (xx)
AT (1)	ATE485297T1 (xx)
AU (1)	AU2004290643B2 (xx)
BR (1)	BRPI0416869A (xx)
CA (1)	CA2546987C (xx)
CR (1)	CR8416A (xx)
CY (1)	CY1110933T1 (xx)
DE (1)	DE602004029705D1 (xx)
DK (1)	DK1689751T3 (xx)
EA (1)	EA011772B1 (xx)
EC (1)	ECSP066580A (xx)
ES (1)	ES2351622T3 (xx)
GB (1)	GB0327319D0 (xx)
GE (1)	GEP20084528B (xx)
HK (2)	HK1099286A1 (xx)
HR (1)	HRP20100651T1 (xx)
IL (1)	IL175433A (xx)
IS (1)	IS8406A (xx)
MA (1)	MA28172A1 (xx)
ME (1)	ME01216B (xx)
MX (1)	MXPA06005914A (xx)
MY (1)	MY140872A (xx)
NL (1)	NL1027568C2 (xx)
NO (1)	NO336526B1 (xx)
NZ (1)	NZ548097A (xx)
OA (1)	OA13289A (xx)
PA (1)	PA8617701A1 (xx)
PE (1)	PE20051061A1 (xx)
PL (1)	PL1689751T3 (xx)
PT (1)	PT1689751E (xx)
RS (1)	RS51556B (xx)
SG (1)	SG133614A1 (xx)
SI (1)	SI1689751T1 (xx)
TN (1)	TNSN06154A1 (xx)
TW (1)	TWI265031B (xx)
UA (1)	UA81994C2 (xx)
UY (1)	UY28625A1 (xx)
WO (1)	WO2005049616A1 (xx)
ZA (1)	ZA200602899B (xx)

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RS20050810A (xx) *	2003-04-29	2007-08-03	Pfizer Inc.,	5,7-diaminopirazolo(4,3-d)pirimidini korisni za lečenje hipertenzije

2003
- 2003-11-24 GB GBGB0327319.0A patent/GB0327319D0/en not_active Ceased
2004
- 2004-11-12 RS RSP-2010/0534A patent/RS51556B/en unknown
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- 2004-11-12 ME MEP-2010-203A patent/ME01216B/me unknown
- 2004-11-12 CN CN200910151866A patent/CN101647802A/zh active Pending
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- 2004-11-12 DE DE602004029705T patent/DE602004029705D1/de active Active
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2006
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2007
- 2007-05-22 HK HK07105414.0A patent/HK1099286A1/xx not_active IP Right Cessation
2009
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Also Published As

Publication number	Publication date
MY140872A (en)	2010-01-29
EA011772B1 (ru)	2009-06-30
AU2004290643A1 (en)	2005-06-02
EP1689751B1 (en)	2010-10-20
UY28625A1 (es)	2005-06-30
WO2005049616A1 (en)	2005-06-02
ES2351622T3 (es)	2011-02-08
WO2005049616A8 (en)	2006-06-01
JP2007512314A (ja)	2007-05-17
BRPI0416869A (pt)	2007-03-27
OA13289A (en)	2007-01-31
KR100848216B1 (ko)	2008-07-24
ATE485297T1 (de)	2010-11-15
ME01216B (me)	2013-03-20
TWI265031B (en)	2006-11-01
HK1128917A1 (en)	2009-11-13
ZA200602899B (en)	2007-07-25
AP2227A (en)	2011-03-29
ECSP066580A (es)	2006-12-20
EA200600677A1 (ru)	2006-12-29
AU2004290643B2 (en)	2008-08-07
NO336526B1 (no)	2015-09-21
IS8406A (is)	2006-04-10
CN1882591B (zh)	2011-08-10
IL175433A (en)	2011-08-31
HRP20100651T1 (hr)	2011-01-31
TW200520758A (en)	2005-07-01
CN101362765A (zh)	2009-02-11
PA8617701A1 (es)	2005-08-04
KR100893999B1 (ko)	2009-04-20
MXPA06005914A (es)	2006-06-27
CN101647802A (zh)	2010-02-17
IL175433A0 (en)	2006-09-05
PE20051061A1 (es)	2005-12-12
CA2546987A1 (en)	2005-06-02
CN101362764B (zh)	2011-04-20
CN101362765B (zh)	2011-02-02
GB0327319D0 (en)	2003-12-24
NL1027568C2 (nl)	2005-11-30
AP2006003591A0 (en)	2006-04-30
NL1027568A1 (nl)	2005-05-26
SI1689751T1 (sl)	2011-01-31
DE602004029705D1 (de)	2010-12-02
PL1689751T3 (pl)	2011-03-31
KR20070026334A (ko)	2007-03-08
NO20062950L (no)	2006-08-23
NZ548097A (en)	2008-12-24
DK1689751T3 (da)	2011-01-17
GEP20084528B (en)	2008-11-10
CA2546987C (en)	2009-05-12
CN1882591A (zh)	2006-12-20
MA28172A1 (fr)	2006-09-01
PT1689751E (pt)	2010-11-29
CY1110933T1 (el)	2015-06-10
CN101362764A (zh)	2009-02-11
TNSN06154A1 (fr)	2007-11-15
EP1689751A1 (en)	2006-08-16
KR20080052666A (ko)	2008-06-11
CR8416A (es)	2006-11-15
UA81994C2 (xx)	2008-02-25
RS51556B (en)	2011-06-30
AR046711A1 (es)	2005-12-21
JP4056015B2 (ja)	2008-03-05
SG133614A1 (en)	2007-07-30

