FI952049A - Antimicrobial 5-hydrazino-quinolone derivatives - Google Patents
Antimicrobial 5-hydrazino-quinolone derivatives Download PDFInfo
- Publication number
- FI952049A FI952049A FI952049A FI952049A FI952049A FI 952049 A FI952049 A FI 952049A FI 952049 A FI952049 A FI 952049A FI 952049 A FI952049 A FI 952049A FI 952049 A FI952049 A FI 952049A
- Authority
- FI
- Finland
- Prior art keywords
- hydrazino
- antimicrobial
- quinolone derivatives
- quinolone
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US96896092A | 1992-10-30 | 1992-10-30 | |
| PCT/US1993/010091 WO1994010163A1 (en) | 1992-10-30 | 1993-10-22 | Antimicrobial 5-hydrazino-quinolone derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI952049A true FI952049A (en) | 1995-04-28 |
| FI952049A0 FI952049A0 (en) | 1995-04-28 |
Family
ID=25514997
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI952049A FI952049A0 (en) | 1992-10-30 | 1995-04-28 | Antimicrobial 5-hydrazino-quinolone derivatives |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP0666853A1 (en) |
| JP (1) | JPH08502750A (en) |
| KR (1) | KR950704301A (en) |
| CN (1) | CN1064357C (en) |
| AU (1) | AU687018B2 (en) |
| BR (1) | BR9307347A (en) |
| CA (1) | CA2148003A1 (en) |
| CZ (1) | CZ282581B6 (en) |
| EG (1) | EG20543A (en) |
| FI (1) | FI952049A0 (en) |
| HU (1) | HUT72072A (en) |
| IL (1) | IL107323A (en) |
| MX (1) | MX9306814A (en) |
| NO (1) | NO951640L (en) |
| NZ (1) | NZ257470A (en) |
| PL (1) | PL178094B1 (en) |
| RU (1) | RU2126000C1 (en) |
| SG (1) | SG59979A1 (en) |
| SK (1) | SK54795A3 (en) |
| WO (1) | WO1994010163A1 (en) |
| ZA (1) | ZA938089B (en) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5646163A (en) * | 1992-10-30 | 1997-07-08 | The Procter & Gamble Company | Quinolone 5-(N-heterosubstituted amino) antimicrobials |
| CA2196539C (en) * | 1994-08-02 | 2001-05-15 | The Procter & Gamble Company | Process for making quinolonyl lactam antimicrobials and novel intermediate compounds |
| ES2143644T3 (en) * | 1994-08-02 | 2000-05-16 | Procter & Gamble | PROCEDURE TO PREPARE ANTIMICROBIAL COMPOUNDS. |
| PT882725E (en) * | 1996-02-09 | 2003-04-30 | Toyama Chemical Co Ltd | DERIVATIVES OF QUINOLONACARBOXYLIC ACID OR ITS SALTS |
| JP5279487B2 (en) * | 2005-05-18 | 2013-09-04 | エムペックス・ファーマシューティカルズ・インコーポレーテッド | Aerosolized fluoroquinolones and uses thereof |
| US8524735B2 (en) | 2005-05-18 | 2013-09-03 | Mpex Pharmaceuticals, Inc. | Aerosolized fluoroquinolones and uses thereof |
| CA2528849C (en) | 2005-06-08 | 2014-01-14 | Janssen Pharmaceutica N.V. | Quinoline derivatives as antibacterial agents |
| EA010601B1 (en) * | 2005-06-09 | 2008-10-30 | Янссен Фармацевтика Н.В. | Quinoline derivatives as antibacterial agents |
| CN101020647B (en) * | 2007-02-14 | 2011-03-30 | 杭州师范学院 | Synthesis process of beta-cyclopropylamino acrylate |
| EP2150544B1 (en) | 2007-03-19 | 2016-01-13 | Takeda Pharmaceutical Company Limited | Mapk/erk kinase inhibitors |
| KR101601332B1 (en) * | 2007-10-05 | 2016-03-08 | 센화 바이오사이언시즈 인코포레이티드 | Quinolone analogs and methods related thereto |
| CN102046603B (en) * | 2008-06-03 | 2014-08-13 | 埃科特莱茵药品有限公司 | [4-(1-amino-ethyl)-cyclohexyl]-methyl-amine and [6-(1-amino-ethyl) -tetrahydro-pyran-3-yl]-methyl-amine derivatives as antibacterials |
| HUE050147T2 (en) | 2008-10-07 | 2020-11-30 | Horizon Orphan Llc | Inhalation of levofloxacin for reducing lung inflammation |
| LT2344129T (en) | 2008-10-07 | 2018-05-10 | Horizon Orphan Llc | Aerosol fluoroquinolone formulations for improved pharmacokinetics |
| AR076222A1 (en) * | 2009-04-09 | 2011-05-26 | Actelion Pharmaceuticals Ltd | DERIVATIVES 2-HYDROXIETIL-1H-QUINOLIN-ONA AND ITS AZAISOTHERAL ANALOGS WITH ANTIBACTERIAL ACTIVITY AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
