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ES524680A0 - Procedimiento de obtencion de nuevos compuestos derivados de la difenil-metilen-etilamina. - Google Patents

Procedimiento de obtencion de nuevos compuestos derivados de la difenil-metilen-etilamina.

Info

Publication number
ES524680A0
ES524680A0 ES524680A ES524680A ES524680A0 ES 524680 A0 ES524680 A0 ES 524680A0 ES 524680 A ES524680 A ES 524680A ES 524680 A ES524680 A ES 524680A ES 524680 A0 ES524680 A0 ES 524680A0
Authority
ES
Spain
Prior art keywords
ethylamine
diphenyl
methylene
new compounds
compounds derived
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES524680A
Other languages
English (en)
Other versions
ES8502099A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sociedad Espanola de Especialidades Farmaco Terapeuticas SA
Original Assignee
Sociedad Espanola de Especialidades Farmaco Terapeuticas SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sociedad Espanola de Especialidades Farmaco Terapeuticas SA filed Critical Sociedad Espanola de Especialidades Farmaco Terapeuticas SA
Priority to ES524680A priority Critical patent/ES524680A0/es
Priority to NZ208691A priority patent/NZ208691A/xx
Priority to NZ227317A priority patent/NZ227317A/xx
Priority to DE8484108424T priority patent/DE3483798D1/de
Priority to EP84108424A priority patent/EP0132764B1/en
Priority to AT84108424T priority patent/ATE59632T1/de
Priority to EP89114293A priority patent/EP0357956A3/en
Priority to AU31316/84A priority patent/AU580963B2/en
Priority to KR1019840004560A priority patent/KR900007198B1/ko
Priority to CA000460173A priority patent/CA1243018A/en
Priority to ZA845940A priority patent/ZA845940B/xx
Priority to JP59163743A priority patent/JPH0625091B2/ja
Publication of ES8502099A1 publication Critical patent/ES8502099A1/es
Publication of ES524680A0 publication Critical patent/ES524680A0/es
Priority to US07/054,408 priority patent/US4835156A/en
Priority to US07/054,409 priority patent/US4835179A/en
Priority to US07/336,881 priority patent/US5112826A/en
Granted legal-status Critical Current

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    • C07ORGANIC CHEMISTRY
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    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/335Radicals substituted by nitrogen atoms not forming part of a nitro radical
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C07D211/26Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
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    • C07D295/027Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
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    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/073Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
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    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
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    • C07D295/14Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
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    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/58Radicals substituted by nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms

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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Pharmacology & Pharmacy (AREA)
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  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Furan Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
ES524680A 1983-08-02 1983-08-02 Procedimiento de obtencion de nuevos compuestos derivados de la difenil-metilen-etilamina. Granted ES524680A0 (es)

Priority Applications (15)

Application Number Priority Date Filing Date Title
ES524680A ES524680A0 (es) 1983-08-02 1983-08-02 Procedimiento de obtencion de nuevos compuestos derivados de la difenil-metilen-etilamina.
NZ208691A NZ208691A (en) 1983-08-02 1984-06-28 Dihydrodibenzocycloheptylidene-ethylpiperazine derivatives and pharmaceutical compositions thereof
NZ227317A NZ227317A (en) 1983-08-02 1984-06-28 Dihydrodibenzocycloheptylidene-ethylamine derivatives and pharmaceutical compositions
DE8484108424T DE3483798D1 (de) 1983-08-02 1984-07-17 Dihydrodibenzocycloheptylidenethylamin-derivate.
EP84108424A EP0132764B1 (en) 1983-08-02 1984-07-17 Derivatives of dihydrodibenzocycloheptylidene-ethylamine
AT84108424T ATE59632T1 (de) 1983-08-02 1984-07-17 Dihydrodibenzocycloheptylidenethylamin-derivate
EP89114293A EP0357956A3 (en) 1983-08-02 1984-07-17 Vasodilatory dihydrobenzocycloheptiliden-ethyl-piperazine derivatives and process for preparation thereof
AU31316/84A AU580963B2 (en) 1983-08-02 1984-07-30 New compounds derived from diphenyl-methylene-ethylamine
KR1019840004560A KR900007198B1 (ko) 1983-08-02 1984-07-31 디페닐-메틸렌-에틸아민 유도체의 제조방법
CA000460173A CA1243018A (en) 1983-08-02 1984-08-01 Compounds derived from diphenyl-methylene-ethilamine, their method of preparation, the pharmaceutical compositions containing them and their use in human medicine
ZA845940A ZA845940B (en) 1983-08-02 1984-08-01 New compounds derived from diphenyl-methylene-ethylamine
JP59163743A JPH0625091B2 (ja) 1983-08-02 1984-08-02 ジヒドロジベンゾシクロヘプチリデン―エチルアミン誘導体その製法ならびに医薬組成物
US07/054,408 US4835156A (en) 1983-08-02 1987-05-26 Vasodilatory dihydrodibenzocycloheptyliden-ethyl piperazine derivatives and process for the preparation of these compounds
US07/054,409 US4835179A (en) 1983-08-02 1987-05-26 Antiulcer dihydrodibenzocycloheptyliden-ethylamine derivatives and process for the preparation of these compounds
US07/336,881 US5112826A (en) 1983-08-02 1989-04-12 Vasodilatory dihydrodibenzocycloheptyliden-ethylpiperazine derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES524680A ES524680A0 (es) 1983-08-02 1983-08-02 Procedimiento de obtencion de nuevos compuestos derivados de la difenil-metilen-etilamina.

