FR2329277A1 - Thiazolinylcetobenzimidazoles et leurs derives, utiles comme agents anti-viraux - Google Patents

Thiazolinylcetobenzimidazoles et leurs derives, utiles comme agents anti-viraux

Info

Publication number: FR2329277A1
Authority: FR; France
Prior art keywords: thiazolinylcetobenzimidazoles; derivatives; useful; viral agents; viral
Prior art date: 1975-10-28
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

FR7626027A

Other languages

English (en)

Other versions

FR2329277B1 (fr

Inventor

Charles Johnson Paget

James Wesley Chamberlin

James Howard Wikel

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Eli Lilly and Co

Original Assignee

Eli Lilly and Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1975-10-28

Filing date

1976-08-27

Publication date

1977-05-27

1976-08-27 Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co

1977-05-27 Publication of FR2329277A1 publication Critical patent/FR2329277A1/fr

1978-11-17 Application granted granted Critical

1978-11-17 Publication of FR2329277B1 publication Critical patent/FR2329277B1/fr

Status Granted legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Virology (AREA)
Chemical Kinetics & Catalysis (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

FR7626027A 1975-10-28 1976-08-27 Thiazolinylcetobenzimidazoles et leurs derives, utiles comme agents anti-viraux Granted FR2329277A1 (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US62601475A	1975-10-28	1975-10-28
US06/002,836 US4216313A (en)	1975-10-28	1979-01-12	Antiviral thiazinyl benzimidazoles

Publications (2)

Publication Number	Publication Date
FR2329277A1 true FR2329277A1 (fr)	1977-05-27
FR2329277B1 FR2329277B1 (fr)	1978-11-17

Family

ID=26670950

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FR7626027A Granted FR2329277A1 (fr)	1975-10-28	1976-08-27	Thiazolinylcetobenzimidazoles et leurs derives, utiles comme agents anti-viraux

Country Status (11)

Country	Link
US (2)	US4150028A (fr)
JP (1)	JPS5253861A (fr)
AT (1)	AT360006B (fr)
AU (1)	AU509008B2 (fr)
BE (1)	BE845642A (fr)
CA (1)	CA1076582A (fr)
CH (1)	CH629203A5 (fr)
DE (1)	DE2638553C2 (fr)
FR (1)	FR2329277A1 (fr)
GB (1)	GB1562823A (fr)
NL (1)	NL7609411A (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4420479A (en) *	1982-04-08	1983-12-13	Eli Lilly And Company	Olefinic benzimidazoles, formulations, and antiviral methods
IL68297A (en) *	1982-04-08	1986-09-30	Lilly Co Eli	Process for removing 1-sulfonyl groups from 2-amino-5(6)-substituted benzimidazoles
US4463181A (en) *	1982-04-08	1984-07-31	Eli Lilly And Company	Process for removing sulfonyl groups from benzimidazole isomers
US4434288A (en) *	1982-04-08	1984-02-28	Eli Lilly And Company	Preparation of substituted 1-thiazinyl or 1-thiazolyl-2-aminobenzimidazoles
US4492708A (en) *	1982-09-27	1985-01-08	Eli Lilly And Company	Antiviral benzimidazoles
JP2787539B2 (ja) *	1993-02-26	1998-08-20	松森　　昭	ウイルス性疾患の予防または治療剤
US5693661A (en) *	1995-06-07	1997-12-02	Eli Lilly And Company	Anti-viral compounds
US7538107B2 (en)	2006-08-15	2009-05-26	Wyeth	Oxazinan-2-one derivatives useful as PR modulators
WO2008021309A1 (fr) *	2006-08-15	2008-02-21	Wyeth	Dérivés d'imidazolidin-2-one utiles en tant que modulateurs pr
WO2008021338A2 (fr) *	2006-08-15	2008-02-21	Wyeth	Dérivés d'oxazolidone tricycliques utiles en tant que modulateurs du récepteur de la progestérone
US7649007B2 (en) *	2006-08-15	2010-01-19	Wyeth Llc	Oxazolidine derivatives as PR modulators
US20080045560A1 (en) *	2006-08-15	2008-02-21	Wyeth	Pyrrolidine and related derivatives useful as PR modulators
TW200815428A (en) *	2006-08-15	2008-04-01	Wyeth Corp	Oxazolidone derivatives as PR modulators
SG144809A1 (en)	2007-01-11	2008-08-28	Millipore U K Ltd	Benzimidazole compounds and their use as chromatographic ligands
WO2017040993A1 (fr) *	2015-09-03	2017-03-09	The Arizona Board Of Regents On Behalf Of The University Of Arizona	Petites molécules inhibitrices de dyrk1a et leurs utilisations

