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ES2106785T3 - Medicamentos, su preparacion y empleo como analgesicos y/o antiinflamatorios para seres humanos y animales. - Google Patents

Medicamentos, su preparacion y empleo como analgesicos y/o antiinflamatorios para seres humanos y animales.

Info

Publication number
ES2106785T3
ES2106785T3 ES91914752T ES91914752T ES2106785T3 ES 2106785 T3 ES2106785 T3 ES 2106785T3 ES 91914752 T ES91914752 T ES 91914752T ES 91914752 T ES91914752 T ES 91914752T ES 2106785 T3 ES2106785 T3 ES 2106785T3
Authority
ES
Spain
Prior art keywords
inflammatories
analgesics
medications
humans
animals
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91914752T
Other languages
English (en)
Other versions
ES2106785T5 (es
Inventor
Gerd Geisslinger
Kay Brune
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PAZ ARZNEIMITTELENTWICKLUNG
Original Assignee
PAZ ARZNEIMITTELENTWICKLUNG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6414093&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2106785(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by PAZ ARZNEIMITTELENTWICKLUNG filed Critical PAZ ARZNEIMITTELENTWICKLUNG
Publication of ES2106785T3 publication Critical patent/ES2106785T3/es
Application granted granted Critical
Publication of ES2106785T5 publication Critical patent/ES2106785T5/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Empleo de Flurbiprofeno en la preparación de un medicamento para tratar afecciones dolorosas, caracterizado porque en caso de dolores o cuadros patológicos crónicos con estados de dolor dominantes se usa 60 hasta 99,5%, preferentemente 60 hasta 95% de R(-)-Flurbiprofeno, y el resto de S(+)-Flurbiprofeno, en que los enantiómeros del Flurbiprofeno, previamente separados, se recombinan en la relación deseada y se mezclan con los soportes sólidos y las materias auxiliares habituales en farmacia, para elaborar medicamentos.
ES91914752T 1990-09-12 1991-08-19 Medicamentos, su preparacion y empleo como analgesicos y/o antiinflamatorios para seres humanos y animales. Expired - Lifetime ES2106785T5 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4028906A DE4028906A1 (de) 1990-09-12 1990-09-12 Arzneimittel sowie deren herstellung und deren verwendung bei der bekaempfung von schmerzen und/oder entzuendungen und/oder fieber an tieren und menschen
DE4028906 1990-09-12

Publications (2)

Publication Number Publication Date
ES2106785T3 true ES2106785T3 (es) 1997-11-16
ES2106785T5 ES2106785T5 (es) 2007-10-16

Family

ID=6414093

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91914752T Expired - Lifetime ES2106785T5 (es) 1990-09-12 1991-08-19 Medicamentos, su preparacion y empleo como analgesicos y/o antiinflamatorios para seres humanos y animales.

Country Status (14)

Country Link
US (2) US5206029A (es)
EP (1) EP0607128B2 (es)
JP (1) JP3305315B2 (es)
AT (1) ATE158182T1 (es)
AU (1) AU654498B2 (es)
CA (1) CA2087723C (es)
DE (2) DE4028906A1 (es)
DK (1) DK0607128T4 (es)
ES (1) ES2106785T5 (es)
FI (1) FI103180B1 (es)
GR (1) GR3025502T3 (es)
HU (1) HU225887B1 (es)
RU (1) RU2080116C1 (es)
WO (1) WO1992004018A1 (es)

Families Citing this family (51)

