FI117922B - Öljy-vedessä-emulsiot - Google Patents

Öljy-vedessä-emulsiot Download PDF

Info

Publication number: FI117922B
Authority: FI; Finland
Prior art keywords: oil; emulsion; pharmaceutical composition; galactolipid; water
Prior art date: 1994-02-04

Application number

FI963064A

Other languages

English (en)

Finnish (fi)

Swedish (sv)

Other versions

FI963064A (fi

FI963064A0 (fi

Inventor

Anders Carlsson

Bengt Hersloef

Marina Delogu

Original Assignee

Scotia Lipidteknik Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-02-04

Filing date

1996-08-02

Publication date

2007-04-30

1994-02-04 Priority claimed from SE9400368A external-priority patent/SE9400368D0/xx

1994-07-12 Priority claimed from SE9402454A external-priority patent/SE518823C2/sv

1996-08-02 Application filed by Scotia Lipidteknik Ab filed Critical Scotia Lipidteknik Ab

1996-08-02 Publication of FI963064A0 publication Critical patent/FI963064A0/fi

1996-09-30 Publication of FI963064A publication Critical patent/FI963064A/fi

2007-04-30 Application granted granted Critical

2007-04-30 Publication of FI117922B publication Critical patent/FI117922B/fi

Links

239000000839 emulsion Substances 0.000 title claims abstract description 94
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title claims description 61
239000000463 material Substances 0.000 claims abstract description 60
239000003995 emulsifying agent Substances 0.000 claims abstract description 51
238000002360 preparation method Methods 0.000 claims abstract description 34
239000007764 o/w emulsion Substances 0.000 claims abstract description 26
150000002632 lipids Chemical class 0.000 claims abstract description 24
239000008194 pharmaceutical composition Substances 0.000 claims abstract description 22
239000013543 active substance Substances 0.000 claims abstract description 10
235000016709 nutrition Nutrition 0.000 claims abstract description 5
239000003921 oil Substances 0.000 claims description 118
235000019198 oils Nutrition 0.000 claims description 118
239000000203 mixture Substances 0.000 claims description 34
235000020664 gamma-linolenic acid Nutrition 0.000 claims description 16
VZCCETWTMQHEPK-UHFFFAOYSA-N gamma-Linolensaeure Natural products CCCCCC=CCC=CCC=CCCCCC(O)=O VZCCETWTMQHEPK-UHFFFAOYSA-N 0.000 claims description 15
VZCCETWTMQHEPK-QNEBEIHSSA-N gamma-linolenic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/CCCCC(O)=O VZCCETWTMQHEPK-QNEBEIHSSA-N 0.000 claims description 15
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239000000126 substance Substances 0.000 claims description 9
DCXXMTOCNZCJGO-UHFFFAOYSA-N tristearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCCCCC DCXXMTOCNZCJGO-UHFFFAOYSA-N 0.000 claims description 9
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150000002431 hydrogen Chemical class 0.000 description 1
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239000003018 immunosuppressive agent Substances 0.000 description 1
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230000010354 integration Effects 0.000 description 1
230000003993 interaction Effects 0.000 description 1
QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 description 1
239000010410 layer Substances 0.000 description 1
235000010445 lecithin Nutrition 0.000 description 1
239000000787 lecithin Substances 0.000 description 1
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230000005923 long-lasting effect Effects 0.000 description 1
230000014759 maintenance of location Effects 0.000 description 1
238000005259 measurement Methods 0.000 description 1
KWKAKUADMBZCLK-UHFFFAOYSA-N methyl heptene Natural products CCCCCCC=C KWKAKUADMBZCLK-UHFFFAOYSA-N 0.000 description 1
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TVMXDCGIABBOFY-UHFFFAOYSA-N n-Octanol Natural products CCCCCCCC TVMXDCGIABBOFY-UHFFFAOYSA-N 0.000 description 1
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Classifications

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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS OR COOKING OILS
- A23D7/00—Edible oil or fat compositions containing an aqueous phase, e.g. margarines
- A23D7/005—Edible oil or fat compositions containing an aqueous phase, e.g. margarines characterised by ingredients other than fatty acid triglycerides
- A23D7/0053—Compositions other than spreads
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
- A23L33/12—Fatty acids or derivatives thereof
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L35/00—Foods or foodstuffs not provided for in groups A23L5/00 - A23L33/00; Preparation or treatment thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/06—Emulsions
- A61K8/062—Oil-in-water emulsions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/14—Liposomes; Vesicles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/829—Liposomes, e.g. encapsulation
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2984—Microcapsule with fluid core [includes liposome]

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Epidemiology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Oil, Petroleum & Natural Gas (AREA)
Molecular Biology (AREA)
Dispersion Chemistry (AREA)
Birds (AREA)
Dermatology (AREA)
Food Science & Technology (AREA)
Polymers & Plastics (AREA)
Biophysics (AREA)
Nutrition Science (AREA)
Biochemistry (AREA)
Mycology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Preparation (AREA)
Colloid Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Edible Oils And Fats (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)

