ES456404A1 - A procedure for the preparation of 4'-epi-6'hidroxiadricina. (Machine-translation by Google Translate, not legally binding)
- Google Patents
A procedure for the preparation of 4'-epi-6'hidroxiadricina. (Machine-translation by Google Translate, not legally binding)
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FARMACEUTIVI ITALIANA SpA SO
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FARMACEUTIVI ITALIANA SpA SO
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Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Saccharide Compounds
(AREA)
Abstract
Process for the preparation of new antitumor glycosides, 4 "-epi-6" -hydroxydaunomycin and 4 "-epi-6" -hydroxy-adriamycin. The novel compounds of the invention exhibit both "in vivo" and "in vitro" antimitotic activity and are useful therapeutic agents for the treatment of tumor and viral diseases in humans. More specifically, the invention provides a process that is used for the preparation of 4 "-epi-6" - hydrohydroxyunomicin (I) ** (formula) ** condensate daunomycinone (II) with 1, 2, 3-trideoxy -4,6-di-0- (p-nitrobenzoyl) -3-trifluoro-acetamido-l-arabino-hex-1-anepyranose. (Machine-translation by Google Translate, not legally binding)
ES456404A1976-10-291976-03-01A procedure for the preparation of 4'-epi-6'hidroxiadricina. (Machine-translation by Google Translate, not legally binding)
ExpiredES456404A1
(en)
N-(1-allyl-2-pyrrolidylmethyl)-2,3-dimethoxy-5-sulfamoylbenzamide and derivatives thereof and method for treating hot flushes associated with natural or surgical menopause