GT200600108A - Control de plagas - Google Patents
Control de plagasInfo
- Publication number
- GT200600108A GT200600108A GT200600108A GT200600108A GT200600108A GT 200600108 A GT200600108 A GT 200600108A GT 200600108 A GT200600108 A GT 200600108A GT 200600108 A GT200600108 A GT 200600108A GT 200600108 A GT200600108 A GT 200600108A
- Authority
- GT
- Guatemala
- Prior art keywords
- union
- fragments
- control
- new
- antibodies
- Prior art date
Links
- 241000607479 Yersinia pestis Species 0.000 title 1
- 239000012634 fragment Substances 0.000 abstract 4
- 239000000427 antigen Substances 0.000 abstract 3
- 102000036639 antigens Human genes 0.000 abstract 3
- 108091007433 antigens Proteins 0.000 abstract 3
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 210000001035 gastrointestinal tract Anatomy 0.000 abstract 2
- 230000003466 anti-cipated effect Effects 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
- A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
- A61K47/6817—Toxins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
- A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
- A61K47/6817—Toxins
- A61K47/6819—Plant toxins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
- A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
- A61K47/6817—Toxins
- A61K47/6819—Plant toxins
- A61K47/6825—Ribosomal inhibitory proteins, i.e. RIP-I or RIP-II, e.g. Pap, gelonin or dianthin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6843—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Botany (AREA)
- Zoology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Catching Or Destruction (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
LA PRESENTE INVNEICÓN SE REFIERE A NUEVOS AGENTES PARA EL CONTROL DE ROEDORES QUE COMPRENDEN ANTICUERPOS, O SUS FRAGMENTOS DE UNIÓN AL ANTÍGENO, QUE SE UNEN A PROTEÍNAS EXPRESADAS EN ROEDORES Y EN PARTICULAR ANTICUERPOS O FRAGMENTOS DE UNIÓN AL ANTÍGENO QUE SE UNEN A PROTEÍNAS EXPRESADAS EN EL TRACTO GASTROINTESTINAL (GI) DE ROEDORES, COMO ASÍ TAMBIÉN A MÉTODOS PARA PREPARAR TALES AGENTES DE CONTROL DE ROEDORES NUEVOS. LA INVENCIÓN ADEMÁS SE EXTIENDE A NUEVOS ANTICUERPOS Y FRAGMENTOS DE UNIÓN AL ANTÍGENO PARA UTILIZAR EN EL CONTROL DE ROEDORES COMO ASÍ TAMBIÉN A MÉTODOS PARA CONTROLAR LOS ROEDORES A TRAVÉS DEL USO DE TALES ANTICUERPOS, FRAGMENTOS DE UNIÓN AL ANTÍGENO Y NUEVOS AGENTES PARA EL CONTROL DE ROEDORES.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0505054A GB0505054D0 (en) | 2005-03-11 | 2005-03-11 | Antibodies |
GB0600719A GB0600719D0 (en) | 2006-01-13 | 2006-01-13 | Pest control |
Publications (1)
Publication Number | Publication Date |
---|---|
GT200600108A true GT200600108A (es) | 2006-10-25 |
Family
ID=36216798
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GT200600108A GT200600108A (es) | 2005-03-11 | 2006-03-10 | Control de plagas |
Country Status (17)
Country | Link |
---|---|
US (1) | US8349328B2 (es) |
EP (1) | EP1863849B1 (es) |
JP (1) | JP5032458B2 (es) |
AR (1) | AR052502A1 (es) |
AT (1) | ATE507245T1 (es) |
AU (1) | AU2006221823B2 (es) |
BR (1) | BRPI0608838A2 (es) |
CA (1) | CA2599465A1 (es) |
DE (1) | DE602006021552D1 (es) |
DK (1) | DK1863849T3 (es) |
GT (1) | GT200600108A (es) |
MX (1) | MX2007010899A (es) |
MY (1) | MY149858A (es) |
PL (1) | PL1863849T3 (es) |
PT (1) | PT1863849E (es) |
TW (1) | TWI396695B (es) |
WO (1) | WO2006095128A2 (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0721937D0 (en) | 2007-11-08 | 2007-12-19 | Secr Defence | Rodenticide |
ITBO20090012A1 (it) * | 2009-01-15 | 2010-07-16 | Vincenza Dolo | Composizione biocida e suo uso. |
US9200251B1 (en) | 2011-03-31 | 2015-12-01 | David Gordon Bermudes | Bacterial methionine analogue and methionine synthesis inhibitor anticancer, antiinfective and coronary heart disease protective microcins and methods of treatment therewith |
