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ES8604521A1 - Procedimiento para la obtencion de acidos quinolona- o bien naftiridona-carboxilicos - Google Patents

Procedimiento para la obtencion de acidos quinolona- o bien naftiridona-carboxilicos

Info

Publication number
ES8604521A1
ES8604521A1 ES545081A ES545081A ES8604521A1 ES 8604521 A1 ES8604521 A1 ES 8604521A1 ES 545081 A ES545081 A ES 545081A ES 545081 A ES545081 A ES 545081A ES 8604521 A1 ES8604521 A1 ES 8604521A1
Authority
ES
Spain
Prior art keywords
preparation
acids
naphthyridoncarboxylic
quinolinone
quinolone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES545081A
Other languages
English (en)
Other versions
ES545081A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of ES8604521A1 publication Critical patent/ES8604521A1/es
Publication of ES545081A0 publication Critical patent/ES545081A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • C07C201/06—Preparation of nitro compounds
    • C07C201/12—Preparation of nitro compounds by reactions not involving the formation of nitro groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/58—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems with hetero atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PROCEDIMIENTE PARA LA OBTENCION DE ACIDOS QUINOLONA- O BIEN NAFTIRIDONACARBOXILICOS. CONSISTE EN CICLOCONDENSAR DERIVADOS DEL ACIDO AMINOACRILICO DE FORMULA (III) PARA OBTENER COMPUESTO DE FORMULA (II) Y SAPONIFICAR EL GRUPO ALCOXICARBONILO R2, PARA OBTENER ACIDOS QUINOLONA O NAFTIRIDONACARBOXILICOS DE FORMULA (I). LA CICLOCONEDENSACION SE LLEVA A CABO EN PRESENCIA DE UN DILUYENTE COMO DIOXANO, DIMETILSULFOXIDO, N-METILPIRROLIDONA Y OTROS, Y A TEMPERATURAS COMPRENDIDAS ENTRE 60 Y 300JC Y EMPLEANDOSE COMO AGENTE DE CONDENSACION PARA LA CICLOCONDENSACION CARBONATO SODICO O POTASICO. TIENEN APLICACIONES FARMACOLOGICAS COMO PRODUCTOS INTERMEDIOS PARA LA SINTESIS DE MEDICAMENTOS ANTIBACTERIANOS.
ES545081A 1984-07-18 1985-07-11 Procedimiento para la obtencion de acidos quinolona- o bien naftiridona-carboxilicos Expired ES8604521A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3426486A DE3426486A1 (de) 1984-07-18 1984-07-18 Verfahren zur herstellung von chinolon- und naphthyridoncarbonsaeuren

Publications (2)

Publication Number Publication Date
ES8604521A1 true ES8604521A1 (es) 1986-02-01
ES545081A0 ES545081A0 (es) 1986-02-01

Family

ID=6240970

Family Applications (1)

Application Number Title Priority Date Filing Date
ES545081A Expired ES8604521A1 (es) 1984-07-18 1985-07-11 Procedimiento para la obtencion de acidos quinolona- o bien naftiridona-carboxilicos

Country Status (10)

Country Link
EP (1) EP0168733A3 (es)
JP (1) JPS6144866A (es)
KR (1) KR910003617B1 (es)
DD (1) DD236523A5 (es)
DE (1) DE3426486A1 (es)
DK (1) DK325585A (es)
ES (1) ES8604521A1 (es)
HU (1) HU195643B (es)
IL (1) IL75811A (es)
ZA (1) ZA855389B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3501247A1 (de) * 1985-01-16 1986-07-17 Bayer Ag, 5090 Leverkusen Aminoacrylsaeure-derivate
US4772706A (en) * 1986-01-13 1988-09-20 Warner-Lambert Company Process for quinoline-3-carboxylic acid antibacterial agents
DE3615767A1 (de) * 1986-05-10 1987-11-12 Bayer Ag Verfahren zur herstellung von 4-hydroxy-chinolin-3-carbonsaeuren
EP0259804B1 (de) * 1986-09-12 1993-11-18 F. Hoffmann-La Roche Ag Pyrido [3,2,1-ij]-1,3,4-benzoxadiazinderivate, Verfahren zu deren Herstellung, entsprechende pharmazeutische Präparate und im Verfahren verwendbare Zwischenprodukte
DE3724466A1 (de) * 1987-07-24 1989-02-02 Bayer Ag Verfahren zur herstellung von chinoloncarbonsaeuren
WO1992010176A1 (en) * 1990-12-07 1992-06-25 Taisho Pharmaceutical Co., Ltd. Therapeutic agent for hepatic disease

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2808070A1 (de) * 1978-02-24 1979-08-30 Bayer Ag Verfahren zur herstellung von 4-pyridon-3-carbonsaeuren und/oder deren derivaten

Also Published As

Publication number Publication date
KR910003617B1 (ko) 1991-06-07
HUT38912A (en) 1986-07-28
EP0168733A2 (de) 1986-01-22
IL75811A0 (en) 1985-11-29
IL75811A (en) 1988-05-31
ZA855389B (en) 1986-02-26
DE3426486A1 (de) 1986-01-30
DK325585D0 (da) 1985-07-17
DK325585A (da) 1986-01-19
JPS6144866A (ja) 1986-03-04
DD236523A5 (de) 1986-06-11
EP0168733A3 (de) 1987-08-26
HU195643B (en) 1988-06-28
KR860001071A (ko) 1986-02-22
ES545081A0 (es) 1986-02-01

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