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FR20C1038I1 - - Google Patents

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Publication number
FR20C1038I1
FR20C1038I1 FR20C1038C FR20C1038I1 FR 20C1038 I1 FR20C1038 I1 FR 20C1038I1 FR 20C1038 C FR20C1038 C FR 20C1038C FR 20C1038 I1 FR20C1038 I1 FR 20C1038I1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
Other languages
French (fr)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of FR20C1038I1 publication Critical patent/FR20C1038I1/fr
Application granted granted Critical
Publication of FR20C1038I2 publication Critical patent/FR20C1038I2/en
Active legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FR20C1038C 2007-06-29 2020-08-20 BENZAMIDAZOLE DERIVATIVES Active FR20C1038I2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US94728707P 2007-06-29 2007-06-29
US4164508P 2008-04-02 2008-04-02
PCT/IB2008/001575 WO2009004427A2 (en) 2007-06-29 2008-06-16 Benzimidazole derivatives

Publications (2)

Publication Number Publication Date
FR20C1038I1 true FR20C1038I1 (en) 2020-10-02
FR20C1038I2 FR20C1038I2 (en) 2021-08-13

Family

ID=40161351

Family Applications (1)

Application Number Title Priority Date Filing Date
FR20C1038C Active FR20C1038I2 (en) 2007-06-29 2020-08-20 BENZAMIDAZOLE DERIVATIVES

Country Status (46)

Country Link
US (2) US8148401B2 (en)
EP (1) EP2170860B9 (en)
JP (2) JP4567099B2 (en)
KR (1) KR101143246B1 (en)
CN (1) CN101687841B (en)
AP (1) AP2377A (en)
AR (1) AR067346A1 (en)
AU (1) AU2008272641B2 (en)
BR (1) BRPI0813412B8 (en)
CA (1) CA2690953C (en)
CL (1) CL2008001922A1 (en)
CO (1) CO6160232A2 (en)
CR (1) CR11150A (en)
CU (1) CU23847B1 (en)
CY (2) CY1118650T1 (en)
DK (1) DK2170860T5 (en)
DO (1) DOP2009000278A (en)
EA (1) EA016888B1 (en)
EC (1) ECSP099803A (en)
ES (1) ES2609258T3 (en)
FR (1) FR20C1038I2 (en)
GE (1) GEP20125702B (en)
GT (1) GT200900328A (en)
HK (1) HK1139658A1 (en)
HN (1) HN2008000974A (en)
HR (1) HRP20161562T2 (en)
HU (2) HUE030052T4 (en)
IL (1) IL202420A (en)
LT (2) LT2170860T (en)
MA (1) MA31466B1 (en)
ME (1) ME00962B (en)
MY (1) MY148636A (en)
NI (1) NI200900219A (en)
NL (1) NL301057I2 (en)
NO (1) NO2020027I1 (en)
NZ (1) NZ581889A (en)
PA (1) PA8785401A1 (en)
PE (2) PE20090772A1 (en)
PL (1) PL2170860T3 (en)
PT (1) PT2170860T (en)
RS (1) RS55395B9 (en)
SI (1) SI2170860T1 (en)
TN (1) TN2009000544A1 (en)
TW (1) TWI371451B (en)
UY (1) UY31164A1 (en)
WO (1) WO2009004427A2 (en)

