GB1124838A - Phenyl-propylamine derivatives and process for preparing them - Google Patents
Phenyl-propylamine derivatives and process for preparing themInfo
- Publication number
- GB1124838A GB1124838A GB25044/66A GB2504466A GB1124838A GB 1124838 A GB1124838 A GB 1124838A GB 25044/66 A GB25044/66 A GB 25044/66A GB 2504466 A GB2504466 A GB 2504466A GB 1124838 A GB1124838 A GB 1124838A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- compound
- phenyl
- compounds
- hydrogen atom
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
- C07C217/62—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Compounds of the general Formula (I) <FORM:1124838/C2/1> (wherein R1 represents a phenyl, methoxyphenyl or 2-pyridyl group, R2 represents a hydrogen atom or a methyl group and R3 and R4 each represent a C1- 4 alkyl group) and their acid addition salts are prepared by standard methods, e.g. reducing a compound of the Formula (II) <FORM:1124838/C2/2> (wherein R represents a hydrogen atom) or a salt thereof, or condensing a compound of the Formula (III) <FORM:1124838/C2/3> with a compound of the Formula (IV) <FORM:1124838/C2/4> (wherein X represents <FORM:1124838/C2/5> and reducing the product, optionally followed in either case by salt formation. The preparation of starting materials of Formulae (II) and (IV) is described. The compounds of the invention are useful in the treatment of hypertonia, and may be administered in the form of pharmaceutical preparations containing them in association with a carrier.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEF0046262 | 1965-06-05 | ||
| DEF0047601 | 1965-11-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1124838A true GB1124838A (en) | 1968-08-21 |
Family
ID=25976808
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB25044/66A Expired GB1124838A (en) | 1965-06-05 | 1966-06-06 | Phenyl-propylamine derivatives and process for preparing them |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US3414578A (en) |
| AT (8) | AT275501B (en) |
| BE (1) | BE682140A (en) |
| BR (1) | BR6680181D0 (en) |
| CH (4) | CH464960A (en) |
| DE (2) | DE1493715A1 (en) |
| DK (1) | DK118407B (en) |
| ES (1) | ES327479A1 (en) |
| FI (1) | FI45184C (en) |
| GB (1) | GB1124838A (en) |
| IL (1) | IL25875A (en) |
| NL (1) | NL6607736A (en) |
| NO (1) | NO117860B (en) |
| SE (1) | SE348457B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4275198A (en) * | 1980-07-18 | 1981-06-23 | Carter-Wallace Inc. | Method for preparing basic dithienyl compounds |
-
1965
- 1965-06-05 DE DE19651493715 patent/DE1493715A1/en active Pending
- 1965-11-05 DE DE19651545869 patent/DE1545869A1/en active Pending
-
1966
- 1966-05-30 IL IL25875A patent/IL25875A/en unknown
- 1966-06-02 CH CH1468068A patent/CH464960A/en unknown
- 1966-06-02 CH CH1468468A patent/CH464962A/en unknown
- 1966-06-02 CH CH797366A patent/CH465645A/en unknown
- 1966-06-02 CH CH1468168A patent/CH464961A/en unknown
- 1966-06-02 ES ES0327479A patent/ES327479A1/en not_active Expired
- 1966-06-02 SE SE07542/66A patent/SE348457B/xx unknown
- 1966-06-02 FI FI661451A patent/FI45184C/en active
- 1966-06-03 AT AT169368A patent/AT275501B/en active
- 1966-06-03 NL NL6607736A patent/NL6607736A/xx unknown
- 1966-06-03 DK DK288666AA patent/DK118407B/en unknown
- 1966-06-03 AT AT01690/68A patent/AT277980B/en active
- 1966-06-03 BR BR180181/66A patent/BR6680181D0/en unknown
- 1966-06-03 AT AT169468A patent/AT272314B/en active
