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FR2414054A2 - Nouveaux derives 17a-acetyleniques de l'androst 4-ene, leur procede de preparation et leur application comme medicaments - Google Patents

Nouveaux derives 17a-acetyleniques de l'androst 4-ene, leur procede de preparation et leur application comme medicaments

Info

Publication number
FR2414054A2
FR2414054A2 FR7800405A FR7800405A FR2414054A2 FR 2414054 A2 FR2414054 A2 FR 2414054A2 FR 7800405 A FR7800405 A FR 7800405A FR 7800405 A FR7800405 A FR 7800405A FR 2414054 A2 FR2414054 A2 FR 2414054A2
Authority
FR
France
Prior art keywords
contg
hydroxy
alkynyl
steroid
pharmaceuticals
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7800405A
Other languages
English (en)
Other versions
FR2414054B2 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Priority to FR7800405A priority Critical patent/FR2414054A2/fr
Priority to SE7801152A priority patent/SE7801152L/xx
Priority to IL54070A priority patent/IL54070A0/xx
Priority to JP1666678A priority patent/JPS53103462A/ja
Priority to OA56411A priority patent/OA05890A/fr
Priority to US05/878,907 priority patent/US4168306A/en
Priority to GR55501A priority patent/GR71701B/el
Priority to AT121078A priority patent/AT357280B/de
Priority to NL7801919A priority patent/NL7801919A/xx
Priority to AU33468/78A priority patent/AU514875B2/en
Priority to LU79100A priority patent/LU79100A1/fr
Priority to CA297,372A priority patent/CA1114366A/fr
Priority to DK075778A priority patent/DK160559C/da
Priority to PT67685A priority patent/PT67685B/fr
Priority to HU78RO964A priority patent/HU175028B/hu
Priority to ES78467158A priority patent/ES467158A1/es
Priority to CH193178A priority patent/CH633714A5/fr
Priority to PH20808A priority patent/PH13909A/en
Priority to IE386/78A priority patent/IE46562B1/en
Priority to DE19782807611 priority patent/DE2807611A1/de
Priority to GB6984/78A priority patent/GB1598023A/en
Publication of FR2414054A2 publication Critical patent/FR2414054A2/fr
Application granted granted Critical
Publication of FR2414054B2 publication Critical patent/FR2414054B2/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
    • C07J1/004—Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
    • C07J1/0048—Alkynyl derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)

Abstract

L'INVENTION A POUR OBJET LES COMPOSES REPONDANT A LA FORMULE I DU BREVET PRINCIPAL: (CF DESSIN DANS BOPI) DANS LAQUELLE R REPRESENTE UN RADICAL ALCOYLE SATURE OU INSATURE RENFERMANT DE 1 A 12ATOMES DE CARBONE, ET LES TRAITS POINTILLES DANS LE CYCLE A REPRESENTENT UNE DOUBLE LIAISON EVENTUELLE EN 1(2) A CONDITION QUE SI LE CYCLE A PORTE UNE SEULE DOUBLE LIAISON EN 4(5), R NE REPRESENTE PAS UN RADICAL METHYLE. L'INVENTION A EGALEMENT POUR OBJET UN PROCEDE DE PREPARATION DES COMPOSES DE FORMULE I. LES COMPOSES DE FORMULE I PRESENTENT D'INTERESSANTES PROPRIETES PHARMACOLOGIQUES QUI JUSTIFIENT LEUR UTILISATION EN THERAPEUTIQUE.
FR7800405A 1977-02-22 1978-01-09 Nouveaux derives 17a-acetyleniques de l'androst 4-ene, leur procede de preparation et leur application comme medicaments Granted FR2414054A2 (fr)

Priority Applications (21)

