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FR19C1043I1 - - Google Patents

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Publication number
FR19C1043I1
FR19C1043I1 FR19C1043C FR19C1043I1 FR 19C1043 I1 FR19C1043 I1 FR 19C1043I1 FR 19C1043 C FR19C1043 C FR 19C1043C FR 19C1043 I1 FR19C1043 I1 FR 19C1043I1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
Other languages
French (fr)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of FR19C1043I1 publication Critical patent/FR19C1043I1/fr
Application granted granted Critical
Publication of FR19C1043I2 publication Critical patent/FR19C1043I2/en
Active legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38Nitrogen atoms
    • C07D277/44Acylated amino or imino radicals
    • C07D277/46Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR19C1043C 2007-07-31 2019-06-28 PHARMACEUTICAL COMPOSITION CONTAINING AN OPTICALLY ACTIVE COMPOUND HAVING THROMBOPOETIN RECEPTOR AGONIST ACTIVITY AND INTERMEDIATE Active FR19C1043I2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007198590 2007-07-31
PCT/JP2008/063541 WO2009017098A1 (en) 2007-07-31 2008-07-29 Pharmaceutical composition containing optically active compound having thrombopoietin receptor agonist activity and intermediate thereof

Publications (2)

Publication Number Publication Date
FR19C1043I1 true FR19C1043I1 (en) 2019-08-09
FR19C1043I2 FR19C1043I2 (en) 2020-04-03

Family

ID=40304328

Family Applications (1)

Application Number Title Priority Date Filing Date
FR19C1043C Active FR19C1043I2 (en) 2007-07-31 2019-06-28 PHARMACEUTICAL COMPOSITION CONTAINING AN OPTICALLY ACTIVE COMPOUND HAVING THROMBOPOETIN RECEPTOR AGONIST ACTIVITY AND INTERMEDIATE

Country Status (21)

Country Link
US (2) US8530668B2 (en)
EP (1) EP2184279B1 (en)
JP (1) JP5164181B2 (en)
KR (1) KR20100027243A (en)
CN (4) CN101809008B (en)
AU (1) AU2008283357B2 (en)
BR (1) BRPI0814891A2 (en)
CA (1) CA2694567C (en)
CY (1) CY1116190T1 (en)
DK (1) DK2184279T3 (en)
ES (1) ES2528196T3 (en)
FR (1) FR19C1043I2 (en)
HR (1) HRP20150062T1 (en)
MX (1) MX2010001082A (en)
NL (1) NL300998I2 (en)
PL (1) PL2184279T3 (en)
PT (1) PT2184279E (en)
RU (1) RU2476429C2 (en)
SI (1) SI2184279T1 (en)
TW (1) TWI422371B (en)
WO (1) WO2009017098A1 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI564008B (en) 2010-09-30 2017-01-01 鹽野義製藥股份有限公司 Formulation for solubility enhancement of poorly soluble drugs
TW201406373A (en) 2012-06-29 2014-02-16 Shionogi & Co A pharmaceutical composition containing compound having thrombopoietin receptor agonistic activity
US20140047572A1 (en) * 2012-08-13 2014-02-13 University Of Rochester Thrombopoietin mimetics for the treatment of radiation or chemical induced bone marrow injury
WO2015093586A1 (en) * 2013-12-20 2015-06-25 塩野義製薬株式会社 Methods respectively for producing optically active compound having agonistic activity on thrombopoietin receptors and intermediate of said compound
CN105412930A (en) * 2015-08-07 2016-03-23 军事医学科学院华南干细胞与再生医学研究中心 Application of TPO (thrombopoietin) receptor agonist in promoting homing of HSCs (hematopoietic stem cells)
JP6168579B1 (en) * 2016-02-12 2017-07-26 塩野義製薬株式会社 Platelet production promoter containing Rustrombopag for patients with severe liver dysfunction
CN106083759B (en) * 2016-06-15 2022-02-15 上海丸全化学科技有限公司 Brand-new synthesis process of lutofopa
WO2018045907A1 (en) 2016-09-08 2018-03-15 四川科伦博泰生物医药股份有限公司 Novel 2-acylaminothiazole derivative and preparation method therefor and use thereof
CN106565625B (en) * 2016-11-04 2018-01-30 杭州励德生物科技有限公司 A kind of antiplatelet reduces the preparation method of disease new drug Lusutrombopag intermediates
WO2018149309A1 (en) * 2017-02-14 2018-08-23 四川科伦药物研究院有限公司 Crystal form of 4-phenylthiazole derivative and preparation method thereof
CN109970678B (en) * 2017-12-28 2024-03-08 四川科伦药物研究院有限公司 Amorphous 4-phenylthiazole derivative, and preparation method and application thereof
WO2019233328A1 (en) * 2018-06-08 2019-12-12 四川科伦药物研究院有限公司 Crystal form of 4-phenylthiazole derivative and preparation method thereof
CN113164455A (en) * 2018-12-04 2021-07-23 盐野义制药株式会社 Solid dispersion of poorly soluble drug

