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ES8407047A1 - Carboline derivatives. - Google Patents

Carboline derivatives.

Info

Publication number
ES8407047A1
ES8407047A1 ES522458A ES522458A ES8407047A1 ES 8407047 A1 ES8407047 A1 ES 8407047A1 ES 522458 A ES522458 A ES 522458A ES 522458 A ES522458 A ES 522458A ES 8407047 A1 ES8407047 A1 ES 8407047A1
Authority
ES
Spain
Prior art keywords
carboline derivatives
chem
formula
carboline
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES522458A
Other languages
Spanish (es)
Other versions
ES522458A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of ES522458A0 publication Critical patent/ES522458A0/en
Publication of ES8407047A1 publication Critical patent/ES8407047A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Carboline derivatives of the formula: < CHEM > where X is H, F, Cl or Br, Z is H, F, Cl or -OCH3, and R is < CHEM > where Y is H, CH3, F or Cl, and their use in preparing tranquilizing agents of the formula: < CHEM > wherein X, Z and R are as defined above.
ES522458A 1982-05-17 1983-05-16 Carboline derivatives. Expired ES8407047A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/378,945 US4451655A (en) 1982-05-17 1982-05-17 Process for preparing carboline derivatives and compounds used in their preparation

Publications (2)

Publication Number Publication Date
ES522458A0 ES522458A0 (en) 1984-08-16
ES8407047A1 true ES8407047A1 (en) 1984-08-16

Family

ID=23495180

Family Applications (1)

Application Number Title Priority Date Filing Date
ES522458A Expired ES8407047A1 (en) 1982-05-17 1983-05-16 Carboline derivatives.

Country Status (12)

Country Link
US (1) US4451655A (en)
EP (1) EP0094774A3 (en)
JP (1) JPS58210082A (en)
KR (1) KR840004752A (en)
AU (1) AU535954B2 (en)
DK (1) DK216983A (en)
ES (1) ES8407047A1 (en)
FI (1) FI831707L (en)
GR (1) GR77497B (en)
IL (1) IL68707A0 (en)
PL (1) PL241936A1 (en)
PT (1) PT76698B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107445886B (en) * 2017-05-24 2020-02-21 北京八亿时空液晶科技股份有限公司 Preparation method of high-purity 3-bromo-9-phenylcarbazole

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2819997A (en) * 1958-01-14 Quaternary salt derivatives of harman
US4001263A (en) * 1974-04-01 1977-01-04 Pfizer Inc. 5-Aryl-1,2,3,4-tetrahydro-γ-carbolines
AR207799A1 (en) * 1974-04-01 1976-10-29 Pfizer PROCEDURE TO PREPARE AZACICLO (3,4-A) -N-PHENYLINDOLES-2-SUBSTITUTE
US4224329A (en) * 1979-01-23 1980-09-23 Pfizer Inc. 2-Substituted-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles
SE441448B (en) * 1977-05-23 1985-10-07 Pfizer SET TO MAKE HEXAHYDRO-GAMMA CARBOL COMPOUNDS

Also Published As

Publication number Publication date
ES522458A0 (en) 1984-08-16
PT76698A (en) 1983-06-01
US4451655A (en) 1984-05-29
IL68707A0 (en) 1983-09-30
EP0094774A3 (en) 1984-12-19
PT76698B (en) 1986-03-27
FI831707L (en) 1983-11-18
DK216983D0 (en) 1983-05-16
AU535954B2 (en) 1984-04-12
KR840004752A (en) 1984-10-24
AU1456483A (en) 1983-11-24
JPS58210082A (en) 1983-12-07
FI831707A0 (en) 1983-05-16
DK216983A (en) 1983-11-18
GR77497B (en) 1984-09-24
PL241936A1 (en) 1984-07-30
EP0094774A2 (en) 1983-11-23

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20000403