| BR112012004692B8 (en) | 2009-09-04 | 2021-05-25 | Mpex Pharmaceuticals Inc | solution comprising levofloxacin for use in a method of treating cystic fibrosis in a human. |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4668680A (en) * | 1985-12-12 | 1987-05-26 | Warner-Lambert Company | 5-amino-6,8-difluoroquinolones as antibacterial agents |
| JPH0228178A (en) * | 1988-04-23 | 1990-01-30 | Toyama Chem Co Ltd | Novel pyridonecarboxylic acid derivative and salt thereof |
| DE3906365A1 (en) * | 1988-07-15 | 1990-01-18 | Bayer Ag | 7- (1-PYRROLIDINYL) -3-CHINOLONE AND NAPHTHYRIDONE CARBOXYLIC ACID DERIVATIVES, METHOD AND SUBSTITUTED (OXA) DIAZABICYCLOOCTANES AND NONANESE AS INTERMEDIATE PRODUCTS, AND ANTIBACTERIAL AGENTS AND FOOD ADDITIVES CONTAINING THEM |
| WO1991002526A1 (en) * | 1989-08-16 | 1991-03-07 | Pfizer Inc. | Azabicyclo quinolone carboxylic acids |
| WO1991016327A1 (en) * | 1990-04-18 | 1991-10-31 | Norwich Eaton Pharmaceuticals, Inc. | Antimicrobial quinolonyl lactams |
| EP0559774B1 (en) * | 1990-11-30 | 1999-07-07 | Warner-Lambert Company | Individual stereoisomers of 7- 3-(1-aminoalkyl)-1-pyrrolidinyl]-quinolones and naphthyridones as antibacterial agents |
-
1993
- 1993-01-30 EG EG68693A patent/EG20543A/en active
- 1993-10-19 IL IL10732393A patent/IL107323A/en not_active IP Right Cessation
- 1993-10-22 WO PCT/US1993/010091 patent/WO1994010163A1/en not_active Application Discontinuation
- 1993-10-22 RU RU95110762A patent/RU2126000C1/en active
- 1993-10-22 JP JP6511167A patent/JPH08502750A/en active Pending
- 1993-10-22 NZ NZ257470A patent/NZ257470A/en unknown
- 1993-10-22 BR BR9307347A patent/BR9307347A/en not_active Application Discontinuation
- 1993-10-22 KR KR1019950701690A patent/KR950704301A/en active IP Right Grant
- 1993-10-22 PL PL93308671A patent/PL178094B1/en unknown
- 1993-10-22 EP EP93924393A patent/EP0666853A1/en not_active Withdrawn
- 1993-10-22 CZ CZ951097A patent/CZ282581B6/en not_active IP Right Cessation
- 1993-10-22 CA CA002148003A patent/CA2148003A1/en not_active Abandoned
- 1993-10-22 AU AU54097/94A patent/AU687018B2/en not_active Ceased
- 1993-10-22 HU HU9501237A patent/HUT72072A/en unknown
- 1993-10-22 SK SK547-95A patent/SK54795A3/en unknown
- 1993-10-22 SG SG1996007851A patent/SG59979A1/en unknown
- 1993-10-29 MX MX9306814A patent/MX9306814A/en not_active IP Right Cessation
- 1993-10-29 ZA ZA938089A patent/ZA938089B/en unknown
- 1993-10-30 CN CN93120224A patent/CN1064357C/en not_active Expired - Fee Related
-
1995
- 1995-04-28 NO NO951640A patent/NO951640L/en unknown
- 1995-04-28 FI FI952049A patent/FI952049A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU687018B2 (en) | 1998-02-19 |
| SG59979A1 (en) | 1999-02-22 |
| MX9306814A (en) | 1994-07-29 |
| BR9307347A (en) | 1999-05-25 |
| CN1092773A (en) | 1994-09-28 |
| IL107323A0 (en) | 1994-01-25 |
| PL308671A1 (en) | 1995-08-21 |
| ZA938089B (en) | 1994-06-07 |
| NO951640L (en) | 1995-06-30 |
| NZ257470A (en) | 1997-08-22 |
| CZ282581B6 (en) | 1997-08-13 |
| AU5409794A (en) | 1994-05-24 |
| WO1994010163A1 (en) | 1994-05-11 |
| FI952049A0 (en) | 1995-04-28 |
| SK54795A3 (en) | 1995-12-06 |
| JPH08502750A (en) | 1996-03-26 |
| KR950704301A (en) | 1995-11-17 |
| RU95110762A (en) | 1997-01-10 |
| NO951640D0 (en) | 1995-04-28 |
| HU9501237D0 (en) | 1995-06-28 |
| CZ109795A3 (en) | 1995-12-13 |
| CN1064357C (en) | 2001-04-11 |
| CA2148003A1 (en) | 1994-05-11 |
| HUT72072A (en) | 1996-03-28 |
| EP0666853A1 (en) | 1995-08-16 |
| RU2126000C1 (en) | 1999-02-10 |
| IL107323A (en) | 2000-06-01 |
| EG20543A (en) | 1999-07-31 |
| PL178094B1 (en) | 2000-02-29 |
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