FI67540C - Nya dikarboxylsyra-bis-(3,5-dikarbamoyl-2,4,6-trijodanilid)-derivat foer anvaendning som roentgenkontrastmedel och foerfarande foer framstaellning av dessa - Google Patents

Nya dikarboxylsyra-bis-(3,5-dikarbamoyl-2,4,6-trijodanilid)-derivat foer anvaendning som roentgenkontrastmedel och foerfarande foer framstaellning av dessa Download PDF

Info

Publication number: FI67540C
Authority: FI; Finland
Prior art keywords: bis; triiodanilide; acid; acid bis; dicarbamoyl
Prior art date: 1976-06-23

Application number

FI771900A

Other languages

English (en)

Finnish (fi)

Swedish (sv)

Other versions

FI771900A (no

FI67540B (fi

Inventor

Heinrich Pfeiffer

Ulrich Speck

Original Assignee

Schering Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-06-23

Filing date

1977-06-16

Publication date

1985-04-10

1977-06-16 Application filed by Schering Ag filed Critical Schering Ag

1977-12-24 Publication of FI771900A publication Critical patent/FI771900A/fi

1984-12-31 Application granted granted Critical

1984-12-31 Publication of FI67540B publication Critical patent/FI67540B/fi

1985-04-10 Publication of FI67540C publication Critical patent/FI67540C/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)
Polyesters Or Polycarbonates (AREA)
Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)

FI771900A 1976-06-23 1977-06-16 Nya dikarboxylsyra-bis-(3,5-dikarbamoyl-2,4,6-trijodanilid)-derivat foer anvaendning som roentgenkontrastmedel och foerfarande foer framstaellning av dessa FI67540C (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE2628517		1976-06-23
DE2628517A DE2628517C2 (de)	1976-06-23	1976-06-23	Dicarbonsäure-bis(3,5-dicarbamoyl-2,4,6-trijodanilid)-Verbindungen, Verfahren zu ihrer Herstellung und Röntgenkontrastmittel

Publications (3)

Publication Number	Publication Date
FI771900A FI771900A (no)	1977-12-24
FI67540B FI67540B (fi)	1984-12-31
FI67540C true FI67540C (fi)	1985-04-10

Family

ID=5981407

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI771900A FI67540C (fi)	1976-06-23	1977-06-16	Nya dikarboxylsyra-bis-(3,5-dikarbamoyl-2,4,6-trijodanilid)-derivat foer anvaendning som roentgenkontrastmedel och foerfarande foer framstaellning av dessa

Country Status (28)

Country	Link
US (1)	US4239747A (no)
JP (2)	JPS537637A (no)
AT (1)	AT361117B (no)
AU (1)	AU512304B2 (no)
BE (1)	BE856039A (no)
CA (2)	CA1106400A (no)
CH (1)	CH629751A5 (no)
CS (1)	CS199680B2 (no)
DD (1)	DD131014A5 (no)
DE (1)	DE2628517C2 (no)
DK (2)	DK150505C (no)
ES (1)	ES460007A1 (no)
FI (1)	FI67540C (no)
FR (1)	FR2355808A1 (no)
GB (2)	GB1588733A (no)
GR (1)	GR71696B (no)
HU (1)	HU174228B (no)
IE (2)	IE45225B1 (no)
IL (2)	IL52356A (no)
IT (1)	IT1237314B (no)
LU (2)	LU77588A1 (no)
NL (1)	NL189510C (no)
NO (2)	NO147447C (no)
PL (1)	PL108102B1 (no)
PT (1)	PT66690B (no)
SE (1)	SE436871B (no)
SU (1)	SU917696A3 (no)
ZA (1)	ZA773782B (no)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH626873A5 (no) *	1977-03-28	1981-12-15	Bracco Ind Chimica Spa
DK273280A (da) *	1979-06-28	1980-12-29	Schering Ag	Trijoderede 5-aminoisophthalsyrederivater
IT1193211B (it) *	1979-08-09	1988-06-15	Bracco Ind Chimica Spa	Derivati dell'acido 2,4,6-triiodo-isoftalico,metodo per la loro preparazione e mezzi di contrasto che li contengono
IT1207226B (it) *	1979-08-09	1989-05-17	Bracco Ind Chimica Spa	Derivati dell'acido 2,4,6-triiodo-isoftalico, metodo per la loro preparazione e mezzi di contrasto che li contengono.
US4341756A (en) *	1980-01-31	1982-07-27	The Regents Of The University Of California	Novel amino-dioxepane intermediates for the synthesis of new non-ionic contrast media
JPS56127373A (en) *	1980-01-31	1981-10-06	Univ California	Novel amino-dioxepane intermediate for synthesizing novel nonionic contrast agent
DE3038853A1 (de) *	1980-10-10	1982-05-27	Schering Ag, 1000 Berlin Und 4619 Bergkamen	Neue n-hydroxy-alkylierte dicarbonsaeure-bis-(3,5-dicarbamoyl-2,4,6-trijodanilide), deren herstellung und diese enthaltende roentgenkonstrastmittel (ii)
ATE20733T1 (de) *	1982-11-08	1986-08-15	Nyegaard & Co As	Roentgenkontrastmittel.
FR2541272A1 (fr) *	1983-02-23	1984-08-24	Guerbet Sa	Composes bromes et produits opacifiants en contenant
US4650903A (en) *	1984-06-21	1987-03-17	The Bf Goodrich Company	Oligomeric amides as synergists for antioxidants and UV stabilizers
DE3731542A1 (de) *	1987-09-17	1989-03-30	Schering Ag	Neue dicarbonsaeure-bis(3,5-dicarbamoyl-2,4,6-triiod-anilide), verfahren zu deren herstellung sowie diese enthaltende roentgenkontrastmittel
DE3739098A1 (de) *	1987-11-16	1989-05-24	Schering Ag	Neue substituierte dicarbonsaeure-bis(3,5-dicarbamoyl-2,4,6- trijod-anilide), verfahren zu deren herstellung sowie diese enthaltende roentgenkontrastmittel
US5075502A (en) *	1989-12-13	1991-12-24	Mallinckrodt, Inc.	Nonionic x-ray contrast agents, compositions and methods
IT1252180B (it) *	1991-12-10	1995-06-05	Bracco Ind Chimica Spa	5,5'-(1,3-propandiil) bis (imino (2-osso-2,1-etandiil)acetilimino)-bis(2,4,6-triiodo-1,3-benzendicarbossiamidi),loro metodo di preparazione e mezzi di contrasto roentgenografici che li contengono
CN1038725C (zh) *	1993-12-04	1998-06-17	吉林省鹊源国际生物工程有限公司	复方天然香菇营养液
US6149891A (en) *	1995-05-31	2000-11-21	Israel Humanitarian Foundation Ltd.	X-ray contrast medium and method for protecting against harmful effects thereof
IT1299202B1 (it) *	1998-05-08	2000-02-29	Dibra Spa	Processo per la preparazione della s-n,n'-bis (2-idrossi-1- (idrossimetil)etil) -5-((2-idrossi-1-ossopropil)ammino)-2,4,6-triiodo
US7790141B2 (en) *	2003-08-11	2010-09-07	Pathak Holdings, Llc	Radio-opaque compounds, compositions containing same and methods of their synthesis and use
NZ581765A (en)	2007-07-12	2012-03-30	Ge Healthcare As	Triiodinated compounds used in diagnostic compositions as contrast agents in diagnostic imaging
JP2011500533A (ja)	2007-10-12	2011-01-06	ジーイー・ヘルスケア・アクスイェ・セルスカプ	造影剤
EP2200971B1 (en)	2007-10-12	2013-04-24	GE Healthcare AS	Contrast agents
US20100221191A1 (en)	2007-10-12	2010-09-02	Duncan George Wynn	Contrast agents
JP2011500532A (ja)	2007-10-12	2011-01-06	ジーイー・ヘルスケア・アクスイェ・セルスカプ	造影剤
US8551449B2 (en) *	2007-10-30	2013-10-08	Ge Healthcare As	Contrast agents
US8445725B2 (en) *	2008-01-14	2013-05-21	Mallinckrodt Llc	Process for the preparation of iosimenol
WO2012136813A2 (en)	2011-04-07	2012-10-11	Universitetet I Oslo	Agents for medical radar diagnosis
EP3220887A1 (en)	2014-11-21	2017-09-27	Technical University of Denmark	Gel formulations for local drug release
MX2018014087A (es)	2016-05-20	2019-06-10	Univ Denmark Tech Dtu	Composicion de marcaje palpable.
CA3143104A1 (en)	2019-06-12	2020-12-17	Technical University Of Denmark	Dissacharide formulations for controlled drug release

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2853424A (en) *	1952-08-06	1958-09-23	Schering Ag	X-ray contrast agents comprising symmetrical bifunctional analogs of nu-acyl derivatives of 2, 4, 6 triiodo-3-amino benzoic acid
US3178473A (en) *	1962-03-02	1965-04-13	Nyegaard & Co As	Process for the n-alkylation of acyl anilides halogen substituted in the nucleus
US3290366A (en) *	1963-03-06	1966-12-06	Mallinckrodt Chemical Works	5-amino-nu-alkyl-2, 4, 6-triiodoisophthalamic acid derivatives
GB1033776A (en) *	1963-06-06	1966-06-22	Sterling Drug Inc	Iodinated acid amides and esters and salts thereof
US3732293A (en) *	1968-03-15	1973-05-08	Sterling Drug Inc	Iodinated bis(aminobenzoic acids) and esters thereof
CH502104A (de) *	1968-05-02	1971-01-31	Bracco Ind Chimica Spa	Neue Röntgenkontrastmittel und Verfahren zu ihrer Herstellung
ES381202A1 (es) *	1969-06-27	1973-04-16	Nyegaard & Co As	Un procedimiento para la preparacion de agentes de contras-te de rayos x.
US3660464A (en) *	1970-06-19	1972-05-02	Squibb & Sons Inc	Tri-iodinated diaminobenzoic acid derivatives
BE787669A (fr) *	1971-08-17	1973-02-19	Schering Ag	Anilides d'acide n-methyl-dicarboxylique triiodes, et leur procede de preparation
DD104193A5 (no) *	1972-12-22	1974-03-05
DE2629228C2 (de) *	1976-06-25	1984-10-18	Schering AG, 1000 Berlin und 4709 Bergkamen	Jodierte Isophthalamsäure-Derivate Verfahren zu deren Herstellung sowie deren Verwendung
CH626873A5 (no) *	1977-03-28	1981-12-15	Bracco Ind Chimica Spa

1976
- 1976-06-23 DE DE2628517A patent/DE2628517C2/de not_active Expired
1977
- 1977-05-18 NL NLAANVRAGE7705509,A patent/NL189510C/xx not_active IP Right Cessation
- 1977-06-16 FI FI771900A patent/FI67540C/fi not_active IP Right Cessation
- 1977-06-16 DK DK266177A patent/DK150505C/da not_active IP Right Cessation
- 1977-06-20 IE IE1249/77A patent/IE45225B1/en not_active IP Right Cessation
- 1977-06-20 PL PL1977199019A patent/PL108102B1/pl not_active IP Right Cessation
- 1977-06-20 CS CS774059A patent/CS199680B2/cs unknown
- 1977-06-20 GB GB25644/77A patent/GB1588733A/en not_active Expired
- 1977-06-20 GB GB7222/80A patent/GB1588734A/en not_active Expired
- 1977-06-21 LU LU77588A patent/LU77588A1/xx unknown
- 1977-06-21 PT PT66690A patent/PT66690B/pt unknown
- 1977-06-21 IL IL52356A patent/IL52356A/xx unknown
- 1977-06-21 CH CH761277A patent/CH629751A5/de not_active IP Right Cessation
- 1977-06-21 DD DD7700199616A patent/DD131014A5/xx unknown
- 1977-06-21 GR GR53760A patent/GR71696B/el unknown
- 1977-06-22 SU SU772498151A patent/SU917696A3/ru active
- 1977-06-22 ES ES460007A patent/ES460007A1/es not_active Expired
- 1977-06-22 NO NO772202A patent/NO147447C/no unknown
- 1977-06-22 HU HU77SCHE611A patent/HU174228B/hu unknown
- 1977-06-22 CA CA281,184A patent/CA1106400A/en not_active Expired
- 1977-06-22 SE SE7707230A patent/SE436871B/xx not_active IP Right Cessation
- 1977-06-22 AU AU26325/77A patent/AU512304B2/en not_active Expired
- 1977-06-23 FR FR7719234A patent/FR2355808A1/fr active Granted
- 1977-06-23 ZA ZA00773782A patent/ZA773782B/xx unknown
- 1977-06-23 JP JP7489777A patent/JPS537637A/ja active Granted
- 1977-06-23 AT AT443777A patent/AT361117B/de not_active IP Right Cessation
- 1977-06-23 IT IT7724994A patent/IT1237314B/it active
- 1977-06-23 BE BE178719A patent/BE856039A/xx not_active IP Right Cessation
1979
- 1979-01-12 US US06/002,901 patent/US4239747A/en not_active Expired - Lifetime
1980
- 1980-03-21 CA CA348,166A patent/CA1106401A/en not_active Expired
- 1980-06-18 IL IL60344A patent/IL60344A0/xx unknown
1981
- 1981-10-08 IE IE2351/81A patent/IE45226B1/en not_active IP Right Cessation
1982
- 1982-08-04 NO NO822674A patent/NO148811C/no unknown
1984
- 1984-12-12 DK DK595284A patent/DK165973C/da not_active IP Right Cessation
1985
- 1985-07-09 JP JP60149408A patent/JPS61126059A/ja active Granted
1993
- 1993-06-09 LU LU88292C patent/LU88292I2/de unknown

Also Published As

Publication number	Publication date
IL52356A0 (en)	1977-08-31
IT1237314B (it)	1993-05-29
NL189510B (nl)	1992-12-01
SU917696A3 (ru)	1982-03-30
AT361117B (de)	1981-02-25
IL60344A0 (en)	1980-09-16
PL199019A1 (pl)	1978-03-28
IL52356A (en)	1981-03-31
LU88292I2 (de)	1994-05-04
NL189510C (nl)	1993-05-03
CS199680B2 (en)	1980-07-31
NO822674L (no)	1977-12-27
LU77588A1 (no)	1977-09-29
NO772202L (no)	1977-12-27
DK595284D0 (da)	1984-12-12
GB1588733A (en)	1981-04-29
PT66690B (de)	1978-11-17
JPS6111220B2 (no)	1986-04-01
PL108102B1 (pl)	1980-03-31
NL7705509A (nl)	1977-12-28
FI771900A (no)	1977-12-24
CA1106401A (en)	1981-08-04
ATA443777A (de)	1980-07-15
ES460007A1 (es)	1978-05-01
US4239747A (en)	1980-12-16
IE45226L (en)	1982-07-14
NO148811B (no)	1983-09-12
BE856039A (fr)	1977-12-23
CA1106400A (en)	1981-08-04
JPS6232185B2 (no)	1987-07-13
DK165973C (da)	1993-07-26
DE2628517C2 (de)	1985-02-21
SE436871B (sv)	1985-01-28
GB1588734A (en)	1981-04-29
JPS61126059A (ja)	1986-06-13
DE2628517A1 (de)	1978-01-05
IE45225B1 (en)	1982-07-14
GR71696B (no)	1983-06-21
AU2632577A (en)	1979-01-04
HU174228B (hu)	1979-11-28
CH629751A5 (de)	1982-05-14
NO147447B (no)	1983-01-03
FR2355808A1 (fr)	1978-01-20
ZA773782B (en)	1978-05-30
DK266177A (da)	1977-12-24
NO147447C (no)	1983-04-13
IE45226B1 (en)	1982-07-14
FR2355808B1 (no)	1979-03-09
IE45225L (en)	1977-12-03
DD131014A5 (de)	1978-05-24
DK150505C (da)	1988-01-11
PT66690A (de)	1977-07-01
JPS537637A (en)	1978-01-24
AU512304B2 (en)	1980-10-02
DK150505B (da)	1987-03-16
DK595284A (da)	1984-12-12
NO148811C (no)	1983-12-21
DK165973B (da)	1993-02-22
SE7707230L (sv)	1977-12-24
FI67540B (fi)	1984-12-31

