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FR2506264A1 - FLEXIBLE POUCH CONTAINER FOR LYOPHILIZING LIQUID AND METHOD OF USE - Google Patents

FLEXIBLE POUCH CONTAINER FOR LYOPHILIZING LIQUID AND METHOD OF USE

Info

Publication number
FR2506264A1
FR2506264A1 FR8110069A FR8110069A FR2506264A1 FR 2506264 A1 FR2506264 A1 FR 2506264A1 FR 8110069 A FR8110069 A FR 8110069A FR 8110069 A FR8110069 A FR 8110069A FR 2506264 A1 FR2506264 A1 FR 2506264A1
Authority
FR
France
Prior art keywords
liquid
container
neck
wall
utilization
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8110069A
Other languages
French (fr)
Other versions
FR2506264B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to FR8110069A priority Critical patent/FR2506264A1/en
Priority to EP82400943A priority patent/EP0065469B1/en
Priority to AT82400943T priority patent/ATE36645T1/en
Priority to DE8282400943T priority patent/DE3278928D1/en
Publication of FR2506264A1 publication Critical patent/FR2506264A1/en
Application granted granted Critical
Publication of FR2506264B1 publication Critical patent/FR2506264B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/10—Bag-type containers
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B5/00—Drying solid materials or objects by processes not involving the application of heat
    • F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
    • F26B5/06—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Vaporization, Distillation, Condensation, Sublimation, And Cold Traps (AREA)
  • Drying Of Solid Materials (AREA)

Abstract

1. Method of conditioning and utilization of a liquid involving its lyophilization, wherein : - in order to contain the liquid in the conditioning stage and in the utilization stage, there is employed one and the same container constructed in the form of a flexible bag having a first and a second wall (1) bonded along their external contour (82) so as to form an envelope and a rigid neck (6) which extends through said envelope in leak-tight manner, thus forming an opening of the bag ; - in the conditioning stage : the liquid container is partially filled with liquid, the container is placed in a substantially horizontal position on a support of the lyophilization device in such a manner as to ensure that a first wall and the neck are in contact with said support, the two walls being maintained in relatively spaced relation solely by the neck in the vicinity of this latter, said second wall is lifted in its remaining non-spaced portion so as to ensure that the liquid which rests substantially on said first wall has a free surface which is not in contact with the second wall, the liquid is cooled to freezing point, it is reheated in a vacuum while discharging through the neck the steam extracted by sublimation of the frozen product, the opening of the neck is hermetically sealed-off, said container is stored until direct utilization of the conditioned liquid ; - and in the utilization stage : the liquid is reconstituted by injecting water into the container without impairing leak-tightness, the reconstituted liquid is withdrawn from said container.
FR8110069A 1981-05-20 1981-05-20 FLEXIBLE POUCH CONTAINER FOR LYOPHILIZING LIQUID AND METHOD OF USE Granted FR2506264A1 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
FR8110069A FR2506264A1 (en) 1981-05-20 1981-05-20 FLEXIBLE POUCH CONTAINER FOR LYOPHILIZING LIQUID AND METHOD OF USE
EP82400943A EP0065469B1 (en) 1981-05-20 1982-05-19 Method for preparation of a liquid to be lyophilized and use of said liquid
AT82400943T ATE36645T1 (en) 1981-05-20 1982-05-19 METHOD OF FREEZE DRYING OF LIQUIDS AND ITS APPLICATION.
DE8282400943T DE3278928D1 (en) 1981-05-20 1982-05-19 Method for preparation of a liquid to be lyophilized and use of said liquid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8110069A FR2506264A1 (en) 1981-05-20 1981-05-20 FLEXIBLE POUCH CONTAINER FOR LYOPHILIZING LIQUID AND METHOD OF USE

Publications (2)

Publication Number Publication Date
FR2506264A1 true FR2506264A1 (en) 1982-11-26
FR2506264B1 FR2506264B1 (en) 1985-01-04

Family

ID=9258695

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8110069A Granted FR2506264A1 (en) 1981-05-20 1981-05-20 FLEXIBLE POUCH CONTAINER FOR LYOPHILIZING LIQUID AND METHOD OF USE

