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FR2945806B1 - NOVEL IMIDAZO [1,2-A] PYRIDINE DERIVATIVES, PREPARATION METHOD, MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS AND USE IN PARTICULAR AS MET INHIBITORS - Google Patents

NOVEL IMIDAZO [1,2-A] PYRIDINE DERIVATIVES, PREPARATION METHOD, MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS AND USE IN PARTICULAR AS MET INHIBITORS

Info

Publication number
FR2945806B1
FR2945806B1 FR0902409A FR0902409A FR2945806B1 FR 2945806 B1 FR2945806 B1 FR 2945806B1 FR 0902409 A FR0902409 A FR 0902409A FR 0902409 A FR0902409 A FR 0902409A FR 2945806 B1 FR2945806 B1 FR 2945806B1
Authority
FR
France
Prior art keywords
medicaments
preparation
pharmaceutical compositions
pyridine derivatives
met inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0902409A
Other languages
French (fr)
Other versions
FR2945806A1 (en
Inventor
Dominique Damour
Conception Nemecek
Patrick Nemecek
Sylvie Wentzler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Sanofi Aventis France
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0902409A priority Critical patent/FR2945806B1/en
Application filed by Sanofi Aventis France filed Critical Sanofi Aventis France
Priority to BRPI0915924A priority patent/BRPI0915924A2/en
Priority to CN2009801365378A priority patent/CN102159559A/en
Priority to US13/003,604 priority patent/US20110257171A1/en
Priority to AU2009272517A priority patent/AU2009272517A1/en
Priority to PE2011000051A priority patent/PE20110572A1/en
Priority to EP09737061A priority patent/EP2318382A1/en
Priority to TW098124131A priority patent/TW201006839A/en
Priority to CA2730749A priority patent/CA2730749A1/en
Priority to ARP090102711A priority patent/AR072518A1/en
Priority to KR1020117003699A priority patent/KR20110039559A/en
Priority to EA201170223A priority patent/EA201170223A1/en
Priority to MX2011000675A priority patent/MX2011000675A/en
Priority to JP2011517979A priority patent/JP2011528338A/en
Priority to PCT/FR2009/051407 priority patent/WO2010007317A1/en
Priority to UY0001031997A priority patent/UY31997A/en
Publication of FR2945806A1 publication Critical patent/FR2945806A1/en
Priority to IL210689A priority patent/IL210689A0/en
Priority to ZA2011/00429A priority patent/ZA201100429B/en
Priority to CL2011000116A priority patent/CL2011000116A1/en
Priority to CO11004611A priority patent/CO6331467A2/en
Priority to MA33619A priority patent/MA32565B1/en
Application granted granted Critical
Publication of FR2945806B1 publication Critical patent/FR2945806B1/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR0902409A 2008-07-18 2009-05-19 NOVEL IMIDAZO [1,2-A] PYRIDINE DERIVATIVES, PREPARATION METHOD, MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS AND USE IN PARTICULAR AS MET INHIBITORS Expired - Fee Related FR2945806B1 (en)

Priority Applications (21)

