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ES8707260A1 - Procedimiento para preparar derivados de aminoacidos - Google Patents

Procedimiento para preparar derivados de aminoacidos

Info

Publication number
ES8707260A1
ES8707260A1 ES555392A ES555392A ES8707260A1 ES 8707260 A1 ES8707260 A1 ES 8707260A1 ES 555392 A ES555392 A ES 555392A ES 555392 A ES555392 A ES 555392A ES 8707260 A1 ES8707260 A1 ES 8707260A1
Authority
ES
Spain
Prior art keywords
alkyl
phenyl
image
branched
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES555392A
Other languages
English (en)
Other versions
ES555392A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim GmbH
Original Assignee
Boehringer Ingelheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim GmbH filed Critical Boehringer Ingelheim GmbH
Publication of ES8707260A1 publication Critical patent/ES8707260A1/es
Publication of ES555392A0 publication Critical patent/ES555392A0/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06017Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

PROCEIDMIENTO PARA LA PREPARACION DE DERIVADOS DE AMINOACIDOS, DE FORMULA GENERAL (I), Y SUS SALES FARMACEUTICAMENTE ACEPTABLES. CONSISTE EN TRANSFORMAR UN COMPUESTO DE FORMULA GENERAL (I), EN LA QUE R2 ES HIDROGENO, POR REACCION CON UN COMPUESTO: B-R2, EN LA QUE R2 TIENE UN SIGNIFICADO DISTINTO DEL DE HIDROGENO Y B SIGNIFICA UN GRUPO FACILMENTE SEPARABLE, POR EJEMPLO CLORO O BROMO, EN UN COMPUESTO DE FORMULA GENERAL (I). DICHA REACCION SE LLEVA A EFECTO EN PRESENCIA DE UN AGENTE FIJADOR DE ACIDOS. DE APLICACION COMO AGENTES HIPOTENSORES PARA LA PREPARACION DE COMPOSICIONES FARMACEUTICAS UTILIZADAS COMO MEDICAMENTOS.
ES555392A 1984-09-03 1986-05-28 Procedimiento para preparar derivados de aminoacidos Expired ES8707260A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843432307 DE3432307A1 (de) 1984-09-03 1984-09-03 Aminosaeurederivate, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen

Publications (2)

Publication Number Publication Date
ES8707260A1 true ES8707260A1 (es) 1987-07-01
ES555392A0 ES555392A0 (es) 1987-07-01

Family

ID=6244509

Family Applications (7)

Application Number Title Priority Date Filing Date
ES546649A Expired ES8704183A1 (es) 1984-09-03 1985-09-02 Procedimiento para preparar derivados de aminoacidos
ES555388A Expired ES8706720A1 (es) 1984-09-03 1986-05-28 Procedimiento para preparar derivados de aminoacidos
ES555393A Expired ES8800895A1 (es) 1984-09-03 1986-05-28 Procedimiento para preparar compuestos dimeros de derivados de aminoacidos.
ES555389A Expired ES8707257A1 (es) 1984-09-03 1986-05-28 Procedimiento para preparar derivados de aminoacidos
ES555391A Expired ES8707259A1 (es) 1984-09-03 1986-05-28 Procedimiento para preparar derivados de aminoacidos
ES555392A Expired ES8707260A1 (es) 1984-09-03 1986-05-28 Procedimiento para preparar derivados de aminoacidos
ES555390A Expired ES8707258A1 (es) 1984-09-03 1986-05-28 Procedimiento para preparar derivados de aminoacidos

Family Applications Before (5)

Application Number Title Priority Date Filing Date
ES546649A Expired ES8704183A1 (es) 1984-09-03 1985-09-02 Procedimiento para preparar derivados de aminoacidos
ES555388A Expired ES8706720A1 (es) 1984-09-03 1986-05-28 Procedimiento para preparar derivados de aminoacidos
ES555393A Expired ES8800895A1 (es) 1984-09-03 1986-05-28 Procedimiento para preparar compuestos dimeros de derivados de aminoacidos.
ES555389A Expired ES8707257A1 (es) 1984-09-03 1986-05-28 Procedimiento para preparar derivados de aminoacidos
ES555391A Expired ES8707259A1 (es) 1984-09-03 1986-05-28 Procedimiento para preparar derivados de aminoacidos

