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FR2195425A1 - Biological products from animal organs - by homogenization proteolysis, acid purification and ultra filtration - Google Patents

Biological products from animal organs - by homogenization proteolysis, acid purification and ultra filtration

Info

Publication number
FR2195425A1
FR2195425A1 FR7329254A FR7329254A FR2195425A1 FR 2195425 A1 FR2195425 A1 FR 2195425A1 FR 7329254 A FR7329254 A FR 7329254A FR 7329254 A FR7329254 A FR 7329254A FR 2195425 A1 FR2195425 A1 FR 2195425A1
Authority
FR
France
Prior art keywords
degrees
homogenization
proteolysis
animal organs
biological products
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7329254A
Other languages
French (fr)
Other versions
FR2195425B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MANGANARO DOMENICO
Original Assignee
MANGANARO DOMENICO
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MANGANARO DOMENICO filed Critical MANGANARO DOMENICO
Publication of FR2195425A1 publication Critical patent/FR2195425A1/en
Application granted granted Critical
Publication of FR2195425B1 publication Critical patent/FR2195425B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/22—Urine; Urinary tract, e.g. kidney or bladder; Intraglomerular mesangial cells; Renal mesenchymal cells; Adrenal gland
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/26—Lymph; Lymph nodes; Thymus; Spleen; Splenocytes; Thymocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37—Digestive system
    • A61K35/407—Liver; Hepatocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/50—Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Pregnancy & Childbirth (AREA)
  • Reproductive Health (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Prepn. of liquid compsns. from animal organs in which the conc. of active components is similar to that in the unextracted organ by homogenization of the organ at ca. 40 degrees C with no addn. of liquid or other agents, proteolysing the homogenate with proteases, e.g. pancreatic enzymes at 37-38 degrees C and pH 7.5, filtering, purifying the filtrate by heating at acid pH, e.g. to 60 degrees C for 2 hrs., decantation after 24 hrs. at 5 degrees C, filtration, pH adjustment to that for parenteral use, e.g. 5.5, standing for a further 24 hr. at 5 degrees C and finally ultrafiltration. Prods. prepd. in this way from liver, placenta, kidney and spleen arc suitable for chemical use, and are cheap to make as no solvents are used.
FR7329254A 1972-08-10 1973-08-09 Biological products from animal organs - by homogenization proteolysis, acid purification and ultra filtration Granted FR2195425A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT5211672 1972-08-10

Publications (2)

Publication Number Publication Date
FR2195425A1 true FR2195425A1 (en) 1974-03-08
FR2195425B1 FR2195425B1 (en) 1977-02-25

Family

ID=11276400

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7329254A Granted FR2195425A1 (en) 1972-08-10 1973-08-09 Biological products from animal organs - by homogenization proteolysis, acid purification and ultra filtration

Country Status (1)

Country Link
FR (1) FR2195425A1 (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2835292A1 (en) * 1977-08-16 1979-03-01 Cellorgan Sa Lab PROCESS FOR PRODUCING DEFIBRINIZED AND FREEZE-DRIED PLACENTA CELLS
DE3008900A1 (en) * 1979-03-09 1980-09-18 Nestle Sa METHOD FOR PRODUCING A PURIFIED PROTEIN HYDROLYSATE
FR2484651A1 (en) * 1980-06-16 1981-12-18 Tena Lab Morrith Sa Gui Aminoacid and peptide soln. of animal origin e.g. milk - used to treat nerve cell disorders, obtd. by extn. of centrifugation to remove fatty constituents, adjustment of pH and removal of sediment
EP0095682A3 (en) * 1982-05-28 1984-06-13 Solco Basel Ag Process for preparing cell and tissue regenerating substances

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NEANT *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2835292A1 (en) * 1977-08-16 1979-03-01 Cellorgan Sa Lab PROCESS FOR PRODUCING DEFIBRINIZED AND FREEZE-DRIED PLACENTA CELLS
DE3008900A1 (en) * 1979-03-09 1980-09-18 Nestle Sa METHOD FOR PRODUCING A PURIFIED PROTEIN HYDROLYSATE
FR2450842A1 (en) * 1979-03-09 1980-10-03 Nestle Sa PROCESS FOR THE PREPARATION OF A PURIFIED PROTEIN HYDROLYSATE
FR2484651A1 (en) * 1980-06-16 1981-12-18 Tena Lab Morrith Sa Gui Aminoacid and peptide soln. of animal origin e.g. milk - used to treat nerve cell disorders, obtd. by extn. of centrifugation to remove fatty constituents, adjustment of pH and removal of sediment
EP0095682A3 (en) * 1982-05-28 1984-06-13 Solco Basel Ag Process for preparing cell and tissue regenerating substances

Also Published As

Publication number Publication date
FR2195425B1 (en) 1977-02-25

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Legal Events

Date Code Title Description
ST Notification of lapse