Publications (2)

Publication Number Publication Date
ES8502099A1 ES8502099A1 (es) 1984-12-16
ES524680A0 true ES524680A0 (es) 1984-12-16

Family

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Application Number Title Priority Date Filing Date
ES524680A Granted ES524680A0 (es) 1983-08-02 1983-08-02 Procedimiento de obtencion de nuevos compuestos derivados de la difenil-metilen-etilamina.

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Country Link
US (3) US4835156A (es)
EP (2) EP0357956A3 (es)
JP (1) JPH0625091B2 (es)
KR (1) KR900007198B1 (es)
AT (1) ATE59632T1 (es)
AU (1) AU580963B2 (es)
CA (1) CA1243018A (es)
DE (1) DE3483798D1 (es)
ES (1) ES524680A0 (es)
NZ (1) NZ208691A (es)
ZA (1) ZA845940B (es)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES524680A0 (es) * 1983-08-02 1984-12-16 Espanola Farma Therapeut Procedimiento de obtencion de nuevos compuestos derivados de la difenil-metilen-etilamina.
US4882351A (en) * 1987-10-14 1989-11-21 Roussel Uclaf Tricyclic compounds
IT1222986B (it) * 1987-10-23 1990-09-12 Texcontor Ets Derivati dell'efedrina esterificata aventi attivita' antiulcera prolungata nel tempo
DE69127549T2 (de) * 1990-05-18 1998-04-23 Merrell Pharma Inc 5h-dibenzo[a,d]cycloheptene als muscarinic-rezeptor-antagonist
US5508280A (en) * 1990-05-18 1996-04-16 Merrell Pharmaceuticals, Inc. 5H-Dibenzo (A,D) cycloheptenes as muscarinic receptor antagonists
JP2574733Y2 (ja) * 1991-09-04 1998-06-18 松下電器産業株式会社 車両用ハーネス案内装置
ES2194217T3 (es) * 1996-10-04 2003-11-16 Novo Nordisk As Spperazinas 1,4-disustituidas.
US6613905B1 (en) * 1998-01-21 2003-09-02 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
US7541365B2 (en) 2001-11-21 2009-06-02 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
TWI291467B (en) 2002-11-13 2007-12-21 Millennium Pharm Inc CCR1 antagonists and methods of use therefor
WO2014108449A1 (en) 2013-01-08 2014-07-17 Atrogi Ab A screening method, a kit, a method of treatment and a compound for use in a method of treatment
GB201714736D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714745D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714740D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714734D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB202205895D0 (en) 2022-04-22 2022-06-08 Atrogi Ab New medical uses

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NL6507535A (es) * 1965-06-11 1966-12-12
NL130988C (es) * 1966-07-21 Boehringer Mannheim Gmbh
JPS5111622B2 (es) * 1972-08-31 1976-04-13
US3906110A (en) * 1973-02-07 1975-09-16 Ciba Geigy Corp Antihypertensive {60 -(1-aralkylaminoalkyl)-aralkoxybenzyl alcohols
JPS525504B2 (es) * 1973-02-21 1977-02-14
JPS5231336B2 (es) * 1974-05-23 1977-08-13
JPS52105155A (en) * 1976-03-02 1977-09-03 Hokuriku Pharmaceutical Diphenylarylaminoalkanol quarternary salt derivatives and process for preparing same
NO154582C (no) 1978-10-20 1986-11-05 Ferrosan Ab Analogifremgangsmaate for fremstilling av terapeutisk aktive difenyl-dibutylpiperazinkarboksamider.
US4308587A (en) * 1979-12-26 1981-12-29 Becton Dickinson And Company Apparatus for displaying at least two parameters of populations of particles on a cathode ray tube
IT1150959B (it) 1980-06-10 1986-12-17 Simes Sostanze datate di attivita' antispastica vasale e procedimenti per la loro preparazione
US4381505A (en) * 1980-12-10 1983-04-26 The Arthur G. Russell Company, Incorporated System for displaying alphanumerical messages having stored and real time components
CA1160219A (en) 1981-01-16 1984-01-10 Werner Aschwanden Cycloheptene derivatives
ES524680A0 (es) * 1983-08-02 1984-12-16 Espanola Farma Therapeut Procedimiento de obtencion de nuevos compuestos derivados de la difenil-metilen-etilamina.
AU612437B2 (en) * 1987-12-14 1991-07-11 Kyowa Hakko Kogyo Co. Ltd. Tricyclic compounds

Also Published As

Publication number Publication date
NZ208691A (en) 1989-06-28
DE3483798D1 (de) 1991-02-07
ZA845940B (en) 1986-08-27
US5112826A (en) 1992-05-12
EP0357956A2 (en) 1990-03-14
KR850002261A (ko) 1985-05-10
EP0132764A3 (en) 1985-12-04
EP0132764B1 (en) 1991-01-02
JPS60126265A (ja) 1985-07-05
AU3131684A (en) 1985-02-07
CA1243018A (en) 1988-10-11
EP0357956A3 (en) 1990-08-29
ES8502099A1 (es) 1984-12-16
US4835156A (en) 1989-05-30
US4835179A (en) 1989-05-30
AU580963B2 (en) 1989-02-09
JPH0625091B2 (ja) 1994-04-06
KR900007198B1 (ko) 1990-10-05
EP0132764A2 (en) 1985-02-13
ATE59632T1 (de) 1991-01-15

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