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GB2176200B - Process for the preparation of heparin salts - Google Patents

Process for the preparation of heparin salts

Info

Publication number
GB2176200B
GB2176200B GB8613593A GB8613593A GB2176200B GB 2176200 B GB2176200 B GB 2176200B GB 8613593 A GB8613593 A GB 8613593A GB 8613593 A GB8613593 A GB 8613593A GB 2176200 B GB2176200 B GB 2176200B
Authority
GB
United Kingdom
Prior art keywords
preparation
heparin salts
heparin
salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
GB8613593A
Other versions
GB8613593D0 (en
GB2176200A (en
Inventor
Gyorgy Kerey
Janos Illes
Bela Stefko
Erzesbet Neszmelyi
Pal Gere
Istvan Zambo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT
Publication of GB8613593D0 publication Critical patent/GB8613593D0/en
Publication of GB2176200A publication Critical patent/GB2176200A/en
Application granted granted Critical
Publication of GB2176200B publication Critical patent/GB2176200B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
GB8613593A 1985-06-04 1986-06-04 Process for the preparation of heparin salts Expired - Fee Related GB2176200B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU852197A HU193769B (en) 1985-06-04 1985-06-04 Sodium-exchanging process for producing pharmaceutically acceptable heparinates applicable even for injections

Publications (3)

Publication Number Publication Date
GB8613593D0 GB8613593D0 (en) 1986-07-09
GB2176200A GB2176200A (en) 1986-12-17
GB2176200B true GB2176200B (en) 1990-01-24

Family

ID=10958239

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8613593A Expired - Fee Related GB2176200B (en) 1985-06-04 1986-06-04 Process for the preparation of heparin salts

Country Status (6)

Country Link
AT (1) AT397250B (en)
BE (1) BE904867A (en)
FR (1) FR2582657B1 (en)
GB (1) GB2176200B (en)
HU (1) HU193769B (en)
IT (1) IT1190124B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8702254D0 (en) * 1987-05-29 1987-05-29 Kabivitrum Ab NOVEL HEPARIN DERIVATIVES
US5264425A (en) * 1988-06-03 1993-11-23 Italfarmaco S.P.A. Glycosaminoglycan salts and pharmaceutical compositions containing them

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1013641B (en) * 1956-03-20 1957-08-14 Nordmark Werke Gmbh Method for purifying heparin
GB904112A (en) * 1958-12-19 1962-08-22 Roussel Uclaf Improvements in or relating to heparine and derivatives thereof
US2989438A (en) * 1958-12-29 1961-06-20 Roussel Uclaf Process of purifying heparin, and product produced therefrom
US3058884A (en) * 1959-09-14 1962-10-16 Abbott Lab Process for purifying heparin
US3160563A (en) * 1960-05-13 1964-12-08 Ormonoterapia Richter Spa Purification of heaprin
US3342683A (en) * 1964-02-25 1967-09-19 Taiyo Gyogyo Kabushiki Kaisha Heparin from whale tissue and method of preparing same
US3451996A (en) * 1968-02-12 1969-06-24 Thompson Farms Co Method for the preparation of heparin
US3817831A (en) * 1973-01-10 1974-06-18 Wilson Pharm & Chem Corp Process for production of alkali metal salt of heparin
GB2027728B (en) * 1978-08-08 1983-03-30 Choay Sa Physiologically acceptable heparin
IT1141263B (en) * 1980-02-29 1986-10-01 Italfarmaco Spa METHOD FOR THE PREPARATION OF CALCIUM HEPARINATE

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
'Methods in carbohydrate chemistry' vol *
v, pp 38-44 *

Also Published As

Publication number Publication date
IT8620676A0 (en) 1986-06-04
HU193769B (en) 1987-11-30
ATA144386A (en) 1993-07-15
FR2582657A1 (en) 1986-12-05
GB8613593D0 (en) 1986-07-09
FR2582657B1 (en) 1991-12-13
BE904867A (en) 1986-10-01
AT397250B (en) 1994-02-25
GB2176200A (en) 1986-12-17
IT8620676A1 (en) 1987-12-04
IT1190124B (en) 1988-02-10

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19960604