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ES8306124A1 - Procedimiento para la obtencion de derivados de imidazol trisustituidos. - Google Patents

Procedimiento para la obtencion de derivados de imidazol trisustituidos.

Info

Publication number
ES8306124A1
ES8306124A1 ES514584A ES514584A ES8306124A1 ES 8306124 A1 ES8306124 A1 ES 8306124A1 ES 514584 A ES514584 A ES 514584A ES 514584 A ES514584 A ES 514584A ES 8306124 A1 ES8306124 A1 ES 8306124A1
Authority
ES
Spain
Prior art keywords
carboxy
processes
compounds
imidazole derivatives
preparing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES514584A
Other languages
English (en)
Other versions
ES514584A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES514584A0 publication Critical patent/ES514584A0/es
Publication of ES8306124A1 publication Critical patent/ES8306124A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/53—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46—Oxygen atoms
    • C07D213/50—Ketonic radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D233/26—Radicals substituted by carbon atoms having three bonds to hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cosmetics (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE IMIDAZOL TRISUSTITUIDOS, DE FORMULA (I), EN LA QUE R Y R SON ARILO CARBOCICLICO O HETEROARILO; A ES UN RADICAL HIDROCARBONADO DIVALENTE; Y R PUEDE SER VARIOS RADICALES; ASI COMO DE SUS ISOMEROS Y SALES FISIOLOGICAMENTE COMPATIBLES. CONSISTE EN LA REACCION DE TRANSFORMACION POR OXIDACION DE UN RESTO R EN UN RESTO R EN UN COMPUESTO DE FORMULA (II), EN LA QUE R Y R TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I) Y R ES UN RESTO TRANSFORMABLE EN R . LA REACCION SE LLEVA A CABO MEDIANTE TRATAMIENTO CON COMPUESTOS DE PLATA O DE CROMO, CON PERMANGANATO O FERRATO POTASICO, EN UN DISOLVENTE INERTE A TEMPERATURAS ENTRE 0 C Y 150 C. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SU EFECTO ANTIINFLAMATORIO.
ES514584A 1980-07-25 1982-07-30 Procedimiento para la obtencion de derivados de imidazol trisustituidos. Expired ES8306124A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH571580 1980-07-25

Publications (2)

Publication Number Publication Date
ES514584A0 ES514584A0 (es) 1983-05-16
ES8306124A1 true ES8306124A1 (es) 1983-05-16

Family

ID=4298165

Family Applications (8)

Application Number Title Priority Date Filing Date
ES504257A Expired ES8301472A1 (es) 1980-07-25 1981-07-24 Procedimiento para la obtencion de derivados de imidazol trisustituidos
ES514584A Expired ES8306124A1 (es) 1980-07-25 1982-07-30 Procedimiento para la obtencion de derivados de imidazol trisustituidos.
ES514581A Expired ES8306121A1 (es) 1980-07-25 1982-07-30 Procedimiento para la obtencion de derivados de imidazol trisustituidos.
ES514582A Expired ES8306122A1 (es) 1980-07-25 1982-07-30 Procedimiento para la obtencion de derivados de imidazol trisustituidos.
ES514583A Expired ES8306123A1 (es) 1980-07-25 1982-07-30 Procedimiento para la obtencion de derivados de imidazol trisustituidos.
ES514585A Granted ES514585A0 (es) 1980-07-25 1982-07-30 Procedimiento para la obtencion de derivados de oxazol trisustituidos.
ES514580A Expired ES8306120A1 (es) 1980-07-25 1982-07-30 Procedimiento para la obtencion de derivados de imidazol trisustituidos.
ES514579A Expired ES8306119A1 (es) 1980-07-25 1982-07-30 Procedimiento para la obtencion de derivados de imidazol trisustituidos.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES504257A Expired ES8301472A1 (es) 1980-07-25 1981-07-24 Procedimiento para la obtencion de derivados de imidazol trisustituidos

Family Applications After (6)

Application Number Title Priority Date Filing Date
ES514581A Expired ES8306121A1 (es) 1980-07-25 1982-07-30 Procedimiento para la obtencion de derivados de imidazol trisustituidos.
ES514582A Expired ES8306122A1 (es) 1980-07-25 1982-07-30 Procedimiento para la obtencion de derivados de imidazol trisustituidos.
ES514583A Expired ES8306123A1 (es) 1980-07-25 1982-07-30 Procedimiento para la obtencion de derivados de imidazol trisustituidos.
ES514585A Granted ES514585A0 (es) 1980-07-25 1982-07-30 Procedimiento para la obtencion de derivados de oxazol trisustituidos.
ES514580A Expired ES8306120A1 (es) 1980-07-25 1982-07-30 Procedimiento para la obtencion de derivados de imidazol trisustituidos.
ES514579A Expired ES8306119A1 (es) 1980-07-25 1982-07-30 Procedimiento para la obtencion de derivados de imidazol trisustituidos.