FI963064A 1994-02-04 1996-08-02 Öljy-vedessä-emulsiot FI117922B (fi)

Applications Claiming Priority (6)

Application Number	Priority Date	Filing Date	Title
SE9400368A SE9400368D0 (sv)	1994-02-04	1994-02-04	Glycolipid material
SE9400368		1994-02-04
SE9402454A SE518823C2 (sv)	1994-07-12	1994-07-12	Olja-i-vatten-emulsioner
SE9402454		1994-07-12
PCT/SE1995/000115 WO1995020943A1 (en)	1994-02-04	1995-02-06	Oil-in-water emulsions
SE9500115		1995-02-06

Publications (3)

Publication Number	Publication Date
FI963064A0 FI963064A0 (fi)	1996-08-02
FI963064A FI963064A (fi)	1996-09-30
FI117922B true FI117922B (fi)	2007-04-30

Family

ID=26661954

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI963064A FI117922B (fi)	1994-02-04	1996-08-02	Öljy-vedessä-emulsiot

Country Status (24)

Country	Link
US (1)	US5688528A (de)
EP (1)	EP0797432B1 (de)
JP (1)	JP3117145B2 (de)
KR (1)	KR100193980B1 (de)
CN (1)	CN1098681C (de)
AT (1)	ATE201981T1 (de)
AU (1)	AU691248B2 (de)
BR (1)	BR9506681A (de)
CA (1)	CA2182575C (de)
CZ (1)	CZ285795B6 (de)
DE (2)	DE69521338T2 (de)
DK (1)	DK0797432T3 (de)
EE (1)	EE03220B1 (de)
ES (1)	ES2107397T3 (de)
FI (1)	FI117922B (de)
GR (1)	GR970300049T1 (de)
HU (1)	HU221477B (de)
LV (1)	LV11726B (de)
MY (1)	MY112798A (de)
NO (1)	NO312493B1 (de)
NZ (1)	NZ279952A (de)
PL (1)	PL178397B1 (de)
TW (1)	TW288979B (de)
WO (1)	WO1995020943A1 (de)

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US20030215473A1 (en) *	1998-03-06	2003-11-20	Anders Carlsson	Topical formulation of oil-in-water type as a carrier for providing a reduced irritant effect
SE9800729L (sv) *	1998-03-06	1999-09-07	Scotia Lipidteknik Ab	Ny topikal formulering I
US20050063930A1 (en) *	1998-03-06	2005-03-24	Anders Carlsson	Topical formulation of the oil-in-water type, comprising galactolipid material as emulsifier, with a prolonged effect of an incorporated active substance
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GB0012597D0 (en) *	2000-05-25	2000-07-12	Astrazeneca Ab	Formulation
AU2002256879A1 (en) *	2002-04-17	2003-10-27	Agribiotec S.R.L.	Use of vegetable oil as an adjuvant for substances having a fungicide, bactericide, insecticide and herbicide activity
SE0300207D0 (sv)	2003-01-29	2003-01-29	Karolinska Innovations Ab	New use and composition
EP1667698B1 (de)	2003-05-22	2009-03-18	Bioniche Life Sciences Inc.	Insektenabwehrmittel
EP1846444A2 (de)	2004-12-22	2007-10-24	Lipopeptide AB	Das cathelinähnliche protein cap18/ll-37 hemmende mittel
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US20090069445A1 (en) *	2005-04-13	2009-03-12	Otsuka Pharmaceutical Factory, Inc	Propofol-containing fat emulsions
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DE102005023636A1 (de) *	2005-05-19	2006-11-23	Beiersdorf Ag	Wirkstoffkombinationen aus Glucosylglyceriden und Kreatin und / oder Kreatinin
DE102005023638A1 (de) *	2005-05-19	2006-11-23	Beiersdorf Ag	Kosmetische Zubereitungen mit einem Gehalt an Glucosylglyceriden und einem oder mehreren Acrylamidomethylpropylsulfonsäure-Polymeren
PT1800675E (pt) *	2005-12-23	2011-08-30	Nutricia Nv	COMPOSIÇÃO CONTENDO ÁCIDOS GORDOS POLI-INSATURADOS, PROTEÍNAS E MANGANjS E/OU MOLIBDÉNIO PARA O MELHORAMENTO DA COMPOSIÇÃO DA MEMBRANA
US20080058418A1 (en) *	2006-09-06	2008-03-06	The Coca-Cola Company	Stable polyunsaturated fatty acid emulsions and methods for inhibiting, suppressing, or reducing degradation of polyunsaturated fatty acids in an emulsion
US20090018186A1 (en) *	2006-09-06	2009-01-15	The Coca-Cola Company	Stable beverage products comprising polyunsaturated fatty acid emulsions
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US20090137497A1 (en) *	2007-11-23	2009-05-28	Beiersdorf Ag	Active ingredient combinations of glucosyl glycerides and creatine and/or creatinine
WO2009068651A1 (en) *	2007-11-28	2009-06-04	Dsm Ip Assets B.V.	Lipid emulsion for human consumption
ES2582563T3 (es) *	2008-01-18	2016-09-13	Dsm Ip Assets B.V.	Emulsión secada por pulverización
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1995
- 1995-02-06 KR KR1019960704237A patent/KR100193980B1/ko not_active IP Right Cessation
- 1995-02-06 AT AT95909183T patent/ATE201981T1/de not_active IP Right Cessation
- 1995-02-06 WO PCT/SE1995/000115 patent/WO1995020943A1/en active IP Right Grant
- 1995-02-06 DE DE69521338T patent/DE69521338T2/de not_active Expired - Lifetime
- 1995-02-06 ES ES95909183T patent/ES2107397T3/es not_active Expired - Lifetime
- 1995-02-06 EP EP95909183A patent/EP0797432B1/de not_active Expired - Lifetime
- 1995-02-06 NZ NZ279952A patent/NZ279952A/en unknown
- 1995-02-06 CA CA002182575A patent/CA2182575C/en not_active Expired - Fee Related
- 1995-02-06 HU HU9602141A patent/HU221477B/hu not_active IP Right Cessation
- 1995-02-06 AU AU17233/95A patent/AU691248B2/en not_active Ceased
- 1995-02-06 CN CN95191500A patent/CN1098681C/zh not_active Expired - Fee Related
- 1995-02-06 DE DE0797432T patent/DE797432T1/de active Pending
- 1995-02-06 DK DK95909183T patent/DK0797432T3/da active
- 1995-02-06 MY MYPI95000256A patent/MY112798A/en unknown
- 1995-02-06 CZ CZ962215A patent/CZ285795B6/cs not_active IP Right Cessation
- 1995-02-06 EE EE9600087A patent/EE03220B1/xx not_active IP Right Cessation
- 1995-02-06 JP JP07520555A patent/JP3117145B2/ja not_active Expired - Fee Related
- 1995-02-06 BR BR9506681A patent/BR9506681A/pt not_active IP Right Cessation
- 1995-02-06 US US08/676,138 patent/US5688528A/en not_active Expired - Lifetime
- 1995-02-06 PL PL95315778A patent/PL178397B1/pl not_active IP Right Cessation
- 1995-02-13 TW TW084101257A patent/TW288979B/zh active
1996
- 1996-08-02 LV LVP-96-323A patent/LV11726B/en unknown
- 1996-08-02 FI FI963064A patent/FI117922B/fi active IP Right Grant
- 1996-08-02 NO NO19963240A patent/NO312493B1/no not_active IP Right Cessation
1998
- 1998-01-30 GR GR970300049T patent/GR970300049T1/el unknown

