FI844777A0 - 2,2'-iminobisetanolderivat. - Google Patents

2,2'-iminobisetanolderivat.

Info

Publication number: FI844777A0
Authority: FI; Finland
Prior art keywords: iminobisetanolderivat
Prior art date: 1983-12-05

Application number

FI844777A

Other languages

English (en)

Other versions

FI82460C (fi

FI844777L (fi

FI82460B (fi

Inventor

Lommen Guy Rosalia Eugene Van

Bruyn Marcel Frans Leopold De

Marc Francis Josephin Schroven

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-12-05

Filing date

1984-12-04

Publication date

1984-12-04

1984-12-04 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

1984-12-04 Publication of FI844777A0 publication Critical patent/FI844777A0/fi

1985-06-06 Publication of FI844777L publication Critical patent/FI844777L/fi

1990-11-30 Application granted granted Critical

1990-11-30 Publication of FI82460B publication Critical patent/FI82460B/fi

1991-03-11 Publication of FI82460C publication Critical patent/FI82460C/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/66—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/92—Naphthopyrans; Hydrogenated naphthopyrans

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Furan Compounds (AREA)
Pyrane Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

FI844777A 1983-12-05 1984-12-04 Foerfarande foer framstaellning av nya, -adrenergiskt blockerande 2,2'-iminobisetanolderivat. FI82460C (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US55808183A	1983-12-05	1983-12-05
US55808183		1983-12-05

Publications (4)

Publication Number	Publication Date
FI844777A0 true FI844777A0 (fi)	1984-12-04
FI844777L FI844777L (fi)	1985-06-06
FI82460B FI82460B (fi)	1990-11-30
FI82460C FI82460C (fi)	1991-03-11

Family

ID=24228139

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI844777A FI82460C (fi)	1983-12-05	1984-12-04	Foerfarande foer framstaellning av nya, -adrenergiskt blockerande 2,2'-iminobisetanolderivat.

Country Status (32)