Country Status (23)

Country Link
US (1) US4447431A (es)
EP (1) EP0045081B1 (es)
JP (1) JPS5756466A (es)
KR (13) KR850000883B1 (es)
AR (1) AR230269A1 (es)
AT (1) ATE17349T1 (es)
AU (2) AU7340481A (es)
CA (1) CA1175431A (es)
DD (2) DD201677A5 (es)
DE (1) DE3173434D1 (es)
DK (1) DK331881A (es)
ES (8) ES8301472A1 (es)
FI (1) FI812326L (es)
GB (1) GB2080805B (es)
GR (1) GR75287B (es)
IE (1) IE52071B1 (es)
IL (1) IL63410A (es)
NO (1) NO812542L (es)
NZ (1) NZ197828A (es)
PL (8) PL237002A1 (es)
PT (1) PT73424B (es)
SU (8) SU1235454A3 (es)
ZA (1) ZA815078B (es)

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GB2123831B (en) * 1981-07-20 1986-01-15 Ciba Geigy Ag Trisubstituted oxazo compounds
EP0084756A1 (de) * 1982-01-22 1983-08-03 Ciba-Geigy Ag Trisubstituierte Oxazaverbindungen
FR2633291B1 (fr) * 1988-06-27 1990-09-07 Oreal Derives d'hydroxy-4 isoxazoles, leur procede de preparation et compositions cosmetiques et pharmaceutiques les contenant
US5252322A (en) * 1989-09-22 1993-10-12 The Gillette Company Skin tanning compositions containing imidazoles
NZ239161A (en) * 1990-07-31 1994-01-26 Smithkline Beecham Corp Substituted [1h-imidazol-5-yl] alkanoic acid derivatives; medicaments,
IL104369A0 (en) * 1992-01-13 1993-05-13 Smithkline Beecham Corp Novel compounds and compositions
US5916891A (en) 1992-01-13 1999-06-29 Smithkline Beecham Corporation Pyrimidinyl imidazoles
US5593992A (en) * 1993-07-16 1997-01-14 Smithkline Beecham Corporation Compounds
US5670527A (en) * 1993-07-16 1997-09-23 Smithkline Beecham Corporation Pyridyl imidazole compounds and compositions
US5593991A (en) * 1993-07-16 1997-01-14 Adams; Jerry L. Imidazole compounds, use and process of making
WO1995013067A1 (en) 1993-11-08 1995-05-18 Smithkline Beecham Corporation Oxazoles for treating cytokine mediated diseases
US5723477A (en) * 1994-11-10 1998-03-03 Sibia Neurosciences, Inc. Modulators of acetylcholine receptors
US5658903A (en) * 1995-06-07 1997-08-19 Smithkline Beecham Corporation Imidazole compounds, compositions and use
US5739143A (en) * 1995-06-07 1998-04-14 Smithkline Beecham Corporation Imidazole compounds and compositions
US6369068B1 (en) 1995-06-07 2002-04-09 Smithkline Beecham Corporation Amino substituted pyrimidine containing compounds
ZA9610687B (en) * 1995-12-22 1997-09-29 Smithkline Beecham Corp Novel synthesis.
CZ216498A3 (cs) * 1996-01-11 1999-08-11 Smithkline Beecham Corporation Nové substituované imidazolové sloučeniny
AP9700912A0 (en) 1996-01-11 1997-01-31 Smithkline Beecham Corp Novel cycloalkyl substituted imidazoles
ZA97175B (en) * 1996-01-11 1997-11-04 Smithkline Beecham Corp Novel substituted imidazole compounds.
US6046208A (en) * 1996-01-11 2000-04-04 Smithkline Beecham Corporation Substituted imidazole compounds
JP2000507558A (ja) * 1996-03-25 2000-06-20 スミスクライン・ビーチャム・コーポレイション Ｃｎｓ損傷についての新規な治療
EP0956018A4 (en) 1996-08-21 2000-01-12 Smithkline Beecham Corp IMIDAZOLE COMPOUNDS, COMPOSITIONS CONTAINING THEM AND THEIR USE
US5929076A (en) * 1997-01-10 1999-07-27 Smithkline Beecham Corporation Cycloalkyl substituted imidazoles
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AR016294A1 (es) * 1997-07-02 2001-07-04 Smithkline Beecham Corp Compuesto de imidazol sustituido, composicion farmaceutica que la contiene, su uso en la fabricacion de un medicamento y procedimiento para supreparacion