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CA2690953C (en) 2007-06-29 2012-10-02 Pfizer Inc. Benzimidazole derivatives
CA2735593C (en) 2008-09-03 2017-08-15 Repligen Corporation Compositions including 6-aminohexanoic acid derivatives as hdac inhibitors
RU2533825C2 (en) * 2009-06-11 2014-11-20 Сиена Байотек С.П.А. BENZIMIDAZOLE AND IMIDAZO[4,5-c]PYRIDINE DERIVATIVES AS HEDGEHOG PATHWAY ANTAGONIST
MX2012002419A (en) 2009-08-26 2012-04-19 Takeda Pharmaceutical Fused heterocyclic ring derivative and use thereof.
US10420665B2 (en) 2010-06-13 2019-09-24 W. L. Gore & Associates, Inc. Intragastric device for treating obesity
US10010439B2 (en) 2010-06-13 2018-07-03 Synerz Medical, Inc. Intragastric device for treating obesity
US9526648B2 (en) 2010-06-13 2016-12-27 Synerz Medical, Inc. Intragastric device for treating obesity
US8628554B2 (en) 2010-06-13 2014-01-14 Virender K. Sharma Intragastric device for treating obesity
JP5802756B2 (en) 2010-10-20 2015-11-04 ファイザー・インク Pyridine-2-derivatives as smoothened receptor modulators
JP5452459B2 (en) 2010-12-16 2014-03-26 株式会社Nttドコモ Home base station and handover method
US10059723B2 (en) 2011-02-28 2018-08-28 Biomarin Pharmaceutical Inc. Histone deacetylase inhibitors
US9540395B2 (en) 2011-02-28 2017-01-10 Biomarin Pharmaceutical Inc. Histone deacetylase inhibitors
US8957066B2 (en) 2011-02-28 2015-02-17 Biomarin Pharmaceutical Inc. Histone deacetylase inhibitors
EP2684167B1 (en) 2011-03-08 2020-09-09 Eutropics Pharmaceuticals, Inc. Compositions and methods useful for treating diseases
FR2980477B1 (en) 2011-09-23 2013-10-18 Centre Nat Rech Scient NOVEL MODULATING COMPOUNDS OF THE HEDGEHOG PROTEIN SIGNALING PATH, THEIR MARKED FORMS, AND APPLICATIONS
CN103814024B (en) * 2011-09-26 2016-11-23 默克专利股份公司 Benzylpiperidine compound as lysophosphatidic acid (LPA) receptor antagonist
EP2863920B1 (en) 2012-06-20 2023-03-22 Eutropics Pharmaceuticals, Inc. Quinoline derivatives for use in the tratment of breast cancer
WO2014081953A1 (en) 2012-11-21 2014-05-30 Richard David J Methods and compositions useful for treating diseases involving bcl-2 family proteins with isoquinoline and quinoline derivatives
PT2970139T (en) 2013-03-15 2018-08-01 Biomarin Pharm Inc Hdac inhibitors
EP2996689A1 (en) 2013-04-17 2016-03-23 Albert-Ludwigs-Universität Freiburg Compounds for use as bromodomain inhibitors
US10732182B2 (en) 2013-08-01 2020-08-04 Eutropics Pharmaceuticals, Inc. Method for predicting cancer sensitivity
GB2519344A (en) * 2013-10-18 2015-04-22 Redx Pharma Ltd Compounds
US10640803B2 (en) 2013-10-30 2020-05-05 Eutropics Pharmaceuticals, Inc. Methods for determining chemosensitivity and chemotoxicity
BR112017021075B1 (en) 2015-04-24 2021-08-03 Pfizer Inc. CRYSTALLINE FORM OF MALEATE OF 1-((2R,4R)-2-(1H-BENZO[D]IMIDAZOL-2-YL)-1-METHYLPIPERIDIN-4-YL)-3-(4-CYANOPHENYL)UREA AND PHARMACEUTICAL COMPOSITION
US10779980B2 (en) 2016-04-27 2020-09-22 Synerz Medical, Inc. Intragastric device for treating obesity
JP2020164722A (en) * 2019-03-29 2020-10-08 デクセリアルズ株式会社 Adhesive composition
EP4097093B8 (en) 2020-01-28 2024-02-28 Assia Chemical Industries LTD Processes for the preparation of glasdegib and salt thereof and solid state forms of glasdegib maleate and process for preparation thereof
CN113248475B (en) * 2020-02-11 2023-03-17 中国科学院上海药物研究所 Heterocyclic substituted benzimidazole dimer or pharmaceutically acceptable salt, composition and application thereof
EP4126237B1 (en) 2020-03-26 2024-04-10 LEK Pharmaceuticals d.d. Dimaleate form of 1-((2r,4r)-2-(1h-benzo[d]imidazol-2-yl)-1-methylpiperidin-4-yl)-3-(4-cyanophenyl)urea
CA3184767A1 (en) 2020-06-26 2021-12-30 Raqualia Pharma Inc. Method for selecting cancer patients for whom combination therapy with retinoid and cancer therapeutic agent is effective, and combination medicament with retinoid and cancer therapeutic agent
WO2023002362A1 (en) 2021-07-22 2023-01-26 Pfizer Inc. Treatment of hematological malignancy