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS4842875B1 (fr) *	1969-01-29	1973-12-14
US3749717A (en) *	1971-05-04	1973-07-31	Squibb & Sons Inc	Thiazolinyl and thiazinyl derivatives of benzimidazoles
US3825537A (en) *	1972-02-28	1974-07-23	Squibb & Sons Inc	1-thiazolin-2-yl(or thiazin-2-yl)-2-aminobenzimidazoles and derivatives thereof
US4008243A (en) *	1975-11-19	1977-02-15	Eli Lilly And Company	Antiviral thiazolinyl or thiazinyl benzimidazole esters

1976
- 1976-07-22 CA CA257,583A patent/CA1076582A/fr not_active Expired
- 1976-08-19 AU AU16983/76A patent/AU509008B2/en not_active Expired
- 1976-08-24 GB GB35134/76A patent/GB1562823A/en not_active Expired
- 1976-08-24 NL NL7609411A patent/NL7609411A/xx not_active Application Discontinuation
- 1976-08-26 DE DE2638553A patent/DE2638553C2/de not_active Expired
- 1976-08-26 AT AT636476A patent/AT360006B/de not_active IP Right Cessation
- 1976-08-26 CH CH1085576A patent/CH629203A5/de not_active IP Right Cessation
- 1976-08-27 FR FR7626027A patent/FR2329277A1/fr active Granted
- 1976-08-27 BE BE1007587A patent/BE845642A/fr not_active IP Right Cessation
- 1976-10-26 JP JP51129304A patent/JPS5253861A/ja active Pending
1977
- 1977-02-16 US US05/769,358 patent/US4150028A/en not_active Expired - Lifetime
1979
- 1979-01-12 US US06/002,836 patent/US4216313A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
BE845642A (fr)	1977-02-28
AU509008B2 (en)	1980-04-17
DE2638553C2 (de)	1985-09-12
AT360006B (de)	1980-12-10
DE2638553A1 (de)	1977-05-12
AU1698376A (en)	1978-02-23
US4150028A (en)	1979-04-17
CA1076582A (fr)	1980-04-29
CH629203A5 (de)	1982-04-15
JPS5253861A (en)	1977-04-30
GB1562823A (en)	1980-03-19
FR2329277B1 (fr)	1978-11-17
ATA636476A (de)	1980-05-15
US4216313A (en)	1980-08-05
NL7609411A (nl)	1977-05-02

Publication	Publication Date	Title
BE847034A (fr)	1977-01-31	Derives de piperidyl-triazine.
BE844737A (fr)	1977-01-31	Derives benzylideniques
SE7606181L (sv)	1976-12-04	Hoftledsprotes
FR2304342A1 (fr)	1976-10-15	Derives de la quinolone
SE7601274L (sv)	1976-08-16	Isoxazolylbensamid-derivat
NL7606655A (nl)	1976-12-21	Imidylbenzeendi- en -tricarbonzuurderivaten.
BE839839A (fr)	1976-09-20	Derives de la quinolone
FR2329277A1 (fr)	1977-05-27	Thiazolinylcetobenzimidazoles et leurs derives, utiles comme agents anti-viraux
BE845643A (fr)	1977-02-28	Esters de thiazolinyl- ou thiazonyl-benzimidazoles, utiles comme agents anti-viraux
NL7613659A (nl)	1977-06-10	Hydroxybenzylmalonzuurderivaten.
BE848534A (fr)	1977-05-20	Agents antiadhesifs,
NL7609137A (nl)	1977-02-22	Fenoxyalkylcarbonzuurderivaten.
FR2295955A1 (fr)	1976-07-23	Derives morpholoniques et leur application comme fongicides
NL7607993A (nl)	1977-01-19	Ortho-aminobutyrofenonderivaten.
SE7608393L (sv)	1977-01-26	Lenkrulle
FR2318853A1 (fr)	1977-02-18	Derives de dodecatetraene, leur preparation et leurs utilisations
BE865843A (fr)	1978-10-10	4-alcoylthio-2-trifluoromethylalcanesulfonanilides et leurs derives
FR2330687A1 (fr)	1977-06-03	2-halogeno-5-trichloromethyl-1,3,4-thiadiazoles-utiles comme fongicides
SE7613797L (sv)	1977-06-23	Cyproheptadinderivat
BE847149A (fr)	1977-04-12	Derives de thiazolinylamino-piperidine,
FR2322122A1 (fr)	1977-03-25	Derives de tetracyclotetradecene
SE418632B (sv)	1981-06-15	Sneppgangjern av korslenkstyp
BE845052A (fr)	1977-02-10	Derives de guanidine
SE7608519L (sv)	1977-02-07	Morfantridin-derivat
FR2303547A1 (fr)	1976-10-08	Derives de l'isoquinoleine

Legal Events

Date	Code	Title	Description
1987-06-19	ST	Notification of lapse