GB534746A - Improvements in or relating to the preparation of salts or esters of 2-keto aldonic acids - Google Patents
Improvements in or relating to the preparation of salts or esters of 2-keto aldonic acidsInfo
- Publication number
- GB534746A GB534746A GB28060/39A GB2806039A GB534746A GB 534746 A GB534746 A GB 534746A GB 28060/39 A GB28060/39 A GB 28060/39A GB 2806039 A GB2806039 A GB 2806039A GB 534746 A GB534746 A GB 534746A
- Authority
- GB
- United Kingdom
- Prior art keywords
- acid
- sodium
- keto
- treated
- produce
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
- C07H7/02—Acyclic radicals
- C07H7/027—Keto-aldonic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
534,746. 2-keto-aldonic acids. PFIZER & CO., C. Oct. 17, 1939, Nos. 28060, 28061 and 28062. Convention dates, Dec. 24, 1938, Aug. 5, 1939 and Aug. 5, 1939. [Class 2 (iii] Salts and esters of 2-keto-aldonic acids are made by the oxidation of aldonic acids or their lactones, esters, or salts by soluble chlorates in the presence of vanadium catalysts in a mildly acid medium. In examples (1) sodium-d-gluconate and sodium chlorate' are dissolved in water and acetic acid and vanadium oxide are added, the mixture being allowed to stand for 40 hours ; vanadium oxide is filtered off and the remainder of the vanadium is removed as ferrocyanide ; methyl alcohol and hydrogen chloride are added to produce methyl-2-keto-gluconate ; (2) sodium 2-ketol-lidonate which is identical with sodium-2-ketol-gulonate is made similarly from sodium l-idonate, using phosphoric acid instead of acetic ; this salt may be converted into ascorbic acid by adding sulphuric acid, evaporating to dryness, adding methyl alcohol, filtering, and refluxing with hydrogen chloride to form the methyl ester which is suspended in methyl alcohol, heated with sodium methylate and finally treated with sulphuric acid ; (3) sodiuml-gulonate is treated to produce sodium-2-ketogulonate, sodium acetate being used with the acetic acid ; (4) sodium-d-galactonate is treated to produce sodium 2-keto-d-galactonate, using phosphoric acid and sodium di-hydrogen phosphate the product is converted to the brucine salt; (6) the 8-lactone of gluconic acid is treated to produce the methyl ester of 2-keto-gluconic acid, using phosphoric acid ; (8) l-galactonic acid is treated to produce the methyl ester of 2-keto-galactonic acid, using phosphoric acid ; (10) the r-lactone of dmannonic acid is dissolved in methyl alcohol containing sodium chlorate and phosphoric acid, heated under reflux and shaken with vanadium pentoxide for four days, yielding the methyl ester of 2-keto-gluconic acid.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US534746XA | 1938-12-24 | 1938-12-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB534746A true GB534746A (en) | 1941-03-17 |
Family
ID=21984506
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB28060/39A Expired GB534746A (en) | 1938-12-24 | 1939-10-17 | Improvements in or relating to the preparation of salts or esters of 2-keto aldonic acids |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB534746A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992007108A1 (en) * | 1990-10-11 | 1992-04-30 | Pfizer Inc. | Oxygen removal with keto-gluconates |
-
1939
- 1939-10-17 GB GB28060/39A patent/GB534746A/en not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992007108A1 (en) * | 1990-10-11 | 1992-04-30 | Pfizer Inc. | Oxygen removal with keto-gluconates |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES416948A1 (en) | Diphosphinic acid esters and process for making same | |
| GB1347074A (en) | Solid phosphoric acid catalyst and method of manufacture and use thereof | |
| ATE8995T1 (en) | HYDROXYLALKYL PURINE ESTER, PROCESS FOR THEIR PREPARATION AND THERAPEUTIC COMPOSITION CONTAINING THESE ESTERS AS ACTIVE INGREDIENTS. | |
| ES460098A1 (en) | Derivatives of penicillanic acid | |
| ES398036A1 (en) | T2-phosphonobutane 1,2,4-tricarboxylic acid compounds process for their preparation and their use as complex formers | |
| GB1042631A (en) | New fused polycyclic hydrocarbon derivatives and processes for the preparation thereof | |
| SU727139A3 (en) | Method of preparing optically active 11-desoxy-16-aryl-omega-tetranorprostaglandines or their racemates or their salts | |
| GB534746A (en) | Improvements in or relating to the preparation of salts or esters of 2-keto aldonic acids | |
| SU506298A3 (en) | The method of obtaining derivatives of izikhinolinteofillina | |
| GB1097531A (en) | Improvements in or relating to the preparation of cyclopentane derivatives | |
| Friess et al. | Nature of the Acetyl Cholinesterase Surface. II. The Ring Effect in Enzymatic Inhibitors of the Substituted Ethylenediamine Type1 | |
| GB1432503A (en) | Cycloalkylalkylesters and process for their preparation | |
| ES8104222A1 (en) | Alkylcarbapenems, their preparation, use in pharmaceutical compositions and intermediates. | |
| FR2457865A1 (en) | ALLYLIC AND PROPYLIC DERIVATIVES OF RESORCYLIC ACID LACTONES, THEIR USE AS GROWTH PROMOTERS AND THEIR PREPARATION METHODS | |
| JPS607961B2 (en) | fair skin cosmetics | |
| DE2324767C2 (en) | 7-Benzoylindolin-2-one and process for its preparation | |
| DE69323998T2 (en) | PHARMACEUTICAL ACTIVE FLAVILIUM COMPOUNDS | |
| DE2901452C2 (en) | Pharmaceutical preparations for the external treatment of psoriasis | |
| AT216499B (en) | Process for the preparation of β- (4-methoxybenzoyl) -β-haloacrylic acids | |
| GB565564A (en) | Improvements in or relating to the preparation of 2-keto-l-galactonic acid, its alkali metal salts and methyl ester | |
| SU413148A1 (en) | ||
| GB152946A (en) | Improvements in or relating to the production of table vinegar | |
| GB1268008A (en) | ESTERS OF p-BYPHENYLYLACETIC ACID | |
| DE322746C (en) | Process for the preparation of ethylidene diacetate | |
| SU539435A1 (en) | Di-(para-toluenesulfonate)bis/n-methyl-n-(1-adamantyl) aminoethyl/ succinate as nondepolarizing short active myorelaxing agent |