FR19C1043I1 - - Google Patents
Info
- Publication number
- FR19C1043I1 FR19C1043I1 FR19C1043C FR19C1043I1 FR 19C1043 I1 FR19C1043 I1 FR 19C1043I1 FR 19C1043 C FR19C1043 C FR 19C1043C FR 19C1043 I1 FR19C1043 I1 FR 19C1043I1
- Authority
- FR
- France
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007198590 | 2007-07-31 | ||
PCT/JP2008/063541 WO2009017098A1 (en) | 2007-07-31 | 2008-07-29 | Pharmaceutical composition containing optically active compound having thrombopoietin receptor agonist activity and intermediate thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
FR19C1043I1 true FR19C1043I1 (en) | 2019-08-09 |
FR19C1043I2 FR19C1043I2 (en) | 2020-04-03 |
Family
ID=40304328
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR19C1043C Active FR19C1043I2 (en) | 2007-07-31 | 2019-06-28 | PHARMACEUTICAL COMPOSITION CONTAINING AN OPTICALLY ACTIVE COMPOUND HAVING THROMBOPOETIN RECEPTOR AGONIST ACTIVITY AND INTERMEDIATE |
Country Status (21)
Country | Link |
---|---|
US (2) | US8530668B2 (en) |
EP (1) | EP2184279B1 (en) |
JP (1) | JP5164181B2 (en) |
KR (1) | KR20100027243A (en) |
CN (4) | CN101809008B (en) |
AU (1) | AU2008283357B2 (en) |
BR (1) | BRPI0814891A2 (en) |
CA (1) | CA2694567C (en) |
CY (1) | CY1116190T1 (en) |
DK (1) | DK2184279T3 (en) |
ES (1) | ES2528196T3 (en) |
FR (1) | FR19C1043I2 (en) |
HR (1) | HRP20150062T1 (en) |
MX (1) | MX2010001082A (en) |
NL (1) | NL300998I2 (en) |
PL (1) | PL2184279T3 (en) |
PT (1) | PT2184279E (en) |
RU (1) | RU2476429C2 (en) |
SI (1) | SI2184279T1 (en) |
TW (1) | TWI422371B (en) |
WO (1) | WO2009017098A1 (en) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI564008B (en) | 2010-09-30 | 2017-01-01 | 鹽野義製藥股份有限公司 | Formulation for solubility enhancement of poorly soluble drugs |
TW201406373A (en) | 2012-06-29 | 2014-02-16 | Shionogi & Co | A pharmaceutical composition containing compound having thrombopoietin receptor agonistic activity |
US20140047572A1 (en) * | 2012-08-13 | 2014-02-13 | University Of Rochester | Thrombopoietin mimetics for the treatment of radiation or chemical induced bone marrow injury |
WO2015093586A1 (en) * | 2013-12-20 | 2015-06-25 | 塩野義製薬株式会社 | Methods respectively for producing optically active compound having agonistic activity on thrombopoietin receptors and intermediate of said compound |
CN105412930A (en) * | 2015-08-07 | 2016-03-23 | 军事医学科学院华南干细胞与再生医学研究中心 | Application of TPO (thrombopoietin) receptor agonist in promoting homing of HSCs (hematopoietic stem cells) |
JP6168579B1 (en) * | 2016-02-12 | 2017-07-26 | 塩野義製薬株式会社 | Platelet production promoter containing Rustrombopag for patients with severe liver dysfunction |
CN106083759B (en) * | 2016-06-15 | 2022-02-15 | 上海丸全化学科技有限公司 | Brand-new synthesis process of lutofopa |
WO2018045907A1 (en) | 2016-09-08 | 2018-03-15 | 四川科伦博泰生物医药股份有限公司 | Novel 2-acylaminothiazole derivative and preparation method therefor and use thereof |
CN106565625B (en) * | 2016-11-04 | 2018-01-30 | 杭州励德生物科技有限公司 | A kind of antiplatelet reduces the preparation method of disease new drug Lusutrombopag intermediates |
WO2018149309A1 (en) * | 2017-02-14 | 2018-08-23 | 四川科伦药物研究院有限公司 | Crystal form of 4-phenylthiazole derivative and preparation method thereof |
CN109970678B (en) * | 2017-12-28 | 2024-03-08 | 四川科伦药物研究院有限公司 | Amorphous 4-phenylthiazole derivative, and preparation method and application thereof |
WO2019233328A1 (en) * | 2018-06-08 | 2019-12-12 | 四川科伦药物研究院有限公司 | Crystal form of 4-phenylthiazole derivative and preparation method thereof |
CN113164455A (en) * | 2018-12-04 | 2021-07-23 | 盐野义制药株式会社 | Solid dispersion of poorly soluble drug |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR9608587A (en) | 1995-06-07 | 1999-01-05 | Glaxo Group Ltd | Compound that binds to the thrombopoietin receptor pharmaceutical composition and process for treating a patient suffering from a disorder |
JPH1072492A (en) | 1996-09-02 | 1998-03-17 | Hokuriku Seiyaku Co Ltd | Peptide compound |
JPH10287634A (en) | 1997-04-11 | 1998-10-27 | Otsuka Pharmaceut Co Ltd | Benzene derivatives |
JPH111477A (en) | 1997-06-12 | 1999-01-06 | Hokuriku Seiyaku Co Ltd | 1,4-benzodiazepine and use thereof |
JPH11152276A (en) | 1997-11-20 | 1999-06-08 | Hokuriku Seiyaku Co Ltd | Benzodiazepine derivative |