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EP1482928B1 (en) 2001-07-27 2009-09-23 Curis, Inc. Mediators of hedgehog signaling pathways,compositions and uses related thereto
HUP0402184A2 (en) * 2001-12-04 2005-02-28 Actelion Pharmaceuticals Ltd. 4-(piperidyl- and pyrrolidyl-alkyl-ureido)-quinolines as urotensin ii receptor antagonists and pharmaceutical compositions containing them
TW200304820A (en) 2002-03-25 2003-10-16 Avanir Pharmaceuticals Use of benzimidazole analogs in the treatment of cell proliferation
AU2003301436A1 (en) 2002-10-17 2004-05-04 Amgen Inc. Benzimidazole derivatives and their use as vanilloid receptor ligands
WO2005042495A1 (en) 2003-10-21 2005-05-12 Imclone Systems Incorporated (benzimidazol-2-yl)-phenyl-phenyl-urea compounds and methods for inhibiting heparanase activity
EP1678145A2 (en) 2003-10-28 2006-07-12 Vertex Pharmaceuticals Incorporated Benzimidazoles useful as modulators of ion channels
NZ555419A (en) * 2004-11-03 2009-07-31 Curis Inc Mediators of the hedgehog gene signaling pathways, compositions and uses related thereto
DE102005012875B4 (en) 2005-03-19 2006-11-16 Sanofi-Aventis Deutschland Gmbh Use of amino-substituted 8-N-benzimidazoles
WO2006124780A2 (en) * 2005-05-12 2006-11-23 Kalypsys, Inc. Ih-benzo [d] imidazole compounds as inhibitors of b-raf kinase
WO2008064830A1 (en) 2006-11-27 2008-06-05 Ucb Pharma, S.A. Bicyclic and heterobicyclic derivatives, processes for preparing them and their pharmaceutical uses
US20100029615A1 (en) 2006-12-15 2010-02-04 Michael John Munchhof Benzimidazole derivatives
CA2690953C (en) 2007-06-29 2012-10-02 Pfizer Inc. Benzimidazole derivatives
WO2009154739A2 (en) 2008-06-17 2009-12-23 Duke University Smoothened receptor modulators
JP5555236B2 (en) 2008-08-25 2014-07-23 アイアールエム・リミテッド・ライアビリティ・カンパニー Hedgehog pathway modulator

Also Published As

Publication number Publication date
EP2170860B9 (en) 2017-02-22
BRPI0813412B1 (en) 2020-01-21
AR067346A1 (en) 2009-10-07
PT2170860T (en) 2017-01-04
WO2009004427A2 (en) 2009-01-08
BRPI0813412A2 (en) 2014-12-30
WO2009004427A3 (en) 2009-06-04
KR101143246B1 (en) 2012-05-18
CY2020028I1 (en) 2020-11-25
DK2170860T3 (en) 2017-01-09
HN2008000974A (en) 2011-01-24
EA016888B1 (en) 2012-08-30
HUE030052T4 (en) 2017-06-28
US20090005416A1 (en) 2009-01-01
FR20C1038I2 (en) 2021-08-13
ES2609258T3 (en) 2017-04-19
CU20090225A7 (en) 2012-02-15
LTC2170860I2 (en) 2022-03-10
TW200911792A (en) 2009-03-16
CA2690953A1 (en) 2009-01-08
CY1118650T1 (en) 2017-07-12
EA200971104A1 (en) 2010-06-30
CL2008001922A1 (en) 2009-01-02
PL2170860T3 (en) 2017-05-31
NI200900219A (en) 2010-03-11
PE20090772A1 (en) 2009-06-24
CU23847B1 (en) 2012-10-15
HRP20161562T1 (en) 2016-12-30
UY31164A1 (en) 2009-01-30
CY2020028I2 (en) 2020-11-25
AP2377A (en) 2012-03-07
HK1139658A1 (en) 2010-09-24
LTPA2020528I1 (en) 2020-09-25
DK2170860T5 (en) 2017-03-20
CA2690953C (en) 2012-10-02
PA8785401A1 (en) 2009-01-23
HUS2000031I1 (en) 2020-09-28
KR20100028120A (en) 2010-03-11
SI2170860T1 (en) 2017-01-31
RS55395B1 (en) 2017-04-28
ECSP099803A (en) 2010-01-29
US8148401B2 (en) 2012-04-03
TWI371451B (en) 2012-09-01
GEP20125702B (en) 2012-12-10
NZ581889A (en) 2011-05-27
RS55395B9 (en) 2020-01-31
HUE030052T2 (en) 2017-04-28
JP2010531869A (en) 2010-09-30
ME00962B (en) 2012-06-20
BRPI0813412B8 (en) 2021-05-25
HRP20161562T2 (en) 2017-04-21
PE20121010A1 (en) 2012-08-06
LT2170860T (en) 2017-01-10
TN2009000544A1 (en) 2011-03-31
IL202420A (en) 2014-05-28
US8431597B2 (en) 2013-04-30
DOP2009000278A (en) 2009-12-31
EP2170860A2 (en) 2010-04-07
NL301057I1 (en) 2020-07-22
AU2008272641B2 (en) 2013-08-29
MA31466B1 (en) 2010-06-01
US20120157495A1 (en) 2012-06-21
JP2010280693A (en) 2010-12-16
AU2008272641A1 (en) 2009-01-08
CN101687841B (en) 2013-07-10
AP2009005089A0 (en) 2009-12-31
CN101687841A (en) 2010-03-31
MY148636A (en) 2013-05-15
NL301057I2 (en) 2020-09-10
IL202420A0 (en) 2010-06-30
CR11150A (en) 2010-02-08
EP2170860B1 (en) 2016-11-02
JP4567099B2 (en) 2010-10-20
CO6160232A2 (en) 2010-05-20
GT200900328A (en) 2011-08-29
NO2020027I1 (en) 2020-08-11

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