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FR2433517A1 - Derives conjugues marques par chimioluminescence au phtallhydrazide - Google Patents

Derives conjugues marques par chimioluminescence au phtallhydrazide

Info

Publication number
FR2433517A1
FR2433517A1 FR7918974A FR7918974A FR2433517A1 FR 2433517 A1 FR2433517 A1 FR 2433517A1 FR 7918974 A FR7918974 A FR 7918974A FR 7918974 A FR7918974 A FR 7918974A FR 2433517 A1 FR2433517 A1 FR 2433517A1
Authority
FR
France
Prior art keywords
phtallhydrazide
chemoluminescence
conjugated derivatives
marked
derivatives marked
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7918974A
Other languages
English (en)
Other versions
FR2433517B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Corp
Original Assignee
Miles Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Miles Laboratories Inc filed Critical Miles Laboratories Inc
Publication of FR2433517A1 publication Critical patent/FR2433517A1/fr
Application granted granted Critical
Publication of FR2433517B1 publication Critical patent/FR2433517B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30—Phthalazines
    • C07D237/32—Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/807—Hapten conjugated with peptide or protein

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Luminescent Compositions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

La présente invention concerne des dérivés conjugués, marqués par chimioluminescence. Ces dérivés répondent à la formule :
FR7918974A 1978-07-24 1979-07-23 Derives conjugues marques par chimioluminescence au phtallhydrazide Granted FR2433517A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/927,621 US4334069A (en) 1978-07-24 1978-07-24 Chemiluminescent phthalhydrazide-labeled hapten conjugates

Publications (2)

Publication Number Publication Date
FR2433517A1 true FR2433517A1 (fr) 1980-03-14
FR2433517B1 FR2433517B1 (fr) 1983-07-08

Family

ID=25455009

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7918974A Granted FR2433517A1 (fr) 1978-07-24 1979-07-23 Derives conjugues marques par chimioluminescence au phtallhydrazide

Country Status (7)

Country Link
US (1) US4334069A (fr)
JP (1) JPS5518996A (fr)
CA (1) CA1137975A (fr)
DE (1) DE2928048A1 (fr)
FR (1) FR2433517A1 (fr)
GB (3) GB2041921B (fr)
IL (1) IL57644A (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997022594A1 (fr) * 1995-12-15 1997-06-26 Phytera Symbion Aps Banques combinatoires