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DE4140172C2 (de) * 1991-12-05 1995-12-21 Alfatec Pharma Gmbh Retardform für ein Ibuprofen enthaltendes Arzneimittel
DE4140185C2 (de) * 1991-12-05 1996-02-01 Alfatec Pharma Gmbh Ein 2-Arylpropionsäurederivat in Nanosolform enthaltendes Arzneimittel und seine Herstellung
DE4140183C2 (de) * 1991-12-05 1995-12-21 Alfatec Pharma Gmbh Retardform für ein Flurbiprofen enthaltendes Arzneimittel
DE4140184C2 (de) * 1991-12-05 1995-12-21 Alfatec Pharma Gmbh Akutform für ein Flurbiprofen enthaltendes Arzneimittel
DE4216756C2 (de) * 1992-05-21 1994-08-25 Pharmatrans Sanaq Ag 2-Arylpropionsäure-Zubereitungen und Verfahren zu ihrer Herstellung
RU2133733C1 (ru) * 1992-12-02 1999-07-27 Дзе бутс компани ПЛС. Способ получения фенилпропионовой кислоты
DE4319438C1 (de) * 1993-06-11 1994-06-01 Gerd Dr Dr Geislinger Arzneimittel auf der Grundlage von Ketoprofen zur Bekämpfung von Schmerzen und/oder Entzündungen und/oder Fieber an Menschen und Tieren
JP3782834B2 (ja) * 1994-10-26 2006-06-07 株式会社トクホン 鎮痛抗炎症貼付剤
IT1271800B (it) * 1994-12-27 1997-06-09 Zambon Spa Processo di preparazione degli enantiomeri dell'acido 2- (2-fluoro- 4-bifenil) propionico
US5981592A (en) * 1995-03-13 1999-11-09 Loma Linda University Medical Center Method and composition for treating cystic fibrosis
US6160018A (en) * 1995-03-13 2000-12-12 Loma Linda University Medical Center Prophylactic composition and method for alzheimer's Disease
US5955504A (en) * 1995-03-13 1999-09-21 Loma Linda University Medical Center Colorectal chemoprotective composition and method of preventing colorectal cancer
AT408067B (de) * 1995-03-17 2001-08-27 Gebro Pharma Gmbh Pharmazeutische zusammensetzung zur topischen applizierung und verfahren zu ihrer herstellung
GB9523833D0 (en) * 1995-11-22 1996-01-24 Boots Co Plc Medical treatment
US5702720A (en) * 1995-12-22 1997-12-30 Minnesota Mining And Manufacturing Company Transdermal device for the delivery of flurbiprofen
JP2001514655A (ja) * 1997-03-10 2001-09-11 ローマ リンダ ユニバーシティ メディカル センター アルツハイマー病予防へのｒ−ｎｓａｉｄ’ｓの利用
GB9705989D0 (en) * 1997-03-22 1997-05-07 Boots Co Plc Therapeutic composition
DE69933049T2 (de) 1998-09-03 2007-10-04 Loma Linda University Medical Center, Loma Linda Pharmazeutische zusammensetzung und verwendung von rnsaid zur behandlung der entzündung
AU2004222809B2 (en) * 1998-09-03 2007-06-28 Loma Linda University Medical Center Pharmaceutical Composition and Method for Treatment of Inflammation
DE19907895A1 (de) * 1999-02-24 2000-11-16 Paz Arzneimittelentwicklung Verwendung von R-Arylpropionsäuren zur Herstellung von Arzneimitteln zur Behandlung von Erkrankungen bei Mensch und Tier, welche durch die Hemmung der Aktivierung von NF-kB therapeutisch beeinflußt werden können
US20060004086A1 (en) * 2000-04-13 2006-01-05 Mayo Foundation For Medical Education And Research Method of reducing Abeta42 and treating diseases
AU5702201A (en) * 2000-04-13 2001-10-30 Mayo Foundation Abeta<sub>42</sub> lowering agents
US20080021085A1 (en) * 2000-04-13 2008-01-24 Mayo Foundation For Medical Education And Research Method of reducing abeta42 and treating diseases
DE10047319A1 (de) 2000-09-25 2002-04-18 Paz Arzneimittelentwicklung Verwendung von R-Arylpropionsäuren zur Herstellung von Arzneimitteln zur Behandlung von Erkrankungen, welche durch die Hemmung der Aktivierung des nukleären Transkriptionsfaktors AP-1 therapeutisch beeinflußt werden können
US6497901B1 (en) * 2000-11-02 2002-12-24 Royer Biomedical, Inc. Resorbable matrices for delivery of bioactive compounds
BR0209965A (pt) 2001-05-21 2004-04-06 Alcon Inc Uso de inibidores de nf-kappab para tratar distúrbios do olho seco
US20030027867A1 (en) * 2001-06-29 2003-02-06 Myriad Genetics, Incorporated Use of R-NSAID compounds for anti-HIV treatment
US20030143165A1 (en) * 2002-01-25 2003-07-31 Allan Evans NSAID-containing topical formulations that demonstrate chemopreventive activity
US7247328B2 (en) * 2002-05-31 2007-07-24 Zinpro Corporation Chromium (III) alpha amino acid complexes
US7129375B2 (en) * 2002-10-16 2006-10-31 Zinpro Corporation Metal complexes of α amino dicarboxylic acids
EP1603548A4 (en) * 2003-02-05 2007-10-10 Myriad Genetics Inc COMPOSITION AND METHOD FOR TREATING NEURODEGENERATIVE DISORDERS
US6953507B2 (en) * 2003-03-21 2005-10-11 Ecolab Inc. Low temperature cleaning
AU2004311577A1 (en) * 2003-07-11 2005-07-21 Myriad Genetics, Inc. Pharmaceutical methods, dosing regimes and dosage forms for the treatment of Alzheimer's disease
US20050171207A1 (en) * 2003-09-26 2005-08-04 Myriad Genetics, Incorporated Method and composition for combination treatment of neurodegenerative disorders
FR2865648B1 (fr) * 2004-02-03 2006-06-30 Philippe Perovitch Procede de diffusion de molecules insolubles en milieu aqueux et composition mettant en oeuvre ce procede
US20070293538A1 (en) * 2004-04-13 2007-12-20 Myriad Genetics, Incorporated Pharmaceutical Composition And Methods For Treating Neurodegenerative Disorders
MXPA06012165A (es) * 2004-04-29 2007-01-17 Keystone Retaining Wall System Chapas para muros, muros de contencion y similares.
WO2006020852A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
WO2006020850A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
CA2618985A1 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
BRPI0613611A2 (pt) * 2005-07-22 2011-01-18 Myriad Genetics Inc formulações de alta concentração de fármaco e formas de dosagens
US20070042094A1 (en) 2005-08-22 2007-02-22 Alcide Corporation Oxidation method and compositions therefor
WO2008006099A2 (en) * 2006-07-07 2008-01-10 Myriad Genetics, Inc. Treatment of psychiatric disorders
ES2373838T3 (es) * 2007-12-21 2012-02-09 Horizon Pharma Ag Medicamento así como su preparación y su utilización en el tratamiento de neuropatías dolorosas.
US20090162421A1 (en) * 2007-12-21 2009-06-25 Paz Arzneimittel-Entwicklungsgesellschaft Mbh Drugs as well as their production and use in the treatment of pain-associated neuropathies
RU2532027C2 (ru) 2009-07-24 2014-10-27 Мика Фарма Гезельшафт Фюр Ди Энтвиклюнг Унд Фермарктунг Фармацойтишер Продукте Мбх Жидкие композиции, способные к пенообразованию и включающие активные средства, и способы их получения и разработки
EP2468270A1 (en) 2010-12-21 2012-06-27 GALENpharma GmbH (R)-2-(3-fluoro-4-phenylphenyl)propionic acid for use in the treatment of skin diseases
WO2014015341A2 (en) * 2012-07-20 2014-01-23 Vanderbilt University Compositions and methods for substrate-selective inhibition of endocannabinoid oxygenation
US9578879B1 (en) 2014-02-07 2017-02-28 Gojo Industries, Inc. Compositions and methods having improved efficacy against spores and other organisms
CN113262216A (zh) * 2020-02-14 2021-08-17 北京泰德制药股份有限公司 一种用于消除皮表红肿镇痛的外用制剂
CN118125916A (zh) * 2022-09-23 2024-06-04 南京知和医药科技有限公司 一种s-（+）-氟比洛芬盐及其制备方法、药物组合物和用途

