Nothing Special   »   [go: up one dir, main page]

ES2160308T3 - Nuevos derivados amino-metil-heterociclicos, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen. - Google Patents

Nuevos derivados amino-metil-heterociclicos, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.

Info

Publication number
ES2160308T3
ES2160308T3 ES97402655T ES97402655T ES2160308T3 ES 2160308 T3 ES2160308 T3 ES 2160308T3 ES 97402655 T ES97402655 T ES 97402655T ES 97402655 T ES97402655 T ES 97402655T ES 2160308 T3 ES2160308 T3 ES 2160308T3
Authority
ES
Spain
Prior art keywords
methyl
pharmaceutical compositions
compositions containing
preparation procedure
new amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97402655T
Other languages
English (en)
Inventor
Daniel Lesieur
Pascal Carato
Jean-Paul Bonte
Patrick Depreux
Daniel-Henri Caignard
Mark Millan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ADIR SARL
Original Assignee
ADIR SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ADIR SARL filed Critical ADIR SARL
Application granted granted Critical
Publication of ES2160308T3 publication Critical patent/ES2160308T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/16—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Thiazole And Isothizaole Compounds (AREA)

Abstract

DERIVADOS DE FORMULA GENERAL (I): DONDE A, X, R SUB,1}, Y, N Y AR ESTAN DEFINIDOS EN LA DESCRIPCION. MEDICAMENTOS.
ES97402655T 1996-11-08 1997-11-06 Nuevos derivados amino-metil-heterociclicos, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen. Expired - Lifetime ES2160308T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9613652A FR2755690B1 (fr) 1996-11-08 1996-11-08 Nouveaux derives aminomethyl heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
ES2160308T3 true ES2160308T3 (es) 2001-11-01

Family

ID=9497457

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97402655T Expired - Lifetime ES2160308T3 (es) 1996-11-08 1997-11-06 Nuevos derivados amino-metil-heterociclicos, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.

Country Status (20)

Country Link
US (1) US5919784A (es)
EP (1) EP0841330B1 (es)
JP (1) JPH10139780A (es)
CN (1) CN1072655C (es)
AT (1) ATE202564T1 (es)
AU (1) AU726681B2 (es)
BR (1) BR9705456A (es)
CA (1) CA2220996A1 (es)
DE (1) DE69705376T2 (es)
DK (1) DK0841330T3 (es)
ES (1) ES2160308T3 (es)
FR (1) FR2755690B1 (es)
GR (1) GR3036472T3 (es)
HK (1) HK1010869A1 (es)
HU (1) HUP9701921A3 (es)
NO (1) NO309477B1 (es)
NZ (1) NZ329133A (es)
PL (1) PL323032A1 (es)
PT (1) PT841330E (es)
ZA (1) ZA9710055B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6177422B1 (en) * 1996-05-29 2001-01-23 Warner-Lambert Company Benzoxazinone dopamine D4 receptor antagonists
US6107313A (en) * 1998-10-02 2000-08-22 Combichem, Inc. Dopamine receptor antagonists
FR2803298A1 (fr) * 1999-12-30 2001-07-06 Adir Nouvelles urees lineaires ou cycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US7794761B2 (en) * 2000-04-13 2010-09-14 Seroctin Research & Technology, Inc. Methods for inducing anti-anxiety and calming effects in animals and humans
US20040192669A1 (en) 2000-04-13 2004-09-30 Rosenfeld Mark J. Novel compounds for use in weight loss and appetite suppression in humans
GB0227240D0 (en) * 2002-11-21 2002-12-31 Glaxo Group Ltd Compounds
AR047759A1 (es) * 2003-09-26 2006-02-22 Vertex Pharma Derivados de fenil - piperazina como moduladores de receptores muscarnicos
US7524877B2 (en) 2003-11-20 2009-04-28 Seroctin Research & Technology, Inc. Compounds for use in weight loss and appetite suppression in humans
JP5337259B2 (ja) 2009-02-26 2013-11-06 レビバ ファーマシューティカルズ，インコーポレーテッド アリールピペラジン誘導体の組成物、合成および利用方法
EP2563143A4 (en) * 2010-04-29 2013-09-25 Merck Sharp & Dohme SUBSTITUTED 1,3-BENZOTHIAZOL-2 (3H) -ONE AND [1,3-] THIAZOLO- [5,4-B] PYRIDINE-2 (-1H) -ONE AS POSITIVE ALLOSTERE MODULATORS OF MGLUR2
US10428030B2 (en) * 2015-10-30 2019-10-01 Trillium Therapeutics Heterocycle derivatives and their use for the treatment of CNS disorders
AU2023235233A1 (en) 2022-03-14 2024-09-12 Slap Pharmaceuticals Llc Multicyclic compounds

