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GR3020604T3 - Macrolide compositions for treating gastro-intestinal motility disorders - Google Patents

Macrolide compositions for treating gastro-intestinal motility disorders

Info

Publication number
GR3020604T3
GR3020604T3 GR960401963T GR960401963T GR3020604T3 GR 3020604 T3 GR3020604 T3 GR 3020604T3 GR 960401963 T GR960401963 T GR 960401963T GR 960401963 T GR960401963 T GR 960401963T GR 3020604 T3 GR3020604 T3 GR 3020604T3
Authority
GR
Greece
Prior art keywords
intestinal motility
motility disorders
treating gastro
macrolide compositions
macrolide
Prior art date
Application number
GR960401963T
Other languages
English (en)
Inventor
Jaswant Singh Gidda
Herbert Andrew Kirst
David Wayne Robertson
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of GR3020604T3 publication Critical patent/GR3020604T3/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Nutrition Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
GR960401963T 1988-04-18 1996-07-23 Macrolide compositions for treating gastro-intestinal motility disorders GR3020604T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/182,645 US4920102A (en) 1988-04-18 1988-04-18 Method for treating gastrointestinal disorders

Publications (1)

Publication Number Publication Date
GR3020604T3 true GR3020604T3 (en) 1996-10-31

Family

ID=22669415

Family Applications (1)

Application Number Title Priority Date Filing Date
GR960401963T GR3020604T3 (en) 1988-04-18 1996-07-23 Macrolide compositions for treating gastro-intestinal motility disorders

Country Status (22)

