ES8406436A1 - Procedimiento para la obtencion de derivados de la pirrolidina - Google Patents
Procedimiento para la obtencion de derivados de la pirrolidinaInfo
- Publication number
- ES8406436A1 ES8406436A1 ES527897A ES527897A ES8406436A1 ES 8406436 A1 ES8406436 A1 ES 8406436A1 ES 527897 A ES527897 A ES 527897A ES 527897 A ES527897 A ES 527897A ES 8406436 A1 ES8406436 A1 ES 8406436A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- radical
- alkoxy
- atom
- pyrrolidine derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Luminescent Compositions (AREA)
- Steroid Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE PIRROLIDINA Y DE SUS SALES DE ADICION DE ACIDOS, DE FORMULA (I), EN LA QUE X ES OXIGENO O AZUFRE; R ES HIDROGENO O ALQUILO; RO E Y PUEDEN SER VARIOS RADICALES; Y N Y P VALEN 0 O 1 Y 1-3, RESPECTIVAMENTE.CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA (II) CON UNA PIRROLIDINA-2, DE FORMULA (III), EN LAS QUE R1 ES ALQUILO Y LOS DEMAS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). SI X ES AZUFRE, EL PRODUCTO ANTES OBTENIDO SE TRANSFORMA EN EL DESEADO POR TIONACION.ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS COMOANTIDEPRESORES.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8220492A FR2537133A1 (fr) | 1982-12-07 | 1982-12-07 | Nouveaux derives de la (piperazinyl-1)-5 pyrrolidine, leur preparation et les medicaments qui les contiennent |
Publications (2)
Publication Number | Publication Date |
---|---|
ES527897A0 ES527897A0 (es) | 1984-08-01 |
ES8406436A1 true ES8406436A1 (es) | 1984-08-01 |
Family
ID=9279863
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES527897A Expired ES8406436A1 (es) | 1982-12-07 | 1983-12-07 | Procedimiento para la obtencion de derivados de la pirrolidina |
Country Status (25)
Country | Link |
---|---|
US (1) | US4547504A (es) |
EP (1) | EP0110795B1 (es) |
JP (1) | JPS59110670A (es) |
AT (1) | ATE18548T1 (es) |
AU (1) | AU560075B2 (es) |
BG (1) | BG40808A3 (es) |
CA (1) | CA1208645A (es) |
CS (1) | CS240982B2 (es) |
DD (1) | DD213216A5 (es) |
DE (1) | DE3362566D1 (es) |
DK (1) | DK562783A (es) |
ES (1) | ES8406436A1 (es) |
FI (1) | FI76320C (es) |
FR (1) | FR2537133A1 (es) |
GR (1) | GR72855B (es) |
HU (1) | HU191903B (es) |
IE (1) | IE56453B1 (es) |
IL (1) | IL70396A (es) |
MA (1) | MA19966A1 (es) |
NO (1) | NO158218C (es) |
NZ (1) | NZ206498A (es) |
PL (1) | PL141385B1 (es) |
PT (1) | PT77774B (es) |
SU (1) | SU1240359A3 (es) |
ZA (1) | ZA839070B (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA871335B (en) * | 1986-02-27 | 1987-09-30 | Duphar Int Res | New aryl-substituted(n-piperidinyl)methyl-and(n-piperazinyl)-methylazoles having antipsychotic properties |
US5066663A (en) * | 1990-05-21 | 1991-11-19 | Warner-Lambert Company | Substituted-hetero-cyclopentanones and cyclopentenones and derivatives thereof acting at muscarinic receptors |
US6897213B1 (en) | 1995-11-21 | 2005-05-24 | Warner-Lambert Company | Heterocycles as cholecystokinin (CCK) ligands |
US5969138A (en) * | 1996-11-01 | 1999-10-19 | Mitsui Chemicals, Inc. | Pyrrolidinone derivatives |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4247549A (en) * | 1978-12-27 | 1981-01-27 | Ici Americas Inc. | Piperazine-1-carboxylic acid esters possessing antidepressant or analgesic activity |
-
1982
- 1982-12-07 FR FR8220492A patent/FR2537133A1/fr active Granted
-
1983
- 1983-12-02 CS CS839041A patent/CS240982B2/cs unknown
- 1983-12-05 PL PL1983244921A patent/PL141385B1/pl unknown
- 1983-12-05 DD DD83257518A patent/DD213216A5/de unknown
- 1983-12-05 FI FI834453A patent/FI76320C/fi not_active IP Right Cessation
- 1983-12-05 GR GR73154A patent/GR72855B/el unknown
- 1983-12-06 PT PT77774A patent/PT77774B/pt unknown
- 1983-12-06 MA MA20187A patent/MA19966A1/fr unknown
- 1983-12-06 CA CA000442681A patent/CA1208645A/fr not_active Expired
- 1983-12-06 IL IL70396A patent/IL70396A/xx not_active IP Right Cessation
- 1983-12-06 AT AT83402354T patent/ATE18548T1/de not_active IP Right Cessation
- 1983-12-06 NZ NZ206498A patent/NZ206498A/en unknown
- 1983-12-06 SU SU833673511A patent/SU1240359A3/ru active
- 1983-12-06 JP JP58229251A patent/JPS59110670A/ja active Pending
- 1983-12-06 HU HU834166A patent/HU191903B/hu unknown
- 1983-12-06 AU AU22108/83A patent/AU560075B2/en not_active Ceased
- 1983-12-06 ZA ZA839070A patent/ZA839070B/xx unknown
- 1983-12-06 US US06/558,775 patent/US4547504A/en not_active Expired - Fee Related
- 1983-12-06 DE DE8383402354T patent/DE3362566D1/de not_active Expired
- 1983-12-06 NO NO834481A patent/NO158218C/no unknown
- 1983-12-06 DK DK562783A patent/DK562783A/da not_active Application Discontinuation
- 1983-12-06 EP EP83402354A patent/EP0110795B1/fr not_active Expired
- 1983-12-06 IE IE2867/83A patent/IE56453B1/xx unknown
- 1983-12-07 BG BG063371A patent/BG40808A3/xx unknown
- 1983-12-07 ES ES527897A patent/ES8406436A1/es not_active Expired
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