Publication	Publication Date	Title
HK1099286A1 (en)	2007-08-10	5,7-diaminopyrazolo [4,3-d] pyrimidines with pde-5 inhibiting activity
IL182099A0 (en)	2007-07-24	Piperidinylamino-thieno[2,3-d] pyrimidine compounds
EP1599482A4 (en)	2008-10-01	PYRAZOLO1,5-A PYRIMIDINE DERIVATIVES
PL376916A1 (pl)	2006-01-09	Pochodne pirymido [4,5-d] pirymidyny o działaniu przeciwrakowym
IL170680A0 (en)	2009-02-11	8 - SUBSTITUTED - 6,7,8,9 -TETRAHYDROPYRIMIDO [1,2-a] PYRIMIDIN - 4 - ONE DERIVATIVES
TWI365189B (en)	2012-06-01	Novel pyrrolo[3,2-d]pyrimidin-4-one derivatives
EG24843A (en)	2010-10-13	Herbicidal pyrimidines
HK1088893A1 (en)	2006-11-17	Substituted 8-perfluoroalkyl-6,7,8,9-tetrahydropyrimidoÄ1,2-aÜ pyrimidin-4-one derivatives
EP1653969A4 (en)	2006-12-20	PYRROLO 1,2-B PYRIDAZINE DERIVATIVES
HK1091488A1 (en)	2007-01-19	Pyrimidine derivatives
ZA200604960B (en)	2007-11-28	Substituted 8'-pyri(mi)dinyl-dihydrospiro-[cycloalkylamine]-pyrimido[1,2-A]pyrimidin-6-onederivatives
AP2002002543A0 (en)	2002-06-30	Pyrrolo Ä2,3-dÜ pyrimidine compounds
IL172848A0 (en)	2006-06-11	2-substituted pyrimidines
ZA200510276B (en)	2007-03-28	Triazolopyrimidines
PL372989A1 (en)	2005-08-08	Triazolopyrimidines
MXPA03004498A (es)	2003-09-05	Uso de pirazolo (4,3-d)pirimidinas.
IL172845A0 (en)	2006-06-11	2-substituted pyrimidines
TWI372760B (en)	2012-09-21	A pyrazolo[1,5-a]pyrimidine compound
MXPA03004907A (es)	2003-09-05	Uso de pirazolo (4,3-d) pirimidinas.
IL173347A0 (en)	2006-06-11	7-SUBSTITUTED 3-NITRO-PYRAZOLO[1,5-a] PYRIMIDINES
TJ431B (en)	2007-06-05	2-Brom-7-methil-5-oxo-5h-1,3,4-thyodyazol-(3,2-a)pyrimidin, has antibacterial activity
SI1567522T1 (sl)	2008-02-29	Pirimidinske spojine
SI1549647T1 (sl)	2006-10-31	Substituirani C-imidazo(1,2-a)piridin-3-il-metilamini
IL173964A0 (en)	2006-07-05	HEXA-AND OCTAHYDRO-PYRIDO[1,2-a]PYRAZINE DERIVATIVES WITH NK1 ANTAGONISTIC ACTIVITY

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2019-06-21	PC	Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)	Effective date: 20181112