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GB2120662B - New azepinoindoles their production and pharmaceutical compositions containing them - Google Patents

New azepinoindoles their production and pharmaceutical compositions containing them

Info

Publication number
GB2120662B
GB2120662B GB08312159A GB8312159A GB2120662B GB 2120662 B GB2120662 B GB 2120662B GB 08312159 A GB08312159 A GB 08312159A GB 8312159 A GB8312159 A GB 8312159A GB 2120662 B GB2120662 B GB 2120662B
Authority
GB
United Kingdom
Prior art keywords
azepinoindoles
new
production
pharmaceutical compositions
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08312159A
Other versions
GB2120662A (en
GB8312159D0 (en
Inventor
Fulvio Gadient
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of GB8312159D0 publication Critical patent/GB8312159D0/en
Publication of GB2120662A publication Critical patent/GB2120662A/en
Application granted granted Critical
Publication of GB2120662B publication Critical patent/GB2120662B/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
GB08312159A 1982-05-06 1983-05-04 New azepinoindoles their production and pharmaceutical compositions containing them Expired GB2120662B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH2806/82A CH649553A5 (en) 1982-05-06 1982-05-06 AZEPINOINDOLS AND METHOD FOR THE PRODUCTION THEREOF.

Publications (3)

Publication Number Publication Date
GB8312159D0 GB8312159D0 (en) 1983-06-08
GB2120662A GB2120662A (en) 1983-12-07
GB2120662B true GB2120662B (en) 1985-09-11

Family

ID=4242007

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08312159A Expired GB2120662B (en) 1982-05-06 1983-05-04 New azepinoindoles their production and pharmaceutical compositions containing them

Country Status (17)

Country Link
JP (1) JPS58203993A (en)
AU (1) AU1425683A (en)
BE (1) BE896590A (en)
CH (1) CH649553A5 (en)
DE (1) DE3315467A1 (en)
DK (1) DK199883A (en)
ES (1) ES8502440A1 (en)
FI (1) FI831475L (en)
FR (1) FR2526434A1 (en)
GB (1) GB2120662B (en)
HU (1) HU189275B (en)
IL (1) IL68576A0 (en)
IT (1) IT1197644B (en)
NL (1) NL8301552A (en)
PT (1) PT76632B (en)
SE (1) SE8302554L (en)
ZA (1) ZA833266B (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8500370A (en) * 1984-02-22 1985-09-16 Sandoz Ag DIAZEPINOINDOLS, METHODS FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM.
AU582564B2 (en) * 1985-02-20 1989-04-06 Sandoz Ltd. 2,3,4,5-tetrahydro-11-phenyl-1H-``1,4``diazepino``1,7-a`` indoles, their production and pharmaceutical compositions containing them
EP1319005A2 (en) * 2000-09-20 2003-06-18 PHARMACIA & UPJOHN COMPANY Substituted azepino[4,5-b]indoline derivatives
BR0211608A (en) * 2001-08-08 2006-04-04 Upjohn Co 1h-pyrido [4,3-b] therapeutic indoles
JP5188986B2 (en) * 2006-01-19 2013-04-24 アサーシス, インク. Thiophenyl and pyrrolylazepines as ligands for serotonin 5-HT2C receptors and uses thereof
WO2009089482A1 (en) 2008-01-11 2009-07-16 Albany Molecular Research, Inc. (1-azinone) -substituted pyridoindoles as mch antagonists
US8629158B2 (en) 2009-07-01 2014-01-14 Albany Molecular Research, Inc. Azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine MCH-1 antagonists, methods of making, and use thereof
US9073925B2 (en) 2009-07-01 2015-07-07 Albany Molecular Research, Inc. Azinone-substituted azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine MCH-1 antagonists, methods of making, and use thereof
WO2011003012A1 (en) 2009-07-01 2011-01-06 Albany Molecular Research, Inc. Azinone-substituted azapolycycle mch-1 antagonists, methods of making, and use thereof
WO2011003005A1 (en) 2009-07-01 2011-01-06 Albany Molecular Research, Inc. Azinone-substituted azepino[b]indole and pyrido-pyrrolo-azepine mch-1 antagonists, methods of making, and use thereof
US8993765B2 (en) 2010-12-21 2015-03-31 Albany Molecular Research, Inc. Tetrahydro-azacarboline MCH-1 antagonists, methods of making, and uses thereof
US8697700B2 (en) 2010-12-21 2014-04-15 Albany Molecular Research, Inc. Piperazinone-substituted tetrahydro-carboline MCH-1 antagonists, methods of making, and uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE12641T1 (en) * 1979-11-02 1985-04-15 Sandoz Ag AZEPININDOLS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.

Also Published As

Publication number Publication date
DK199883A (en) 1983-11-07
GB2120662A (en) 1983-12-07
HU189275B (en) 1986-06-30
SE8302554D0 (en) 1983-05-04
DE3315467A1 (en) 1983-11-17
FI831475L (en) 1983-11-07
ZA833266B (en) 1984-12-24
FR2526434A1 (en) 1983-11-10
DK199883D0 (en) 1983-05-04
AU1425683A (en) 1983-11-10
FI831475A0 (en) 1983-04-29
SE8302554L (en) 1983-11-07
PT76632A (en) 1983-06-01
BE896590A (en) 1983-10-28
GB8312159D0 (en) 1983-06-08
IT1197644B (en) 1988-12-06
ES522008A0 (en) 1985-01-01
CH649553A5 (en) 1985-05-31
NL8301552A (en) 1983-12-01
ES8502440A1 (en) 1985-01-01
IL68576A0 (en) 1983-09-30
JPS58203993A (en) 1983-11-28
PT76632B (en) 1986-01-27
IT8348232A0 (en) 1983-05-06

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee