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ES2178203T3 - Metodos y reactivos para modular la apoptosis. - Google Patents

Metodos y reactivos para modular la apoptosis.

Info

Publication number
ES2178203T3
ES2178203T3 ES98917503T ES98917503T ES2178203T3 ES 2178203 T3 ES2178203 T3 ES 2178203T3 ES 98917503 T ES98917503 T ES 98917503T ES 98917503 T ES98917503 T ES 98917503T ES 2178203 T3 ES2178203 T3 ES 2178203T3
Authority
ES
Spain
Prior art keywords
bap31
methods
reagents
apoptosis
modulate apoptosis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES98917503T
Other languages
English (en)
Inventor
Gordon C Shore
W H Florence Ng
Mai Nguyen
Philip E Branton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
McGill University
Original Assignee
McGill University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by McGill University filed Critical McGill University
Application granted granted Critical
Publication of ES2178203T3 publication Critical patent/ES2178203T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4747Apoptosis related proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

LA INVENCION PROPORCIONA UNA NUEVA PROTEINA DE LA APOPTOSIS: P28 BAP31. SE PROPORCIONAN TAMBIEN FRAGMENTOS POLIPEPTIDICOS DE DICHA PROTEINA, MOLECULAS DEL ACIDO NUCLEICO ANTISENTIDO DE LA P28 BAP31, ANTICUERPOS DIRIGIDOS CONTRA LA MISMA, Y PROCEDIMIENTOS PARA MODULAR LA APOPTOSIS Y PARA DETECTAR COMPUESTOS QUE LA MODULAN.
ES98917503T 1997-03-03 1998-03-02 Metodos y reactivos para modular la apoptosis. Expired - Lifetime ES2178203T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA002198988A CA2198988A1 (en) 1997-03-03 1997-03-03 P28 bap31 a bcl-2 associated protein and use thereof for the modulation of apoptosis

Publications (1)

Publication Number Publication Date
ES2178203T3 true ES2178203T3 (es) 2002-12-16

Family

ID=4160084

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98917503T Expired - Lifetime ES2178203T3 (es) 1997-03-03 1998-03-02 Metodos y reactivos para modular la apoptosis.

Country Status (9)

Country Link
US (2) US6607880B1 (es)
EP (1) EP0900275B1 (es)
JP (1) JP2000511781A (es)
AT (1) ATE219515T1 (es)
AU (1) AU749896B2 (es)
CA (1) CA2198988A1 (es)
DE (1) DE69806107T2 (es)
ES (1) ES2178203T3 (es)
WO (1) WO1998039434A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000059924A1 (en) * 1999-04-06 2000-10-12 President And Fellows Of Harvard College Methods and reagents for modulating caspase-mediated apoptosis
WO2001089582A1 (fr) * 2000-05-26 2001-11-29 Takeda Chemical Industries, Ltd. Prophylactiques de l'hypertension pulmonaire et remèdes
WO2005089791A1 (en) * 2004-03-09 2005-09-29 Board Of Regents, The University Of Texas System Pea15 as a tumor suppressor gene
WO2008097854A2 (en) * 2007-02-02 2008-08-14 Loma Linda University Method and substances for treating hpv infection
CN101659703B (zh) * 2009-10-09 2012-12-05 天津医科大学附属肿瘤医院 抗人bap31蛋白的单克隆抗体及其制备方法和应用
JP6050289B2 (ja) * 2013-07-11 2016-12-21 Jcrファーマ株式会社 組換え蛋白質高発現細胞株の選択法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5283173A (en) * 1990-01-24 1994-02-01 The Research Foundation Of State University Of New York System to detect protein-protein interactions

Also Published As

Publication number Publication date
EP0900275A1 (en) 1999-03-10
US6558950B1 (en) 2003-05-06
JP2000511781A (ja) 2000-09-12
AU749896B2 (en) 2002-07-04
AU7071698A (en) 1998-09-22
DE69806107T2 (de) 2002-11-21
WO1998039434A1 (en) 1998-09-11
US6607880B1 (en) 2003-08-19
EP0900275B1 (en) 2002-06-19
CA2198988A1 (en) 1998-09-03
DE69806107D1 (de) 2002-07-25
ATE219515T1 (de) 2002-07-15

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