Also Published As

Publication number	Publication date
DE69521338D1 (de)	2001-07-19
HUT75464A (en)	1997-05-28
PL178397B1 (pl)	2000-04-28
AU1723395A (en)	1995-08-21
CN1098681C (zh)	2003-01-15
ES2107397T3 (es)	2001-10-01
NO963240D0 (no)	1996-08-02
NZ279952A (en)	1998-02-26
DE69521338T2 (de)	2002-02-28
EE03220B1 (et)	1999-10-15
AU691248B2 (en)	1998-05-14
TW288979B (de)	1996-10-21
ATE201981T1 (de)	2001-06-15
DK0797432T3 (da)	2001-09-03
BR9506681A (pt)	1997-11-18
LV11726B (en)	1997-10-20
HU221477B (en)	2002-10-28
LV11726A (lv)	1997-04-20
CN1140406A (zh)	1997-01-15
CA2182575A1 (en)	1995-08-10
EP0797432A1 (de)	1997-10-01
CZ285795B6 (cs)	1999-11-17
JPH09508413A (ja)	1997-08-26
JP3117145B2 (ja)	2000-12-11
NO312493B1 (no)	2002-05-21
CA2182575C (en)	2000-11-28
FI963064A (fi)	1996-09-30
HU9602141D0 (en)	1996-09-30
GR970300049T1 (en)	1998-01-30
FI963064A0 (fi)	1996-08-02
US5688528A (en)	1997-11-18
MY112798A (en)	2001-09-29
EP0797432B1 (de)	2001-06-13
CZ221596A3 (en)	1996-11-13
NO963240L (no)	1996-08-02
WO1995020943A1 (en)	1995-08-10
ES2107397T1 (es)	1997-12-01
KR100193980B1 (ko)	1999-06-15
DE797432T1 (de)	1998-02-19
PL315778A1 (en)	1996-12-09

Publication	Publication Date	Title
FI117922B (fi)	2007-04-30	Öljy-vedessä-emulsiot
KR100220546B1 (ko)	1999-09-15	호지성 담체 제제
CA2182576C (en)	2002-09-17	Bilayer preparations
US6355693B1 (en)	2002-03-12	Fractionated vegetable oil
AU764413B2 (en)	2003-08-21	A pharmaceutical composition comprising cyclosporin in a lipid carrier
RU2131266C1 (ru)	1999-06-10	Эмульсия типа "масло в воде", носитель на ее основе и фармацевтическая композиция
MXPA96003038A (en)	1998-01-01	Oil emulsions in a

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