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES555390A Expired ES8707258A1 (es) 1984-09-03 1986-05-28 Procedimiento para preparar derivados de aminoacidos

Country Status (19)

Country Link
EP (1) EP0174571A3 (es)
JP (1) JPS6183199A (es)
KR (1) KR860002463A (es)
AU (1) AU4702285A (es)
CS (1) CS254345B2 (es)
DD (1) DD240547A5 (es)
DE (1) DE3432307A1 (es)
DK (1) DK400085A (es)
ES (7) ES8704183A1 (es)
FI (1) FI853354L (es)
GR (1) GR852112B (es)
HU (1) HUT39191A (es)
IL (1) IL76282A0 (es)
NO (1) NO853444L (es)
NZ (1) NZ213317A (es)
PL (1) PL255220A1 (es)
PT (1) PT81078B (es)
SU (1) SU1468411A3 (es)
ZA (1) ZA856691B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3705656A1 (de) * 1987-02-21 1988-09-01 Boehringer Ingelheim Kg Aminosaeurederivate, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen
DE3731085A1 (de) * 1987-09-16 1989-04-06 Hoechst Ag Neue aminosaeureester, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
DE102006004063A1 (de) * 2006-01-28 2007-08-02 Degussa Gmbh Verfahren zur Herstellung von Methionin aus Homoserin

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU537592B2 (en) * 1979-04-02 1984-07-05 E.R. Squibb & Sons, Inc. Mercaptoacyldipeptides
EP0065301A1 (en) * 1981-05-18 1982-11-24 Merck & Co. Inc. Isoquinoline carboxylic acid derivates, process for preparing and pharmaceutical composition containing the same
IT1195287B (it) * 1981-11-05 1988-10-12 Ausonia Farma Srl Derivato tiazolico,procedimento per la sua preparazione e relative composizioni farmaceutiche
DE3243370A1 (de) * 1982-11-24 1984-05-24 Basf Ag, 6700 Ludwigshafen Benzoylthioverbindungen, ihre herstellung und verwendung als arzneimittel
DE3302125A1 (de) * 1983-01-22 1984-07-26 Boehringer Ingelheim KG, 6507 Ingelheim Aminosaeure-derivate, verfahren zu ihrer herstellung und verwendung

Also Published As

Publication number Publication date
ES8707257A1 (es) 1987-07-01
EP0174571A3 (de) 1989-01-11
SU1468411A3 (ru) 1989-03-23
FI853354L (fi) 1986-03-04
ZA856691B (en) 1987-05-27
ES546649A0 (es) 1987-03-16
DE3432307A1 (de) 1986-04-10
DK400085A (da) 1986-03-04
ES555392A0 (es) 1987-07-01
NO853444L (no) 1986-03-04
ES555390A0 (es) 1987-07-01
NZ213317A (en) 1987-11-27
ES8707259A1 (es) 1987-07-01
ES8706720A1 (es) 1987-07-01
ES555388A0 (es) 1987-07-01
ES8704183A1 (es) 1987-03-16
ES8707258A1 (es) 1987-07-01
CS254345B2 (en) 1988-01-15
AU4702285A (en) 1986-03-13
PT81078B (de) 1987-07-10
GR852112B (es) 1985-12-24
ES8800895A1 (es) 1987-12-01
HUT39191A (en) 1986-08-28
ES555391A0 (es) 1987-07-01
PL255220A1 (en) 1988-03-31
FI853354A0 (fi) 1985-09-02
DK400085D0 (da) 1985-09-02
PT81078A (de) 1985-10-01
KR860002463A (ko) 1986-04-26
DD240547A5 (de) 1986-11-05
ES555389A0 (es) 1987-07-01
EP0174571A2 (de) 1986-03-19
JPS6183199A (ja) 1986-04-26
ES555393A0 (es) 1987-12-01
IL76282A0 (en) 1986-01-31
CS624285A2 (en) 1987-06-11

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