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ES552411A0 - Procedimiento para preparar nuevas pirrolidinonas substituidas - Google Patents

Procedimiento para preparar nuevas pirrolidinonas substituidas

Info

Publication number
ES552411A0
ES552411A0 ES552411A ES552411A ES552411A0 ES 552411 A0 ES552411 A0 ES 552411A0 ES 552411 A ES552411 A ES 552411A ES 552411 A ES552411 A ES 552411A ES 552411 A0 ES552411 A0 ES 552411A0
Authority
ES
Spain
Prior art keywords
group
carbon atoms
alkyl group
substituted
chained
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES552411A
Other languages
English (en)
Other versions
ES8707928A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim GmbH
Original Assignee
Boehringer Ingelheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim GmbH filed Critical Boehringer Ingelheim GmbH
Publication of ES8707928A1 publication Critical patent/ES8707928A1/es
Publication of ES552411A0 publication Critical patent/ES552411A0/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • C07D207/262-Pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D451/00Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ES552411A 1984-05-30 1986-02-26 Procedimiento para preparar nuevas pirrolidinonas substituidas Expired ES8707928A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843420193 DE3420193A1 (de) 1984-05-30 1984-05-30 Neue substituierte pyrrolidinone, verfahren zu ihrer herstellung und arzneimittel

Publications (2)

Publication Number Publication Date
ES8707928A1 ES8707928A1 (es) 1987-09-01
ES552411A0 true ES552411A0 (es) 1987-09-01

Family

ID=6237240

Family Applications (4)

Application Number Title Priority Date Filing Date
ES543592A Expired ES8607926A1 (es) 1984-05-30 1985-05-29 Procedimiento para preparar nuevas pirrolidinonas substitui-das
ES552410A Expired ES8707927A1 (es) 1984-05-30 1986-02-26 Procedimiento para preparar nuevas pirrolidinonas substituidas
ES552409A Expired ES8801200A1 (es) 1984-05-30 1986-02-26 Procedimiento para preparar nuevas pirrolidinonas substituidas
ES552411A Expired ES8707928A1 (es) 1984-05-30 1986-02-26 Procedimiento para preparar nuevas pirrolidinonas substituidas

Family Applications Before (3)

Application Number Title Priority Date Filing Date
ES543592A Expired ES8607926A1 (es) 1984-05-30 1985-05-29 Procedimiento para preparar nuevas pirrolidinonas substitui-das
ES552410A Expired ES8707927A1 (es) 1984-05-30 1986-02-26 Procedimiento para preparar nuevas pirrolidinonas substituidas
ES552409A Expired ES8801200A1 (es) 1984-05-30 1986-02-26 Procedimiento para preparar nuevas pirrolidinonas substituidas

Country Status (22)

Country Link
US (4) US4670456A (es)
EP (1) EP0163260B1 (es)
JP (1) JPS6168A (es)
KR (1) KR850008343A (es)
AT (1) ATE36151T1 (es)
AU (1) AU581438B2 (es)
CA (1) CA1255664A (es)
CS (1) CS261883B2 (es)
DD (1) DD235256A5 (es)
DE (2) DE3420193A1 (es)
DK (1) DK239685A (es)
ES (4) ES8607926A1 (es)
FI (1) FI78462C (es)
GR (1) GR851306B (es)
HU (1) HU193393B (es)
IL (1) IL75339A (es)
NO (1) NO852133L (es)
NZ (1) NZ212241A (es)
PL (1) PL144921B1 (es)
PT (1) PT80545B (es)
SU (1) SU1360583A3 (es)
ZA (1) ZA854072B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3336024A1 (de) * 1983-10-04 1985-04-18 Boehringer Ingelheim KG, 6507 Ingelheim 4-amino-l-benzyl-pyrrolidinone und ihre saeureadditionssalze, verfahren zu ihrer herstellung und arzneimittel
FR2597100A1 (fr) * 1986-01-21 1987-10-16 Nippon Shinyaku Co Ltd Derives du pyroglutamide
US4960776A (en) * 1987-01-28 1990-10-02 A. H. Robins Company, Inc. 4-aryl-N-(alkylaminoalkyl, heterocyclicamino and heterocyclicamino)alkyl)-1-piperazinecarboxamides
CA1305148C (en) * 1987-08-19 1992-07-14 Hiromu Matsumura Carbamoylpyrrolidone derivatives and drugs for senile dementia
US4833139A (en) * 1988-01-25 1989-05-23 Hoechst-Roussel Pharmaceuticals, Inc. Enhancing cholinergic activity with 5-substituted 1-[4-(1-pyrrolidinyl)-2-butynyl]-2-pyrrolidinones and related compounds
DE68903425T2 (de) * 1988-05-20 1993-03-25 Zambon Spa Verbindungen mit zentraler analgetischer verwendung, verfahren zu ihrer herstellung und arzneimittel die sie enthalten.
JPH02137427A (ja) * 1988-11-18 1990-05-25 Du Pont Opt Electron Kk 光電気的接続装置及び光コンセント
US4981974A (en) * 1989-05-08 1991-01-01 Gaf Chemicals Corporation Polymerizable pyrrolidonyl oxazoline monomers
JP5424480B2 (ja) * 2006-03-13 2014-02-26 杏林製薬株式会社 Gsk−3インヒビターとしてのアミノキノロン
KR101563018B1 (ko) * 2007-09-11 2015-10-23 교린 세이야꾸 가부시키 가이샤 Gsk-3 억제제로서의 시아노아미노퀴놀론 및 테트라졸로아미노퀴놀론
KR20100093104A (ko) * 2007-12-05 2010-08-24 아스트라제네카 아베 항비만제로서의 피페라진
MX2010006215A (es) 2007-12-05 2010-08-17 Astrazeneca Ab Derivados de piperazina y su uso como moduladores del receptor de leptina.
JP2011522009A (ja) * 2008-06-04 2011-07-28 アストラゼネカ アクチボラグ 新規化合物vii
WO2010104205A1 (en) * 2009-03-11 2010-09-16 Kyorin Pharmaceutical Co., Ltd. 7-cycloalkylaminoquinolones as gsk-3 inhibitors