- 1966-06-03 AT AT168968A patent/AT272312B/en active
- 1966-06-03 AT AT168868A patent/AT272311B/en active
- 1966-06-03 AT AT529166A patent/AT272310B/en active
- 1966-06-03 AT AT169168A patent/AT275500B/en active
- 1966-06-03 AT AT169268A patent/AT272313B/en active
- 1966-06-04 NO NO163304A patent/NO117860B/no unknown
- 1966-06-06 BE BE682140D patent/BE682140A/xx unknown
- 1966-06-06 GB GB25044/66A patent/GB1124838A/en not_active Expired
- 1966-10-27 US US589816A patent/US3414578A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DK118407B (en) | 1970-08-17 |
| FI45184B (en) | 1971-12-31 |
| BE682140A (en) | 1966-12-06 |
| CH464962A (en) | 1968-11-15 |
| ES327479A1 (en) | 1967-10-16 |
| CH464960A (en) | 1968-11-15 |
| US3414578A (en) | 1968-12-03 |
| BR6680181D0 (en) | 1973-12-26 |
| AT272310B (en) | 1969-07-10 |
| AT272314B (en) | 1969-07-10 |
| CH465645A (en) | 1968-11-30 |
| AT277980B (en) | 1970-01-12 |
| DE1493715A1 (en) | 1969-06-19 |
| CH464961A (en) | 1968-11-15 |
| IL25875A (en) | 1970-04-20 |
| NO117860B (en) | 1969-10-06 |
| AT275501B (en) | 1969-10-27 |
| DE1545869A1 (en) | 1969-12-04 |
| AT272312B (en) | 1969-07-10 |
| AT272311B (en) | 1969-07-10 |
| AT272313B (en) | 1969-07-10 |
| AT275500B (en) | 1969-10-27 |
| NL6607736A (en) | 1966-12-06 |
| FI45184C (en) | 1972-04-10 |
| SE348457B (en) | 1972-09-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES483767A1 (en) | Alpha-(N-arylsulfonyl-L-argininamides, processes for their preparation and pharmaceutical compositions containing these substances. | |
| ATE110076T1 (en) | COMPOUNDS OF 1-AZABICYCLO(3.2.0)HEPT-2-EN-2-CARBONIC ACID. | |
| IL57577A0 (en) | 1,2-dihydroquinolin-2-one derivatives,process for their preparation and pharmaceutical compositions containing the same | |
| GB1106040A (en) | Novel benzdiaz[1,4]epine derivatives and a process for the manufacture thereof | |
| GB1048199A (en) | New bisalkanolamine derivatives and a process for their preparation | |
| GB1456627A (en) | Pyridobenzodiazepinones | |
| ES375203A1 (en) | Benzothiazepine derivatives | |
| GB1137764A (en) | Improvements in or relating to pharmacologically-active secondary amines | |
| GB1016071A (en) | New guanidine derivatives and process for preparing the same | |
| GB1434805A (en) | 5-phenoxy-4-amino pyrimidines | |
| GB993525A (en) | Substituted propanolamines and process for preparing the same | |
| GB1124838A (en) | Phenyl-propylamine derivatives and process for preparing them | |
| GB1421006A (en) | Imidazolidine derivatives | |
| GB1423954A (en) | Thionothiol-phosphoric acid esters process for their preparation and their use as insecticides and acaricides | |
| GB1434580A (en) | Disubstituted piperazines | |
| ES363591A1 (en) | beta-PHENETHYLAMINE DERIVATIVES AND A PROCESS FOR THE MANUFACTURE THEREOF | |
| GB1353508A (en) | Aminoisoquinolines | |
| GB1008849A (en) | Basically substituted triazolidines, processes for their manufacture and pharmaceutical preparations containing them | |
| GB1307256A (en) | Piperazine derivatives and a process for their preparation | |
| GB1067694A (en) | A process for the preparation of 2-alkyl-4-alkylamino-6-alkoxy-s-triazines | |
| GB1512653A (en) | Indazoles and the like | |
| GB1025577A (en) | Benzdiaz[1,4]epine derivatives and the manufacture thereof | |
| GB1073521A (en) | Indole derivatives | |
| GB1021522A (en) | 2-quinolone derivatives | |
| GB1089189A (en) | Ethers of -(2-pyridyl)benzyl alcohols |