US6562832B1 (en) 1997-07-02 2003-05-13 Smithkline Beecham Corporation Substituted imidazole compounds
EP1019396A1 (en) 1997-07-02 2000-07-19 SmithKline Beecham Corporation Novel cycloalkyl substituted imidazoles
TW517055B (en) 1997-07-02 2003-01-11 Smithkline Beecham Corp Novel substituted imidazole compounds
US7301021B2 (en) * 1997-07-02 2007-11-27 Smithkline Beecham Corporation Substituted imidazole compounds
US6489325B1 (en) 1998-07-01 2002-12-03 Smithkline Beecham Corporation Substituted imidazole compounds
US6362193B1 (en) 1997-10-08 2002-03-26 Smithkline Beecham Corporation Cycloalkenyl substituted compounds
US6335340B1 (en) 1997-12-19 2002-01-01 Smithkline Beecham Corporation compounds of heteroaryl substituted imidazole, their pharmaceutical compositons and uses
KR20010025087A (ko) 1998-05-22 2001-03-26 스튜어트 알. 수터 신규한 2-알킬 치환된 이미다졸 화합물
US6858617B2 (en) 1998-05-26 2005-02-22 Smithkline Beecham Corporation Substituted imidazole compounds
EP1112070B1 (en) * 1998-08-20 2004-05-12 Smithkline Beecham Corporation Novel substituted triazole compounds
AU1909200A (en) 1998-11-04 2000-05-22 Smithkline Beecham Corporation Pyridin-4-yl or pyrimidin-4-yl substituted pyrazines
WO2000029399A1 (en) * 1998-11-12 2000-05-25 Boehringer Ingelheim (Canada) Ltd. Antiherpes compounds
US6239279B1 (en) 1998-12-16 2001-05-29 Smithkline Beecham Corporation Synthesis for 4-aryl-5-pyrimidine imidazole substituted derivatives
DE60015594T2 (de) 1999-11-22 2005-10-27 Smithkline Beecham P.L.C., Brentford Imidazolderivate und deren verwendung als raf kinase inhibitoren
DE60023025T2 (de) 1999-11-23 2006-07-13 Smithkline Beecham Corp. 3,4-dihydro-(1h)chinazolin-2-on-verbindungen als csbp/p39-kinase-inhibitoren
EP1233951B1 (en) 1999-11-23 2005-06-01 SmithKline Beecham Corporation 3,4-dihydro-(1h)quinazolin-2-one compounds as csbp/p38 kinase inhibitors
US6759410B1 (en) * 1999-11-23 2004-07-06 Smithline Beecham Corporation 3,4-dihydro-(1H)-quinazolin-2-ones and their use as CSBP/p38 kinase inhibitors
ATE281439T1 (de) 1999-11-23 2004-11-15 Smithkline Beecham Corp 3,4-dihydro-(1h)chinazolin-2-on-verbindungen als csbp/p38-kinase-inhibitoren
US7235551B2 (en) * 2000-03-02 2007-06-26 Smithkline Beecham Corporation 1,5-disubstituted-3,4-dihydro-1h-pyrimido[4,5-d]pyrimidin-2-one compounds and their use in treating csbp/p38 kinase mediated diseases
JP2003525936A (ja) * 2000-03-06 2003-09-02 スミスクライン ビーチャム パブリック リミテッド カンパニー Ｒａｆキナーゼ阻害物質としてのイミダゾール誘導体
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US20040192689A1 (en) * 2001-09-05 2004-09-30 Dean David Kenneth Heterocycle-carboxamide derivatives as raf kinase inhibitors
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AU2006229995A1 (en) * 2005-03-25 2006-10-05 Glaxo Group Limited Process for preparing pyrido(2,3-d)pyrimidin-7-one and 3,4-dihydropyrimido(4,5-d)pyrimidin-2(1H)-one derivatives
MY145343A (en) 2005-03-25 2012-01-31 Glaxo Group Ltd Novel compounds
WO2013049272A2 (en) 2011-09-29 2013-04-04 Theraceutix, Llc Composition and method for treatment of symptoms associated with various skin conditions

