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FR2830017B1 - Materiau compose d'au moins un polymere biodegradable et de cyclodextrines - Google Patents

Materiau compose d'au moins un polymere biodegradable et de cyclodextrines

Info

Publication number
FR2830017B1
FR2830017B1 FR0112456A FR0112456A FR2830017B1 FR 2830017 B1 FR2830017 B1 FR 2830017B1 FR 0112456 A FR0112456 A FR 0112456A FR 0112456 A FR0112456 A FR 0112456A FR 2830017 B1 FR2830017 B1 FR 2830017B1
Authority
FR
France
Prior art keywords
cyclodextrins
biodegradable polymer
biodegradable
polymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0112456A
Other languages
English (en)
Other versions
FR2830017A1 (fr
Inventor
Ruxandra Gref
Patrick Couvreur
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Original Assignee
Centre National de la Recherche Scientifique CNRS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS filed Critical Centre National de la Recherche Scientifique CNRS
Priority to FR0112456A priority Critical patent/FR2830017B1/fr
Priority to CA002461421A priority patent/CA2461421A1/fr
Priority to JP2003530753A priority patent/JP2005503476A/ja
Priority to PCT/FR2002/003321 priority patent/WO2003027169A1/fr
Priority to US10/490,417 priority patent/US20050043481A1/en
Priority to EP02781387A priority patent/EP1440114A1/fr
Publication of FR2830017A1 publication Critical patent/FR2830017A1/fr
Application granted granted Critical
Publication of FR2830017B1 publication Critical patent/FR2830017B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5146Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153Polyesters, e.g. poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/593Polyesters, e.g. PLGA or polylactide-co-glycolide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G81/00Macromolecular compounds obtained by interreacting polymers in the absence of monomers, e.g. block polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Nanotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Optics & Photonics (AREA)
  • Biomedical Technology (AREA)
  • Polymers & Plastics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR0112456A 2001-09-27 2001-09-27 Materiau compose d'au moins un polymere biodegradable et de cyclodextrines Expired - Fee Related FR2830017B1 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
FR0112456A FR2830017B1 (fr) 2001-09-27 2001-09-27 Materiau compose d'au moins un polymere biodegradable et de cyclodextrines
CA002461421A CA2461421A1 (fr) 2001-09-27 2002-09-27 Materiau compose d'au moins un polymere biodegradable et de cyclodextrines
JP2003530753A JP2005503476A (ja) 2001-09-27 2002-09-27 生分解可能ポリマーおよびシクロデキストリン含有材料
PCT/FR2002/003321 WO2003027169A1 (fr) 2001-09-27 2002-09-27 Materiau compose d'au moins un polymere biodegradable et de cyclodextrines
US10/490,417 US20050043481A1 (en) 2001-09-27 2002-09-27 Material consisting of at least a biodegradable polymer and cyclodextrins
EP02781387A EP1440114A1 (fr) 2001-09-27 2002-09-27 Materiau compose d'au moins un polymere biodegradable et de cyclodextrines

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0112456A FR2830017B1 (fr) 2001-09-27 2001-09-27 Materiau compose d'au moins un polymere biodegradable et de cyclodextrines

Publications (2)

Publication Number Publication Date
FR2830017A1 FR2830017A1 (fr) 2003-03-28
FR2830017B1 true FR2830017B1 (fr) 2005-11-04

Family

ID=8867681

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0112456A Expired - Fee Related FR2830017B1 (fr) 2001-09-27 2001-09-27 Materiau compose d'au moins un polymere biodegradable et de cyclodextrines

Country Status (6)

Country Link
US (1) US20050043481A1 (fr)
EP (1) EP1440114A1 (fr)
JP (1) JP2005503476A (fr)
CA (1) CA2461421A1 (fr)
FR (1) FR2830017B1 (fr)
WO (1) WO2003027169A1 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005320469A (ja) * 2004-05-11 2005-11-17 Idemitsu Kosan Co Ltd ポリカーボネート樹脂組成物及び成形品
CA2597716A1 (fr) * 2005-02-15 2006-08-24 Elan Pharma International Limited Formulations aerosol et injectables de nanoparticules de benzodiazepine
ES2277743B2 (es) 2005-06-02 2008-12-16 Universidade De Santiago De Compostela Nanoparticulas que comprenden quitosano y ciclodextrina.
EP1808181A1 (fr) * 2006-01-17 2007-07-18 B. Braun Melsungen Ag Conjugués comprenant du polysaccharide et de la cyclodextrine
US20070232567A1 (en) * 2006-03-28 2007-10-04 Curtis Wright Formulations Of Low Dose Non-Steroidal Anti-Inflammatory Drugs And Beta-Cyclodextrin
CA2647348A1 (fr) * 2006-03-28 2007-10-04 Javelin Pharmaceuticals, Inc. Formulations de diclofenac et de cyclodextrine beta a faible dosage
ES2310122B1 (es) * 2007-04-20 2009-10-30 Instituto Cientifico Y Tecnologico De Navarra, S.A Nanoparticulas que comprenden una ciclodextrina y una molecula biologicamente activa y sus aplicaciones.
ITMI20071173A1 (it) * 2007-06-11 2008-12-12 Univ Degli Studi Milano Polimeri iperramificati a base di ciclodestrine e poli(amidoammine) per il rilascio controllato di farmaci insolubili
US20090060860A1 (en) * 2007-08-31 2009-03-05 Eva Almenar Beta-cyclodextrins as nucleating agents for poly(lactic acid)
ES2392375T3 (es) * 2007-12-13 2012-12-10 Kyushu University, National University Corporation Nanopartículas que contienen fármacos que comprenden pioglitazona
EP2444532B1 (fr) 2009-06-18 2014-07-23 Omikenshi Co., Ltd. Fibres contenant de l'iode et de l'amylose, leur procédé de production et leur utilisation
SG11201504922WA (en) * 2012-12-21 2015-07-30 Advanced Medical Frontier Co Ltd Composition and food or drink
WO2017090524A1 (fr) * 2015-11-27 2017-06-01 シャープ株式会社 Procédé de gravure humide et procédé de fabrication d'un dispositif à semi-conducteur
CN112126075B (zh) * 2020-09-23 2022-06-07 兰州大学第二医院 一种可降解的形状记忆聚合物及其制备方法、4d打印可降解下肢血管支架及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5462990A (en) * 1990-10-15 1995-10-31 Board Of Regents, The University Of Texas System Multifunctional organic polymers
US5321064A (en) * 1992-05-12 1994-06-14 Regents Of The University Of Minnesota Compositions of biodegradable natural and synthetic polymers
US5543158A (en) * 1993-07-23 1996-08-06 Massachusetts Institute Of Technology Biodegradable injectable nanoparticles
FR2732026B1 (fr) * 1995-03-21 1997-06-06 Roquette Freres Procede pour ameliorer la compatibilite reciproque de polymeres
AU5610198A (en) * 1996-12-19 1998-07-15 Penn State Research Foundation, The Compounds and methods for treating and preventing bacterial and viral disease
US6613703B1 (en) * 2000-04-27 2003-09-02 Kimberly-Clark Worldwide, Inc. Thermoplastic nonwoven web chemically reacted with a cyclodextrin compound

Also Published As

Publication number Publication date
US20050043481A1 (en) 2005-02-24
WO2003027169A1 (fr) 2003-04-03
CA2461421A1 (fr) 2003-04-03
EP1440114A1 (fr) 2004-07-28
FR2830017A1 (fr) 2003-03-28
JP2005503476A (ja) 2005-02-03

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Legal Events

Date Code Title Description
ST Notification of lapse

Effective date: 20070531