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GB1276942A - Derivatives of chloramphenicol and thiamphenicol - Google Patents

Derivatives of chloramphenicol and thiamphenicol

Info

Publication number
GB1276942A
GB1276942A GB04254/70A GB1425470A GB1276942A GB 1276942 A GB1276942 A GB 1276942A GB 04254/70 A GB04254/70 A GB 04254/70A GB 1425470 A GB1425470 A GB 1425470A GB 1276942 A GB1276942 A GB 1276942A
Authority
GB
United Kingdom
Prior art keywords
phenyl
alkyl
thiamphenicol
chloramphenicol
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB04254/70A
Inventor
Hisao Akiyama
Tohru Mitani
Toshiaki Komatsu
Toyozoo Katsura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumitomo Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co Ltd filed Critical Sumitomo Chemical Co Ltd
Priority to GB04254/70A priority Critical patent/GB1276942A/en
Publication of GB1276942A publication Critical patent/GB1276942A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/12Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/02Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/22Separation; Purification; Stabilisation; Use of additives
    • C07C231/24Separation; Purification
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/46Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

1276942 Antimicrobial compositions SUMITOMO CHEMICAL CO Ltd 24 March 1970 14254/70 Heading ASB [Also in Division C2] Pharmaceutical compositions, having antimicrobial activity suitable for oral administration contain novel dichloroacetamides of the formula I: wherein R 1 is C 1 or Br; R 2 is H, Cl, Br, C 1-5 alkyl, phenyl or phenyl-C 1-5 alkyl; R 3 is Cl, Br, C 1-5 alkyl, phenyl or phenyl-C 1-5 alkyl; R 4 is NO 2 or CH 3 SO 2 ; and R 5 is H or -CO.C.R 1 R 2 R 3 ; provided that, in the case where R 4 is NO 2 , R 1 is Cl and R 2 and R 5 are each H, R 3 is not Cl or phenyl; together pharmaceutically acceptable carriers. The compositions may also contain chloramphenicol and thiamphenicol as further active ingredients.
GB04254/70A 1970-03-24 1970-03-24 Derivatives of chloramphenicol and thiamphenicol Expired GB1276942A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB04254/70A GB1276942A (en) 1970-03-24 1970-03-24 Derivatives of chloramphenicol and thiamphenicol

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB04254/70A GB1276942A (en) 1970-03-24 1970-03-24 Derivatives of chloramphenicol and thiamphenicol

Publications (1)

Publication Number Publication Date
GB1276942A true GB1276942A (en) 1972-06-07

Family

ID=10037823

Family Applications (1)

Application Number Title Priority Date Filing Date
GB04254/70A Expired GB1276942A (en) 1970-03-24 1970-03-24 Derivatives of chloramphenicol and thiamphenicol

Country Status (1)

Country Link
GB (1) GB1276942A (en)

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PLNP Patent lapsed through nonpayment of renewal fees