Country	Link
EP (1)	EP0145067B1 (fi)
JP (1)	JPS60132977A (fi)
KR (1)	KR870000923B1 (fi)
AR (1)	AR241414A1 (fi)
AT (1)	ATE40361T1 (fi)
AU (1)	AU573658B2 (fi)
BG (1)	BG43866A3 (fi)
CA (1)	CA1337429C (fi)
CS (1)	CS250242B2 (fi)
CY (1)	CY1609A (fi)
DD (1)	DD235453A5 (fi)
DE (1)	DE3476388D1 (fi)
DK (2)	DK165112C (fi)
DZ (1)	DZ712A1 (fi)
ES (1)	ES538256A0 (fi)
FI (1)	FI82460C (fi)
GR (1)	GR81098B (fi)
HK (1)	HK52791A (fi)
HU (1)	HU202219B (fi)
IE (1)	IE57831B1 (fi)
IL (1)	IL73706A (fi)
MA (1)	MA20292A1 (fi)
NO (2)	NO169839C (fi)
NZ (1)	NZ210388A (fi)
PH (1)	PH22432A (fi)
PL (1)	PL146342B1 (fi)
PT (1)	PT79609B (fi)
RO (1)	RO91184B (fi)
SG (1)	SG47091G (fi)
SU (1)	SU1428199A3 (fi)
ZA (1)	ZA849445B (fi)
ZW (1)	ZW19784A1 (fi)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1337432C (en) *	1988-03-23	1995-10-24	Raymond M. Xhonneux	Method of lowering the blood pressure
JPH02103116U (fi) *	1989-02-01	1990-08-16
JPH02218675A (ja) *	1989-02-21	1990-08-31	Nippon Kayaku Co Ltd	６―フルオロクロモン―２―カルボン酸及びその製造法
TW199152B (fi) *	1990-11-01	1993-02-01	Takeda Pharm Industry Co Ltd
TW355683B (en) *	1994-02-17	1999-04-11	Janssen Pharmaceutica Nv	Composition containing micronized nebivolol
DE69524528T2 (de) *	1994-10-14	2002-08-01	Merck Patent Gmbh	ZNS wirksames (R)-(-)-2-[5-(4-Fluorophenyl)-3-pyridylmethylaminomethyl]chroman
DK1040106T3 (da) *	1997-12-19	2002-12-02	Bayer Ag	Carboxylsubstituerede chromanderivater til anvendelse som beta 3 adrenoreceptor-agonister
US6362371B1 (en)	1998-06-08	2002-03-26	Advanced Medicine, Inc.	β2- adrenergic receptor agonists
US6713651B1 (en)	1999-06-07	2004-03-30	Theravance, Inc.	β2-adrenergic receptor agonists
US6593497B1 (en)	1999-06-02	2003-07-15	Theravance, Inc.	β2-adrenergic receptor agonists
US6683115B2 (en)	1999-06-02	2004-01-27	Theravance, Inc.	β2-adrenergic receptor agonists
UA73965C2 (en)	1999-12-08	2005-10-17	Theravance Inc	b2 ADRENERGIC RECEPTOR ANTAGONISTS
UA73981C2 (en)	2000-03-10	2005-10-17	Merck Patent Gmbh	(r)-(-)-2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]-chromane for treatment of extrapyramidal movement disorders (variants), pharmaceutical composition and kit
AU2002338528B2 (en)	2001-05-02	2008-01-24	Nicox S.A.	Nitrosated and nitrosylated nebivolol and its metabolites, compositions and methods of use
PL208258B1 (pl)	2001-07-26	2011-04-29	Merck Patent Gmbh	Nowe zastosowanie 2-[5-(4-fluorofenylo) -3- pirydylometyloaminometylo] -chromanu oraz jego fizjologicznie tolerowanych soli
WO2003042160A1 (en)	2001-11-13	2003-05-22	Theravance, Inc.	Aryl aniline beta-2 adrenergic receptor agonists
TWI249515B (en)	2001-11-13	2006-02-21	Theravance Inc	Aryl aniline beta2 adrenergic receptor agonists
WO2006025070A2 (en) *	2004-07-30	2006-03-09	Torrent Pharmaceuticals Limited	Nebivolol and its pharmaceutically acceptable salts, process for preparation and pharmaceutical compositions of nebivolol
EP1776354B1 (en) *	2004-08-11	2010-04-21	Hetero Drugs Limited	A novel process for preparation of nebivolol intermediates
CN100341866C (zh) *	2004-08-30	2007-10-10	中国科学院理化技术研究所	α，α’－[亚氨基二（亚甲基）]－双－（6－氟－3，4－二氢－2H－1－苯并吡喃－2－甲醇）甲烷磺酸盐的合成方法
CA2596426A1 (en) *	2005-01-31	2006-08-10	Mylan Laboratories, Inc.	Pharmaceutical composition comprising hydroxylated nebivolol
EP1850842A1 (de) *	2005-02-11	2007-11-07	Stada Arzneimittel Ag	Pharmazeutische zusammensetzungen nebivolo und ein hydrophiles polymer
AT502220A1 (de) *	2005-07-19	2007-02-15	Pharmacon Forschung & Beratung	Verfahren zur herstellung von nebivolol
US7560575B2 (en) *	2005-12-28	2009-07-14	Acino Pharma Ag	Process for preparation of racemic Nebivolol
EP1803716B1 (en) *	2005-12-28	2012-07-25	Acino Pharma AG	A process for preparation of racemic nebivolol
US7858812B2 (en)	2006-01-18	2010-12-28	Hetero Drugs Limited	Process for isolation of desired isomers of nebivolol intermediates
ITMI20061889A1 (it) *	2006-10-03	2008-04-04	Zambon Spa	Processo di preparazione di nebivololo
JP5259612B2 (ja)	2006-11-27	2013-08-07	ザックシステムエス．ピー．エー．	ネビボロールの調製法
EP2124931A4 (en)	2007-01-22	2013-08-28	Mylan Pharmaceuticals Ulc	PHARMACEUTICAL COMPOSITIONS COMPRISING NEBIVOLOL OR AN ANALOGUE OF NEBIVOLOL
CN101463024B (zh)	2007-12-21	2011-06-08	上海现代制药股份有限公司	一种制备rrrs和sssr型的奈必洛尔中间体混合物的方法
ITMI20080547A1 (it) *	2008-03-31	2009-10-01	Zach System Spa	Processo di preparazione di nebivololo
IT1392067B1 (it) *	2008-10-31	2012-02-09	Zach System Spa	Processo di preparazione di nebivololo
IT1395354B1 (it)	2009-07-23	2012-09-14	Zach System Spa	Processo di preparazione di nebivololo
DE102010005953A1 (de)	2010-01-27	2011-07-28	Corden PharmaChem GmbH, 68305	Verfahren zur Herstellung von Nebivolol
IT1397962B1 (it)	2010-02-11	2013-02-04	Menarini Int Operations Lu Sa	Processo per la preparazione del nebivololo.
IT1402974B1 (it)	2010-11-30	2013-09-27	Menarini Int Operations Lu Sa	Processo per la preparazione del nebivololo.
ITRM20110418A1 (it)	2011-08-02	2013-02-03	Menarini Int Operations Lu Sa	Processo per la preparazione di epossidi quali intermedi per la sintesi del nebivololo.
PT2907809T (pt)	2014-02-14	2019-01-16	Corden Pharma Int Gmbh	Processo sem base para a preparação de intermediários de cetona utilizáveis para fabrico de nebivolol
EP2907810A1 (en)	2014-02-14	2015-08-19	Corden Pharma International GmbH	A new method for producing nebivolol hydrochloride of high purity
DE102014107132A1 (de)	2014-05-20	2015-11-26	Corden Pharma International Gmbh	Verfahren zur Herstellung von Epoxiden die in der Herstellung von Nebivolol und dessen Derivaten einsetzbar sind
JP6847095B2 (ja)	2015-05-19	2021-03-24	チョーチアンオウスンファーマシューティカルカンパニーリミテッド	ネビボロールの合成方法及びその中間化合物
CN105085499B (zh) *	2015-08-07	2018-09-25	上海现代制药海门有限公司	盐酸奈必洛尔中间体混合物的结晶分离方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1054655A (fi) *	1964-01-24
US4313955A (en) *	1980-10-14	1982-02-02	Ciba-Geigy Corporation	1,5-Bis(1,4-benzodioxin-2-yl)-3-azapentane-1,5-diols
GB8418472D0 (en) *	1984-07-19	1984-08-22	Beecham Group Plc	Compounds