ITBO20120094A1 (it) * | 2012-02-28 | 2013-08-29 | Vincenza Dolo | Composizione biocida |
GB201221069D0 (en) * | 2012-11-23 | 2013-01-09 | Univ Reading | Control method |
WO2014127342A1 (en) * | 2013-02-18 | 2014-08-21 | University Of Maryland, Baltimore | Peptide additives for enhancing acceptance and ingestion of edibles by rodents and uses thereof |
MX2018014382A (es) * | 2016-05-23 | 2019-08-12 | Gries Gerhard | Atrayentes para roedores. |
EP3415010A1 (en) * | 2017-06-13 | 2018-12-19 | Agrosavfe Nv | Insect-controlling polypeptides and methods |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2633834A1 (de) * | 1975-08-19 | 1977-03-03 | Lipha | Nagetierbekaempfungsmittel und dessen verwendung |
US4851332A (en) | 1985-04-01 | 1989-07-25 | Sloan-Kettering Institute For Cancer Research | Choriocarcinoma monoclonal antibodies and antibody panels |
BE1000534A5 (fr) * | 1987-05-15 | 1989-01-17 | Billen E Ets Sprl | Composition pour l'extermination d'animaux rongeurs. |
US5290914A (en) * | 1988-04-28 | 1994-03-01 | Mycogen Corporation | Hybrid diphtheria-B.t. pesticidal toxins |
EP0347227B1 (en) * | 1988-06-17 | 1993-11-24 | E.I. Du Pont De Nemours And Company | Pesticidal compositions |
US6326467B1 (en) * | 1989-02-23 | 2001-12-04 | Colorado State University Research Foundation | Hormone-recombinant toxin compounds and methods for using same |
US5237051A (en) * | 1990-12-06 | 1993-08-17 | Vanderbilt University | Purified enterotoxin receptor protein |
WO1993019172A1 (en) | 1992-03-24 | 1993-09-30 | Cambridge Antibody Technology Limited | Methods for producing members of specific binding pairs |
ATE452975T1 (de) | 1992-08-21 | 2010-01-15 | Univ Bruxelles | Immunoglobuline ohne leichte ketten |
WO1994009817A1 (en) | 1992-11-04 | 1994-05-11 | City Of Hope | Novel antibody construct |
US5849870A (en) | 1993-03-25 | 1998-12-15 | Novartis Finance Corporation | Pesticidal proteins and strains |
IL116436A (en) | 1995-12-18 | 2006-12-31 | Yissum Res Dev Co | Fc?Á-PE CHIMERIC PROTEIN FOR TARGETED TREATMENT OF ALLERGY RESPONSES AND |
TW585921B (en) * | 1997-07-10 | 2004-05-01 | Res Dev Foundation | Species specific monoclonal antibodies and phage displayed Fab and scFV fragments for fragments for targeted destruction of imported fire ants |
ATE535154T1 (de) | 1998-03-12 | 2011-12-15 | Vhsquared Ltd | Produkten die inaktivierte hefen oder schimmel enthalten, die auf ihrer aussenoberfläche aktive antikörper haben |
US6492498B1 (en) * | 1999-11-15 | 2002-12-10 | Regents Of The University Of Minnesota | Multimeric immunotoxins |
AU2001236806A1 (en) | 2000-02-10 | 2001-08-20 | Research Development Foundation | Targeted destruction of pests |
CA2380443C (en) | 2000-05-26 | 2013-03-12 | Ginette Dubuc | Single-domain antigen-binding antibody fragments derived from llama antibodies |
GB0015935D0 (en) * | 2000-06-30 | 2000-08-23 | Univ Sheffield | Vaccine |
EP1433793A4 (en) * | 2001-09-13 | 2006-01-25 | Inst Antibodies Co Ltd | METHOD FOR CREATING A CAMEL ANTIBODY LIBRARY |
US20050009188A1 (en) * | 2002-09-19 | 2005-01-13 | Kitto G. Barrie | Animal immunocontraceptives expressed in plants and uses thereof |
-
2006
- 2006-02-17 PT PT06709799T patent/PT1863849E/pt unknown
- 2006-02-17 AU AU2006221823A patent/AU2006221823B2/en not_active Ceased
- 2006-02-17 BR BRPI0608838-4A patent/BRPI0608838A2/pt not_active Application Discontinuation
- 2006-02-17 DE DE602006021552T patent/DE602006021552D1/de active Active
- 2006-02-17 DK DK06709799.8T patent/DK1863849T3/da active
- 2006-02-17 WO PCT/GB2006/000562 patent/WO2006095128A2/en active Application Filing
- 2006-02-17 EP EP06709799A patent/EP1863849B1/en not_active Not-in-force
- 2006-02-17 US US11/908,347 patent/US8349328B2/en not_active Expired - Fee Related
- 2006-02-17 CA CA002599465A patent/CA2599465A1/en not_active Abandoned