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX153322A (es) * 1979-05-23 1986-09-12 Miles Lab Dispositivo analitico quimioluminiscente mejorado para detectar un componente en una muestra de liquidos corporales
EP0046742B1 (fr) * 1980-08-25 1984-06-27 KabiVitrum AB Substrats peptidiques pour la détermination de l'activité de protéases
US4537718A (en) * 1982-10-26 1985-08-27 Columbia University In The City Of New York Impermeant spectroscopic probes
US4943636A (en) * 1984-03-10 1990-07-24 Cetus Corporation Certain pyridyl-di-sulfide-alkylenecarbonxylate-ortho-nitro-phenylsulfonic acid esters useful for coupling biological materials
US4954637A (en) * 1984-03-10 1990-09-04 Cetus Corporation Certain maleimide-N-alkylenecarboxylate-ortho-nitrobenzenesulfonic acid esters and derivatives useful for coupling biological materials
US4665181A (en) * 1984-05-17 1987-05-12 Pennwalt Corporation Anti-inflammatory phthalazinones
US5422266A (en) * 1984-12-31 1995-06-06 University Of Georgia Research Foundation, Inc. Recombinant DNA vectors capable of expressing apoaequorin
DE3679690D1 (de) * 1985-03-19 1991-07-18 Abbott Lab Diagnostische probe, die mikroperoxidase verwendet.
US4743541A (en) * 1985-07-17 1988-05-10 Mast Immunosystems, Inc. Luminescent substrate preparation and its use in specific binding assays
IT1211749B (it) * 1986-09-24 1989-11-03 Bayer Aktinegesellschaft Procedimento per la polimerizzazio ne di derivati acrilici
DE3844954C2 (de) * 1988-02-20 1998-07-16 Hoechst Ag Spezielle chemilumineszierende Acridinderivate und ihre Verwendung in Lumineszenzimmunoassays
US6002007A (en) * 1988-02-20 1999-12-14 Dade Behring Marburg Gmbh Special chemiluminescent acridine derivatives and the use thereof in luminescence immunoassays
DE3900648A1 (de) * 1989-01-11 1990-07-12 Boehringer Mannheim Gmbh Neue cobalamin-saeurehydrazide und davon abgeleitete cobalamin-konjugate
US5068227A (en) * 1989-01-18 1991-11-26 Cyclex, Inc. Cyclodextrins as carriers
EP0562306B1 (fr) * 1992-03-06 1995-08-30 Zdzislaw Dr. Fiutowski Composition pharmaceutique ayant une activité antivirale et antibactérielle
CH683965A5 (it) * 1993-02-19 1994-06-30 Limad Marketing Exp & Imp Composti della classe dei ftalidrazidici come sostanza attiva in agenti antinfiammatori ed antitossici.
US5395752A (en) * 1993-03-19 1995-03-07 Ciba Corning Diagnostics Corp. Long emission wavelength chemiluminescent compounds and their use in test assays
AU679008B2 (en) * 1993-05-06 1997-06-19 Chiron Diagnostics Corporation Mixed luminescent conjugate test assays
DE19623814C2 (de) * 1995-06-15 1999-02-11 Lab Molecular Biophotonics Verfahren und Vorrichtung zur analytischen Bestimmung von 5-Hydroxyindolen oder Catecholaminen
US6297239B1 (en) 1997-10-08 2001-10-02 Merck & Co., Inc. Inhibitors of prenyl-protein transferase
CN105348202B (zh) * 2015-12-24 2018-03-30 北京百灵威科技有限公司 一种以邻苯二甲酰肼为原料制备异鲁米诺的方法
CN114853738B (zh) * 2022-04-29 2022-11-29 广州中医药大学(广州中医药研究院) 一种鲁米诺衍生物及其制备方法与应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4011219A (en) * 1975-03-28 1977-03-08 Chugai Seiyaku Kabushiki Kaisha Phthalazine derivatives and salts thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2453578A (en) * 1944-02-19 1948-11-09 American Cyanamid Co Preparation of chemiluminescent composition of matter
US3520872A (en) * 1967-03-24 1970-07-21 Upjohn Co Process for labelling purine and pyrimidine containing compounds
US3875011A (en) * 1972-11-06 1975-04-01 Syva Co Enzyme immunoassays with glucose-6-phosphate dehydrogenase
US4065354A (en) * 1974-10-10 1977-12-27 Syva Company Lysozyme conjugates for enzyme immunoassays
IN142734B (fr) * 1975-04-28 1977-08-20 Miles Lab
US4181650A (en) * 1975-08-25 1980-01-01 Maier Charles L Jr Procedure for the assay of pharmacologically immunologically and biochemically active compounds in biological fluids
GB1578275A (en) 1977-06-14 1980-11-05 Maier C Procedure for the assay of pharmacologically immunologically and biochemically active compounds in biological fluids

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4011219A (en) * 1975-03-28 1977-03-08 Chugai Seiyaku Kabushiki Kaisha Phthalazine derivatives and salts thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
EXBK/76 *
EXBK/78 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997022594A1 (fr) * 1995-12-15 1997-06-26 Phytera Symbion Aps Banques combinatoires

Also Published As

Publication number Publication date
GB2041920A (en) 1980-09-17
CA1137975A (fr) 1982-12-21
GB2041921A (en) 1980-09-17
IL57644A (en) 1983-03-31
GB2026159A (en) 1980-01-30
GB2041920B (en) 1982-12-08
IL57644A0 (en) 1979-10-31
GB2041921B (en) 1982-12-08
DE2928048C2 (fr) 1988-11-10
JPS5518996A (en) 1980-02-09
GB2026159B (en) 1983-03-02
US4334069A (en) 1982-06-08
FR2433517B1 (fr) 1983-07-08
DE2928048A1 (de) 1980-02-07

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