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GB2288807B - Production of delta-latroinsectotoxin - Google Patents

Production of delta-latroinsectotoxin

Info

Publication number
GB2288807B
GB2288807B GB9508298A GB9508298A GB2288807B GB 2288807 B GB2288807 B GB 2288807B GB 9508298 A GB9508298 A GB 9508298A GB 9508298 A GB9508298 A GB 9508298A GB 2288807 B GB2288807 B GB 2288807B
Authority
GB
United Kingdom
Prior art keywords
latroinsectotoxin
delta
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
GB9508298A
Other versions
GB2288807A (en
GB9508298D0 (en
Inventor
David Robert Bell
Peter Norman Russell Usherwood
Irina Dulubova
Tatiana Volkova
Eugene Grishin
Valery Krasnoperov
Tatyana Genrikhovna Galkina
Mikhail Vladimirivic Khvotchev
Kirill Andreeevich Pluzhnikov
Oleg Grigorievich Shamotienko
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BTG International Ltd
Original Assignee
British Technology Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by British Technology Group Ltd filed Critical British Technology Group Ltd
Publication of GB9508298D0 publication Critical patent/GB9508298D0/en
Publication of GB2288807A publication Critical patent/GB2288807A/en
Application granted granted Critical
Publication of GB2288807B publication Critical patent/GB2288807B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43513Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
    • C07K14/43518Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from spiders
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01HNEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H1/00Processes for modifying genotypes ; Plants characterised by associated natural traits
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/50Isolated enzymes; Isolated proteins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Insects & Arthropods (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Environmental Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Dentistry (AREA)
  • Pest Control & Pesticides (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Agronomy & Crop Science (AREA)
  • Botany (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
GB9508298A 1994-04-27 1995-04-24 Production of delta-latroinsectotoxin Expired - Fee Related GB2288807B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9408466A GB9408466D0 (en) 1994-04-27 1994-04-27 Cloning and functional expression of neurotoxins

Publications (3)

Publication Number Publication Date
GB9508298D0 GB9508298D0 (en) 1995-06-14
GB2288807A GB2288807A (en) 1995-11-01
GB2288807B true GB2288807B (en) 1998-12-23

Family

ID=10754294

Family Applications (2)

Application Number Title Priority Date Filing Date
GB9408466A Pending GB9408466D0 (en) 1994-04-27 1994-04-27 Cloning and functional expression of neurotoxins
GB9508298A Expired - Fee Related GB2288807B (en) 1994-04-27 1995-04-24 Production of delta-latroinsectotoxin

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB9408466A Pending GB9408466D0 (en) 1994-04-27 1994-04-27 Cloning and functional expression of neurotoxins

Country Status (11)

Country Link
EP (1) EP0804571A1 (en)
JP (1) JP2000511761A (en)
KR (1) KR970702916A (en)
CN (1) CN1147272A (en)
AU (1) AU701101B2 (en)
BR (1) BR9507507A (en)
CA (1) CA2187920A1 (en)
GB (2) GB9408466D0 (en)
HU (1) HUT76255A (en)
WO (1) WO1995029235A1 (en)
ZA (1) ZA953384B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA99011191A (en) * 1999-12-03 2005-04-04 Univ Mexico Nacional Autonoma Immunogen, antivenom and vaccine against the venom of the black widow spider.
CL2007003884A1 (en) 2007-12-31 2009-09-25 Laboratorios Andromaco S A Peptide derived from the venom of the black widow spider, procedure for preparing said peptide, pharmaceutical composition comprising it, and use of said composition for the preparation of a medically useful for the treatment of sexual dysfunction.
CN114107353B (en) * 2021-10-29 2024-07-23 成都佩德生物医药有限公司 Plasmid for efficiently expressing polypeptide toxin and preparation method and application thereof

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2100737A (en) * 1981-06-17 1983-01-06 Celltech Ltd A process for the production of a polypeptide
GB2216127A (en) * 1988-02-25 1989-10-04 Sandoz Ltd Endotoxin muteins
EP0358557A2 (en) * 1988-09-06 1990-03-14 Plant Genetic Systems, N.V. Plants transformed with a DNA sequence from bacillus thuringiensis lethal to lepidoptera
GB2242681A (en) * 1990-04-05 1991-10-09 Ciba Geigy Ag Hirudin fragments
WO1991016433A1 (en) * 1990-04-26 1991-10-31 Plant Genetic Systems N.V. New bacillus thuringiensis strains and their genes encoding insecticidal toxins
GB2246783A (en) * 1989-04-29 1992-02-12 Delta Biotechnology Ltd Fusion proteins containing n-terminal fragments of human serum albumin
GB2249099A (en) * 1990-09-26 1992-04-29 Squibb & Sons Inc Squalene synthetase
GB2249100A (en) * 1990-10-09 1992-04-29 Toyo Jozo Kk Expression of M-CSF deletion mutant polypeptides
WO1993015192A1 (en) * 1992-01-24 1993-08-05 Fmc Corporation Insecticidally effective peptides

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2100737A (en) * 1981-06-17 1983-01-06 Celltech Ltd A process for the production of a polypeptide
GB2216127A (en) * 1988-02-25 1989-10-04 Sandoz Ltd Endotoxin muteins
EP0358557A2 (en) * 1988-09-06 1990-03-14 Plant Genetic Systems, N.V. Plants transformed with a DNA sequence from bacillus thuringiensis lethal to lepidoptera
GB2246783A (en) * 1989-04-29 1992-02-12 Delta Biotechnology Ltd Fusion proteins containing n-terminal fragments of human serum albumin
GB2242681A (en) * 1990-04-05 1991-10-09 Ciba Geigy Ag Hirudin fragments
WO1991016433A1 (en) * 1990-04-26 1991-10-31 Plant Genetic Systems N.V. New bacillus thuringiensis strains and their genes encoding insecticidal toxins
GB2249099A (en) * 1990-09-26 1992-04-29 Squibb & Sons Inc Squalene synthetase
GB2249100A (en) * 1990-10-09 1992-04-29 Toyo Jozo Kk Expression of M-CSF deletion mutant polypeptides
WO1993015192A1 (en) * 1992-01-24 1993-08-05 Fmc Corporation Insecticidally effective peptides

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
EUR.J.BIOCHEM., Vol.213,1993, PAGES 121-127 *

Also Published As

Publication number Publication date
ZA953384B (en) 1996-01-12
GB9408466D0 (en) 1994-06-22
AU2264495A (en) 1995-11-16
GB2288807A (en) 1995-11-01
KR970702916A (en) 1997-06-10
HU9602959D0 (en) 1997-01-28
AU701101B2 (en) 1999-01-21
HUT76255A (en) 1997-07-28
EP0804571A1 (en) 1997-11-05
BR9507507A (en) 1997-09-02
GB9508298D0 (en) 1995-06-14
WO1995029235A1 (en) 1995-11-02
CN1147272A (en) 1997-04-09
CA2187920A1 (en) 1995-11-02
JP2000511761A (en) 2000-09-12

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20000424