- 2006-02-17 MX MX2007010899A patent/MX2007010899A/es active IP Right Grant
- 2006-02-17 AT AT06709799T patent/ATE507245T1/de active
- 2006-02-17 JP JP2008500249A patent/JP5032458B2/ja not_active Expired - Fee Related
- 2006-02-17 PL PL06709799T patent/PL1863849T3/pl unknown
- 2006-03-02 AR ARP060100791A patent/AR052502A1/es not_active Application Discontinuation
- 2006-03-02 TW TW095106993A patent/TWI396695B/zh not_active IP Right Cessation
- 2006-03-10 GT GT200600108A patent/GT200600108A/es unknown
- 2006-03-10 MY MYPI20061064A patent/MY149858A/en unknown
Also Published As
Publication number | Publication date |
---|---|
DE602006021552D1 (de) | 2011-06-09 |
US20100158892A1 (en) | 2010-06-24 |
TW200643031A (en) | 2006-12-16 |
US8349328B2 (en) | 2013-01-08 |
BRPI0608838A2 (pt) | 2010-02-02 |
CA2599465A1 (en) | 2006-09-14 |
EP1863849B1 (en) | 2011-04-27 |
MX2007010899A (es) | 2007-12-06 |
WO2006095128A3 (en) | 2006-11-30 |
PL1863849T3 (pl) | 2011-09-30 |
PT1863849E (pt) | 2011-05-10 |
JP2008532986A (ja) | 2008-08-21 |
MY149858A (en) | 2013-10-31 |
JP5032458B2 (ja) | 2012-09-26 |
AR052502A1 (es) | 2007-03-21 |
ATE507245T1 (de) | 2011-05-15 |
AU2006221823A1 (en) | 2006-09-14 |
EP1863849A2 (en) | 2007-12-12 |
WO2006095128A2 (en) | 2006-09-14 |
AU2006221823B2 (en) | 2011-06-09 |
TWI396695B (zh) | 2013-05-21 |
DK1863849T3 (da) | 2011-08-08 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
GT200600108A (es) | Control de plagas | |
CU20120095A7 (es) | Antagonistas de pcsk9 | |
CY1118576T1 (el) | Πρωτεϊνες δεσμευομενες με αντιγονο ανθρωπινης il-23 | |
CL2012000229A1 (es) | Anticuerpo humano aislado o un fragmento del mismo de unión al antígeno, que se une específicamente a la angiopoyetina-2 humana (hang-2) pero que no se une sustancialmente a la hang-1; composición farmacéutica que lo comprende; y su uso para el tratamiento de un tumor, hipertensión, diabetes, edema, enfermedad renal u ocular. | |
CO6231038A2 (es) | Proteinas de union, incluyendo anticuerpos derivados de anticuerpo y fragmentos de anticuerpo que se unen especificamente a cd154 y sus usos | |
CR20130621A (es) | Anticuerpos anti-angptl3 y usos de los mismos | |
PE20200152A1 (es) | Receptores de union a antigeno mejorados | |
GT200900121A (es) | Moleculas de enlace de lingo y uso farmaceutico | |
MX2017012352A (es) | Construccion dirigida a complejos de peptido de alfa-fetoproteina/complejo principal de histocompatibilidad (afp/cph) y usos de los mismos. | |
AR074360A1 (es) | Anticuerpo monoclonal o fragmento de union a antigeno del mismo composicion farmaceutica que lo comprende y su uso para preparar dicha composicion | |
CY1114658T1 (el) | Πρωτεϊνες δεσμευσης αντιγονου του αυξητικου παραγοντα τυπου επιδερμικου αυξητικου παραγοντα προσδεσης στην ηπαρινη | |
WO2016210365A3 (en) | Constructs targeting ny-eso-1 peptide/mhc complexes and uses thereof | |
PA8718601A1 (es) | Anticuerpos anti-5t4 y sus usos | |
GT201000148A (es) | Anticuerpos antimesotelina y usos de los mismos | |
CR20120310A (es) | Anticuerpos neutralizadores contra el receptor de prolactina y su uso terapéutico | |
PE20110306A1 (es) | Anticuerpos humanos que se unen al gen 3 de activacion linfocitaria (lag-3) | |
PE20120549A1 (es) | Proteinas biespecificas de union a antigenos | |
EA201700111A1 (ru) | Полипептидные конструкции и их применение | |
ECSP13012436A (es) | ANTICUERPOS PEPTÍDICOS BETA AMILOIDE ANTI-N3pGlu Y USOS DE LOS MISMOS | |
UY33826A (es) | Proteínas de unión con dominios trivariables y sus usos | |
CR20130112A (es) | Polipéptidos que enlazan miostatina, composiciones y métodos | |
ECSP13012402A (es) | Inmunoglobulinas con dominio variable dual y su uso | |
ATE553778T1 (de) | Für humanes hepcidin spezifische antikörper | |
PE20140190A1 (es) | Moduladores de proteinas notum y metodos de uso | |
EA201390254A1 (ru) | Модифицированные полипептиды релаксина и их применение |