Application Number Priority Date Filing Date Title
FR7800405A FR2414054A2 (fr) 1978-01-09 1978-01-09 Nouveaux derives 17a-acetyleniques de l'androst 4-ene, leur procede de preparation et leur application comme medicaments
SE7801152A SE7801152L (sv) 1977-02-22 1978-01-31 Sett att framstella 17alfa-acetylen-derivat av androst-4-en
IL54070A IL54070A0 (en) 1977-02-22 1978-02-17 17 -acetylene derivatives of androst-4-ene, process for preparing them and pharmaceutical compositions
JP1666678A JPS53103462A (en) 1977-02-22 1978-02-17 11androstaa44enee17alphaaacetylene derivative process for preparing same and pharmaceutical composition
OA56411A OA05890A (fr) 1977-02-22 1978-02-17 Procédé de préparation de dérivés 17a-acétyléniques de l'androst 4-ène.
US05/878,907 US4168306A (en) 1977-02-22 1978-02-17 17α-Acetylenic-Δ4 -androstenes
AT121078A AT357280B (de) 1977-02-22 1978-02-20 Verfahren zur herstellung von 17alpha- -alkinyl-androst-4-enderivaten
GR55501A GR71701B (fr) 1977-02-22 1978-02-20
CA297,372A CA1114366A (fr) 1977-02-22 1978-02-21 PROCEDE DE PREPARATION DE DERIVES 17.alpha.-ACETYLENIQUES DE L'ANDROST 4-ENE
LU79100A LU79100A1 (fr) 1977-02-22 1978-02-21 Procede de preparation de derives 17alpha-acetyleniques de l'androst 4-ene
NL7801919A NL7801919A (nl) 1977-02-22 1978-02-21 17-(alpha)-acetyleen derivaten van androst-u-een, werkwijze ter bereiding van deze verbindingen en kern toepassing in farmaceutische preparaten.
DK075778A DK160559C (da) 1977-02-22 1978-02-21 Analogifremgangsmaade til fremstilling af 17alpfa-acetylen-derivater af androstenforbindelser
PT67685A PT67685B (fr) 1977-02-22 1978-02-21 Procede de preparation de derives 17alpha-acetyleniques del'androst-4-ene
HU78RO964A HU175028B (hu) 1977-02-22 1978-02-21 Sposob poluchenija proizvodnykh 17-al'fa-alkinil-androst-4-enov
ES78467158A ES467158A1 (es) 1977-02-22 1978-02-21 Un procedimiento de preparacion de derivados 17 alfa-aceti- lenicos del androst-4-eno.
AU33468/78A AU514875B2 (en) 1977-02-22 1978-02-21 17-acetylene derivatives of androst-4-ene
CH193178A CH633714A5 (fr) 1977-02-22 1978-02-22 Derives 17alpha-acetyleniques de l'androst 4-ene, procede de prepararation et compositions pharmaceutiques.
PH20808A PH13909A (en) 1977-02-22 1978-02-22 17(-acetylenic-androstenes,the pharmaceutical composition
IE386/78A IE46562B1 (en) 1977-02-22 1978-02-22 17a-acetylene derivatives of androst-4-ene,processes for preparing them and pharmaceutical compositions containing them
DE19782807611 DE2807611A1 (de) 1977-02-22 1978-02-22 17alpha-acetylenische derivate des androst-4-ens, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen
GB6984/78A GB1598023A (en) 1977-02-22 1978-02-22 17-acetylene derivatives of androst-4-ene processes for preparing them and pharmaceutical compositions containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7800405A FR2414054A2 (fr) 1978-01-09 1978-01-09 Nouveaux derives 17a-acetyleniques de l'androst 4-ene, leur procede de preparation et leur application comme medicaments

Publications (2)

Publication Number Publication Date
FR2414054A2 true FR2414054A2 (fr) 1979-08-03
FR2414054B2 FR2414054B2 (fr) 1982-10-08

Family

ID=9203212

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7800405A Granted FR2414054A2 (fr) 1977-02-22 1978-01-09 Nouveaux derives 17a-acetyleniques de l'androst 4-ene, leur procede de preparation et leur application comme medicaments

Country Status (1)

Country Link
FR (1) FR2414054A2 (fr)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1265821A (fr) * 1958-01-24 1961-07-07 British Drug Houses Ltd Procédé de fabrication de dérivés 21-alkylés des 17beta-hydroxy-17alpha-prégn-20-ynes
US3127314A (en) * 1964-03-31 Method of reducing hyperlipemia by
FR2740798A1 (fr) * 1995-11-02 1997-05-09 Lee Wen Yuan Agencement de forme modulaire pour des structures en beton

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3127314A (en) * 1964-03-31 Method of reducing hyperlipemia by
FR1265821A (fr) * 1958-01-24 1961-07-07 British Drug Houses Ltd Procédé de fabrication de dérivés 21-alkylés des 17beta-hydroxy-17alpha-prégn-20-ynes
FR2740798A1 (fr) * 1995-11-02 1997-05-09 Lee Wen Yuan Agencement de forme modulaire pour des structures en beton

Also Published As

Publication number Publication date
FR2414054B2 (fr) 1982-10-08

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