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GB201820685D0 - Synthesis of 8-chloroadenosine derivatives - Google Patents

Synthesis of 8-chloroadenosine derivatives

Info

Publication number
GB201820685D0
GB201820685D0 GBGB1820685.4A GB201820685A GB201820685D0 GB 201820685 D0 GB201820685 D0 GB 201820685D0 GB 201820685 A GB201820685 A GB 201820685A GB 201820685 D0 GB201820685 D0 GB 201820685D0
Authority
GB
United Kingdom
Prior art keywords
synthesis
chloroadenosine
derivatives
chloroadenosine derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1820685.4A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nucana PLC
Original Assignee
Nucana PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nucana PLC filed Critical Nucana PLC
Priority to GBGB1820685.4A priority Critical patent/GB201820685D0/en
Publication of GB201820685D0 publication Critical patent/GB201820685D0/en
Priority to PCT/GB2019/053609 priority patent/WO2020128469A1/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/02—Phosphorylation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/167—Purine radicals with ribosyl as the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GBGB1820685.4A 2018-12-19 2018-12-19 Synthesis of 8-chloroadenosine derivatives Ceased GB201820685D0 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
GBGB1820685.4A GB201820685D0 (en) 2018-12-19 2018-12-19 Synthesis of 8-chloroadenosine derivatives
PCT/GB2019/053609 WO2020128469A1 (en) 2018-12-19 2019-12-18 Synthesis of 8-chloroadenosine derivatives including nuc-9701

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1820685.4A GB201820685D0 (en) 2018-12-19 2018-12-19 Synthesis of 8-chloroadenosine derivatives

Publications (1)

Publication Number Publication Date
GB201820685D0 true GB201820685D0 (en) 2019-01-30

Family

ID=65147112

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB1820685.4A Ceased GB201820685D0 (en) 2018-12-19 2018-12-19 Synthesis of 8-chloroadenosine derivatives

Country Status (2)

Country Link
GB (1) GB201820685D0 (en)
WO (1) WO2020128469A1 (en)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1933588A (en) * 1987-12-21 1989-07-19 Nucleic Acid Research Institute Treatment of malignant tumors with 8-aminoadenosine 3',5'-cyclic phosphate and combinations of 8-aminoadeno- sine 3',5'-cyclic phosphate and 8-chloroadenosine 3',5'- cyclic phosphate
US6294522B1 (en) * 1999-12-03 2001-09-25 Cv Therapeutics, Inc. N6 heterocyclic 8-modified adenosine derivatives
GB201609602D0 (en) 2016-06-01 2016-07-13 Nucuna Biomed Ltd Chemical compounds

Also Published As

Publication number Publication date
WO2020128469A1 (en) 2020-06-25

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)