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2838914A (en) * 1957-07-03 1958-06-17 Olin Mathieson Isonicotinic acid hydrazide derivatives
GB1039113A (en) * 1964-08-06 1966-08-17 Ucb Sa New n-substituted lactams
GB1309692A (en) * 1970-02-13 1973-03-14 Ucb Sa N-substituted lactams
JPS4924916B1 (es) * 1970-08-14 1974-06-26
FR2387218A1 (fr) * 1977-04-15 1978-11-10 Ile De France Nouveaux n-(1'-ethyl 2'-oxo 5'-pyrrolidinyl methyl) benzamides, leurs procedes de preparation et leur application comme modificateurs du comportement
CU21107A3 (es) * 1978-02-10 1988-02-01 Hoffmann La Roche Pyrrolidines derivatives
DE3326724A1 (de) * 1983-07-25 1985-02-07 Boehringer Ingelheim KG, 6507 Ingelheim In 1-stellung substituierte 4-hydroxymethyl-pyrrolidinone, verfahren zu ihrer herstellung, pharmazeutische zusammensetzungen und zwischenprodukte
DE3336024A1 (de) * 1983-10-04 1985-04-18 Boehringer Ingelheim KG, 6507 Ingelheim 4-amino-l-benzyl-pyrrolidinone und ihre saeureadditionssalze, verfahren zu ihrer herstellung und arzneimittel
GB8412358D0 (en) * 1984-05-15 1984-06-20 Ucb Sa Pharmaceutical composition
US4670436A (en) * 1986-08-29 1987-06-02 Mcneilab, Inc. Hypoglycemic 5-substituted pyrrolidinylidene compounds, compositions and use

Also Published As

Publication number Publication date
DE3564105D1 (en) 1988-09-08
FI78462B (fi) 1989-04-28
CS385485A2 (en) 1988-06-15
PL144921B1 (en) 1988-07-30
SU1360583A3 (ru) 1987-12-15
IL75339A0 (en) 1985-09-29
ES8607926A1 (es) 1986-06-01
ES8801200A1 (es) 1987-12-16
DK239685D0 (da) 1985-05-29
PT80545A (de) 1985-06-01
FI78462C (fi) 1989-08-10
CA1255664A (en) 1989-06-13
FI852130L (fi) 1985-12-01
US4891378A (en) 1990-01-02
EP0163260B1 (de) 1988-08-03
PL253668A1 (en) 1986-05-20
AU581438B2 (en) 1989-02-23
ES552409A0 (es) 1987-12-16
US4857528A (en) 1989-08-15
DK239685A (da) 1985-12-01
GR851306B (es) 1985-11-25
US4670456A (en) 1987-06-02
ES8707928A1 (es) 1987-09-01
HU193393B (en) 1987-09-28
CS261883B2 (en) 1989-02-10
DE3420193A1 (de) 1985-12-05
US4762832A (en) 1988-08-09
DD235256A5 (de) 1986-04-30
NO852133L (no) 1985-12-02
JPH0517904B2 (es) 1993-03-10
JPS6168A (ja) 1986-01-06
NZ212241A (en) 1989-07-27
ES8707927A1 (es) 1987-09-01
AU4317085A (en) 1985-12-05
EP0163260A1 (de) 1985-12-04
KR850008343A (ko) 1985-12-16
ATE36151T1 (de) 1988-08-15
FI852130A0 (fi) 1985-05-29
PT80545B (de) 1987-04-06
ZA854072B (en) 1987-02-25
HUT37751A (en) 1986-02-28
IL75339A (en) 1988-07-31
ES552410A0 (es) 1987-09-01
ES543592A0 (es) 1986-06-01

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