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ES2172023T3 - NEW SUBSTITUTED TETRAHYDRA-PYRIDINIC DERIVATIVES, THEIR PREPARATION PROCEDURE AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. - Google Patents

NEW SUBSTITUTED TETRAHYDRA-PYRIDINIC DERIVATIVES, THEIR PREPARATION PROCEDURE AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.

Info

Publication number
ES2172023T3
ES2172023T3 ES97948974T ES97948974T ES2172023T3 ES 2172023 T3 ES2172023 T3 ES 2172023T3 ES 97948974 T ES97948974 T ES 97948974T ES 97948974 T ES97948974 T ES 97948974T ES 2172023 T3 ES2172023 T3 ES 2172023T3
Authority
ES
Spain
Prior art keywords
tetrahydra
pharmaceutical compositions
compositions containing
preparation procedure
new substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97948974T
Other languages
Spanish (es)
Inventor
Christian Marazano
Delphine Compere
C Bhupesh Das
Jean Lepagnol
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoires Servier SAS
Original Assignee
Laboratoires Servier SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Servier SAS filed Critical Laboratoires Servier SAS
Application granted granted Critical
Publication of ES2172023T3 publication Critical patent/ES2172023T3/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

LA INVENCION SE REFIERE A LOS COMPUESTOS DE FORMULA GENERAL (I) EN LA QUE R, R 1 , R 2 , X E Y SON TALES COMO SE DEFINEN EN LA DESCRIPCION, SUS ISOMEROS GEOMETRICOS Y/O OPTICOS Y SUS SALES DE ADICION A UN ACIDO O UNA BASE FARMACEUTICAMENTE ACEPTABLES. APLICACION: MEDICAMENTOS.THE INVENTION REFERS TO THE COMPOUNDS OF GENERAL FORMULA (I) IN WHICH R, R 1, R 2, XEY ARE SUCH AS DEFINED IN THE DESCRIPTION, ITS GEOMETRIC AND / OR OPTICAL ISOMERS AND ITS ADDITION SALTS TO AN ACID OR A PHARMACEUTICALLY ACCEPTABLE BASE. APPLICATION: MEDICATIONS.

ES97948974T 1996-12-05 1997-12-02 NEW SUBSTITUTED TETRAHYDRA-PYRIDINIC DERIVATIVES, THEIR PREPARATION PROCEDURE AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. Expired - Lifetime ES2172023T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9614951A FR2756826B1 (en) 1996-12-05 1996-12-05 NOVEL SUBSTITUTED TETRAHYDROPYRIDINIC DERIVATIVES, THEIR PREPARATION PROCESS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Publications (1)

Publication Number Publication Date
ES2172023T3 true ES2172023T3 (en) 2002-09-16

Family

ID=9498371

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97948974T Expired - Lifetime ES2172023T3 (en) 1996-12-05 1997-12-02 NEW SUBSTITUTED TETRAHYDRA-PYRIDINIC DERIVATIVES, THEIR PREPARATION PROCEDURE AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.

Country Status (19)

Country Link
US (1) US6232319B1 (en)
EP (1) EP0937043B1 (en)
JP (1) JP3872821B2 (en)
CN (1) CN1126739C (en)
AT (1) ATE214051T1 (en)
AU (1) AU719208B2 (en)
CA (1) CA2274133C (en)
DE (1) DE69710909T2 (en)
DK (1) DK0937043T3 (en)
ES (1) ES2172023T3 (en)
FR (1) FR2756826B1 (en)
HK (1) HK1023346A1 (en)
HU (1) HUP0001773A3 (en)
NO (1) NO313589B1 (en)
NZ (1) NZ336111A (en)
PL (1) PL189372B1 (en)
PT (1) PT937043E (en)
WO (1) WO1998024765A1 (en)
ZA (1) ZA9710960B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2793245B1 (en) * 1999-05-05 2002-10-11 Adir NOVEL SUBSTITUTED PYRIDINIC OR PIPERIDINIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
DE10164139A1 (en) 2001-12-27 2003-07-10 Bayer Ag 2-heteroaryl carboxamides
US7238715B2 (en) * 2002-12-06 2007-07-03 The Feinstein Institute For Medical Research Treatment of pancreatitis using alpha 7 receptor-binding cholinergic agonists
ATE378048T1 (en) * 2002-12-06 2007-11-15 The Feinstein Inst Medical Res INHIBITION OF INFLAMMATION USING ALPHA-7 RECEPTOR-LINKING CHOLINERGIC AGONISTS
US8316104B2 (en) 2005-11-15 2012-11-20 California Institute Of Technology Method and apparatus for collaborative system
PE20110711A1 (en) 2008-11-19 2011-10-11 Envivo Pharmaceuticals Inc TREATMENT OF COGNITIVE DISORDERS WITH (R) -7-CHLORO-N- (QUINUCLIDIN-3-IL) BENZO [B] THIOPHENE-2-CARBOXAMIDE AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF
TW201031664A (en) 2009-01-26 2010-09-01 Targacept Inc Preparation and therapeutic applications of (2S,3R)-N-2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)-3,5-difluorobenzamide
PE20120324A1 (en) * 2009-05-11 2012-04-17 Envivo Pharmaceuticals Inc COMBINATION INCLUDING (R) -7-CHLORO-N- (QUINUCLIDIN-3-IL) BENZO [B] THIOPHENE-2-CARBOXAMIDE AND DONEZEPYL AS A MODULATOR OF COGNITIVE DISORDERS
HUE035608T2 (en) 2010-05-17 2018-05-28 Forum Pharmaceuticals Inc Pharmaceutical formulations comprising crystalline forms of (r)-7-chloro-n-(quinuclidin-3-yl)benzo(b)thiophene-2-carboxamide hydrochloride monohydrate
EP3461481A1 (en) 2012-05-08 2019-04-03 Forum Pharmaceuticals Inc. Methods of maintaining, treating or improving cognitive function

Also Published As

Publication number Publication date
US6232319B1 (en) 2001-05-15
DE69710909T2 (en) 2002-11-07
CA2274133A1 (en) 1998-06-11
FR2756826B1 (en) 1999-01-08
CN1126739C (en) 2003-11-05
NO992731D0 (en) 1999-06-04
DK0937043T3 (en) 2002-06-10
NZ336111A (en) 2000-03-27
EP0937043B1 (en) 2002-03-06
NO313589B1 (en) 2002-10-28
AU7624398A (en) 1998-06-29
CN1239951A (en) 1999-12-29
JP3872821B2 (en) 2007-01-24
AU719208B2 (en) 2000-05-04
NO992731L (en) 1999-06-04
ATE214051T1 (en) 2002-03-15
WO1998024765A1 (en) 1998-06-11
FR2756826A1 (en) 1998-06-12
CA2274133C (en) 2003-09-16
PT937043E (en) 2002-07-31
HK1023346A1 (en) 2000-09-08
JP2001505214A (en) 2001-04-17
PL189372B1 (en) 2005-07-29
HUP0001773A3 (en) 2002-12-28
DE69710909D1 (en) 2002-04-11
HUP0001773A2 (en) 2000-11-28
ZA9710960B (en) 1998-06-15
EP0937043A1 (en) 1999-08-25

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