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US3784705A (en) * 1964-01-24 1974-01-08 Boots Pure Drug Co Ltd Therapeutically active phenylalkane derivatives
US4209638A (en) * 1977-03-08 1980-06-24 The Boots Company Limited Preparation of therapeutic agents
GR64816B (en) * 1977-03-08 1980-06-03 Boots Co Ltd Resolution of flurbiprofen ii/iii
ZA828453B (en) † 1981-12-08 1983-12-28 Boots Co Plc Therapeutic agents
JPS6283885A (ja) † 1985-10-08 1987-04-17 Nitto Electric Ind Co Ltd 酵素固定膜及びその製造方法
US4927854A (en) * 1987-12-24 1990-05-22 Analgesic Associates Sustained/enhanced analgesia
AU6758990A (en) † 1989-11-06 1991-05-31 Sepracor, Inc. Analgesic composition containing optically pure s(+) flurbiprofen

Also Published As

Publication number Publication date
JP3305315B2 (ja) 2002-07-22
FI103180B (fi) 1999-05-14
CA2087723C (en) 2002-07-23
US5206029A (en) 1993-04-27
FI931097A0 (fi) 1993-03-11
US5200198A (en) 1993-04-06
JPH06500313A (ja) 1994-01-13
WO1992004018A1 (de) 1992-03-19
ATE158182T1 (de) 1997-10-15
GR3025502T3 (en) 1998-02-27
CA2087723A1 (en) 1992-03-13
HUT63564A (en) 1993-09-28
EP0607128B2 (de) 2007-02-21
DK0607128T3 (da) 1998-04-14
DE4028906A1 (de) 1992-03-19
FI931097A (fi) 1993-03-11
EP0607128A1 (de) 1994-07-27
DK0607128T4 (da) 2007-05-07
HU9300636D0 (en) 1993-05-28
AU654498B2 (en) 1994-11-10
AU8335291A (en) 1992-03-30
EP0607128B1 (de) 1997-09-17
DE4028906C2 (es) 1992-10-29
DE59108854D1 (de) 1997-10-23
FI103180B1 (fi) 1999-05-14
HU225887B1 (en) 2007-11-28
RU2080116C1 (ru) 1997-05-27
ES2106785T5 (es) 2007-10-16

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