1984
- 1984-11-19 CA CA000468108A patent/CA1337429C/en not_active Expired - Fee Related
- 1984-11-21 PL PL1984250524A patent/PL146342B1/pl unknown
- 1984-11-22 AT AT84201693T patent/ATE40361T1/de not_active IP Right Cessation
- 1984-11-22 DE DE8484201693T patent/DE3476388D1/de not_active Expired
- 1984-11-22 EP EP84201693A patent/EP0145067B1/en not_active Expired
- 1984-11-26 KR KR1019840007404A patent/KR870000923B1/ko not_active IP Right Cessation
- 1984-11-29 NZ NZ210388A patent/NZ210388A/en unknown
- 1984-11-29 GR GR81098A patent/GR81098B/el unknown
- 1984-11-30 JP JP59252038A patent/JPS60132977A/ja active Granted
- 1984-12-02 DZ DZ847346A patent/DZ712A1/fr active
- 1984-12-03 IL IL73706A patent/IL73706A/xx not_active IP Right Cessation
- 1984-12-03 DD DD84270216A patent/DD235453A5/de not_active IP Right Cessation
- 1984-12-03 AR AR84298819A patent/AR241414A1/es active
- 1984-12-03 RO RO116496A patent/RO91184B/ro unknown
- 1984-12-04 HU HU844482A patent/HU202219B/hu unknown
- 1984-12-04 IE IE3103/84A patent/IE57831B1/en not_active IP Right Cessation
- 1984-12-04 BG BG067765A patent/BG43866A3/xx unknown
- 1984-12-04 NO NO844845A patent/NO169839C/no not_active IP Right Cessation
- 1984-12-04 PT PT79609A patent/PT79609B/pt unknown
- 1984-12-04 MA MA20516A patent/MA20292A1/fr unknown
- 1984-12-04 ZA ZA849445A patent/ZA849445B/xx unknown
- 1984-12-04 SU SU843826501A patent/SU1428199A3/ru active
- 1984-12-04 ZW ZW197/84A patent/ZW19784A1/xx unknown
- 1984-12-04 DK DK577084A patent/DK165112C/da not_active IP Right Cessation
- 1984-12-04 ES ES538256A patent/ES538256A0/es active Granted
- 1984-12-04 PH PH31525A patent/PH22432A/en unknown
- 1984-12-04 FI FI844777A patent/FI82460C/fi active IP Right Grant
- 1984-12-04 CS CS849320A patent/CS250242B2/cs unknown
- 1984-12-05 AU AU36326/84A patent/AU573658B2/en not_active Expired
1991
- 1991-06-18 SG SG47091A patent/SG47091G/en unknown
- 1991-07-11 HK HK527/91A patent/HK52791A/xx not_active IP Right Cessation
1992
- 1992-01-31 DK DK011892A patent/DK165321C/da not_active IP Right Cessation
- 1992-04-03 CY CY1609A patent/CY1609A/xx unknown
2004
- 2004-11-26 NO NO2004007C patent/NO2004007I2/no unknown

