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GB1361441A - Benzonaphthyridine derivatives - Google Patents

Benzonaphthyridine derivatives

Info

Publication number
GB1361441A
GB1361441A GB1398471A GB1398471A GB1361441A GB 1361441 A GB1361441 A GB 1361441A GB 1398471 A GB1398471 A GB 1398471A GB 1398471 A GB1398471 A GB 1398471A GB 1361441 A GB1361441 A GB 1361441A
Authority
GB
United Kingdom
Prior art keywords
cis
amino
amido
benzo
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1398471A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH708970A external-priority patent/CH527822A/de
Priority claimed from CH708670A external-priority patent/CH527196A/de
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of GB1361441A publication Critical patent/GB1361441A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms
    • C07D211/58Nitrogen atoms attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB1398471A 1970-05-13 1971-05-10 Benzonaphthyridine derivatives Expired GB1361441A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH708970A CH527822A (de) 1970-05-13 1970-05-13 Verfahren zur Herstellung neuer Benzonaphtyridin-Derivate
CH708670A CH527196A (de) 1970-05-13 1970-05-13 Verfahren zur Herstellung neuer Benzonaphthyridinderivate

Publications (1)

Publication Number Publication Date
GB1361441A true GB1361441A (en) 1974-07-24

Family

ID=25700728

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1398471A Expired GB1361441A (en) 1970-05-13 1971-05-10 Benzonaphthyridine derivatives

Country Status (14)

Country Link
JP (1) JPS5432799B1 (de)
AT (1) AT326674B (de)
CA (1) CA970377A (de)
CS (2) CS162753B2 (de)
DE (1) DE2123328A1 (de)
DK (1) DK134488B (de)
ES (1) ES391026A1 (de)
FI (1) FI52089C (de)
FR (1) FR2100649B1 (de)
GB (1) GB1361441A (de)
NL (1) NL7106502A (de)
PL (1) PL76913B1 (de)
SE (1) SE387640B (de)
SU (1) SU423296A3 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3899494A (en) * 1970-05-13 1975-08-12 Sandoz Ltd Substituted 6-phenyl benzo-naphthyridines
NL7314396A (de) * 1972-10-26 1974-05-01
BE880455A (fr) * 1979-01-22 1980-06-06 Sandoz Sa Compositions pharmaceutiques a base d'une benzo (c) (1,6) naphtyridine
ATE232864T1 (de) 1997-06-03 2003-03-15 Altana Pharma Ag Benzonaphthyridine
TR200201317T2 (tr) 1999-08-21 2002-11-21 Byk Gulden Lomberg Chemische Fabrik Gmbh Sinerjistik kombinasyon.
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
WO2004087211A2 (en) 2003-04-01 2004-10-14 Applied Research Systems Ars Holding N.V. Inhibitors of phosphodiesterases in infertility
MXPA06013162A (es) * 2004-05-12 2007-02-13 Pfizer Prod Inc Derivados de piperidina como antagonistas de neurocinina 1 y neurocinina 3.
EP2527360B1 (de) 2007-06-04 2015-10-28 Synergy Pharmaceuticals Inc. Für die Behandlung von gastrointestinalen Erkrankungen, Entzündungen, Krebs und anderen Erkrankungen geeignete Agonisten von Guanylatcyclase
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
ES2522968T3 (es) 2008-06-04 2014-11-19 Synergy Pharmaceuticals Inc. Agonistas de guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos
WO2010009319A2 (en) 2008-07-16 2010-01-21 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
EP3366698A1 (de) 2011-03-01 2018-08-29 Synergy Pharmaceuticals Inc. Guanylat-cyclase-c-agonisten
AU2014218599C1 (en) 2013-02-25 2018-09-06 Bausch Health Ireland Limited Guanylate cyclase receptor agonists for use in colonic cleansing
US9708367B2 (en) 2013-03-15 2017-07-18 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase and their uses
CA2905435A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
EA201592263A1 (ru) 2013-06-05 2016-05-31 Синерджи Фармасьютикалз, Инк. Ультрачистые агонисты гуанилатциклазы c, способ их получения и использования
WO2015021358A2 (en) 2013-08-09 2015-02-12 Dominique Charmot Compounds and methods for inhibiting phosphate transport
WO2020237096A1 (en) 2019-05-21 2020-11-26 Ardelyx, Inc. Combination for lowering serum phosphate in a patient

Also Published As

Publication number Publication date
CS162753B2 (de) 1975-07-15
DK134488B (da) 1976-11-15
FI52089B (de) 1977-02-28
FI52089C (fi) 1977-06-10
CA970377A (en) 1975-07-01
PL76913B1 (en) 1975-02-28
FR2100649A1 (de) 1972-03-24
NL7106502A (de) 1971-11-16
AT326674B (de) 1975-12-29
SU423296A3 (ru) 1974-04-05
DE2123328A1 (de) 1971-12-02
JPS5432799B1 (de) 1979-10-16
DK134488C (de) 1977-05-16
FR2100649B1 (de) 1974-08-30
SE387640B (sv) 1976-09-13
ATA412471A (de) 1975-03-15
CS167202B2 (de) 1976-04-29
ES391026A1 (es) 1974-04-01

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Legal Events

Date Code Title Description
PS Patent sealed
429A Application made for amendment of specification (sect. 29/1949)
429H Application (made) for amendment of specification now open to opposition (sect. 29/1949)
429D Case decided by the comptroller ** specification amended (sect. 29/1949)
SPA Amended specification published
PCNP Patent ceased through non-payment of renewal fee