Country Status (4)

Country Link
EP (1) EP0065469B1 (en)
AT (1) ATE36645T1 (en)
DE (1) DE3278928D1 (en)
FR (1) FR2506264A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4973327A (en) * 1989-11-01 1990-11-27 Cryopharm Blood bag for lyophilization
DE4405965C2 (en) * 1994-02-24 1997-08-07 Bernd Hansen Infusion container with two connections
US5871110A (en) * 1996-09-13 1999-02-16 Grimard; Jean-Pierre Transfer assembly for a medicament container having a splashless valve
US5925029A (en) * 1997-09-25 1999-07-20 Becton, Dickinson And Company Method and apparatus for fixing a connector assembly onto a vial with a crimp cap
US6090093A (en) * 1997-09-25 2000-07-18 Becton Dickinson And Company Connector assembly for a vial having a flexible collar
US6213994B1 (en) 1997-09-25 2001-04-10 Becton Dickinson France, S.A. Method and apparatus for fixing a connector assembly onto a vial
US6382442B1 (en) 1998-04-20 2002-05-07 Becton Dickinson And Company Plastic closure for vials and other medical containers
US6681946B1 (en) 1998-02-26 2004-01-27 Becton, Dickinson And Company Resealable medical transfer set
US6003566A (en) * 1998-02-26 1999-12-21 Becton Dickinson And Company Vial transferset and method
US6378714B1 (en) 1998-04-20 2002-04-30 Becton Dickinson And Company Transferset for vials and other medical containers
GB2361709A (en) * 2000-04-26 2001-10-31 Moorlodge Biotech Ventures Ltd Vessel for transporting micro organisms

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2642866A (en) * 1951-02-03 1953-06-23 Arthur F Smith Blood container and method of making the same
GB730148A (en) * 1953-08-04 1955-05-18 Armour & Co Improvements in or relating to closures for lyophilization containers
CH323689A (en) * 1953-07-31 1957-08-15 Antoine Rieutord Louis Marie Process for controlling the desiccation of a vacuum body and device for implementing this process
FR2281276A1 (en) * 1974-08-06 1976-03-05 Behringwerke Ag METHOD OF MANUFACTURING A CONTAINER FOR LYOPHILIZED MATERIAL FIRM UNDER STERILE CONDITIONS
FR2284842A1 (en) * 1974-09-11 1976-04-09 Nestle Sa IMPROVEMENT PROVIDES LYOPHILIZATION OF SOLID, LIQUID OR PASTE PRODUCTS

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1428373A (en) * 1972-06-12 1976-03-17 Smith & Nephew Res Containers
JPS5841964Y2 (en) * 1979-05-18 1983-09-22 テルモ株式会社 plastic pharmaceutical liquid containers

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2642866A (en) * 1951-02-03 1953-06-23 Arthur F Smith Blood container and method of making the same
CH323689A (en) * 1953-07-31 1957-08-15 Antoine Rieutord Louis Marie Process for controlling the desiccation of a vacuum body and device for implementing this process
GB730148A (en) * 1953-08-04 1955-05-18 Armour & Co Improvements in or relating to closures for lyophilization containers
FR2281276A1 (en) * 1974-08-06 1976-03-05 Behringwerke Ag METHOD OF MANUFACTURING A CONTAINER FOR LYOPHILIZED MATERIAL FIRM UNDER STERILE CONDITIONS
FR2284842A1 (en) * 1974-09-11 1976-04-09 Nestle Sa IMPROVEMENT PROVIDES LYOPHILIZATION OF SOLID, LIQUID OR PASTE PRODUCTS

Also Published As

Publication number Publication date
ATE36645T1 (en) 1988-09-15
FR2506264B1 (en) 1985-01-04
EP0065469A3 (en) 1983-06-22
DE3278928D1 (en) 1988-09-29
EP0065469B1 (en) 1988-08-24
EP0065469A2 (en) 1982-11-24

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Legal Events

Date Code Title Description
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