Publication	Publication Date	Title
FI67540C (fi)	1985-04-10	Nya dikarboxylsyra-bis-(3,5-dikarbamoyl-2,4,6-trijodanilid)-derivat foer anvaendning som roentgenkontrastmedel och foerfarande foer framstaellning av dessa
DE69635460T2 (de)	2006-08-10	Methode zur Hemmung des Wachstums von Bakterien oder Pilzen mit einem Komplexbildner
AU2004240213B2 (en)	2008-11-20	Polyamines and their use in therapy
CA3158293C (en)	2024-06-25	Lipid composition
JP7241869B2 (ja)	2023-03-17	脂質組成物
US4426371A (en)	1984-01-17	Novel N-hydroxyalkylated dicarboxylic acid bis(3,5-dicarbamoyl-2,4,6-triiodoanilides), as X-ray contrast media
JP2569144B2 (ja)	1997-01-08	新規ジカルボン酸ービス（３，５ージカルバモイルー２，４，６ートリヨードーアニリド）、その製法及びこれを含有するレントゲン造影剤
JP2018168165A5 (no)	2019-01-17
DK157190B (da)	1989-11-20	2,4,6-triiod-isophthalsyrederivater, fremgangsmaade til fremstilling deraf og roentgenkontrastmiddel indeholdende disse forbindelser
CZ3197A3 (en)	1997-07-16	Complexes of cascade polymers, process of their preparation and pharmaceutical composition containing thereof
FI68042B (fi)	1985-03-29	5-amino-2,4,6-trijod-isoftalsyra-bis-amid-derivat foer anvaendning i roentgenkontrastmedel
WO2008113557A2 (en)	2008-09-25	Anti-infective agents
FI93209B (fi)	1994-11-30	Substituoituja dikarboksyylihappo-bis(3,5-dikarbamoyyli-2,4,6-trijodianilideja) menetelmä niiden valmistamiseksi sekä niiden käyttö röntgenvarjoaineiden valmistamiseksi
DE4341724A1 (de)	1995-06-08	Halogenaryl-substituierte Metallkomplexe enthaltende pharmazeutische Mittel, deren Verwendung in der Diagnostik, sowie Verfahren zur Herstellung der Komplexe und Mittel
DE3218792A1 (de)	1982-12-16	Isoprenylaminderivate und deren saeureadditionssalze
JPS61140555A (ja)	1986-06-27	５−アルコキシ−２，４，６−トリヨ−ド−及びトリブロム−イソフタ−ル酸の新規誘導体、その製造法及びこれを含有するレントゲン造影剤
JP2001139497A (ja)	2001-05-22	Ｘ線造影剤
DE1965589C3 (de)	1973-09-13	Tert-Butylphenoxy-carbamido- und tert-Butylphenoxymethylen-carbamidoverbindungen, Verfahren zu deren Herstellung und dieselben enthaltende Arzneimittel
US5663413A (en)	1997-09-02	Biphenyl iodinated derivatives and their diagnostic use
JPH029584B2 (no)	1990-03-02
JPH04352785A (ja)	1992-12-07	新規メトトレキセート誘導体
JPH05229998A (ja)	1993-09-07	新規キレート化剤、該キレート化剤と金属原子との錯化合物及びそれを含む診断剤
EP0079397A1 (de)	1983-05-25	Unsymmetrisch substituierte Dicarbonsäure-bis-(2,4,-6-trijodanilide), deren Herstellung und diese enthaltende Röntgenkontrastmittel

Legal Events

Date	Code	Title	Description
1977-06-16	MA	Patent expired
2004-08-31	MA	Patent expired	Owner name: SCHERING AKTIENGESELLSCHAFT