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GB2009121A - An Inorganic Support for an Enzyme Immobilisate - Google Patents

An Inorganic Support for an Enzyme Immobilisate

Info

Publication number
GB2009121A
GB2009121A GB7842743A GB7842743A GB2009121A GB 2009121 A GB2009121 A GB 2009121A GB 7842743 A GB7842743 A GB 7842743A GB 7842743 A GB7842743 A GB 7842743A GB 2009121 A GB2009121 A GB 2009121A
Authority
GB
United Kingdom
Prior art keywords
enzyme
immobilisate
modified
immobilisates
inorganic support
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB7842743A
Other versions
GB2009121B (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dynamit Nobel AG
Original Assignee
Dynamit Nobel AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19772749317 external-priority patent/DE2749317A1/en
Priority claimed from DE19782821889 external-priority patent/DE2821889A1/en
Application filed by Dynamit Nobel AG filed Critical Dynamit Nobel AG
Publication of GB2009121A publication Critical patent/GB2009121A/en
Application granted granted Critical
Publication of GB2009121B publication Critical patent/GB2009121B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/14—Enzymes or microbial cells immobilised on or in an inorganic carrier
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Inorganic Chemistry (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

The invention is concerned with enzyme immobilisates, and provides a modified inorganic element which is suitable for use as the supportive substrate of such an immobilisate. The modified element of the invention is in the form of a shaped element of amorphous silica treated with an alkoxy silane which contains an amino (including cyclic amino) group. The invention also provides a method of forming the modified element by treating the shaped element in a single stage with the alkoxy silane, and a method of forming an enzyme immobilisate by simply contacting the modified element with an enzyme solution. Enzyme immobilisates thus produced may be regenerated on the modified element, and may be used, for example when the enzyme is an acylase, in the selective enzymatic hydrolysis of N-acyl amino acids.
GB7842743A 1977-11-04 1978-11-01 Inorganic support for an enzyme immobilisate Expired GB2009121B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19772749317 DE2749317A1 (en) 1977-11-04 1977-11-04 Immobilising enzymes on amorphous silica carrier - pretreated with amino-alkoxy-silane, esp. for selective prodn. of L-amino acid from N-acyl cpds.
DE19782821889 DE2821889A1 (en) 1978-05-19 1978-05-19 Immobilising enzymes on amorphous silica carrier - pretreated with amino-alkoxy-silane, esp. for selective prodn. of L-amino acid from N-acyl cpds.

Publications (2)

Publication Number Publication Date
GB2009121A true GB2009121A (en) 1979-06-13
GB2009121B GB2009121B (en) 1982-04-15

Family

ID=25773021

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7842743A Expired GB2009121B (en) 1977-11-04 1978-11-01 Inorganic support for an enzyme immobilisate

Country Status (7)

Country Link
JP (1) JPS5473185A (en)
DK (1) DK492078A (en)
FR (1) FR2407937A1 (en)
GB (1) GB2009121B (en)
IT (1) IT1157387B (en)
NL (1) NL7810986A (en)
SE (1) SE7811369L (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3376223D1 (en) * 1982-07-29 1988-05-11 Shimadzu Corp A bioreactor and a process for the production thereof
DE3230736A1 (en) * 1982-08-18 1984-02-23 Herbert Prof. Dr. 8400 Regensburg Rupprecht ACTIVE SUBSTANCES BONDED TO SILICON DIOXIDE, METHOD FOR THEIR PRODUCTION AND THEIR USE
JPH01181790A (en) * 1988-01-18 1989-07-19 Toray Silicone Co Ltd Immobilization of bilogically active substance

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3669841A (en) * 1970-02-11 1972-06-13 Monsanto Co Attachment of enzymes to siliceous materials
NL7101680A (en) * 1970-02-11 1971-08-13
US3715278A (en) * 1970-02-11 1973-02-06 Monsanto Co Enzyme-polymer product attached to surface of siliceous materials thereof

Also Published As

Publication number Publication date
DK492078A (en) 1979-05-05
GB2009121B (en) 1982-04-15
JPS5473185A (en) 1979-06-12
FR2407937A1 (en) 1979-06-01
IT7851752A0 (en) 1978-11-02
IT1157387B (en) 1987-02-11
NL7810986A (en) 1979-05-08
SE7811369L (en) 1979-05-05

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee