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ES8406436A1 - Procedimiento para la obtencion de derivados de la pirrolidina - Google Patents

Procedimiento para la obtencion de derivados de la pirrolidina

Info

Publication number
ES8406436A1
ES8406436A1 ES527897A ES527897A ES8406436A1 ES 8406436 A1 ES8406436 A1 ES 8406436A1 ES 527897 A ES527897 A ES 527897A ES 527897 A ES527897 A ES 527897A ES 8406436 A1 ES8406436 A1 ES 8406436A1
Authority
ES
Spain
Prior art keywords
alkyl
radical
alkoxy
atom
pyrrolidine derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES527897A
Other languages
English (en)
Other versions
ES527897A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Sante SA
Original Assignee
Rhone Poulenc Sante SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Sante SA filed Critical Rhone Poulenc Sante SA
Publication of ES527897A0 publication Critical patent/ES527897A0/es
Publication of ES8406436A1 publication Critical patent/ES8406436A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • C07D207/262-Pyrrolidones
    • C07D207/2732-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Luminescent Compositions (AREA)
  • Steroid Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE PIRROLIDINA Y DE SUS SALES DE ADICION DE ACIDOS, DE FORMULA (I), EN LA QUE X ES OXIGENO O AZUFRE; R ES HIDROGENO O ALQUILO; RO E Y PUEDEN SER VARIOS RADICALES; Y N Y P VALEN 0 O 1 Y 1-3, RESPECTIVAMENTE.CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA (II) CON UNA PIRROLIDINA-2, DE FORMULA (III), EN LAS QUE R1 ES ALQUILO Y LOS DEMAS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). SI X ES AZUFRE, EL PRODUCTO ANTES OBTENIDO SE TRANSFORMA EN EL DESEADO POR TIONACION.ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS COMOANTIDEPRESORES.
ES527897A 1982-12-07 1983-12-07 Procedimiento para la obtencion de derivados de la pirrolidina Expired ES8406436A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8220492A FR2537133A1 (fr) 1982-12-07 1982-12-07 Nouveaux derives de la (piperazinyl-1)-5 pyrrolidine, leur preparation et les medicaments qui les contiennent

Publications (2)

Publication Number Publication Date
ES527897A0 ES527897A0 (es) 1984-08-01
ES8406436A1 true ES8406436A1 (es) 1984-08-01

Family

ID=9279863

Family Applications (1)

Application Number Title Priority Date Filing Date
ES527897A Expired ES8406436A1 (es) 1982-12-07 1983-12-07 Procedimiento para la obtencion de derivados de la pirrolidina

Country Status (25)

Country Link
US (1) US4547504A (es)
EP (1) EP0110795B1 (es)
JP (1) JPS59110670A (es)
AT (1) ATE18548T1 (es)
AU (1) AU560075B2 (es)
BG (1) BG40808A3 (es)
CA (1) CA1208645A (es)
CS (1) CS240982B2 (es)
DD (1) DD213216A5 (es)
DE (1) DE3362566D1 (es)
DK (1) DK562783A (es)
ES (1) ES8406436A1 (es)
FI (1) FI76320C (es)
FR (1) FR2537133A1 (es)
GR (1) GR72855B (es)
HU (1) HU191903B (es)
IE (1) IE56453B1 (es)
IL (1) IL70396A (es)
MA (1) MA19966A1 (es)
NO (1) NO158218C (es)
NZ (1) NZ206498A (es)
PL (1) PL141385B1 (es)
PT (1) PT77774B (es)
SU (1) SU1240359A3 (es)
ZA (1) ZA839070B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA871335B (en) * 1986-02-27 1987-09-30 Duphar Int Res New aryl-substituted(n-piperidinyl)methyl-and(n-piperazinyl)-methylazoles having antipsychotic properties
US5066663A (en) * 1990-05-21 1991-11-19 Warner-Lambert Company Substituted-hetero-cyclopentanones and cyclopentenones and derivatives thereof acting at muscarinic receptors
US6897213B1 (en) 1995-11-21 2005-05-24 Warner-Lambert Company Heterocycles as cholecystokinin (CCK) ligands
US5969138A (en) * 1996-11-01 1999-10-19 Mitsui Chemicals, Inc. Pyrrolidinone derivatives

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4247549A (en) * 1978-12-27 1981-01-27 Ici Americas Inc. Piperazine-1-carboxylic acid esters possessing antidepressant or analgesic activity

Also Published As

Publication number Publication date
US4547504A (en) 1985-10-15
BG40808A3 (en) 1987-02-16
FI834453A0 (fi) 1983-12-05
IL70396A (en) 1986-11-30
ATE18548T1 (de) 1986-03-15
CA1208645A (fr) 1986-07-29
ZA839070B (en) 1984-07-25
IE56453B1 (en) 1991-08-14
PL244921A1 (en) 1985-03-26
SU1240359A3 (ru) 1986-06-23
AU2210883A (en) 1984-06-14
HU191903B (en) 1987-04-28
PT77774A (fr) 1984-01-01
PL141385B1 (en) 1987-07-31
ES527897A0 (es) 1984-08-01
FR2537133A1 (fr) 1984-06-08
EP0110795B1 (fr) 1986-03-12
FI76320C (fi) 1988-10-10
DE3362566D1 (en) 1986-04-17
FI76320B (fi) 1988-06-30
CS904183A2 (en) 1985-06-13
IE832867L (en) 1984-06-07
DK562783A (da) 1984-06-08
MA19966A1 (fr) 1984-07-01
GR72855B (es) 1983-12-08
CS240982B2 (en) 1986-03-13
JPS59110670A (ja) 1984-06-26
EP0110795A1 (fr) 1984-06-13
PT77774B (fr) 1986-07-11
DK562783D0 (da) 1983-12-06
IL70396A0 (en) 1984-03-30
DD213216A5 (de) 1984-09-05
AU560075B2 (en) 1987-03-26
NO158218B (no) 1988-04-25
NO158218C (no) 1988-08-03
NZ206498A (en) 1986-05-09
FR2537133B1 (es) 1985-05-17
NO834481L (no) 1984-06-08
FI834453A (fi) 1984-06-08

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