Also Published As

Publication number	Publication date
PH22432A (en)	1988-09-12
EP0145067A3 (en)	1986-03-26
AR241414A1 (es)	1992-07-31
IL73706A0 (en)	1985-03-31
PL250524A1 (en)	1986-02-25
NO169839B (no)	1992-05-04
JPH0250114B2 (fi)	1990-11-01
DK165321C (da)	1993-03-29
SG47091G (en)	1991-07-26
DK165321B (da)	1992-11-09
BG43866A3 (en)	1988-08-15
HU202219B (en)	1991-02-28
DK165112B (da)	1992-10-12
EP0145067A2 (en)	1985-06-19
MA20292A1 (fr)	1985-07-01
GR81098B (en)	1984-12-17
IE843103L (en)	1985-06-05
NO844845L (no)	1985-06-06
DK165112C (da)	1993-03-01
ZW19784A1 (en)	1986-07-02
EP0145067B1 (en)	1989-01-25
DK577084A (da)	1985-06-06
DZ712A1 (fr)	2004-09-13
RO91184A (ro)	1987-07-30
KR870000923B1 (ko)	1987-05-07
KR850004485A (ko)	1985-07-15
ATE40361T1 (de)	1989-02-15
AU3632684A (en)	1985-06-13
FI82460C (fi)	1991-03-11
PT79609B (en)	1986-12-12
FI844777L (fi)	1985-06-06
NZ210388A (en)	1987-07-31
DK11892D0 (da)	1992-01-31
CA1337429C (en)	1995-10-24
NO2004007I1 (no)	2004-12-20
FI82460B (fi)	1990-11-30
IL73706A (en)	1988-07-31
HUT37418A (en)	1985-12-28
ES8603870A1 (es)	1986-01-01
DK11892A (da)	1992-01-31
HK52791A (en)	1991-07-19
ES538256A0 (es)	1986-01-01
AU573658B2 (en)	1988-06-16
CS250242B2 (en)	1987-04-16
DK577084D0 (da)	1984-12-04
ZA849445B (en)	1986-07-30
RO91184B (ro)	1987-07-31
IE57831B1 (en)	1993-04-21
DE3476388D1 (en)	1989-03-02
CY1609A (en)	1992-04-03
NO2004007I2 (no)	2005-05-09
DD235453A5 (de)	1986-05-07
PT79609A (en)	1985-01-01
PL146342B1 (en)	1989-01-31
SU1428199A3 (ru)	1988-09-30
NO169839C (no)	1992-08-12
JPS60132977A (ja)	1985-07-16