GB9823871D0 (en) * | 1998-10-30 | 1998-12-23 | Pharmacia & Upjohn Spa | 2-Amino-thiazole derivatives, process for their preparation, and their use as antitumour agents |
GC0000177A (en) | 1998-12-17 | 2006-03-29 | Smithkline Beecham | Thrombopoietin mimetics |
CA2380206A1 (en) | 1999-07-26 | 2001-02-01 | Shionogi & Co., Ltd. | Pharmaceutical compositions exhibiting thrombopoietin receptor agonism |
TWI284639B (en) * | 2000-01-24 | 2007-08-01 | Shionogi & Co | A compound having thrombopoietin receptor agonistic effect |
CA2435143A1 (en) | 2001-01-26 | 2002-08-01 | Shionogi & Co., Ltd. | Halogen compounds having thrombopoietin receptor agonism |
US7169931B2 (en) | 2001-01-26 | 2007-01-30 | Shionogi & Co., Ltd. | Cyclic compounds exhibiting thrombopoietin receptor agonism |
US20040077697A1 (en) | 2001-02-02 | 2004-04-22 | Hiroyuki Koshio | 2-Acylaminothiazole derivative or its salt |
JP4120586B2 (en) | 2002-01-18 | 2008-07-16 | アステラス製薬株式会社 | 2-acylaminothiazole derivatives or salts thereof |
AU2003268687A1 (en) | 2002-09-30 | 2004-04-19 | Yamanouchi Pharmaceutical Co., Ltd. | Novel salt of 2-acylaminothiazole derivative |
US6737382B1 (en) * | 2002-10-23 | 2004-05-18 | Nippon Soda Co. Ltd. | Insecticidal aminothiazole derivatives |
FR2854158B1 (en) * | 2003-04-25 | 2006-11-17 | Sanofi Synthelabo | 2-ACYLAMINO-4-PHENYLETHIAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE |
CA2529686C (en) | 2003-07-17 | 2010-06-15 | Astellas Pharma Inc. | 2-acylaminothiazole derivative or salt thereof |
AU2004263442B2 (en) * | 2003-08-12 | 2008-05-29 | Shionogi & Co., Ltd. | Compounds having thrombopoietin receptor agonism |
RU2006111093A (en) * | 2003-09-06 | 2007-10-27 | Вертекс Фармасьютикалз Инкорпорейтед (Us) | MODULATORS OF ATR-BINDING CASSETTE TRANSPORTERS |
JP4665769B2 (en) | 2005-01-12 | 2011-04-06 | アステラス製薬株式会社 | Method for producing acylaminothiazole derivative |
JP4774995B2 (en) | 2005-01-12 | 2011-09-21 | アステラス製薬株式会社 | Pharmaceutical composition comprising an acylaminothiazole derivative as an active ingredient |
WO2007004038A1 (en) | 2005-07-05 | 2007-01-11 | Pfizer Products Inc. | Aminothiazole derivatives as agonists of the thrombopoietin receptor |
US8515798B2 (en) | 2005-09-27 | 2013-08-20 | Accenture Global Services Gmbh | Closed-loop supply chain in the paper packaging sector |
WO2007054783A2 (en) | 2005-11-08 | 2007-05-18 | Astellas Pharma Inc. | Compositions and methods for treating thrombocytopenia |
-
2008
- 2008-07-29 AU AU2008283357A patent/AU2008283357B2/en active Active
- 2008-07-29 SI SI200831361T patent/SI2184279T1/en unknown
- 2008-07-29 ES ES08791776.1T patent/ES2528196T3/en active Active
- 2008-07-29 JP JP2009525398A patent/JP5164181B2/en active Active
- 2008-07-29 CN CN2008801104301A patent/CN101809008B/en active Active
- 2008-07-29 RU RU2010107169/04A patent/RU2476429C2/en active
- 2008-07-29 MX MX2010001082A patent/MX2010001082A/en active IP Right Grant
- 2008-07-29 US US12/671,476 patent/US8530668B2/en active Active
- 2008-07-29 EP EP08791776.1A patent/EP2184279B1/en active Active
- 2008-07-29 CA CA2694567A patent/CA2694567C/en active Active
- 2008-07-29 CN CN201310356507.6A patent/CN103450110B/en active Active
- 2008-07-29 BR BRPI0814891-0A patent/BRPI0814891A2/en not_active IP Right Cessation
- 2008-07-29 DK DK08791776.1T patent/DK2184279T3/en active
- 2008-07-29 PL PL08791776T patent/PL2184279T3/en unknown
- 2008-07-29 CN CN201310356204.4A patent/CN103396313B/en active Active
- 2008-07-29 KR KR1020107002144A patent/KR20100027243A/en active Search and Examination
- 2008-07-29 PT PT87917761T patent/PT2184279E/en unknown
- 2008-07-29 WO PCT/JP2008/063541 patent/WO2009017098A1/en active Application Filing
- 2008-07-29 CN CN2013103563691A patent/CN103393678A/en active Pending
- 2008-07-30 TW TW097128751A patent/TWI422371B/en active
-
2013
- 2013-02-13 US US13/766,752 patent/US8889722B2/en active Active
-
2015
- 2015-01-19 HR HRP20150062AT patent/HRP20150062T1/en unknown
- 2015-01-21 CY CY20151100059T patent/CY1116190T1/en unknown
-
2019
- 2019-06-27 NL NL300998C patent/NL300998I2/en unknown
- 2019-06-28 FR FR19C1043C patent/FR19C1043I2/en active Active
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