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FR2059979A1 - Subst n-benzyl tetrahydroisoquinolinesantiin - Google Patents

Subst n-benzyl tetrahydroisoquinolinesantiin

Info

Publication number
FR2059979A1
FR2059979A1 FR6928737A FR6928737A FR2059979A1 FR 2059979 A1 FR2059979 A1 FR 2059979A1 FR 6928737 A FR6928737 A FR 6928737A FR 6928737 A FR6928737 A FR 6928737A FR 2059979 A1 FR2059979 A1 FR 2059979A1
Authority
FR
France
Prior art keywords
benzyl
subst
tetrahydroisoquinolinesantiin
alkoxy
antiinflammatory
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR6928737A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Priority to FR6928737A priority Critical patent/FR2059979A1/en
Publication of FR2059979A1 publication Critical patent/FR2059979A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Subst. N-benzyl tetrahydroisoquinolines antiinflammatory agents Novel antiinflammatory isoquinoline derivs. of formula: (where X1 and X2 = same or different (1-3C) alkoxy or H but X1 = X2 is not equal H; Y = (1-4C) alkoxy, halogen, CF3, OH, mono or dialkylamino) and their acid addition salts are prepd. by reacting N-(3'-Y-benzyl)-2-(3-X1, 4-X2 phenyl)-ethylamine with CH2O in an acid medium.
FR6928737A 1969-08-21 1969-08-21 Subst n-benzyl tetrahydroisoquinolinesantiin Withdrawn FR2059979A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR6928737A FR2059979A1 (en) 1969-08-21 1969-08-21 Subst n-benzyl tetrahydroisoquinolinesantiin

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR6928737A FR2059979A1 (en) 1969-08-21 1969-08-21 Subst n-benzyl tetrahydroisoquinolinesantiin

Publications (1)

Publication Number Publication Date
FR2059979A1 true FR2059979A1 (en) 1971-06-11

Family

ID=9039269

Family Applications (1)

Application Number Title Priority Date Filing Date
FR6928737A Withdrawn FR2059979A1 (en) 1969-08-21 1969-08-21 Subst n-benzyl tetrahydroisoquinolinesantiin

Country Status (1)

Country Link
FR (1) FR2059979A1 (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4261998A (en) 1978-05-18 1981-04-14 Synthelabo Tetrahydro-isoquinoline derivatives
EP0051190A3 (en) * 1980-10-17 1982-06-23 Pennwalt Corporation N-(amino(or hydroxy) phenethyl)-1,2,3,4-tetrahydroisoquinolines, precursors thereof, and methods of preparation
WO1987005295A1 (en) * 1986-03-05 1987-09-11 Universite Louis Pasteur Derivatives of (nitro-2 or amino-2 benzyl)-2 tetrahydro-1,2,3,4 isoquinoleines, as well as methods for obtaining them and pharmaceutical compositions containing them
US4766131A (en) * 1980-10-17 1988-08-23 Pennwalt Corporation 2-amino (or hydroxy) phenethyl-1,2,3,4-tetrahydroisoquinolines as analgesics

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4261998A (en) 1978-05-18 1981-04-14 Synthelabo Tetrahydro-isoquinoline derivatives
EP0051190A3 (en) * 1980-10-17 1982-06-23 Pennwalt Corporation N-(amino(or hydroxy) phenethyl)-1,2,3,4-tetrahydroisoquinolines, precursors thereof, and methods of preparation
US4766131A (en) * 1980-10-17 1988-08-23 Pennwalt Corporation 2-amino (or hydroxy) phenethyl-1,2,3,4-tetrahydroisoquinolines as analgesics
WO1987005295A1 (en) * 1986-03-05 1987-09-11 Universite Louis Pasteur Derivatives of (nitro-2 or amino-2 benzyl)-2 tetrahydro-1,2,3,4 isoquinoleines, as well as methods for obtaining them and pharmaceutical compositions containing them
EP0236251A3 (en) * 1986-03-05 1988-03-02 Universite Louis Pasteur (Strasbourg I) 2-(2-aminobenzyl)-1,2,3,4-tetrahydroisoquinolines, processes for obtaining them and pharmaceutical compositions containing them
US4925943A (en) * 1986-03-05 1990-05-15 Isabelle Kanmacher 2-(2-aminobenzyl or 2-nitrobenzyl)-1,2,3,4-tetrahydroisoquinoline derivatives

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