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9608587A (en) 1995-06-07 1999-01-05 Glaxo Group Ltd Compound that binds to the thrombopoietin receptor pharmaceutical composition and process for treating a patient suffering from a disorder
JPH1072492A (en) 1996-09-02 1998-03-17 Hokuriku Seiyaku Co Ltd Peptide compound
JPH10287634A (en) 1997-04-11 1998-10-27 Otsuka Pharmaceut Co Ltd Benzene derivatives
JPH111477A (en) 1997-06-12 1999-01-06 Hokuriku Seiyaku Co Ltd 1,4-benzodiazepine and use thereof
JPH11152276A (en) 1997-11-20 1999-06-08 Hokuriku Seiyaku Co Ltd Benzodiazepine derivative
GB9823871D0 (en) * 1998-10-30 1998-12-23 Pharmacia & Upjohn Spa 2-Amino-thiazole derivatives, process for their preparation, and their use as antitumour agents
GC0000177A (en) 1998-12-17 2006-03-29 Smithkline Beecham Thrombopoietin mimetics
CA2380206A1 (en) 1999-07-26 2001-02-01 Shionogi & Co., Ltd. Pharmaceutical compositions exhibiting thrombopoietin receptor agonism
TWI284639B (en) * 2000-01-24 2007-08-01 Shionogi & Co A compound having thrombopoietin receptor agonistic effect
CA2435143A1 (en) 2001-01-26 2002-08-01 Shionogi & Co., Ltd. Halogen compounds having thrombopoietin receptor agonism
US7169931B2 (en) 2001-01-26 2007-01-30 Shionogi & Co., Ltd. Cyclic compounds exhibiting thrombopoietin receptor agonism
US20040077697A1 (en) 2001-02-02 2004-04-22 Hiroyuki Koshio 2-Acylaminothiazole derivative or its salt
JP4120586B2 (en) 2002-01-18 2008-07-16 アステラス製薬株式会社 2-acylaminothiazole derivatives or salts thereof
AU2003268687A1 (en) 2002-09-30 2004-04-19 Yamanouchi Pharmaceutical Co., Ltd. Novel salt of 2-acylaminothiazole derivative
US6737382B1 (en) * 2002-10-23 2004-05-18 Nippon Soda Co. Ltd. Insecticidal aminothiazole derivatives
FR2854158B1 (en) * 2003-04-25 2006-11-17 Sanofi Synthelabo 2-ACYLAMINO-4-PHENYLETHIAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE
CA2529686C (en) 2003-07-17 2010-06-15 Astellas Pharma Inc. 2-acylaminothiazole derivative or salt thereof
AU2004263442B2 (en) * 2003-08-12 2008-05-29 Shionogi & Co., Ltd. Compounds having thrombopoietin receptor agonism
RU2006111093A (en) * 2003-09-06 2007-10-27 Вертекс Фармасьютикалз Инкорпорейтед (Us) MODULATORS OF ATR-BINDING CASSETTE TRANSPORTERS
JP4665769B2 (en) 2005-01-12 2011-04-06 アステラス製薬株式会社 Method for producing acylaminothiazole derivative
JP4774995B2 (en) 2005-01-12 2011-09-21 アステラス製薬株式会社 Pharmaceutical composition comprising an acylaminothiazole derivative as an active ingredient
WO2007004038A1 (en) 2005-07-05 2007-01-11 Pfizer Products Inc. Aminothiazole derivatives as agonists of the thrombopoietin receptor
US8515798B2 (en) 2005-09-27 2013-08-20 Accenture Global Services Gmbh Closed-loop supply chain in the paper packaging sector
WO2007054783A2 (en) 2005-11-08 2007-05-18 Astellas Pharma Inc. Compositions and methods for treating thrombocytopenia

Also Published As

Publication number Publication date
KR20100027243A (en) 2010-03-10
CN103393678A (en) 2013-11-20
US8889722B2 (en) 2014-11-18
SI2184279T1 (en) 2015-04-30
CN103450110A (en) 2013-12-18
US20100267783A1 (en) 2010-10-21
MX2010001082A (en) 2010-03-01
PT2184279E (en) 2015-02-05
RU2010107169A (en) 2011-09-10
CN101809008A (en) 2010-08-18
CA2694567A1 (en) 2009-02-05
TW200914000A (en) 2009-04-01
JP5164181B2 (en) 2013-03-13
US20130217885A1 (en) 2013-08-22
DK2184279T3 (en) 2015-01-26
NL300998I1 (en) 2019-07-03
FR19C1043I2 (en) 2020-04-03
CA2694567C (en) 2013-04-23
EP2184279A4 (en) 2011-11-02
JPWO2009017098A1 (en) 2010-10-21
US8530668B2 (en) 2013-09-10
WO2009017098A1 (en) 2009-02-05
BRPI0814891A2 (en) 2015-08-18
TWI422371B (en) 2014-01-11
PL2184279T3 (en) 2015-04-30
HRP20150062T1 (en) 2015-04-10
CN101809008B (en) 2013-09-18
RU2476429C2 (en) 2013-02-27
CY1116190T1 (en) 2017-02-08
EP2184279A1 (en) 2010-05-12
EP2184279B1 (en) 2014-11-12
ES2528196T3 (en) 2015-02-05
NL300998I2 (en) 2019-08-28
CN103396313A (en) 2013-11-20
AU2008283357A1 (en) 2009-02-05
CN103450110B (en) 2015-12-09
CN103396313B (en) 2015-05-13
AU2008283357B2 (en) 2011-08-11

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