Application Number Priority Date Filing Date Title
FR0902409A FR2945806B1 (en) 2009-05-19 2009-05-19 NOVEL IMIDAZO [1,2-A] PYRIDINE DERIVATIVES, PREPARATION METHOD, MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS AND USE IN PARTICULAR AS MET INHIBITORS
PCT/FR2009/051407 WO2010007317A1 (en) 2008-07-18 2009-07-16 Novel imidazo[1,2-a]pyridine derivatives, method for the preparation thereof, use thereof as medicaments, pharmaceutical compositions and novel use in particular as met inhibitors
JP2011517979A JP2011528338A (en) 2008-07-18 2009-07-16 Novel imidazo [1,2-a] pyridine derivatives, process for their preparation, their use as pharmaceuticals, pharmaceutical compositions, and new uses, especially as MET inhibitors
AU2009272517A AU2009272517A1 (en) 2008-07-18 2009-07-16 Novel imidazo[1,2-a]pyridine derivatives, method for the preparation thereof, use thereof as medicaments, pharmaceutical compositions and novel use in particular as MET inhibitors
CN2009801365378A CN102159559A (en) 2008-07-18 2009-07-16 Novel imidazo[1,2-a]pyridine derivatives, method for the preparation thereof, use thereof as medicaments, pharmaceutical compositions and novel use in particular as met inhibitors
EP09737061A EP2318382A1 (en) 2008-07-18 2009-07-16 Novel imidazo[1,2-a]pyridine derivatives, method for the preparation thereof, use thereof as medicaments, pharmaceutical compositions and novel use in particular as met inhibitors
TW098124131A TW201006839A (en) 2008-07-18 2009-07-16 Novel imidazo[1,2-a]pyridine derivatives, process for the preparation thereof, use thereof as medicaments, pharmaceutical compositions and novel use, in particular as MET inhibitors
EA201170223A EA201170223A1 (en) 2008-07-18 2009-07-16 NEW IMIDAZO DERIVATIVES [1,2-a] PYRIDINE, METHOD FOR THEIR PRODUCTION, THEIR APPLICATION AS A MEDICINE, PHARMACEUTICAL COMPOSITIONS AND A NEW APPLICATION, PARTICULAR AS INHIBITORS
ARP090102711A AR072518A1 (en) 2008-07-18 2009-07-16 IMIDAZO DERIVATIVES [1,2-A] PIRIDINE, ITS PREPARATION PROCEDURE, PHARMACEUTICAL COMPOSITIONS AND ITS PARTICULAR USE AS MET INHIBITORS. "
KR1020117003699A KR20110039559A (en) 2008-07-18 2009-07-16 Novel imidazo[1,2-a]pyridine derivatives, method for the preparation thereof, use thereof as medicaments, pharmaceutical compositions and novel use in particular as met inhibitors
BRPI0915924A BRPI0915924A2 (en) 2008-07-18 2009-07-16 imidazo [1,2-a] pyridine derivatives, their preparation process, their application as medicinal products, pharmaceutical compositions and new use notably as metal
MX2011000675A MX2011000675A (en) 2008-07-18 2009-07-16 Novel imidazo[1,2-a]pyridine derivatives, method for the preparation thereof, use thereof as medicaments, pharmaceutical compositions and novel use in particular as met inhibitors.
US13/003,604 US20110257171A1 (en) 2008-07-18 2009-07-16 Novel imidazo[1,2-a]pyridine derivatives, method for the preparation thereof, use thereof as medicaments, pharmaceutical compositions and novel use in particular as met inhibitors
PE2011000051A PE20110572A1 (en) 2008-07-18 2009-07-16 DERIVATIVES OF IMIDAZO [1,2-a] PYRIDINE AS MET INHIBITORS
CA2730749A CA2730749A1 (en) 2008-07-18 2009-07-16 Novel imidazo[1,2-a]pyridine derivatives, method for the preparation thereof, use thereof as medicaments, pharmaceutical compositions and novel use in particular as met inhibitors
UY0001031997A UY31997A (en) 2008-07-18 2009-07-17 NEW DERIVATIVES OF IMIDAZO [1,2-A] PIRIDINA, AND ITS NEW USES AS INHIBITORS OF MET.
IL210689A IL210689A0 (en) 2008-07-18 2011-01-16 Novel imidazo [1, 2 - a] pyridine derivatives, method for the preparation thereof, use thereof as medicaments, pharmaceutical compositions and novel use in particular as met inhibitors
ZA2011/00429A ZA201100429B (en) 2008-07-18 2011-01-17 Novel imidazo [1,2-a]pyrimidine derivatives,method for the preparation thereof,use thereof as medicaments,pharmaceutical compositions and novel use in particular as met inhibitors
CL2011000116A CL2011000116A1 (en) 2008-07-18 2011-01-18 Compounds derived from imidazo [1,2-a] pyridine; preparation procedure; pharmaceutical composition; intermediate compounds; and use in the treatment of cancer.
CO11004611A CO6331467A2 (en) 2008-07-18 2011-01-18 NEW IMIDAZO DERIVATIVES (1,2-A) PIRIDINA, ITS PREPARATION PROCEDURE, ITS APPLICATION AS MEDICINES, PHARMACEUTICAL COMPOSITIONS AND NEW USE IN PARTICULARLY AS MET INHIBITORS
MA33619A MA32565B1 (en) 2008-07-18 2011-02-15 NOVEL IMIDAZO [1,2-a] PYRIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, THEIR USE AS MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS AND NOVEL USE IN PARTICULAR AS MET INHIBITORS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0902409A FR2945806B1 (en) 2009-05-19 2009-05-19 NOVEL IMIDAZO [1,2-A] PYRIDINE DERIVATIVES, PREPARATION METHOD, MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS AND USE IN PARTICULAR AS MET INHIBITORS

Publications (2)

Publication Number Publication Date
FR2945806A1 FR2945806A1 (en) 2010-11-26
FR2945806B1 true FR2945806B1 (en) 2013-04-05

Family

ID=41338623

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0902409A Expired - Fee Related FR2945806B1 (en) 2008-07-18 2009-05-19 NOVEL IMIDAZO [1,2-A] PYRIDINE DERIVATIVES, PREPARATION METHOD, MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS AND USE IN PARTICULAR AS MET INHIBITORS

Country Status (1)

Country Link
FR (1) FR2945806B1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117924279B (en) * 2024-03-18 2024-07-16 中山大学 MELK inhibitor and application thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2785157A (en) * 1952-11-05 1957-03-12 Eastman Kodak Co Benzothiazoleazoaniline compounds
GB9919778D0 (en) * 1999-08-21 1999-10-27 Zeneca Ltd Chemical compounds
PL357099A1 (en) * 2000-02-07 2004-07-12 Abbott Gmbh & Co.Kg 2-benzothiazolyl urea derivatives and their use as protein kinase inhibitors
PA8792501A1 (en) * 2007-08-09 2009-04-23 Sanofi Aventis NEW DERIVATIVES OF 6-TRIAZOLOPIRIDACINA-SULFANIL BENZOTIAZOL AND BENCIMIDAZOL, ITS PREPARATION PROCEDURE, ITS APPLICATION AS MEDICATIONS, PHARMACEUTICAL COMPOSITIONS AND NEW MAIN USE AS MET INHIBITORS.
PT2212323E (en) * 2007-10-17 2012-11-27 Novartis Ag Imidazo [1,2-a] pyridine derivatives useful as alk inhibitors

Also Published As

Publication number Publication date
FR2945806A1 (en) 2010-11-26

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Year of fee payment: 7

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Effective date: 20170131