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FR2276049A1 - Bacteriostatic 5-substd.-oxolinic acids - prepn. by nitration of oxolinic acid and derivs, and opt redn. to the amino cpds. (NO260176) - Google Patents

Bacteriostatic 5-substd.-oxolinic acids - prepn. by nitration of oxolinic acid and derivs, and opt redn. to the amino cpds. (NO260176)

Info

Publication number
FR2276049A1
FR2276049A1 FR7519545A FR7519545A FR2276049A1 FR 2276049 A1 FR2276049 A1 FR 2276049A1 FR 7519545 A FR7519545 A FR 7519545A FR 7519545 A FR7519545 A FR 7519545A FR 2276049 A1 FR2276049 A1 FR 2276049A1
Authority
FR
France
Prior art keywords
oxolinic
cpds
nitration
opt
derivs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7519545A
Other languages
French (fr)
Other versions
FR2276049B1 (en
Inventor
Judit Frank
Zoltan Meszaros
Vera Kovacs-Nee-Mindler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chinoin Private Co Ltd
Original Assignee
Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt filed Critical Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Publication of FR2276049A1 publication Critical patent/FR2276049A1/en
Application granted granted Critical
Publication of FR2276049B1 publication Critical patent/FR2276049B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Quinolin-4-one-3-carboxylic acid derivs. of formula: (where X is NO2, NH2, acylamino, diacylamino, alkylamino, dialkylamino; R and R' are H or alkyl) and their salts are prepd. by nitration of cpds. of formula (II), then opt. reducing the product to give the amino cpds. which are then optionally alkylated or acylated or esterified). The cpds. are stated to be new but are not claimed. The cpds. are bacteriostatic agents for oral admin. with low toxicity.
FR7519545A 1974-06-25 1975-06-23 Bacteriostatic 5-substd.-oxolinic acids - prepn. by nitration of oxolinic acid and derivs, and opt redn. to the amino cpds. (NO260176) Granted FR2276049A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HUCI1485A HU170681B (en) 1974-06-25 1974-06-25

Publications (2)

Publication Number Publication Date
FR2276049A1 true FR2276049A1 (en) 1976-01-23
FR2276049B1 FR2276049B1 (en) 1979-08-17

Family

ID=10994523

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7519545A Granted FR2276049A1 (en) 1974-06-25 1975-06-23 Bacteriostatic 5-substd.-oxolinic acids - prepn. by nitration of oxolinic acid and derivs, and opt redn. to the amino cpds. (NO260176)

Country Status (10)

Country Link
AT (1) AT341526B (en)
CS (1) CS188379B1 (en)
DD (1) DD118431A1 (en)
DK (1) DK137927B (en)
ES (1) ES438816A1 (en)
FI (1) FI751869A (en)
FR (1) FR2276049A1 (en)
HU (1) HU170681B (en)
NO (1) NO142783C (en)
SU (1) SU582766A3 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994002145A2 (en) * 1992-07-22 1994-02-03 Genelabs Technologies, Inc. 2-aryl-4-quinolones as antitumor compounds
US5571822A (en) * 1994-09-30 1996-11-05 The University Of North Carolina At Chapel Hill Antitumor compounds

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994002145A2 (en) * 1992-07-22 1994-02-03 Genelabs Technologies, Inc. 2-aryl-4-quinolones as antitumor compounds
WO1994002145A3 (en) * 1992-07-22 1994-04-28 Genelabs Tech Inc 2-aryl-4-quinolones as antitumor compounds
US5571822A (en) * 1994-09-30 1996-11-05 The University Of North Carolina At Chapel Hill Antitumor compounds

Also Published As

Publication number Publication date
DK137927B (en) 1978-06-05
DK137927C (en) 1978-10-30
ES438816A1 (en) 1977-02-01
FR2276049B1 (en) 1979-08-17
FI751869A (en) 1975-12-26
NO142783C (en) 1980-10-15
NO752224L (en) 1975-12-30
NO142783B (en) 1980-07-07
SU582766A3 (en) 1977-11-30
HU170681B (en) 1977-08-28
AT341526B (en) 1978-02-10
CS188379B1 (en) 1979-03-30
ATA478375A (en) 1977-06-15
DK287075A (en) 1975-12-26
DD118431A1 (en) 1976-03-05

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Legal Events

Date Code Title Description
ST Notification of lapse