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FR2969150B1 - NOVEL INDOLIC MOLECULES DEMONSTRATING ANTIBACTERIAL ACTIVITIES IN A VARIETY OF GRAM-NEGATIVE AND POSITIVE BACTERIA INCLUDING MULTI-DRUG-RESISTANT BACTERIA - Google Patents

NOVEL INDOLIC MOLECULES DEMONSTRATING ANTIBACTERIAL ACTIVITIES IN A VARIETY OF GRAM-NEGATIVE AND POSITIVE BACTERIA INCLUDING MULTI-DRUG-RESISTANT BACTERIA

Info

Publication number
FR2969150B1
FR2969150B1 FR1060825A FR1060825A FR2969150B1 FR 2969150 B1 FR2969150 B1 FR 2969150B1 FR 1060825 A FR1060825 A FR 1060825A FR 1060825 A FR1060825 A FR 1060825A FR 2969150 B1 FR2969150 B1 FR 2969150B1
Authority
FR
France
Prior art keywords
indolic
gram
drug
novel
variety
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR1060825A
Other languages
French (fr)
Other versions
FR2969150A1 (en
Inventor
Robert Dodd
Floriane Beaumard
Lionel Kiefer
Jean-Marie Pages
Jacqueline Chevalier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aix Marseille Universite
Centre National de la Recherche Scientifique CNRS
Original Assignee
Centre National de la Recherche Scientifique CNRS
Universite de la Mediterranee Aix Marseille II
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS, Universite de la Mediterranee Aix Marseille II filed Critical Centre National de la Recherche Scientifique CNRS
Priority to FR1060825A priority Critical patent/FR2969150B1/en
Priority to PCT/EP2011/073437 priority patent/WO2012084971A1/en
Publication of FR2969150A1 publication Critical patent/FR2969150A1/en
Application granted granted Critical
Publication of FR2969150B1 publication Critical patent/FR2969150B1/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR1060825A 2010-12-20 2010-12-20 NOVEL INDOLIC MOLECULES DEMONSTRATING ANTIBACTERIAL ACTIVITIES IN A VARIETY OF GRAM-NEGATIVE AND POSITIVE BACTERIA INCLUDING MULTI-DRUG-RESISTANT BACTERIA Expired - Fee Related FR2969150B1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FR1060825A FR2969150B1 (en) 2010-12-20 2010-12-20 NOVEL INDOLIC MOLECULES DEMONSTRATING ANTIBACTERIAL ACTIVITIES IN A VARIETY OF GRAM-NEGATIVE AND POSITIVE BACTERIA INCLUDING MULTI-DRUG-RESISTANT BACTERIA
PCT/EP2011/073437 WO2012084971A1 (en) 2010-12-20 2011-12-20 Indole derivatives as agents against gram-negative and gram-positive bacteria

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1060825A FR2969150B1 (en) 2010-12-20 2010-12-20 NOVEL INDOLIC MOLECULES DEMONSTRATING ANTIBACTERIAL ACTIVITIES IN A VARIETY OF GRAM-NEGATIVE AND POSITIVE BACTERIA INCLUDING MULTI-DRUG-RESISTANT BACTERIA

Publications (2)

Publication Number Publication Date
FR2969150A1 FR2969150A1 (en) 2012-06-22
FR2969150B1 true FR2969150B1 (en) 2013-07-26

Family

ID=43735134

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1060825A Expired - Fee Related FR2969150B1 (en) 2010-12-20 2010-12-20 NOVEL INDOLIC MOLECULES DEMONSTRATING ANTIBACTERIAL ACTIVITIES IN A VARIETY OF GRAM-NEGATIVE AND POSITIVE BACTERIA INCLUDING MULTI-DRUG-RESISTANT BACTERIA

Country Status (2)

Country Link
FR (1) FR2969150B1 (en)
WO (1) WO2012084971A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018165612A1 (en) 2017-03-10 2018-09-13 Rutgers, The State University Of New Jersey Bacterial efflux pump inhibitors
US11938114B2 (en) 2017-03-10 2024-03-26 Rutgers, The State University Of New Jersey Bacterial efflux pump inhibitors
WO2018165611A1 (en) * 2017-03-10 2018-09-13 Rutgers, The State University Of New Jersey Indole derivatives as efflux pump inhibitors
US11826357B2 (en) 2017-05-26 2023-11-28 Rutgers, The State University Of New Jersey Bacterial efflux pump inhibitors
WO2019005841A1 (en) 2017-06-26 2019-01-03 Rutgers, The State University Of New Jersey Therapeutic compounds and methods to treat infection
CN111349093B (en) * 2018-12-21 2021-07-02 汇瀚医疗科技有限公司 5, 6-bicyclic compounds as WNT signal pathway inhibitors and medical application thereof
WO2020125759A1 (en) * 2018-12-21 2020-06-25 汇瀚医疗科技有限公司 Compound as wnt signal pathway inhibitor and medical use thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6730684B1 (en) * 1999-10-08 2004-05-04 Affinium Pharmaceuticals, Inc. Fab I inhibitors
FR2809396B1 (en) * 2000-05-24 2005-10-14 Centre Nat Rech Scient NOVEL MOLECULES HAVING CALCIMIMETIC ACTIVITY AND THEIR METHOD OF PREPARATION
FR2912133B1 (en) * 2007-02-01 2009-04-24 Univ Grenoble 1 NOVEL INDOLIC DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND USES THEREOF IN PARTICULAR AS ANTIBACTERIANS

Also Published As

Publication number Publication date
FR2969150A1 (en) 2012-06-22
WO2012084971A1 (en) 2012-06-28

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Legal Events

Date Code Title Description
ST Notification of lapse

Effective date: 20140829