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX173362B (es) * 1987-03-02 1994-02-23 Pfizer Compuestos de piperazinil heterociclicos y procedimiento para su preparacion
FR2637286A1 (fr) * 1988-10-04 1990-04-06 Adir Nouveaux derives benzoxazolinoniques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
FR2667068B1 (fr) * 1990-09-26 1994-09-09 Adir Nouvelles amines alkyl heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
US5234924A (en) * 1990-09-26 1993-08-10 Adir Et Compagnie Benzothiazine and benzothiazole compounds useful as analgesics
DE4037427A1 (de) * 1990-11-24 1992-05-27 Kali Chemie Pharma Gmbh Heterocyclisch substituierte piperazinoalkylbenzoxazin und -thiazin-verbindungen sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
FR2674524B1 (fr) * 1991-03-25 1993-05-21 Adir Nouveaux amides alkyl heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2702214B1 (fr) * 1993-03-05 1995-04-14 Adir Nouveaux composés (aryl(alkyl)carbonyl)-hétérocycliques, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent.
FR2717810B1 (fr) * 1994-03-22 1996-04-26 Adir Nouvelles aminoalkyl benzoxazolinones et benzothiazolinones, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
AU687155B2 (en) * 1994-03-22 1998-02-19 Les Laboratoires Servier Novel aminoalkyl benzothiazolinones, process for their preparation and the pharmaceutical compositions which contain them

Also Published As

Publication number Publication date
DE69705376T2 (de) 2002-02-14
AU4440397A (en) 1998-05-14
DK0841330T3 (da) 2001-09-03
BR9705456A (pt) 2000-02-08
ATE202564T1 (de) 2001-07-15
NO975121D0 (no) 1997-11-07
PL323032A1 (en) 1998-05-11
AU726681B2 (en) 2000-11-16
JPH10139780A (ja) 1998-05-26
ZA9710055B (en) 1998-05-25
EP0841330A1 (fr) 1998-05-13
CN1182083A (zh) 1998-05-20
PT841330E (pt) 2001-10-30
HUP9701921A2 (hu) 1998-12-28
HU9701921D0 (en) 1998-01-28
FR2755690A1 (fr) 1998-05-15
DE69705376D1 (de) 2001-08-02
NO975121L (no) 1998-05-11
FR2755690B1 (fr) 1998-12-18
NZ329133A (en) 1998-08-26
EP0841330B1 (fr) 2001-06-27
US5919784A (en) 1999-07-06
GR3036472T3 (en) 2001-11-30
HK1010869A1 (en) 1999-07-02
NO309477B1 (no) 2001-02-05
CN1072655C (zh) 2001-10-10
HUP9701921A3 (en) 1999-03-29
CA2220996A1 (fr) 1998-05-08

Similar Documents

Publication Publication Date Title
AR001440A1 (es) Nuevos taxoides, su preparación y composiciones farmacéuticas que los contienen.
AR027162A1 (es) Compuestos de 2-fenil-3-fenoxilo-feniltio-benzotiofeno, sales farmaceuticamente aceptables de los mismos y composiciones farmaceuticas que los contienen
ES2144192T3 (es) Nuevos derivados de 1-fenil-2-dimetil-amino-metil-ciclohexan-1-ol, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
SE9504661D0 (sv) New compounds
ES2095432T3 (es) Derivados de 2,4-tiazolidin-diona, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
ES2075202T3 (es) Nuevas arilpiridazinas, su preparacion, su utilizacion, y medicamentos que las contienen.
WO2000061541A3 (en) Pharmaceutical compounds
ES2102475T3 (es) Nuevas alquil-amidas heterociclicas, su procedimiento de preparacion y composiciones farmaceuticas que las contienen.
MX9203394A (es) Benzazepinas substituidas, su preparacion y composiciones farmaceuticas que contienen las mismas.
ES2158327T3 (es) Derivados de benzo(g)quinolina.
ES2107284T3 (es) Nuevas n-piridil-carboxamidas, su procedimiento de preparacion y composiciones farmaceuticas que las contienen.
MX9204563A (es) Nuevos derivados de la (2-alquil-3-piridil)-metilpiperazina y composicion farmaceutica que los comprende.
ES2160308T3 (es) Nuevos derivados amino-metil-heterociclicos, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
ATE178332T1 (de) Benzothiadiazinderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zuzammensetzungen
ATE319715T1 (de) Antikonvulsive pseudofructopyranose sulfamate
ES2062137T3 (es) Utilizacion de 5'-deoxi-5'-metil-tioadenosina, s-adenosilmetionina y sus sales para la preparacion de composiciones farmaceuticas reductoras de seborrea.
ES2111871T3 (es) Nuevos derivados de aminoacidos, su procedimiento de preparacion y composiciones farmaceuticas que los contienen.
DK0842185T3 (da) Ara-C-derivater
ES2105605T3 (es) Antagonistas de taquiquinina, su preparacion y utilizacion en formulaciones farmaceuticas.
MX9301235A (es) DERIVADOS 1,4-DIOXINO(2,3-B)PIRIDINA. á
SE9504662D0 (sv) New compounds
ES2086195T3 (es) Nuevos derivados pseudopeptidicos de actividad antagonista de la bradiquinina, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
ES2182090T3 (es) Nuevos derivados de pirrol.
AR004476A1 (es) Compuestos biciclicos, su preparacion y su utilizacion en composiciones farmaceuticas
ES2095431T3 (es) N-(isoquinolein-5-il)-sulfonil-azacicloalcanos, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 841330

Country of ref document: ES