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GB1138530A - 2-phenylamino-2-oxazolines and their production - Google Patents

2-phenylamino-2-oxazolines and their production

Info

Publication number
GB1138530A
GB1138530A GB4399867A GB4399867A GB1138530A GB 1138530 A GB1138530 A GB 1138530A GB 4399867 A GB4399867 A GB 4399867A GB 4399867 A GB4399867 A GB 4399867A GB 1138530 A GB1138530 A GB 1138530A
Authority
GB
United Kingdom
Prior art keywords
formula
prepared
methoxy
reaction
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4399867A
Inventor
Hartmund Wollweber
Rudolf Hiltmann
Kurt Stoepel
Walter Puls
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of GB1138530A publication Critical patent/GB1138530A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/28—Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

1,138,530. N-Substituted 2-aminoxazoline. FARBENFABRIKEN BAYER A.G. 27 Sept., 1967 [27 Sept., 1966], No. 43998/67. Heading C2C. Novel compounds of formula or their tautomers where R is C 1-4 alkyl, C 1-4 alkoxy, or halogen, R<SP>1</SP> is methyl or ethyl and R<SP>11</SP> is H, C 1-4 alkyl, C 1-4 alkoxy, C 1-4 acyl or halogen, are prepared by (a) reaction of a compound of formula with ethanolamine or (b) by cyclization of a reactive ester of a compound of formula which may be prepared, optionally in situ either by reaction of an amine of formula with a #-haloethyl isocyanate or by reaction of a compound of formula with ethanolamine followed by formation of the reactive ester group. 2-Methoxy-6-methylphenyl isocyanide dichloride is prepared by chlorination of 2-methoxy-6- methylphenyl isocyanide prepared by action of phosgene on 2-methoxy-6-methyl-N-formyl analine.
GB4399867A 1966-09-27 1967-09-27 2-phenylamino-2-oxazolines and their production Expired GB1138530A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEF0050294 1966-09-27

Publications (1)

Publication Number Publication Date
GB1138530A true GB1138530A (en) 1969-01-01

Family

ID=7103684

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4399867A Expired GB1138530A (en) 1966-09-27 1967-09-27 2-phenylamino-2-oxazolines and their production

Country Status (5)

Country Link
AT (2) AT273107B (en)
BE (1) BE704393A (en)
DE (1) DE1670752A1 (en)
FR (1) FR1557684A (en)
GB (1) GB1138530A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4256755A (en) 1980-04-28 1981-03-17 E. I. Du Pont De Nemours & Company Method of using N-substituted dihydro-2-oxazolamines as analgesics

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1453703A (en) * 1972-12-28 1976-10-27 Science Union & Cie Substituted cyclopropylmethylamines processes for their preparation and pharmaceutical compositions containing them
CH623044A5 (en) * 1974-12-02 1981-05-15 Scherico Ltd Process for the preparation of novel anilino-2-oxazolines
JPS52111541A (en) * 1976-02-19 1977-09-19 Scherico Ltd Substituted ureido compound and medical composition containing it as active ingredient
FR2444673A1 (en) * 1978-12-20 1980-07-18 Science Union & Cie NOVEL TRIFLUOROETHYLAMINES, PROCESSES FOR OBTAINING SAME AND THEIR USE AS MEDICAMENTS

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4256755A (en) 1980-04-28 1981-03-17 E. I. Du Pont De Nemours & Company Method of using N-substituted dihydro-2-oxazolamines as analgesics

Also Published As

Publication number Publication date
AT273104B (en) 1969-08-11
AT273107B (en) 1969-08-11
BE704393A (en) 1968-03-27
FR1557684A (en) 1969-02-21
DE1670752A1 (en) 1970-12-23

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