Country Link
US (1) US4920102A (el)
EP (1) EP0349100B1 (el)
JP (1) JPH0825882B2 (el)
KR (1) KR970009580B1 (el)
CN (1) CN1023017C (el)
AR (1) AR244699A1 (el)
AT (1) ATE139782T1 (el)
AU (1) AU616746B2 (el)
CA (1) CA1328257C (el)
DE (1) DE68926728T2 (el)
DK (1) DK183589A (el)
ES (1) ES2088388T3 (el)
GR (1) GR3020604T3 (el)
HU (1) HU206365B (el)
IE (1) IE72969B1 (el)
IL (1) IL89996A (el)
MX (1) MX15701A (el)
NZ (1) NZ228768A (el)
PH (1) PH26391A (el)
PT (1) PT90293B (el)
RU (1) RU2086560C1 (el)
ZA (1) ZA892801B (el)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5106961A (en) * 1987-05-26 1992-04-21 Eli Lilly And Company Erythromycin ring-contracted derivatives
US5068221A (en) * 1989-05-09 1991-11-26 Mathias John R Treatment of motility disorders with a gnrh analog
US5434136A (en) * 1990-12-14 1995-07-18 Mathias; John R. Treatment of motility disorders with a GNRH analog
US5523418A (en) * 1991-04-09 1996-06-04 Abbott Laboratories Macrocyclic lactam prokinetic agents
WO1992018134A1 (en) * 1991-04-09 1992-10-29 Abbott Laboratories Macrocyclic lactam prokinetic agents
DE4200145A1 (de) * 1992-01-07 1993-07-08 Kali Chemie Pharma Gmbh 7,10-epoxy-oxacyclododecan-derivate, verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
ATE164848T1 (de) * 1992-01-21 1998-04-15 Abbott Lab 4''-deoxyerythromycinderivate
DE69302938T2 (de) * 1992-03-19 1996-10-17 Kitasato Inst Erythromycinderivate, Herstellung und Verwendung davon
FR2697524B1 (fr) * 1992-11-05 1994-12-23 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
US5712253A (en) * 1996-06-18 1998-01-27 Abbott Laboratories Macrocyclic 13-membered ring derivatives of erythromycins A and B
DE19644195A1 (de) * 1996-10-24 1998-04-30 Solvay Pharm Gmbh 10,13,15-Trioxatricyclo[9.2.1.1.·9·.·6·]-pentadecanon-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US6165985A (en) * 1998-02-13 2000-12-26 Solvay Pharmaceuticals Gmbh 11-acetyl-12,13-dioxabicyclo[8.2.1]-tridecenone derivatives, processes for their preparation and pharmaceutical compositions comprising them
DE19805822B4 (de) * 1998-02-13 2009-02-05 Solvay Pharmaceuticals Gmbh 11-Acetyl-12,13-dioxabicyclo[8.2.1]tridecenon-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US5955440A (en) * 1998-03-27 1999-09-21 Abbott Laboratories Macrolide LHRH antagonists
US5972898A (en) * 1998-03-27 1999-10-26 Abbott Laboratories 3',3-N-bis-substituted macrolide LHRH antagonists
US6020521A (en) * 1998-08-26 2000-02-01 Abbott Laboratories Macrolide LHRH antagonists
US6387885B1 (en) 1998-08-26 2002-05-14 Abbott Laboratories 3′,3′-N-bis-desmethyl-3′-N-cycloalkyl erythromycin derivatives as LHRH antagonists
US6451806B2 (en) 1999-09-29 2002-09-17 Adolor Corporation Methods and compositions involving opioids and antagonists thereof
US6469030B2 (en) 1999-11-29 2002-10-22 Adolor Corporation Methods for the treatment and prevention of ileus
ATE316977T1 (de) * 2000-08-17 2006-02-15 Kitasato Inst Neue pseudoerythromycin derivate
GB0123400D0 (en) 2001-09-28 2001-11-21 Novartis Ag Organic compounds
US20040067896A1 (en) * 2002-07-25 2004-04-08 The Kitasato Institute Novel pseudoerythromycin derivatives
WO2004039823A1 (ja) * 2002-10-29 2004-05-13 The Kitasato Institute 抗真菌活性増強作用を有する新規マクロライド誘導体
ATE457995T1 (de) * 2003-06-18 2010-03-15 Tranzyme Pharma Inc Makrozyklische motilin rezeptorantagonisten
JP2009518396A (ja) * 2005-12-08 2009-05-07 ファイザー・インク エリスロマイシン化合物の３’−ジメチルアミノ基を脱メチルする方法
CN101528765B (zh) 2006-09-11 2015-04-22 欧塞拉治疗有限公司 用于治疗胃肠动力障碍病症的促胃动素受体的大环拮抗剂
US20080287371A1 (en) * 2007-05-17 2008-11-20 Tranzyme Pharma Inc. Macrocyclic antagonists of the motilin receptor for modulation of the migrating motor complex
FR2995605B1 (fr) * 2012-09-18 2014-09-19 Sanofi Sa Derives de macrolides, leur preparation et leur application therapeutique.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4547491A (en) * 1984-07-18 1985-10-15 Merck & Co., Inc. C-8A-Oxo-avermectin and milbemycin derivatives, pharmaceutical compositions and method of use
JPS6187625A (ja) * 1984-10-05 1986-05-06 Satoshi Omura 消化管収縮運動促進剤
DE3689758T2 (de) * 1985-08-31 1994-08-18 Kitasato Inst Erythromycinderivat und Verfahren zu dessen Herstellung.
CA1321581C (en) * 1987-05-26 1993-08-24 Herbert A. Kirst Ring-contracted macrolides

Also Published As

Publication number Publication date
AU616746B2 (en) 1991-11-07
IL89996A (en) 1994-08-26
AR244699A1 (es) 1993-11-30
DK183589D0 (da) 1989-04-17
CA1328257C (en) 1994-04-05
US4920102A (en) 1990-04-24
MX15701A (es) 1993-11-01
EP0349100A2 (en) 1990-01-03
JPH0825882B2 (ja) 1996-03-13
ES2088388T3 (es) 1996-08-16
KR900016220A (ko) 1990-11-12
PT90293B (pt) 1994-07-29
RU2086560C1 (ru) 1997-08-10
DE68926728T2 (de) 1996-11-28
CN1023017C (zh) 1993-12-08
IE891224L (en) 1989-10-18
ZA892801B (en) 1990-12-28
NZ228768A (en) 1990-10-26
PH26391A (en) 1992-07-02
IL89996A0 (en) 1989-12-15
ATE139782T1 (de) 1996-07-15
KR970009580B1 (en) 1997-06-14
CN1037517A (zh) 1989-11-29
PT90293A (pt) 1989-11-10
JPH01311096A (ja) 1989-12-15
DE68926728D1 (de) 1996-08-01
HU206365B (en) 1992-10-28
IE72969B1 (en) 1997-05-07
HUT49625A (en) 1989-10-30
DK183589A (da) 1989-10-19
AU3310789A (en) 1989-10-19
EP0349100B1 (en) 1996-06-26
EP0349100A3 (en) 1991-11-13

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