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GB651113A - Process for the manufacture of aqueous solutions of riboflavin - Google Patents

Process for the manufacture of aqueous solutions of riboflavin

Info

Publication number
GB651113A
GB651113A GB30512/48A GB3051248A GB651113A GB 651113 A GB651113 A GB 651113A GB 30512/48 A GB30512/48 A GB 30512/48A GB 3051248 A GB3051248 A GB 3051248A GB 651113 A GB651113 A GB 651113A
Authority
GB
United Kingdom
Prior art keywords
riboflavin
vitamin
aqueous solutions
ethyl
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB30512/48A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Products Ltd
Original Assignee
Roche Products Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Products Ltd filed Critical Roche Products Ltd
Publication of GB651113A publication Critical patent/GB651113A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/525—Isoalloxazines, e.g. riboflavins, vitamin B2

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Stable aqueous solutions of riboflavin are obtained by incorporating therein a lower aliphatic (e.g. ethyl or propyl) hydroxy amide of gentisic acid. Additional vitamins, e.g. vitamin B1, niacinamide, pantothenic acid and vitamin C may be added. Gentisic acid amides may be obtained by reacting a gentisic acid ester, e.g. methyl or ethyl gentisate, with a lower aliphatic hydroxy amine, e.g. monoethanolamine or isopropanolamine.ALSO:Stable aqueous solutions of riboflavin are obtained by incorporating therein a lower aliphatic (e.g. ethyl or propyl) hydroxy amide of gentisix acid. Additional vitamins, e.g. vitamin B, niacinamide, pantothenic acid and vitamin C may be added.
GB30512/48A 1948-01-31 1948-11-24 Process for the manufacture of aqueous solutions of riboflavin Expired GB651113A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US651113XA 1948-01-31 1948-01-31

Publications (1)

Publication Number Publication Date
GB651113A true GB651113A (en) 1951-03-14

Family

ID=22060402

Family Applications (1)

Application Number Title Priority Date Filing Date
GB30512/48A Expired GB651113A (en) 1948-01-31 1948-11-24 Process for the manufacture of aqueous solutions of riboflavin

Country Status (1)

Country Link
GB (1) GB651113A (en)

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