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US3558645A (en) * 1968-07-08 1971-01-26 Sandoz Ag 2-(4-(4',5-diphenyl - 2 - imidazolyl)-phenoxy) lower aliphatic monocarboxylic acids
CH561718A5 (es) * 1971-05-10 1975-05-15 Ciba Geigy Ag
GB1469532A (en) * 1973-06-28 1977-04-06 Dumex Ltd As Imimdazolyl-alkanoic acid derivatives
US4372964A (en) * 1980-10-30 1983-02-08 E. I. Du Pont De Nemours And Company Antiinflammatory 4,5-diaryl-1H-imidazole-2-methanols

Also Published As

Publication number Publication date
JPS5756466A (en) 1982-04-05
KR850002756A (ko) 1985-05-15
ES514579A0 (es) 1983-05-16
SU1205763A3 (ru) 1986-01-15
CA1175431A (en) 1984-10-02
SU1152520A3 (en) 1985-04-23
FI812326L (fi) 1982-01-26
ES514583A0 (es) 1983-05-16
KR850000890B1 (ko) 1985-06-26
KR830006230A (ko) 1983-09-20
KR850000887B1 (ko) 1985-06-26
GB2080805A (en) 1982-02-10
ES8306123A1 (es) 1983-05-16
PL237003A1 (en) 1983-02-28
ES514582A0 (es) 1983-05-16
EP0045081B1 (de) 1986-01-08
KR850002752A (ko) 1985-05-15
NZ197828A (en) 1985-11-08
GB2080805B (en) 1984-03-07
ES514580A0 (es) 1983-05-16
SU1227112A3 (ru) 1986-04-23
ES504257A0 (es) 1982-12-01
IL63410A0 (en) 1981-10-30
KR850000889B1 (ko) 1985-06-26
IL63410A (en) 1986-04-29
PL232352A1 (es) 1982-12-20
IE52071B1 (en) 1987-06-10
ES8307245A1 (es) 1983-07-01
KR850002745A (ko) 1985-05-15
SU1205764A3 (ru) 1986-01-15
EP0045081A2 (de) 1982-02-03
SU1138023A3 (ru) 1985-01-30
GR75287B (es) 1984-07-13
AR230269A1 (es) 1984-03-01
KR850002755A (ko) 1985-05-15
US4447431A (en) 1984-05-08
KR850001064B1 (ko) 1985-07-25
DK331881A (da) 1982-01-26
PL237005A1 (en) 1983-02-28
ZA815078B (en) 1982-07-28
KR850000884B1 (ko) 1985-06-26
PL237001A1 (en) 1983-02-28
ATE17349T1 (de) 1986-01-15
PL236997A1 (en) 1983-01-03
AU7340481A (en) 1982-01-28
ES514584A0 (es) 1983-05-16
IE811680L (en) 1982-01-25
KR850002747A (ko) 1985-05-15
ES514585A0 (es) 1983-07-01
KR850000911B1 (ko) 1985-06-27
PT73424A (en) 1981-08-01
PL237004A1 (en) 1983-02-28
KR850000883B1 (ko) 1985-06-26
KR850002750A (ko) 1985-05-15
KR850002748A (ko) 1985-05-15
DD201677A5 (de) 1983-08-03
ES514581A0 (es) 1983-05-16
KR850000873B1 (ko) 1985-06-22
PT73424B (en) 1983-06-20
ES8306120A1 (es) 1983-05-16
KR850002753A (ko) 1985-05-15
EP0045081A3 (en) 1982-04-07
KR850000891B1 (ko) 1985-06-26
ES8306121A1 (es) 1983-05-16
ES8306122A1 (es) 1983-05-16
KR850002749A (ko) 1985-05-15
ES8306119A1 (es) 1983-05-16
DE3173434D1 (en) 1986-02-20
KR850000885B1 (ko) 1985-06-26
DD202554A5 (de) 1983-09-21
KR850002744A (ko) 1985-05-15
KR850000886B1 (ko) 1985-06-26
SU1169534A3 (ru) 1985-07-23
KR850002754A (ko) 1985-05-15
KR850000892B1 (ko) 1985-06-26
SU1145928A3 (ru) 1985-03-15
AU5655586A (en) 1986-09-11
KR850000888B1 (ko) 1985-06-26
PL237000A1 (en) 1983-02-28
ES8301472A1 (es) 1982-12-01
SU1235454A3 (ru) 1986-05-30
KR850002746A (ko) 1985-05-15
NO812542L (no) 1982-01-26
PL135822B1 (en) 1985-12-31
PL237002A1 (en) 1983-02-28

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