Publication	Publication Date	Title
FI844777A0 (fi)	1984-12-04	2,2'-iminobisetanolderivat.
FI842597A (fi)	1984-12-30	1,2,4-triazol-3-on- depressionslaekemdel.
FI853193L (fi)	1986-02-24	Smaertstillande 1,2-benzisotiazol-3 -ylpiperazinderivat.
FI842400A0 (fi)	1984-06-13	Naproxen- ochnaproxen-natriumtablet- naproxen-natriumtabletter, vilka frigoers kontrollerat.
ATE28329T1 (de)	1987-08-15	1,3-dioxan-5-ylalkensaeuren.
FI843169A (fi)	1985-02-12	Substituerade 2,6-substituerade pyridinfoereningar.
FI843779L (fi)	1985-03-31	Depressionslaekemedel, 1,2,4-triazolonfoereningar.
FI840821A (fi)	1984-09-04	Mjuk, fuktresistant pappersprodukt.
FI842803A (fi)	1985-01-14	Vridningselastisk, vibrationsdaempande axelkoppling.
FI834836A (fi)	1984-08-23	Sportsko, saerskilt skidsko.
MX21592A (es)	1994-01-31	1,3-oxazolidin-2-ona.
FI834712A (fi)	1984-07-12	Vridfoerslutning foer smaelta raomaterial, speciellt metallsmaeltor.
FI844051L (fi)	1985-04-19	Foerfarande foer dehalogenering av 6, 6-dibrompenicillansyra-1,1-dioxid.
FI840600A (fi)	1984-10-02	Aktiveringsledning foer supraledande anordningar, speciellt magneter.
FI834645A (fi)	1984-07-08	Vridstoet-, vrid- eller stoetmaskin.
FI843110A0 (fi)	1984-08-08	4'-halogenantracyklinglykosid.
FI842085A (fi)	1984-11-28	7-oxo-4-tia-1-azabicyklo/3,2,0/hept-2- en-derivat.
FI853421A0 (fi)	1985-09-06	7-oxo-4-tia-1-azabicyklo/3,2,0/ hept-2-enderivat.
FI841819A (fi)	1984-11-10	4,4'- alkylendipiperidinderivat.
IT8223097A0 (it)	1982-09-02	5-fenossifenil-tetraidro-1,3,5-tiadiazin-4-oni.
FI843527L (fi)	1985-03-10	Foerfarande foer framstaellning av dihydroaryloxialkylamino -1,2,4-triazolderivat.
NO821499L (no)	1982-11-08	2,4-dioxacykloheksanonderivat.
FI841307A (fi)	1984-10-06	Haolstamp, speciellt foer pappers- eller kartongvaror.
FI842268A (fi)	1984-12-15	Foerfarande foer framstaellning av 3,4-di -isobutyryloxi-n-metyl-fenetylamin.
FI844050L (fi)	1985-04-19	Foerfarande foer framstaellning av 6,6-dibrompenicillansyra-1,1-dioxid.

Legal Events

Date	Code	Title	Description
1997-07-23	ND	Supplementary protection certificate (spc) granted
1997-07-23	SPCG	Supplementary protection certificate granted	Spc suppl protection certif: L79 Extension date: 20091204
2004-08-31	FG	Patent granted	Owner name: JANSSEN PHARMACEUTICA N.V.

Date

Code

Title

Description

1997-07-23

Supplementary protection certificate (spc) granted

1997-07-23

SPCG

Supplementary protection certificate granted

Spc suppl protection certif: L79

Extension date: 20091204

2004-08-31

Patent granted

Owner name: JANSSEN PHARMACEUTICA N.V.